Steven C. Wu, PhD
Assistant Professor, Department of Integrative Biology and Physiology (IBP)
Contact Info
Assistant Professor, Department of Integrative Biology and Physiology (IBP)
PhD, University of Illinois at Chicago (Physiology & Biophysics),
BS, Colorado State University (Biochemistry),
Research
Research Summary/Interests
Novel mechanisms regulating cardiac myocyte contractility and survival in the heart.
Publications
- EPA, not DHA, prevents fibrosis in pressure overload-induced heart failure: potential role of free fatty acid receptor 4. Eclov JA, Qian Q, Redetzke R, Chen Q, Wu SC, Healy CL, Ortmeier SB, Harmon E, Shearer GC, O'Connell TD. J Lipid Res. 2015 Dec;56(12):2297-308. doi: 10.1194/jlr.M062034. Epub 2015 Oct 4.
- A nuclear option? G-protein coupled receptors at the nucleus in cardiac myocytes. Wu SC, O?Connell TD. J Cardiovasc Pharmacol. 2015 Feb;65(2):89-90. doi: 10.1097/FJC.0000000000000205.
- Derivation and high engraftment of patient-specific cardiomyocyte sheet using induced pluripotent stem cells generated from adult cardiac fibroblast. Zhang L, Guo J, Zhang P, Xiong Q, Wu SC, Xia L, Roy SS, Tolar J, O'Connell TD, Kyba M, Liao K, Zhang J. Circ Heart Fail. 2015 Jan;8(1):156-66. doi: 10.1161/CIRCHEARTFAILURE.114.001317. Epub 2014 Nov 24.
- Nuclear compartmentalization of ?1-adrenergic receptor signaling in adult cardiac myocytes. Wu SC, O?Connell TD. J Cardiovasc Pharmacol. 2015 Feb;65(2):91-100. doi: 10.1097/FJC.0000000000000165. Review.
- Nuclear localization of a1A-adrenergic receptors is required for signaling in cardiac myocytes: an “inside-out” a1-AR signaling pathway. Wu SC, Dahl EF, Wright CD, Cypher AL, Healy CL, O'Connell TD. J Am Heart Assoc. 2014;3(2):e000145.
- Nuclear localization drives ?1-adrenergic receptor oligomerization and signaling in cardiac myocytes. Wright CD, Wu SC, Dahl EF, Sazama AJ, O'Connell TD. Cell Signal. 2012 Mar;24(3):794-802. doi: 10.1016/j.cellsig.2011.11.014. Epub 2011 Nov 18.