Demetri Yannopoulos, MD

Professor of Medicine, Center for Resuscitation Medicine

Demetri Yannopoulos

Contact Info

Mailing Address:
420 Delaware Street SE
MMC 508 Mayo
8508A (Campus Delivery Code)
Minneapolis, MN 55455

Administrative Assistant Name
Kathy Vang

Administrative Email

Additional Locations

M Health Fairview Clinics & Surgery Center

Professor of Medicine, Center for Resuscitation Medicine

Research Director, Interventional Cardiology

Director, Resuscitation Medicine

Faculty, PhD Program in Integrative Biology and Physiology


Medical School, University of Athens Medical School, Athens, Greece

Residency, University of Minnesota, Minneapolis, MN

Fellowship, Johns Hopkins University, Baltimore, MD


Born in London, UK, Dr. Yannopoulos received his M.D. from the University of Athens in Greece. He completed his medicine residency and general-cardiology fellowship at the University of Minnesota. Following an interventional-cardiology fellowship at Johns Hopkins University in Baltimore, Maryland, Dr. Yannopoulos joined the University of Minnesota faculty in 2008. In March 2010, he became the research director for interventional cardiology.

Dr. Yannopoulos is board-certified in internal medicine, cardiology, and interventional cardiology. His clinical interests include emergent cardiac care, coronary-artery disease, and congenital and peripheral intervention.

Dr. Yannopoulos’s research involves cardiopulmonary resuscitation, hypothermia, and myocardial salvage during acute coronary syndromes. He is considered an authority in cardiorespiratory interactions and hypothermia during CPR. His work in the laboratories of Dr. Keith Lurie (at the University of Minnesota) and Dr. Henry Halperin (at Johns Hopkins University) has helped change current CPR practices.

Dr. Yannopoulos is a member of the American Heart Association’s CPR guidelines-writing committee, and of the basic life support and research working-group subcommittees. He also serves on the organization committee for the AHA’s Resuscitation Science Symposium (ReSS), the largest international conference addressing CPR and emergent cardiac/trauma care.

Dr. Yannopoulos is the recipient of two American Heart Association Young Investigator awards (2005 and 2008), and has received AHA and NIH grant support for his work in CPR devices designed to improve bloodflow and clinical outcomes.

Awards & Recognition

  • UMN Dean’s Distinguished Research Leadership Award, 2015
  • AHA Heart Association Heart & Stroke Hero Award, 2015
  • AHA Young Investigator Award in Resuscitation Science Symposium: “The Effect of Achieving Return of Spontaneous Circulation on Mitochondrial Respiration Following Prolonged Cardiac Arrest” w /Timothy Matsuura”, 2014
  • AHA Young Investigator Award in Resuscitation Science Symposium: “Sodium Nitroprusside-enhanced Cardiopulmonary Resuscitation Facilitates Intra-arrest Therapeutic Hypothermia in a Porcine Model of Prolonged Ventricular Fibrillation” w/ Guillaume Debaty”, 2014
  • Cardiovascular Division Innovator Award, 2014
  • AHA Young Investigator Award in Resuscitation Science Symposium: “Anesthetic Postconditioning with Sevoflurane during Cardiology Resuscitation Improves Cardiac Mitochondrial Function in a Pig Model of Cardiac Arrest” w/Timothy Matsuura”, 2013
  • Dr. Marvin & Hadassah Bacaner Research Award, 2011
  • AHA Young Investigator Award in Resuscitation Science Symposium: “Mechanical Post Conditioning with Chest Compression Pauses at the Initiation of CPR Prevents Neurological Dysfunction at 24 Hours in Pigs after 15 Minutes Untreated Ventricular Fibrillation”, 2011
  • AHA Young Investigator Award in Resuscitation Science Symposium: “Effects of Timing of Intra-CPR and Post Resuscitation Hypothermia on Myocardial Infarction Size in a Porcine Model of Ischemic Cardiac Arrest”, November 13, 2010
  • Best Resuscitation Abstract Award 2009 AHA Scientific Sessions: “Ventilation Rate and Use of the Impedance Threshold Device are Correlated with Hemodynamics During CPR in Human”, 2009
  • AHA Young Investigator Award Recipient in Resuscitation Science Symposium: “Mechanism of Pressure Transfer from the Thorax to the Cranium During Application of Negative Intrathoracic Pressure”, 2009
  • AHA Young Investigator Award Recipient. “Intra-CPR Hypothermia with and Without Volume Loading in an Ischemic Model of Cardiac Arrest”. Resuscitation Science Symposium, 2008
  • Member of the AHA/ECC BLS and Research Working Group Subcommittees, 2007
  • LW Miller award of clinical excellence and dedication to cardiovascular research, 2007
  • AHA Young Investigator Award Recipient. “Intrathoracic Pressure Regulator During Continuous-Chest-Compression Advanced Cardiac Resuscitation Improves Vital Organ Perfusion Pressures in a Porcine Model of Cardiac Arrest”, 2005

Professional Associations

Notable Leadership Roles

  • Member of the AHA/ECC 2010 CPR and emergent cardiac care guidelines writing committee
  • Member of the organization committee of the AHA, Resuscitation Science Symposium Conference (ReSS)
  • Member of the AHA/ECC BLS and Research Working Group Subcommittees





  • Interventional Cardiology


University of Minnesota Medical Center;University of Minnesota Physicians Heart at Fairview

Clinical Interests

Coronary artery disease and intervention; CPR; Interventional cardiology; Peripheral vascular disease; Resuscitation; Structural heart disease

Hospital Privileges

M Health Fairview University of Minnesota Medical Center, M Health Fairview Heart Clinic - Fridley


In The News

"Novel Cath Lab Transport Strategy May Boost Survival in Cardiac Arrest" - MedPage Today, 8/23/2017
"EDECMO 36 – Crushing the Nihilism of Cardiac Arrest – with Demetris Yannopoulos" -, 6/9/2017