Bernadette Gillick, PhD, MSPT, PT

Assistant Professor, McKnight Land Grant Professor, Division of Physical Therapy

Bernadette Gillick

Contact Info

gillick@umn.edu

Office Address:
Division of Physical Therapy
311 Children's Rehab Ctr
426 Church Street SE
Minneapolis, MN 55455

Mailing Address:
Division of Physical Therapy
MMC 388
420 Delaware St SE
Minneapolis, MN 55455

Lab Address:
Room 320
426 Church St. SE
Minneapolis, MN 55455-0222

Assistant Professor, McKnight Land Grant Professor, Division of Physical Therapy

Assistant Professor, McKnight Land Grant Professor, Division of Rehabilitation Science

Faculty, Graduate Program in Neuroscience


PhD, University of Minnesota (Rehabilitation Science/Minor: Neuroscience), 2011

Advanced MS, Chicago Medical School (Neurologic Physical Therapy), 1997

BS, Marquette University (Physical Therapy), 1993; BA, Marquette University (Psychology), 1991

Summary

Research interests in cortical plasticity and recovery from neurologic insult across the lifespan. Her research encompasses the use of different forms of non-invasive brain stimulation (transcranial magnetic stimulation and transcranial Direct Current stimulation), in combination with behavioral training, for improved motor function. Current Teaching Responsibilities include Research, Pediatric Rehabilitation, and Seminar in Academia.

Awards & Recognition

  • Medical School: Dean’s Grant Preparation Award – 2018-Present
  • Clinical and Translational Science Institute Annual Conference Keynote Speaker – 2018
  • Representative, Global Professional Education Committee International Alliance of Academies of Childhood Disability – 2017-Present
  • McKnight Land-Grant Professor – 2017-2019
  • Legislation Speaker at the MN Capitol with President Kaler – 2017
  • APTA - Eugene Michels Outstanding New Investigator Award – 2017
  • New Mexico Brain Injury Conference, Plenary Speaker – 2017
  • Australian Consulate Cerebral Palsy Alliance Award, NYC, NY - 2016
  • MN Governor Dayton Pediatric Stroke Awareness Month May 2016, Proclamation Co-Author
  • American Academy of Cerebral Palsy and Developmental Medicine, Plenary Speaker - 2015
  • Graduation Speaker, Doctor of Physical Therapy – 2013, 2015, 2018
  • NIH Fellowship - 2015 Summer Institute on Randomized Behavioral Clinical Trials.
  • NIH K01 Career Development Award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, 2014
  • Developmental Medicine Child Neurology Journal - Editor’s Choice Manuscript - 2014
  • University of Minnesota Clinical and Translational Science Institute -KL2, 2013
  • American Physical Therapy Association Section on Pediatrics Dissertaion Award, 2013
  • University of Minnesota Clinical and Translational Science Institute - Pre-K Pilot Grant, 2012
  • American Academy of Cerebral Palsy and Developmental Medicine Arnold Award Nominee, 2012
  • Minnesota Medical Foundation New Faculty Grant, 2012
  • University of Minnesota Clinical and Translational Science Institute - Biostatistical Design and Analysis Center Grant, 2012
  • Archives of Physical Medicine and Rehabilitation Top 25 Article Summer 2012
  • University of Minnesota Clinical and Translational Science Institute Best Poster Award. 2012

Professional Associations

  • International Alliance of Academies of Childhood Disability – Representative on Global Professional Education Committee
  • University of Minnesota - Rehabilitation Science Faculty
  • University of Minnesota - Biomedical Engineering Faculty
  • University of Minnesota – Center for Neuroimaging
  • American Academy of Cerebral Palsy and Developmental Medicine
  • American Congress of Rehabilitation Medicine
  • American Physical Therapy Association
  • Society for Neuroscience
  • PUPS Great Lakes Pediatric PT Professor Group

Research

Research Summary/Interests

Current Studies

  • Perinatal Stroke: Understanding Brain Reorganization through Infant Neuroimaging and Neuromodulation (Clinical Trials.gov # NCT02743728) (z.umn.edu/infant)

Research Funding Grants

Current Research Support

Shepherd Trust/Jensen Family
“Gillick Pediatric Neuromodulation Laboratory”
Dates: 2020-2021
PI: Gillick

NIH 1R21HD097575-01A1
“Perinatal Brain Injury: Identifying Cortical Excitability and Circuitry through Multi-Modal Assessment”
August 2019-July 2021
PI: Gillick

