James Moller, MD, FACC

Professor Emeritus of Pediatrics and Medicine (Joint Appointment), Department of Pediatrics

James Moller

Contact Info

Fax 612-626-2467

Office Address:
Cardiovascular Division
Variety Club Research Center
401 East River Parkway
2nd Floor
Minneapolis, Minnesota 55455

Mailing Address:
UMN – Cardiovascular Division
420 Delaware Street SE
MMC 508 Mayo
8508A (Campus Delivery Code)
Minneapolis, MN 55455

Administrative Assistant Name

Administrative Email

Professor Emeritus of Pediatrics and Medicine (Joint Appointment), Department of Pediatrics

Pediatric Cardiologist

Medical School, Stanford Hospital, San Francisco, CA (1958)

Pediatric Residency, University of Minnesota, Minneapolis, MN (1963-65)

Pediatric Cardiology Fellowship, University of Minnesota, Minneapolis, MN (1956-61)

Internship in Medicine, Stanford University Hospital,San Francisco, CA (1958-59)


I have been at the University of Minnesota since 1959, for many years in the Department of Pediatrics and for the last five years in the Department of Medicine. I served a chief of Staff of the University of Minnesota Hospital for five years and as Head of the Department of Pediatrics for seven years. My primary interest is congenital heart disease in both children and adults. For thirty years, I held the Paul F. Dwan Chair in Pediatric Cardiology. Currently I see patients on an out-patient basis. Weekly, I review with small groups of students and residents specimens of cardiac malformations. Writing and editing books has been an ongoing activity for me.


  • Clinical diagnosis of congenital heart disease
  • Applying a pathophysiological approach to understanding congenital heart disease

Awards & Recognition

  • President of the American Heart Association, 1993-94.
  • 2011 Eugene Braunwald Academic Mentorship Award of American Heart Association
  • Founder’s Award, Section of Cardiology, American Academy of Pediatrics, 2011
  • Harold Diehl Award, University of Minnesota Medical Alumni Association, 2011


Research Summary/Interests

I have had four primary areas of research during my career at the University of Minnesota.

  1. Exercise physiology of cardiac malformations. This involved studying children during cardiac catheterization with specific anomalies. We performed various measurements at both resting and during six minute exercise using a bicycle ergometer. We assessed the changes which occurred with exercise and compared the data to normal exercise responses.
  2. Long-term follow-up of patients with congenital heart disease. Since the first operations of children with congenital heart disease were performed, I have had a unique opportunity to assess the status of these patients after a number of years, now over 60 years in some instances. We have followed about 1,500 patients by correspondence or telephone in our studies, including one with 99.2% follow-up of 1,000 patients at 50 years.
  3. Cardiac pathology. During my fellowship, I spent one year with Dr. Jesse E. Edwards, a renowned cardiac pathologist and another year as a Research Associate. Subsequently, I worked with him on many occasions studying specimens of congenital anomalies. I have maintained that interest to the present and do some work in the Edwards Registry of Cardiovascular Diseases.
  4. Pediatric Cardiac Care Consortium. I created and directed the Consortium for 27 years. The purpose of the Consortium was to assess the care and outcomes of cardiac operations and interventional techniques in children with congenital or acquired cardiac disease. We recruited cardiac centers to participate in the program and eventually had 52 centers involved. The centers submitted to our office defined information on each patient undergoing a cardiac catheterization or cardiac operations they performed. Annually, we prepared reports for each center statistically comparing their experience and results to the group of centers. Over the 27 years, we obtained data on 135,000 children, which represented the largest data base in the US. Over the 27 years, the operative mortality rates decreased for each category of cardiac anomaly and centers used the data to improve their outcomes.


18 books and 230 papers, including,

  • Moller JH, Hoffman JIE (Eds):Pediatric Cardiovascular Medicine, Second Edition. Wiley-Blackwell, Chichester, UK. 2011. 1076 pp.
  • Edwards BS, Moller JH: Jesse E. Edwards: His Legacy in Cardiovascular Medicine. Science International Corp. Stamford, CT. 2011. 381 pp.
  • Johnson WH, Moller JH: Pediatric Cardiology. The Essential Pocket Guide. Third Edition. Wiley-Blackwell, Chichester, UK. 2014. 392pp.



  • Adults with congenital heart disease, Pediatric cardiology


Clinics and Surgery Center

Board Certifications

Pediatric Cardiology

Clinical Interests

Diagnosing congenital heart disease

Clinical Experience Statement

I saw children with congenital heart disease beginning in 1960 and continued until 2011 and then I cared for adults cardiac anomalies until 2018. In my practice I relied on clinical skills and used diagnostic techniques, such as echocardiography, sparingly. Probably this was from the fact that I had practiced for over 50 years. I enjoyed teaching patients about their cardiac condition and its management. I believe that I was compassionate, listened carefully to patients and was interested in th