Nathan Zaidman

Nathan Zaidman

Contact Info


Ph.D., Physiology, University of Minnesota, Department of Integrative Biology and Physiology, 2016

B.S., Biomedical Engineering, University of Minnesota, 2010


Nathan is currently a Post Doctoral Fellow in Jennifer Pluznick's lab, Johns Hopkins Medical School.

Summary

Dissertation Title: The Role of Hydrocortisone on the Development and Maintenance of Ion Transport Pathways Essential to Mucociliary Clearance in Differentiated Normal Human Bronchial Epithelial Cells

Advisors: Scott O'Grady, Ph.D, and Angela Panoskaltsis-Mortari, Ph.D.

Date of Final Defense: September 19, 2016

Awards & Recognition

  • Robert Gunn Student Award Finalist (2016)
  • Epithelial Transport Group Meritorious Research Travel Award (2016), Bacaner Research Award (2016)
  • Stem Cell Institute Travel Award (2015)
  • Lifson-Johnson Memorial Award (2013)
  • Alan Hemingway Scholarship (2012)

Research

Research Funding Grants

2014-PresentF31 EB018707-02 (Zaidman) 7/1/14 – 7/1/16

Ruth L. Kirschstein National Research Service Award

Engineering human iPS cells into an airway epithelium capable of ion transport. Role: Principal Investigator

Publications

1.Zaidman N, and Bosnakovski D. Advancing with Ceramic Biocomposites for Bone Graft Implants. Recent Pat Regen Medicine. 2012;2(1):65-72.

2.Gjorgieva D, Zaidman N, and Bosnakovski D. Mesenchymal stem cells for anti-cancer drug delivery. Recent Pat Anticancer Drug Discov. 2013;8(3):310-8.

3.Krishna VD, Roach E, Zaidman NA, Panoskaltsis-Mortari A, Rotschafer JH, O'Grady SM, and Cheeran MC. Differential Induction of Type I and Type III Interferons by Swine and Human Origin H1N1 Influenza A Viruses in Porcine Airway Epithelial Cells. PLoS One. 2015;10(9):e0138704.

4.Peitzman ER, Zaidman NA, Maniak PJ, and O'Grady SM. Agonist binding to beta-adrenergic receptors on human airway epithelial cells inhibits migration and wound repair. Am J Physiol Cell Physiol. 2015;309(12):C847-55.

5.Peitzman ER, Zaidman NA, Maniak PJ, and O'Grady SM. Carvedilol binding to beta2-adrenergic receptors inhibits CFTR-dependent anion secretion in airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2016;310(1):L50-8.

6.Zaidman NA, Panoskaltsis-Mortari A, and O'Grady SM. Differentiation of human bronchial epithelial cells: Role of hydrocortisone in development of ion transport pathways involved in mucociliary clearance. Am J Physiol Cell Physiol ajpcell 00073 02016, 2016.*APSselect August, 2016.

7.Zaidman NA, Panoskaltsis-Mortari A, and O'Grady SM. Large Conductance Ca2+-activated K+ Channel Activation by Purinergic Receptor Agonists Requires Hydrocortisone in Differentiated Normal Human Bronchial Epithelial Cells. In Prep. Expected Submission, 2016.

8.Zaidman NA, Panoskaltsis-Mortari A, and O'Grady SM. Regulation of Claudin Expression and Paracellular Ion Transport by Glucocorticoids in Differentiated Human Bronchial Epithelial Cells. In Prep. Expected Submission, 2016.

9.Cero C, Razzoli M, Han R, Gurney A, Guo ZengKui, Zaidman NA, Miles JM, O’Grady SM and Bartolomucci A.TLQP-21 enhances ?AR-induced lipolysis via Ca2+ mobilization and ERK phosphorylation and exerts an anti-obesity effect.In review, 2016.

10.Srisomboon Y, Zaidman NA, Maniak PJ, Deachapunya C and O’Grady SM.Potassium secretion by human mammary epithelial cells involves K2P channels that are regulated by P2Y receptor agonists.In review, J Physiol, 2016.

11.Zaidman NA, O’Grady KE, Patil N, Maniak PJ, Milavetz F, Kita H and O’Grady SM.Airway epithelial anion secretion and barrier function following exposure to fungal aeroallergens: Role of oxidative stress.In Prep. Expected Submission, 2016.