Snigdha Pusalavidyasagar (Sagar), MD

Associate Professor of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine

Snigdha Pusalavidyasagar (Sagar)

Contact Info

Mailing Address:
Division of Pulmonary, Allergy, Critical Care and Sleep Medicine
420 Delaware Street SE
MMC 276 (Pulmonary)
MMC 434 (Allergy)
Minneapolis, MN 55455

Administrative Assistant Name
Emily Olmsted-Morales

Administrative Phone

Administrative Email

Administrative Fax Number

Associate Professor of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine

Sleep Medicine/Internal Medicine (also at Hutchenson, MN)

Medical School, Osmania Medical College, Hyderbad, India

Internal Medicine Residency, Howard University Hospital, Washington, DC

Sleep Medicine Fellowship, Mayo Clinic, Rochester, MN


After receiving my medical degree, I completed my residency in Internal medicine in 2000. During my residency at Howard University, I was exposed to biomedical research and I became interested in pursuing clinical research for a career. However, for immigration reasons, I took a primary care position in a medically underserved rural area for a few years. From there, I became a research fellow in cardiovascular physiology at the Mayo Clinic. After spending two years doing clinical research, I completed a fellowship at the Mayo Clinic in sleep medicine and began to publish research reports. Subsequently, I then took a faculty position at the University of Minnesota in the Division of Pulmonary/Critical Care/Sleep Medicine. Meanwhile, I have continued to collaborate with Dr. Virend Somers at Mayo Clinic. Sleep medicine is a developing field, with ample opportunity for clinical research. Though obstructive sleep apnea’s (OSA) significant association with cardiovascular disease is well known, the pathophysiological mechanisms involved remain unclear. My plan is to pursue new biomarkers and other clinical indicators than will permit these pathophysiological mechanisms to become clearer. My aim is then to initiate a clinical research program that will use these biomarkers for early detection and, eventually, treatment of OSA.

Professional Associations

  • Primary Care Physician at Southern Metro Medical Clinics (Internal Medicine) - Le Seuer, MN
  • Research at Mayo Clinic (Caridovascular Physiology) - Rochester, MN
  • Supplemental Consultant at General Clinical Research Center (Internal Medicine) - Mayo Clinic, Rochester, MN
  • Assistant Professor of Medicine at Division of Pulmonary/Critical Care/Sleep Medicine (Sleep Medicine) - University of Minnesota Medical Center - Fairview, Minneapolis, MN
  • Fellow of American Academy of Sleep Medicine


Research Summary/Interests

Study pertaining to effects of changes in body fat composition on sleep and cardiovascular physiology (Mentor: Somers VK, MD); Study involving the relationship between sleep and acute myocardial infarction (Mentor: Somers VK, MD); Comparative analysis of cardiac inflammatory markers in Asian Indians vs. Caucasians (Mentor: Somers VK, MD)

Minnesota Medical Foundation Pusalavidyasagar (PI) 03/01/12-2/28/14
Determination of Endogenous Levels of Hydrogen Sulfide and Nitric Oxide in patients with Obstructive Sleep Apnea
Role: PI




  • Sleep medicine
  • Clinical research
  • Complimentary medicine and sleep disorders

Board Certifications

  • American Board of Internal Medicine
  • American Board of Sleep Medicine