Chastity L. Healy

Researcher 3, Department of Integrative Biology and Physiology (IBP)

Chastity L. Healy

Contact Info

Office Phone 612-626-5585

BS, Biology, University of South Dakota



  • Henpita C1, Healy C.L.1, Vyas R., Kieu T., Gurkar A.U., Vanderpool R.R., Lu A, Cui Y., Yousefzadeh M.J., Angelini L.A., O’Kelly R.D., McGowan S.J., Chandrasekhar S., Hennessy-Wack D., Ross M.A., Bachman TN, McTiernan C., Wang Y., Huard J., Beer-Stolz D., St Croix C.M., Watkins S.C., Pillai S.P.S., Ladiges W., Gorcsan III J., Robbins P.D., Kelley E.E., Mora A.L., O’Connell T.D.*, and Niedernhofer L.J.*Loss of DNA repair mechanisms in cardiac myocytes induces dilated cardiomyopathy. 2022. Aging Cell. Under review. 1Co-first authors
  • Egbert J.R., Uliasz T.F., Lowther K.M., Kaback D., Wagner B.M., Healy C.L., O’Connell T.D., Potter L.R., Jaffe L.A.*, and Yee S-P.* Epitope tag and phosphomimetic mouse models for investigating natriuretic peptide-stimulated receptor guanylyl cyclases. 2022. Frontiers in Physiology. Under review.
  • Zhang N., Murphy K.A., Harcsh B.A, Zhang M.J., Gyberg D.J., Stevens J.A., Wagner B.M., Mendelson J., Patterson M.T., Orchard D.A., Healy C.L., Williams J.W., Townsend D., Shearer G.S., and O’Connell T.D. FFAR4 regulates cardiac oxylipin balance to promote inflammation resolution in HFpEF secondary to metabolic syndrome. 2022. Cardiovascular Research. Under review.
  • Zhang N, Murphy K.A., Harsch B.A., Zhang M., Gyberg D., Mendhelson J., Healy C.L., Shearer G.S., and O’Connell T.D.Signaling through free fatty acid receptor 4 attenuates cardiometabolic disease. Physiology. 2022. PMID 35944007
  • Wagner B.M., Robinson J.W., Healy C.L., Gauthier M., Dickey D.M., Yee S.P., Osborn J.W., O’Connell T.D.*, and Potter L.R.* Guanylyl cyclase-A phosphorylation decreases cardiac hypertrophy and improves systolic function in male, but not female, mice. 2022.FASEB J. 36(1): e22069
  • Zhang M.J.2, Karachenets S3, Healy C.L., and O’Connell T.D.* Myocardial ischemia reperfusion without endotracheal intubation or ventilation. J Amer Coll Cardiol. Basic Trans Sci. 20216(7):624-626.
  • Murphy K.A.2, Harsch B.A.1, Healy C.L., Joshi, S.S.2, Huang, S., Walker, R.E., Wagner, B.M.1, Ernste, K.M.3, Huang, W. Block, R.C., Wright, C.D., Tintle, N., Jensen, B.C., Wells, Q.S., Shearer, G.C.*, and O’Connell, T.D.* Free fatty acid receptor 4 responds to endogenous fatty acids to protect the heart from pressure overload. Cardiovasc Research. 2021 Mar 22:cvab111
  • Dahl EF, Wu SC, Healy CL, Perry J, O'Connell TD. ERK mediated survival signaling is dependent on the Gq-G-protein coupled receptor type and subcellular localization in adult cardiac myocytes. J Mol Cell Cardiol 2018. PMID 30528765