Salil Pathak

Post-Doctoral Associate, Department of Biomedical Sciences

Post-Doctoral Associate, Department of Biomedical Sciences


PhD, Centre for Cellular and Molecular Biology, India

MS, Tezpur University, India

Summary

Salil is a Postdoctoral Associate in the Department of Biomedical Sciences at the University of Minnesota Medical School. He works with Dr. Matthew Slattery and Dr. Yi-Mei Yang. In his research, Salil is trying to understand how acute/chronic stress during various stages of development alters gene expression in the mouse brain and leads to disease. He integrates gene expression data with electrophysiology and mouse behavior to understand the stress response. He received his Ph.D. from the Centre for Cellular and Molecular Biology, India for his work on the role of histone demethylases in stress-induced depression.

Research

Publications

I. Publications
  • Chao, Owen Y., Salil S. Pathak, Hao Zhang, Nathan Dunaway, Jay-Shake Li, Claudia Mattern, Susanne Nikolaus, Joseph P. Huston, and Yi-Mei Yang. "Altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autism." Molecular Brain, 13, (2020), 111.
  • Chao, Owen Y., Ezequiel Marron Fernandez de Velasco, Salil Saurav Pathak, Swati Maitra, Hao Zhang, Lisa Duvick, Kevin Wickman, Harry T. Orr, Hirokazu Hirai, and Yi-Mei Yang. "Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism." Neuropsychopharmacology 45, no. 7 (2020): 1159-1170.
  • Pathak, Salil Saurav, Dong Liu, Tianbao Li, Nuria de Zavalia, Lei Zhu, Jin Li, Ramanujam Karthikeyan et al. "The eIF2? kinase GCN2 modulates period and rhythmicity of the circadian clock by translational control of Atf4." Neuron 104, no. 4 (2019): 724-735.
  • Liu, Dong, Adam Stowie, Nuria de Zavalia, Tanya Leise, Salil Saurav Pathak, Lester R. Drewes, Alec J. Davidson, Shimon Amir, Nahum Sonenberg, and Ruifeng Cao. "mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction." Proceedings of the National Academy of Sciences 115, no. 14 (2018): E3296-E3304.
  • Pathak, Salil Saurav, Swati Maitra, Sumana Chakravarty, and Arvind Kumar. "Histonelysine demethylases of JMJD2 or KDM4 family are important epigenetic regulators in reward circuitry in the etiopathology of depression." Neuropsychopharmacology 42, no. 4 (2017): 854-863.
  • Chakravarty, Sumana, Priya Jhelum, Unis Ahmad Bhat, Wenson D. Rajan, Swati Maitra, Salil S. Pathak, Anant B. Patel, and Arvind Kumar. "Insights into the epigenetic mechanisms involving histone lysine methylation and demethylation in ischemia induced damage and repair has therapeutic implication." Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863, no. 1 (2017): 152-164.
  • Chakravarty, Sumana, Salil Saurav Pathak, Swati Maitra, Nitin Khandelwal, Karisetty Bhanu Chandra, and Arvind Kumar. "Epigenetic regulatory mechanisms in stress-induced behavior." In International review of neurobiology, vol. 115, pp. 117-154. Academic Press, 2014.