NIH R01HD033486
“Flexibility in Infant Skill Acquisition”
September 2018-August 2022
Scientific Advisory Committee Member: Gillick

Canadian Institutes of Health Research
“The Alberta Perinatal Stroke Program: Neuromodulation to Optimize Outcomes”
July 2015-June 2022
Co-I: GIllick

Australia’s National Health and Medical Research Council (NHMRC1078877)
“Randomized trial of Early Rehabilitation for Congenital Hemiplegia (REACH)”
January 2019-January 2022
Co-I: GIllick

U of M Grant-in-Aid of Research, Artistry and Scholarship (GIA)
“Mindful Breathing and Neuromodulation for Depression in Adolescents and Young Adults”
January 2019-June 2020
Co-I: Gillick

NIH National Center of Neuromodulation for Rehabilitation Pilot Project Program (NC NM4R)
“Comparing Two Montages of Transcranial Direct Current Stimulation in Pediatric Stroke”
July 1, 2018-December 31, 2019, Competitive Supplement Award December 1, 2019-May 31, 2020
PI: Gillick

Past Research Support

Maslowski Charitable Trust
“Understanding how the infant bran both recovers and develops after injury due to stroke”
2018-2019
PI: Gillick

Shepherd Trust/Jensen Family
“Gillick Pediatric Neuromodulation Laboratory”
2018-2019
PI: Gillick

NIH/NICHD: K01 HD078484-01A1
“Novel Neuromodulatory Intervention in the Rehabilitation of Pediatric Hemiparesis”
September 2014-June 2019
PI: Gillick

UMN Medical School Faculty Research Award
“Comparing Two Montages of Transcranial Direct Current Stimulation in Unilateral Cerebral Palsy”
June 1, 2018-May 31, 2019
PI: Gillick

UMN Institute for Engineering in Medicine
“Establishing a computational noninvasive neuromodulation consortium at the University of Minnesota”
May 14, 2018-May 14, 2019
Co-I: Gillick

UMN Office of Discovery and Translation Community Discovery Program for Child Health Innovation
“Development of Interactive Software for use in Pediatric Stroke Rehabilitation”
January 1, 2018-December 31, 2018
Co-I: Gillick

UMN/Winona State University Collaborative Award
“MN State Fair 2018 Research Project “Would you take a ride on the giant research slide?”
August 2018
PI: Gillick

NIH 1 S10 OD021721-01
“MRI-compatible integrated NIRS/EEG system for applications to Clinical Neuroscience”
April 1, 2016-March 31, 2018
User: Gillick

UMN Academic Health Center Seed Grant
“Perinatal Stroke: Understanding Brain Reorganization through Infant Neuroimaging and Measures of Neuro-excitability”
April 2016-December 2017
PI: Gillick

Northeast Amyotrophic Lateral Sclerosis Consortium
“Effect of Mexiletine on Cortical Hyperexcitability in Sporadic Amyotrophic Lateral Sclerosis”
September 1, 2015- August 31, 2017
Collaborator: Gillick

Australian Cerebral Palsy Alliance
“Perinatal Stroke: Understanding Brain Reorganization through Infant Neuroexcitability and Neuroimaging”
April 1, 2016-March 31, 2017
PI: Gillick

Foundation for Physical Therapy Magistro Family Foundation Research Grant
"Transcranial Direct Current Stimulation (tDCS) and Constraint-Induced Movement Therapy (CIMT) in Pediatric Hemiparesis."
January 2015-December 2016
PI: Gillick

Cerebral Palsy International Research Foundation (CPIRF) Research Grant
"Transcranial Direct Current Stimulation and Constraint-Induced Movement Therapy in Pediatric Hemiparesis"
January 2014-December 2016
PI: Gillick

Medical School/UMF Faculty Research and Equipment Award
April 2015-April 2017
Collaborator: Gillick

Medical School/UMF Faculty Equipment Award
April 2015-April 2017
User: Gillick

Instrumentarium Science Foundation, Finland
“Mechanisms of neuromodulatory transcranial magnetic stimulation in humans: changes in neurochemistry and functional connectivity assessed by functional magnetic resonance imaging and spectroscopy at 7T”
Jan 2016-December 2016
Collaborator: Gillick

UMN Medical School Innovation Grant
“Mechanisms of Neuromodulation Interventions: Influence on Human Neurochemistry and Functional Connectivity”
April 2015-December 2016
Co-I: Gillick

University of Minnesota PsychDrive
“Impact of Transcranial Direct Current Stimulation on Affect Laden Episodic Memory Consolidation”
September 2014-August 2016
Co-I: Gillick

