Michelle H. Biros, MD, MS, FACEP
Research Director, Department of Emergency Medicine
Contact Info
Research Director, Department of Emergency Medicine
Deputy Institutional Official, University of Minnesota Biomedical Research
Past Editor in Chief, Academic Emergency Medicine
Vulnerable Populations Advisor, University of Minnesota Medical School Institutional Review Board
MD, University of Minnesota Medical School, Emergency Medicine, 1982
University of Cincinnati, Emergency Medicine, 1982-1986 (Chief Resident of Emergency Medicine, 1985-1986)
University of Cincinnati, Emergency Medicine, 1984-1985
MS, University of Minnesota, Biochemistry, 1976
BA, College of St. Catherine, Chemistry, 1974
Summary
Dr. Biros is a professor of emergency medicine and vice chair of research for the Department of of Emergency Medicine. She is currently the principal investigator for the University of Minnesota hub of the National Institute of Neurological Disorders and Stroke (NINDS) funded Neurological Emergencies Treatment Trials network and the co-PI of the University of Minnesota regional coordinating center for the NINDS funded Stroke Net.
Expertise
emergency medicine; emergent neuroscience; biomedical and research ethics
Awards & Recognition
Research
Research Summary/Interests
The NETT is a nationally funded research network that aims to provide best treatments available for acute neurological emergencies. This includes but is not limited to studies on stroke, TBI, and Seizures. All studies within the NETT deal with acute medical and surgical management of potentially life threatening diseases for which current treatment is understudied or unstudied.
Among these research efforts are studies in which patients are too critically ill or injured to speak on their own behalf. Dr. Biros is a national expert on Exception from Informed Consent and studies community attitudes on this type of research.
Research Funding Grants
2014-present, NIH/NINDS, ATACH-II University of Minnesota Hub, Antihypertensive Treatment of Cerebral Hemorrhage
2013-present, NIH, VOICES University of Minnesota, Community VOICES (3): Community VOICES on informed consent in emergency situations
2011-present, NIH/NINDS, SHINE University of Minnesota Hub, Stroke Hyperglycemia Insulin Network Effort
2009-present, NIH/NINDS, POINT University of Minnesota Hub, Platelet Oriented Inhibition in New TIA and minor ischemic stroke
2006-present, NIH/NINDS, NETT University of Minnesota Hub, Neurological Emergencies Treatment Trials (NETT)
Publications
Hirshon JM, Hansoti B, Hauswald M, Sethuraman K, Kerr NL, Scordino D, Biros MH. Ethics in Acute Care Research: A Global Perspective and Research Agenda. Academic Emergency Medicine. December 2013: 20 (12): 1251-1258. doi: 10.1111/accm. 12271.
Dickert NW, Mah VA, Biros MH, Harney DM, Silbergleit R, Sugarman J, Veledar E, Weinfurt KP, Wright DW. Pentz RD. Consulting Communities When Patients Cannot Consent: A Multicenter Study of Community Consultation for Research in Emergency Settings. Crit Care Med. 20 13 Oct 1 8. [Epub ahead of print ]
Dickert NW, Mah VA, Baren JM, Biros MH, Govindarajan P, Pancioli A, Silbergleit R, Wright DW. Pentz RD. Enrollment in Research Under Exception from Informed Consent: The Patients' Experiences in Emergency Research (PEER) Study. Resuscitation. October 2013: 84 (10): 1416- 21. doi: 10.1016/j.resuscitation.2013.04.006. Epub 2013 Apr 16.
Biros M. The meaning of opt-out. Resuscitation. March 14, 2013; [Epub ahead of print] http://dx.doi.org/10.1016/j.resuscitation.2013.03.009 PMID: 23499899
Biros MH. Commentary: Does Community Consultation Matter? Academic Emergency Medicine. January 2013; 20 (1):104–105. PMID: 23570484
Iserson KV, Biros MH, Holliman C. Challenges in International Medicine: Ethical Dilemmas, Unanticipated Consequences, and Accepting Limitations. Academic Emergency Medicine. April 2012. [Epub ahead of print] DOI: 10.1111/j.1553-2712.2012.01376.x PMID: 22548491
Silbergleit R, Biros MH, Harney D, Dickert N, Baren J on behalf of the NETT Investigators. Implementation of the Exception From Informed Consent Regulations in a Large Multicenter Emergency Clinical Trials Network: The RAMPART Experience. Academic Emergency Medicine. April 2012; 19 (4): 448-454. PMID: 22506949
Biros M. The People Speak: Community Consultation in Emergency Research. Annals of Emergency Medicine. 2011; 57 (4): 355-356. DOI: 10.1016/j.annemergmed.2010.08.028. PMID: 20875692
Biros M, Sargent C, Miller K. Community Attitudes towards Emergency Research and Exception from Informed Consent. Resuscitation 2009; 80: 1382-1387. PMID:19818546
Biros MH, Baren JM. Commentary. The Ethics of Observation. Academic Emergency Medicine. 2009; 16 (9): 908-910. PMID: 19673706
Miner JR, Gray RO, Stephens D, Biros MH. Randomized Clinical Trial of Propofol With and Without Alfentanil for Deep Procedural Sedation in the Emergency Department. Academic Emergency Medicine. 2009; 16 (9): 825-834. PMID: 19845550
Miner JR, Moore J, Gray RO, Skinner L, Biros MH. Oral versus Intravenous Opioid Dosing for the Initial Treatment of Acute Musculoskeletal Pain in the Emergency Department. Academic Emergency Medicine. 2008; 16 (12): 1234-1240. PMID:18945240
Biros MH. The Ethics of Research in Emergency Medicine; Science and Engineering Ethics; Volume 13, No. 3, 2007; 279-280. PMID: 18210222
Biros MH. Research without Consent: Exception from and Waiver of Informed Consent in Resuscitation Research; Science and Engineering Ethics; 2007; 13(3): 361-369. PMID: 18210229
Baren J, Biros MH. Research on Community Consultation: An Annotated Bibliography.Academic Emergency Medicine 2007; 14 (4): 346-52. PMID: 17400998
Teaching
Teaching Areas
Emergency Medicine; Ethics and Informed Consent; Grief and Death Telling; Head Trauma and Neurological Emergencies
Courses
EMMD 7521, Research in Emergency Medicine - Course Director
Clinical
Specialties
- Emergency Medicine
Board Certifications
1988-2017 Emergency Medicine
Clinical Interests
Acute neuroscience, biomedical ethics