Sue Duval, PhD

Professor of Medicine, Cardiovascular Division

Sue Duval

Contact Info

Mailing Address:
420 Delaware Street SE
MMC 508 Mayo
8508A (Campus Delivery Code)
Minneapolis, MN 55455

Administrative Assistant Name
Roberta Beach

Administrative Email

PhD, University of Colorado Health Sciences Center, Denver, CO


"Methodology is the core of excellence in cardiovascular health investigation."

Professor Duval received her BSc (Honors) in Statistical Science from Flinders University of South Australia in 1993 and her PhD in Biostatistics from the University of Colorado Health Sciences Center in 1999. She has served on the faculty of the Division of Epidemiology and Community Health (University of Minnesota), and joined the Lillehei Clinical Research Unit of the Cardiovascular Division in 2011. Her career has been dedicated to the application of methodological approaches to cardiovascular clinical research.

Prof. Duval serves as a faculty statistician in the AHRQ-funded "Evidence-Based Practice Center (EPC)" at the University of Minnesota. She has achieved international recognition for the development of the "Trim and Fill" algorithm to address advanced issues in publication bias. Her papers on this topic in Biometrics and the Journal of the American Statistical Association have been cited over 6,800 times.

She has been recognized as a Fellow of the American Heart Association, and serves on the editorial board of Research Synthesis Methods, the official journal of the Society for Research Synthesis Methodology (SRSM). She is also a statistical editor for Circulation, the American Heart Association's flagship journal, and is the statistical consultant for the Vascular Medicine Journal

Awards & Recognition

  • University of Minnesota Medical School “Wall of Scholarship” Award* (2014 & 2018)
  • Fellow of the American Heart Association, Peripheral Vascular Disease Council (2012)
  • Invited inaugural member, Society for Research Synthesis Methodology (2006)
  • The Strother G. Walker Award for outstanding performance in the biometrics PhD program, University of Colorado Health Sciences Center (1998)

*Awarded to faculty with first or last author credits on a publication that has been cited at least 1,000 times as indicated by two of three major citation indices (Google Scholar, Scopus, Web of Science).


Research Summary/Interests

  • Evaluation of the efficacy, harm, and cost-effectiveness of cardiovascular disease; behavioral, pharmacologic, and device-based therapeutic interventions spanning coronary artery and peripheral artery disease (PAD) syndromes, heart failure, and other cardiovascular diseases
  • Epidemiology of cardiovascular diseases
  • Analysis of administrative databases and registries
  • Meta-analytic methods applied to cardiovascular clinical trials and observational studies


  1. Rocha-SinghKJ, DuvalS, Jaff MR, Schneider PA, Ansel GM, Lyden SP, Mullin CM, Ioannidis JPA, Misra S, Tzafriri AR, Edelman ER, Granada JF, White CJ, Beckman JA; VIVA Physicians. Mortality and paclitaxel-coated devices: An individual patient data meta-analysis. Circulation 2020 Jun 9;141(23):1859-1869. PMID: 32370548
  2. Duval S, Van't Hof JR, Steffen LM, Luepker RV. Estimation of cardiovascular risk from self-reported knowledge of risk factors: Insights from the Minnesota Heart Survey. Clin Epidemiol 2020 Jan 14;12:41-49. PMID: 32021470; PMCID: PMC6969684
  3. Rocha-Singh KJ, Duval S. Statistical alchemy and the road ahead. JACC Cardiovasc Interv 2019 Dec 23;12(24):2525-2527. PMID: 31857022
  4. Duval S, Pepe PE, Aufderheide TP, Goodloe JM, Debaty G, Labarère J, Sugiyama A, Yannopoulos D. Optimal combination of compression rate and depth during cardiopulmonary resuscitation for functionally-favorable survival. JAMA Cardiol 2019 Sep 1;4(9):900-908. PMID: 31411632; PMCID: PMC6694399
  5. Cohn JN, Duprez DA, Hoke L, Florea N, Duval S. Office blood pressure and cardiovascular disease: Pathophysiologic implications for diagnosis and treatment. Hypertension 2017 May; 69(5):e14-e20. PMID: 28348011
  6. Duval S, Long KH, Roy SS, Oldenburg NC, Harr K, Fee RM, Sharma RR, Alesci NL, Hirsch AT. The contribution of tobacco use to high healthcare utilization and medical costs in peripheral artery disease: A state-based cohort analysis. JACC 2015 Oct 6; 66(14):1566-1574. PMID: 26429081
  7. Prins KW, Neill JM, Tyler JO, Eckman PM, Duval S. Effects of beta-blocker withdrawal in acute decompensated heart failure: A systematic review and meta-analysis. JACC Heart Fail 2015 Aug; 3(8):647-653. PMID: 26251094
  8. Hirsch AT, Duval S. The global pandemic of peripheral artery disease. Lancet 2013 Oct 19; 382(9901):1312-1314. PMID: 23915884
  9. Duval S, Tweedie R. Trim and fill: A simple funnel plot-based method of testing and adjusting for publication bias in meta-analysis. Biometrics 2000 Jun; 56(2):455-463. PMID: 10877304
  10. Duval SJ, Tweedie RL. A non-parametric “Trim and Fill” method of accounting for publication bias in meta-analysis. J Am Stat Assoc 2000; 95(449):89-98.