Clinical and Translational Science Institute- Biostatistical Design and Analysis Center
“Longitudinal Outcomes in rTMS/CIMT”
September 2013-August 2015
PI: Gillick

Clinical and Translational Science Institute - KL2 Grant
"Non-Invasive Brain Stimulation and Constraint-Induced Movement Therapy in Pediatric Hemiparesis"
September 2013-September 2014
PI: Gillick

Clinical and Translational Science Institute - Biostatistical Design and Analysis Center
"TMS and EEG Mapping of Motor Cortex"
January 2013-June 2014
PI: Gillick

Clinical and Translational Science Institute - Biostatistical Design and Analysis Center
"Safety of transcranial Direct Current Stimulation in Pediatric Hemiparesis"
March 2012-March 2014
PI: Gillick

Minnesota Medical Foundation
"Safety of transcranial Direct Current Stimulation in Pediatric Hemiparesis"
March 2012-March 2014
PI: Gillick

Clinical and Translational Science Institute - Pre-K Pilot Grant
"Safety of transcranial Direct Current Stimulation in Pediatric Hemiparesis"
March 2012-March 2014
PI: Gillick

National Institutes of Health - RC1
"Pediatric Hemiparesis: Synergistic Treatment using Repetitive Transcranial Magnetic Stimulation (rTMS) and Contraint-Induced Therapy (CIT)"
2009-2011
PI: James Carey (Graduate Research Assistant - Gillick)

National Institutes of Health - R01
"rTMS and Motor Learning Training to Promote Recovery from Hemiparesis"
2007-2009
PI: James Carey (Graduate Research Assistant - Gillick)

