Sayak Ghatak, MBBS, PhD

Resident, Department of Laboratory Medicine and Pathology

Sayak Ghatak

Contact Info

MD, MBBS, Calcutta National Medical College, Kolkata, India, 2007

Research Fellow, Gastroenterology and Hepatology, Mayo Clinic, Rochester, 2018-2019

PhD, Biology, University of Rochester, 2014

MS, Biology, University of Rochester, 2010

Postdoctoral Associate, Department of Surgery, University of Rochester Medical Center 2015-2017

Summary

Sayak attended medical school in Calcutta, India, and soon after joined PhD program in Biology at the University of Rochester, where his doctoral thesis focused on the role of bile acids in the molecular pathogenesis of GERD and Barrett’s Esophagus. He continued his research interests in gastrointestinal carcinogenesis, tissue engineering and gastrointestinal motility through his next few post-doctoral positions at the University of Rochester and the Mayo Clinic, Rochester. Currently, he is pursuing Anatomic Pathology residency program at the UMN. Through clinical training and research support at the program, he hopes to advance his career as a physician researcher dedicated to understanding the molecular dynamics of carcinogenesis.

Sayak is also an amateur musician, and loves to spend time with his wife playing VR games, cooking, camping and travelling.

Awards & Recognition

Best Poster Award (fellow category)- USCAP, National Harbor 2019

Poster of Distinction (top 10% of SSAT abstracts)- Digestive Disease Week, Chicago 2017

Research

Publications

M. A. Khalifa, M. Atri, M. E. Klein, S. Ghatak, P. Murugan.  Adenomyosis as a Confounder to Accurate Endometrial Cancer Staging.Seminars in Ultrasound, CT and MRI, Volume 40, Issue 4, Pages 358-363 (August 2019)

S. Ghatak, M. Reveiller, L. Toia, A. Ivanov, Z. Zhou, E. M. Redmond, T. E. Godfrey, and J. H. Peters. Bile acid at low pH causes dilation of intercellular spaces in in vitro stratified primary esophageal cells possibly by modulating Wnt signaling. Journal of Gastrointestinal Surgery, Volume 20, Issue 3, pp 500-5 (2016)

S. Ghatak, M. Reveiller, L. Toia, A. Ivanov, T. E. Godfrey, and J. H. Peters. Bile Acid at Low pH Reduces Squamous Differentiation and Activates EGFR Signaling in Esophageal Squamous Cells in 3-D Culture. Journal of Gastrointestinal Surgery 17, 1723 (2013)

M. Reveiller, S. Ghatak, L. Toia, I. Kalatskaya, L. Stein, M. D'Souza, Z. Zhou, S. Bandla, W. E. Gooding, T. E. Godfrey and J.H. Peters.  Bile exposure inhibits expression of squamous differentiation genes in human esophageal epithelial cells.  Annals of surgery 255, 1113 (2012)