Clark Chen
,
Credentials
MD, PhD

Professor, Lyle French Chair in Neurosurgery and Department Head
Preceptor, Medical Scientist Training Program (Combined MD/PhD Training Program)
Faculty, Masters Program in Stem Cell Biology
Faculty, Microbiology, Immunology and Cancer Biology (MICaB) Ph.D. Graduate Program
Biography

Bio

Dr. Chen is an internationally recognized brain tumor researcher and surgeon, with a dedicated interest in understanding how glioblastomas acquire resistance to radiation and chemotherapy. He is an NIH RO1-funded investigator whose research focuses on developing novel diagnostic and therapeutic approaches for brain tumor patients. He is also a leader in the study of DNA repair and gene therapy in brain tumors. His laboratory is housed in the University of Minnesota Masonic Cancer Center.

The recipient of several highly competitive research awards, Dr. Chen has won the:

  • Damon Runyon Fellowship Award
  • Sidney Kimmel Scholar Award
  • Burroughs Wellcome Foundation Career Award in Medical Sciences
  • Sontag Foundation Distinguished Scientist Award, the Doris Duke Foundation Clinical Scientist Award
  • Forbeck Scholar Award.

In 2016, Dr. Chen received the Presidential Award of Achievement from the President of Taiwan, Ma Ying-jeou. The award is given annually by the Taiwanese government to individuals of Taiwanese heritage who have made exceptional contributions to their profession.

Education

  • MD, Harvard Medical School, 2001
  • Neurosurgery, Massachusetts General Hospital, 2002-2007
  • Post-doctoral Fellow, Department of Radiation Oncology, Dana Farber Cancer Institute, 2006
  • Clinical Fellow, Radiosurgery, Department of Radiation Oncology, Massachusetts General Hospital, 2009
  • Clinical Fellow, Stereotactic Neurosurgery, Division of Neurosurgery, Beth Israel Deaconess Medical Center, 2009
  • PhD, Genetics, Harvard Medical School, 1999
  • MS, Epidemiology, Columbia University, 1993
  • BS, Stanford University, 1992

Professional Associations

  • American Association of Neurological Surgeons
  • Congress of Neurological Surgeons
  • American Association for Cancer Research
  • American Association for the Advancement of Science
  • Society of Neuro-Oncology
  • International Brain Mapping and Intraoperative Surgical Planning Society
  • American Society for Radiation Oncology

Board Certifications

American Board of Neurological Surgeons

In the Media

2-2020: Minnesota Physician: Glioblastoma: Activating an immune response
12-4-19: Minnesota Daily: New campus MRI machine to expand surgery capability
11-20-19:

10-4-19: The "Goldilocks" Principle for Curing Brain Cancer
7-24-19:

6-27-19: New drug helps surgeons spot brain tumors by turning them pink
1-27-19: Minnesota-developed NeuroBlate device saves brain cancer patients. But what's next?
12-3-18: U Doctor Examining How Laser Brain Surgery Affects Peoples' Lives
11-7-18: U of M begins trial for new brain cancer treatment
8-24-18: University of Minnesota Dr. on why McCain likely stopped his cancer treatment
8-24-18: High-profile glioblastoma deaths may be no coincidence
5-29-18: Doctor, patient reunited years after lifesaving surgery
1-8-18: Breakthrough Surgery Uses Laser To Remove Minnesota Man's Brain Tumor.

Executive Assistant:

Sally Sawyer
Administrative Phone: 612-624-6666 (hit 4 for the Academic Office)
Administrative Email: sallyann@umn.edu
Administrative Fax Number: 612-624-0644

Research Summary

Dr. Chen is a nationally recognized brain tumor researcher and surgeon, with a dedicated interest in understanding how glioblastomas acquire resistance to radiation and chemotherapy. He is an NIH RO1-funded investigator with research focused on developing novel diagnostic and therapeutic approaches for brain tumor patients. He is also a leader in the study of DNA repair and gene therapy in brain tumors.

View PubMed List

Clinical Summary

Brain tumors; minimally invasive cranial surgery; laser thermal ablation; endoscopy; oncolytic virus delivery; tractography-guided surgery; awake craniotomy