Publications

  • Rich TL, Nemanich S (Co-First Authors), Chen CY, Sutter EN, Feyma T, Krach LE, Gillick BT. ‘Ipsilateral corticospinal tract excitability contributes to the severity of mirror movements in unilateral cerebral palsy: A case series’. Clinical EEG and Neuroscience. (In Press).
  • Heidi Grohn, Bernadette T Gillick, Ivan Tkac, Petr Bednarik, Daniele Mascali, Dinesh Kumar Deelchand, Shalom Michaeli, Gregg D Meekins, Michael J Leffler-McCabe, Colum Doan MacKinnon, Lynn E Eberly, Silvia Mangia, ‘Influence of Repetitive Transcranial Magnetic Stimulation on Human Neurochemistry and Functional Connectivity: a Pilot MRI/MRS Study at 7 T Journal.’ Frontiers in Neuroscience:Brain Imaging Methods. (In Press).
  • Kowalski J, Nemanich S, Nawshin T, Chen M, Peyton C, Zorn E, Hickey M, Rao R, Georgieff M, Rudser K, Gillick BT. ‘Motor Evoked Potentials as Potential Biomarkers of Early Atypical Corticospinal Tract Development in Infants with Perinatal Stroke’. J Clin Med. 2019 Aug 13;8(8).
  • Nemanich ST, Mueller B, Gillick BT. ‘Neurite orientation dispersion and density imaging (NODDI) quantifies corticospinal tract microstructural organization in children with unilateral cerebral palsy’ Human Brain Mapping, 2019 Jul 2.
  • Nemanich ST, Rich TL, Chen CY, Menk JS, Rudser KD, Chen M, Meekins G, Gillick BT. “Safety and Feasibility of Transcranial Magnetic Stimulation as an Exploratory Assessment of Corticospinal Connectivity in Infants After Perinatal Brain Injury: an Observational Study” Physical Therapy, 2019 Jun 1:99(6):689-700.
  • Nemanich ST, Rich TL, Chen CY, Menk J, Rudser K, Chen M, Meekins G, Gillick BT. Influence of Combined Transcranial Direct Current Stimulation and Motor Training on Corticospinal Excitability in Children With Unilateral Cerebral Palsy. Front Hum Neurosci, 2019 Apr 24; 13:137.
  • Nemanich ST, Gordon A, Friel K, Gillick BT. ‘Bimanual skill learning after transcranial direct current stimulation in children with unilateral cerebral palsy: a brief report.’ Developmental Neurorehabilitation, 2019 Apr 3:1-5.
    Rich TL, Gillick BT. ‘Electrode Placement in Transcranial Direct Current Stimulation- How reliable is the determination of C3/C4?’ Brain Sciences, 2019 Mar 22; 9(3).
  • Keller-Ross, ML, Chantigian DP, Chen M, Rich TL, Chen CY, Gillick BT. “Stability of the Cardiovascular Response during Single-Pulse TMS in Pediatric Stroke.” Brain Stimulation, 2018, Brain Stimulation. 2019 Mar - Apr; 12(2):371-373. 
  • Lixandrão MC, Stinear JW, Rich T, Chen CY, Feyma T, Meekins GD, Gillick BT. “EMG breakthrough during cortical silent period in congenital hemiparesis: A descriptive case series.” Brazilian Journal of Physical Therapy, 2018, Braz J Phys Ther. 2018 Nov 21. pii: S1413-3555(17)30677-9. 
  • Rich T, Nemanich ST, Chen M, Friel KM, Feyma T, Krach LE, Nawshin T, Meekins G, Gillick BT. "Transcranial direct current stimulation (tDCS) paired with occupation-centered bimanual training in children with unilateral cerebral palsy: A preliminary study" Neural Plasticity, 2018, Nov 5;2018.
  • Gillick BT, Rich T, Nemanich S, Chen CY, Menk J, Mueller BA, Chen M, Ward M, Meekins G, Feyma T. Krach L, Rudser K. ‘Transcranial direct current stimulation and constraint-induced therapy in cerebral palsy: a randomized, blinded, sham-controlled clinical trial’, European Journal of Paediatric Neurology 2018, 22; 358-368
  • Gillick BT, Gordon AM, Feyma T, Krach LE, Carmel J, Rich TL, Bleyenheuft Y, Friel K. "Non-Invasive Brain Stimulation in Children with Unilateral Cerebral Palsy: A Protocol and Risk Mitigation Guide", Frontiers in Pediatrics, 2018, 6(56).
  • Rich T, Menk J, Rudser KD, Chen M, Meekins GD, Pena E, Feyma T, Bawroski K, Bush C, Gillick BT. “Determining electrode placement for transcranial direct current stimulation: A comparison of electroencephalogram versus transcranial magnetic stimulation-guided methods”. Clinical EEG and Neuroscience. (In Press).
  • Chen CY, McGee C, Rich T, Prudente C, Gillick BT. “Reference Values of Intrinsic Muscle Strength of the Hand of Adolescents and Young Adults”. Journal of Hand Therapy, 2017. (In press).
  • Rich TL, Menk JS, Rudser KD, Chen M, Meekins GD, Peña E, Feyma T, Bawroski K, Bush C, Gillick BT. Determining electrode placement for transcranial direct current stimulation: A comparison of electroencephalogram versus transcranial magnetic stimulation guided methods. Clin EEG Neurosci 2017 May.
  • Chen CY, Georgieff M, Elison J, Chen M, Stinear J, Mueller B, Rao R, Rudser K, Gillick B. “Understanding Brain Reorganization in Infants with Perinatal Stroke through Neuroexcitability and Neuroimaging: Study Protocol, Pediatric Physical Therapy, 2017 Apr;29(2):173-178.
  • Froehle E, Gillick B. “’Research’ what you say: I did not suffer a stroke, I survived one.” Journal of Humanities in Rehabilitation, Fall 2016. 
