Jin O-Uchi, MD, PhD, FAHA, FCVS

Jin O-Uchi MD, PhD is Assistant Professor of Medicine at the Lillehei Heart Institute, Department of Medicine, Cardiology Division at the University of Minnesota.

Dr. O-Uchi received the MD and PhD degree from Jikei University School of Medicine in Japan. He did a postdoctoral fellowship at University of Rochester and worked as an Instructor and a Research Assistant Professor at Thomas Jefferson University. Prior to his position with the U of MN, , he was at Cardiovascular Research Center at Brown University and Rhode island Hospital as an Assistant Professor of Medicine. His research potential has been recognized at a national level by grant awards from NIH/NHLBI, NIH/NIGMS, American Heart Association (AHA) and American Physiological Society (APS). He serves on several editorial boards for publications including Frontiers in Physiology; Frontiers in Cardiovascular Medicine; Frontiers in Genetics; Frontiers in Cell and Developmental Biology; World Journal of Cardiology; Journal of Biochemistry and Molecular Biology Research; and JSM Biochemistry and Molecular Biology. Dr. O-Uchi is a Fellow of Cardiovascular Section of American Physiological Society (FCVS), and a Trustee (elected) of Japanese Physiological Society (JPS). He is a member of the and the American Heart Association (AHA), International Society for Heart Research (ISHR), American Physiological Society (APS), Biophysical Society (BPS), and Cardiac Muscle Society, among others. His research interests include cardiac excitation-contarction/metabolism coupling, heart failure, sudden cardiac death, cardiac channelopathies, and cardiac mitochondrial biology.

• Selected Speaker for “Featured Topic Session” at Experimental Biology Meeting (2019)
• Fellow of American Heart Association, American Heart Association Basic Cardiovascular Sciences (2018)
• Finalist, Neonatal Cardiopulmonary Biology Young Investigator Award (2018)
• Fellow of Cardiovascular Section of American Physiological Society (2018)
• Shih-Chun Wang Young Investigator Award, American Physiological Society (2017)
• Oral Abstract Award, Central Society for Clinical and Translational Research (2017)
• Finalist, Gary Lopaschuk Young Faculty Award, International Academy of Cardiovascular Sciences (2016)
• New investigator Award, American Physiological Society, Cell and Molecular Physiology Section (2015)
• Early Career Investigator Travel Awards, International Society for Heart Research (2013)
• Research Career Enhancement Award, American Physiological Society (2013)
• Finalist, Outstanding Early Career Investigator Award AHA, Basic Cardiovascular Sciences (2012)
• Hiroshi and Aya Irisawa Memorial Promotion Award Physiological Society of Japan for Young Scientists (2011)
• Richard J. Bing Award, International Society for Heart Research, (2012)
• Postdoctoral Fellowship Award, American Heart Association (2009)
• Promotion Award, Physiological Society of Japan (2009)
• Foreign study Award, Kanae Foundation, Tokyo Japan (2008)
• Graduate Student Best Paper Award, Jikei University School of Medicine (2007)
• Research Grant Award, Jikei University School of Medicine (2007)
• Medical Science Research Award, Kato Memorial Bioscience Foundation (2007)
• Trustee (elected) of Physiological Society of Japan (2006)
• Young Investigator Award, International Academy of Cardiovascular Sciences, Japan Section (2006)
• Young Investigator's Research Award, Japan Heart Foundation (2006)
• Fellowship Award, Japan Foundation of Cardiovascular Research (2006)
• Travel Grant Award, Inoue Foundation for Science (2006)
• Travel Grant Award, Kato Memorial Bioscience Foundation (2006)
• Best Oral Presentation Award, International Society for Heart Research, Japanese Section (2005)
• Travel Grant Award, The Naito Foundation (2005)
• Young Investigator's Travel Grant Award, Jikei Alumni Association (2005)
• Graduate Student's Research Award, Jikei University School of Medicine (2005)

• Member of Career Opportunities in Physiology Committee, American Physiological Society, Cardiovascular Section (2020-present)
• Ad-hoc Peer Grant Reviewer, Medical Research Council UK Research and Innovation (2019-present)
• Member of Awards Selection Committee, American Physiological Society, Cardiovascular Section (2018-present)
• Member of Peer Grant Review Committee, American Heart Association (2018-present)
• Trustee (elected) of Physiological Society of Japan (2006-present)
• Heart Rhythm Society
• Central Society for Clinical and Translational Research (CSCTR)
• American Heart Association (AHA)
• International Society for Heart Research (ISHR)
• Society of Cardiovascular Anesthesiologists (SCA)
• International Academy of Cardiovascular Sciences (IACS)
• Cardiac Muscle Society
• American Physiological Society (APS)
• Society of General Physiologist (SGP)
• Biophysical Society (BPS)

• Arrhythmia
• Heart Failure
• Adrenergic Signaling
• Ion Channels
• Mitochondria

A complete list of publication can be found at NCBI

• O-Uchi J*#, Jhun BS*#, Adaniya SM, Mancini TJ, Landi AK, Cao JL, Xu X, Yoon Y, Choudhary G, Clements RT, Mende U, Sheu SS. Protein kinase D activation induces mitochondrial fragmentation and dysfunction in cardiomyocytes. J Physiol. 596(5):827-855, 2018. PMID: 29313986 (#Equal contribution) *Corresponding authors. [Cover Image]
• O-Uchi J*, Ryu SY, Jhun BS, Hurst S, Sheu SS. Mitochondrial Ion Channels/Transporters as Sensors and Regulators of Cellular Redox Signaling. Antioxid Redox Signal. 21(6):987-1006, 2014. PMID: 24180309. *Corresponding author.
• O-Uchi, J*, Jons, C*, Moss, AJ, Reumann, M, Rice, JJ., Goldenberg, I, Zareba, W, Wilde, AA, Shimizu, W, Kanters, JK, McNitt, S, Hofman, N, Robinson, JL, Lopes, CMB. (*Equal contribution).Use of Mutant-Specific Ion Channel Characteristics for Risk Stratification of Long QT Syndrome Patients. Science Translational Medicine. (2011)3(76):76ra28, 2011. [Cover Image] PMID: 21451124
•  O-Uchi J*, Sasaki H, Morimoto S, Kusakari Y, Shinji H, Obata T, Hongo K, Komukai K, Kurihara S. Interaction of ?1-adrenoceptor subtypes with different G proteins induces opposite effects on cardiac L-type Ca2+ channel. Circ Res. 102:1378-1388, 2008.PMID: 18467629 *Corresponding author.
• O-Uchi J*, Komukai K, Kusakari Y, Obata T, Hongo K, Sasaki H, Kurihara S. ?1-Adrenoceptor stimulation potentiates L-type Ca2+ current through Ca2+/calmodulin-dependent PK II (CaMKII) activation in rat ventricular myocytes. Proc Natl Acad Sci U S A. 102(26):9400-9405, 2005. PMID: 15964981 *Corresponding author