Leslie Morse



Dr. Leslie Morse obtained her Doctor of Osteopathic Medicine degree from the University of New England College of Osteopathic Medicine followed by her residency in Physical Medicine and Rehabilitation at Boston Medical Center. She is board certified by the American Board of Physical Medicine and Rehabilitation. Dr. Morse continues to work on local and national level to promote the field of rehabilitation medicine. 


Therapeutic outcome analysis, stem cell therapy for spinal cord injury, osteoclast biology, gait training and analysis

Awards & Recognition

  • 2020 American Paraplegia Society Excellence Award, Academy of Spinal Cord Injury Professionals (ASCIP)
  • 2021 Rebecca “Becky” J. Adcock, PhD Award for Excellence in Mentoring, Academy of Spinal Cord Injury Professionals (ASCIP)

Professional Associations

  • Member, Research Committee Member, Association of Academic Physiatrists
  • International Society for Clinical Densitometry

Research Summary

Research Summary/Interests

Dr. Morse's research interests include the impact of mechanical unloading on bone metabolism and the development of novel stem cell therapies for motor recovery after SCI. 

Research Funding Grants

  • Department of Defense
    Role: Co-investigator
    2018 - 2022
    Assistive Technology and Functional Outcomes following Spinal Cord Injury (Monden PI) 
    The aims of this study are to: (1) examine perceived barriers to or facilitators of assistive technology (AT) access and utilization and the impact on functional and psychosocial outcomes after tetraplegia, (2) assess for variations in use of AT across insurance providers and socioeconomic status in Veterans and civilians with tetraplegia, (3) assess the relationship between AT use and productivity (employment/school), and (4) assess the relationship between AT and psychosocial outcomes.
  • NIDILRR, Department of Health and Human Services
    Role: Co-Project Director
    2016 - 2022
    Rocky Mountain Regional Spinal Injury System 
    The goals of this project are to (1) harness our existing multidisciplinary system of rehabilitation care designed specifically to meet the needs of individuals with SCI to extend the Model Systems knowledge base, (2) contribute to improving long term SCI outcomes through participation in site-specific and collaborative clinical trials and research projects, (3) contribute to the SCI model systems national database through longitudinal assessment of long term SCI outcomes, (4) Contribute to improved long term SCI outcomes by conducting a research project designed to reduce sublesional neuropathic pain following SCI.
  • NIDILRR, Department of Health and Human Services
    H133A150065 (Nash PI)
    Role: Co-investigator
    2016 - 2021
    Lifestyle intervention targeting enhanced health and function for persons with chronic SCI in caregiver/care-receiver relationships: effects of caregiver co-treatment
    The goals of this project are to: 1) determine the efficacy of a lifestyle intervention to improve health and function of individuals with SCI.
  • Department of Defense
    Role: PI
    2015 - 2022
    Effects of Ekso-assisted gait training on Bone Health and Quality of Life: A Randomized Clinical Trial
    The goals of this project are to 1) determine whether exoskeleton-assisted gait training increases bone strength in the paralyzed lower extremity and 2) determine whether exoskeleton-assisted gait training improves quality of life after SCI. Secondarily, to determine whether gait training improves the following related outcomes and mediators of quality of life: mood, pain, and cortical activity of related emotional networks in the brain.
    R01 AR064793-01A1 (Battaglino PI)
    Role: Co-investigator
    2015 - 2022
    Regulation of gastric and osteoclast acidification by Snx10
    The specific aims to be addressed in this project are: 1) Determine the cellular mechanisms by which Snx10 regulates osteoclast function. 2) Determine the role of osteoclastic expression of Snx10 on bone homeostasis in vivo. 3) Determine the whole of gastric expression of Snx10 on bone homeostasis in vivo.

Clinical Summary

Board Certifications

Physical Medicine and Rehabilitation (ABPMR)




500E Boynton
420 Delaware St SE
Minneapolis, MN 55455-0341