  • Chen CY, Rich TR, Cassidy JM, Gillick BT. “Corticospinal Excitability in Children with Congenital Hemiparesis.” Brain Sci. 2016 Oct 20;6(4).
  • Bikson M, Grossman P, Thomas C, Zannou AL, Jiang J, Adnan T, Mourdoukoutas AP, Kronberg G, Truong D, Boggio P, Brunoni AR, Charvet L, Fregni F, Fritsch B, Gillick B, Hamilton RH, Hampstead BM10, Jankord R11, Kirton A12, Knotkova H13, Liebetanz D14, Liu A15, Loo C16, Nitsche MA, Reis J, Richardson JD, Rotenberg A, Turkeltaub PE, WoodsAJ. “Safety of Transcranial Direct Current Stimulation: Evidence Based Update 2016.” Brain Stimulation, 2016 Sep-Oct;9(5):641-61. 
  • TL Rich, J Cassidy, A Van Heest, J Carey, LE Krach, J Menk, BT Gillick, “Stability of Stereognosis after Paediatric Repetitive Transcranial Magnetic Stimulation and Constraint-Induced Movement Therapy Clinical Trial ”. Developmental Neurorehabilitation, 2016 Mar 17:1-4.
  • TL Rich, J Menk, LE Krach, T Feyma, BT Gillick. Repetitive Transcranial Magnetic Stimulation/Behavioral Intervention Clinical Trial: Long-Term Follow-Up of Outcomes in Congenital Hemiparesis. Journal of Child and Adolescent Psychopharmacology, 2016 Feb 23.
  • Gillick BT, Rich T, Chen M, Meekins GD. Case Report of Vasovagal Syncope Associated with Single Pulse TMS in a Health Adult Participant, BMC Neurology, 2015 Dec 1;15:248.
  • Gillick B, Menk J, Mueller B, Meekins G, Krach L, Feyma T, Rudser K.“Synergistic Effect of Combined transcranial Direct Current Stimulation/Constraint-Induced Movement Therapy in Children and Young Adults with Hemiparesis: Protocol”, BMC Pediatrics. 2015 Nov 12;15:178.
  • Cassidy JM, Carey JR, Lu C, Krach LE, Feyma T, Gillick BT. "Ipsilesional Motor-Evoked Potential Absence in Pediatric Hemiparesis Impacts Tracking Accuracy of the Less Affected Hand."Research in Developmental Disabilities, Accepted for publication, Sept 2015.
  • Gillick BT, Feyma T, Menk J, Usset M, Vaith A, Wood T, Worthington R, Krach LE. "Safety and Feasibility of Transcranial Direct Current Stimulation in Pediatric Hemiparesis: A Randomized Controlled Pilot Study." Physical Therapy 2015:95(3):337-349.
  • Gillick BT, Krach LE, Feyma T, Rich TR, Moberg KJ, Menk J, Cassidy J, Kimberley T, Carey JR. "Safety of primed repetitive transcranial magnetic stimulation and modified constraint-induced movement therapy in pediatric hemiparesis." Arch Phys Med Rehabil. 2015:96 (4) S104-S113.
  • Kimberley TJ, Borich MR, Schmidt R, Carey JR, Gillick B."Focal hand dystonia: individualized intervention with repeated application of repetitive transcranial magnetic stimulation." Arch Phys Med Rehabil. 2015:96 (4) S122-8.
  • Gillick BT, Kirton A, Carmel JB, Minhas P, Bikson M. "Pediatric stroke and transcranial direct current stimulation: methods for rational individualized dose optimization." Frontiers in Human Neuroscience. 2014. 8:739.
  • Gillick BT, Krach LE, Feyma T, Rich TL, Moberg K, Thomas W, Cassidy JM, Menk J, Carey JR. "Primed Low-Frequency Repetitive Transcranial Magnetic Stimulation and Constraint-Induced Movement Therapy Randomized Trial for Pediatric Hemiparesis." Developmental Medicine Child Neurology. 2014; 56(1):44-52.
  • Cassidy JM, Gillick BT, Carey JR. "Priming the Brain to Capitalize on Metaplasticity in Stroke Rehabilitation." Physical Therapy. 2013; 94(1):139-50.
  • Gillick BT, Zirpel L. "Neuroplasticity: An Appreciation from Synapse to System." Archives of Physical Medicine and Rehabilitation. 2012; 93(10):1846-55.
  • Gillick B, Effects of constraint-induced movement therapy (CIMT) on gross motor outcomes.Pediatric Physical Therapy. 2012; 24(3):300.
  • Gillick BT, Rheault W, Marshall W, Stoecker J. “Mobility Criteria for Upright Sitting with Patients in the Neuro/Trauma Intensive Care Unit: An Analysis of Length of Stay and Functional Outcomes.” Neurohospitalist. 2011;1(4):172-177.
  • Gillick BT, Koppes A. “Gross motor outcomes in children with hemiparesis involved in a modified constraint induced therapy program”. J Ped Rehab Med. 2010: 171-175.
  • Carey JR, Anderson DC, Gillick BT, Whitford M, Pascual-Leone A. “6-Hz Primed Low-Frequency rTMS to Contralesional M1 in Two Cases with Middle Cerebral Artery Stroke.” Neurosci Lett. 2010;469(3):338-342.
  • Gillick BT, Kloth LC, Starsky A, Cincinelli-Walker L. “Management of postsurgical hyperhidrosis with direct current and tap water.” Phys Ther. 2004;84:262-267.

Clinical

Clinical Experience Statement

Children’s Hospital and Regional Medical Center Seattle, WA- 2005- 2011; Anchorage School District Anchorage, AK Clinical Supervisor of Physical Therapy- 2002-2004; Providence Alaska Medical Center Anchorage, AK Manager of Rehabilitation- 1999-2001; Rehabilitation Institute of Chicago / Loyola University Medical Center Chicago, IL 1993-1999; Institute for Latin American Concern Santa Domingo, Dominican Republic Clinical Instructor for Marquette and Creighton Physical Therapy Programs- 1998