Piet de Groen, MD

Professor of Medicine, Division of Gastroenterology, Hepatology, and Nutrition

Piet de Groen

Contact Info

Mailing Address:
420 Delaware Street SE
MMC 36
Minneapolis, MN 55455

Lab Address:
505 Essex St SE
Diehl Hall 6th floor, room 612
Minneapolis, MN 55455

Administrative Assistant Name
Colleen Unger

Administrative Phone

Administrative Email

Administrative Fax Number

Professor of Medicine, Division of Gastroenterology, Hepatology, and Nutrition


Medical School, Catholic University Nijmegen, Nijmegen, The Netherlands

Residency, Mayo Clinic, Rochester, MN

Fellowship, Mayo Clinic, Rochester, MN

Fellowship, University of Utrecht, Utrecht, Netherlands


Dr. de Groen is a Professor of Medicine in the Division of Gastroenterology, Hepatology and Nutrition, at the University of Minnesota, emeritus staff at Mayo Clinic College of Medicine and former Program Director of the Mayo Clinic/IBM Computational Biology Collaboration. He is an NIH-funded clinical investigator and international expert in medical informatics, primary liver cancers and colonoscopy.

His endoscopic research is focused on measuring what happens during colonoscopy. Together with collaborators at Iowa State University and the University of North Texas he has created a first-of-a-kind new software system that automatically captures and analyzes “inside-the-patient” video information of medical procedures performed via endoscopy. At present he is studying patient- and endoscopist-specific features, including quality of the colon preparation and effort of the endoscopist to visualize mucosa, remove remaining fecal material and adequately distend the colon. Another focus of study is automated measurement of the degree of mucosal inflammation as seen in inflammatory bowel diseases.

The ultimate goal of his endoscopic research related to colonoscopy is a fully automated quality control system that provides real-time feedback to the endoscopist and ensures individualized healthcare by virtually guaranteeing a high quality examination for each patient. Another goal is to extend the technology to other organs examined using endoscopy equipment and combine the information obtained from the optical signal with information derived from other imaging modalities.

Professional Associations

  • Member, American College of Gastroenterology
  • Member, American Gastroenterological Association
  • Member, American Medical Information Association
  • Member, American Society for Gastrointestinal Endoscopy
  • Member, Association for the Study of Liver Diseases


Research Summary/Interests

  • Colorectal cancer prevention, colonoscopy and quality of endoscopy
  • Natural language processing
  • Fatty liver disease



Academic Interests and Focus

Endoscopy, comprehensive patient evaluation


Board Certifications

  • American Board of Internal Medicine
  • American Board of Internal Medicine, Gastroenterology

Clinical Interests

Colorectal cancer prevention, primary liver cancer, drug-induced liver toxicity, fatty liver disease