Emmanuel S. Antonarakis, MD

Clark Endowed Professor of Medicine, Division of Hematology, Oncology and Transplantation

Emmanuel S. Antonarakis

Contact Info

Administrative Assistant Name
Heidi Goski

Administrative Phone
612-625-8287

Administrative Email
laws0067@umn.edu

Administrative Fax Number
612-625-6919

Clark Endowed Professor of Medicine, Division of Hematology, Oncology and Transplantation

Associate Director of Translational Research, Masonic Cancer Center


Genitourinary Oncologist


MD, University of Wales College of Medicine, Cardiff, UK

Residency, Johns Hopkins Bayview Medical Center, Baltimore, MD

Fellowship, Johns Hopkins Hospital, Baltimore, MD

Summary

I am a genitourinary medical oncologist with a particular focus on recurrent and advanced prostate cancer. I conduct clinical and translational studies to bring new therapies to patients with prostate cancer. In particular, I am interested in developing novel androgen-directed therapies, genetically-targeted therapies, and immunotherapies for men with recurrent or advanced prostate cancer, and using germline and tumor genomics to inform precision oncology approaches for these patients. I also have an interest in liquid biomarker development, including the clinical validation of the AR-V7 marker as well as DNA repair markers and their therapeutic implications. I am also involved in mentoring fellows and junior faculty in the clinical care of genitourinary cancers and the development of translational research strategies related to prostate cancer.

Expertise

  • Biomarker Development
  • Cancer immunotherapy
  • Clinical Trials
  • Genetics and Genomics
  • Liquid Biopsy in Cancer
  • Prostate Cancer Clinical and Translational Research

Awards & Recognition

  • Cardiff Medical Society Top Medical Student Prize, University of Wales College of Medicine (2003)
  • ASCO Young Investigator Award, American Society of Clinical Oncology (2009); PCF Young Investigator Award, Prostate Cancer Foundation (2013)
  •  AUA Young Investigator Award, American Urological Association (2015)
  •  Urology Teaching Award, Johns Hopkins Department of Urology (2017)
  •  Medical Oncology Teaching Award, Johns Hopkins Department of Oncology (2018)
  • PCF Challenge Award, Prostate Cancer Foundation (2019); Castle Connolly, Top Doctors (2012–2020)
  • U.S. News and World Report, Top Doctors (2012–2020)

Professional Associations

  • American Association for Cancer Research; American Society of Clinical Oncology
  • ASCO Educational Committee
  • European Society of Medical Oncology
  • International Society of Liquid Biopsy
  • National Comprehensive Cancer Network
  • NCI Prostate Cancer Task Force
  • Prostate Cancer Clinical Trials Consortium
  • Prostate Cancer Clinical Trials Working Group
  • Prostate Cancer Foundation
  • Society for Basic Urologic Research

Research

Research Summary/Interests

  • Prostate Cancer Clinical and Translational Research
  • Liquid Biopsy in Cancer
  • Genetics and Genomics
  • Cancer Immunotherapy
  • Androgen-Directed Therapies
  • Genetically-Targeted Therapies
  • Biomarker Development
  • Precision Oncology

Teaching

Academic Interests and Focus

Clinical Mentoring of Fellows and Junior Faculty on the Management of Prostate Cancer; Teaching on Translational Research Approaches; Teaching on Clinical Trial Design

Clinical

Clinical Interests

Genitourinary Medical Oncology; Recurrent and Advanced Prostate Cancer; Cancer Clinical Trials