Shanie A.L. Jayasinghe, PhD

Assistant Professor, Department of Rehabilitation Medicine

PhD, Biomedical Engineering, University of Southern California, Los Angeles

MS, Biomedical Engineering, University of Southern California, Los Angeles

BS, Biomedical Engineering, Georgia Institute of Technology, Atlanta

Graduate Certificate in Health, Technology & Engineering, University of Southern California, Los Angeles

Summary

Dr. Jayasinghe is a tenure-track assistant professor in the Divisions of Physical Therapy & Rehabilitation Science. She received her BS in Biomedical Engineering from Georgia Institute of Technology. She then attended the University of Southern California where she received both her MS and PhD in Biomedical Engineering. Dr. Jayasinghe completed postdoctoral training at Pennsylvania State University’s College of Medicine prior to joining the U of M.

Dr. Jayasinghe uses her engineering foundation to study clinically relevant questions related to upper limb movement. She is specifically interested in exploring the role of cognition in sensorimotor control in chronic stroke survivors.

Professional Associations

  • Society for Neuroscience
  • Society for the Neural Control of Movement
  • American Society of Neurorehabilitation

Research

Research Summary/Interests

Dr. Jayasinghe’s research interests are in motor neuroscience and neurorehabilitation, specifically in examining mechanisms of upper limb motor control to develop non-invasive and personalized tools for stroke rehabilitation. Currently, she is focused on understanding the role of lateralized motor and cognitive processes during movement, and how they influence functional outcomes in chronic stroke survivors with hemiparesis.

Research Funding Grants

  1. Medical School/UMF Assistant Professor Award, University of Minnesota: Aug. 2022-July 2023
  2. National Institute of Child Health and Human Development (R01 HD059783) 2019-2022. Title: Predicting ipsilesional motor deficits in stroke with dynamic dominance model. Role: Postdoctoral Scholar (MPI: Sainburg, Winstein). 

Publications

1. Maenza, C., Sainburg, R. L., Varghese, R., Dexheimer, B., Demers, M., Bishop, L., Jayasinghe, S. A. L., Wagstaff, D. A., & Winstein, C. for the IPSI Investigative Team (in-press) Ipsilesional arm training in severe stroke to improve functional independence (IPSI): Phase II protocol. BMC Neurology.

2. Jayasinghe, S. A. L., Scheidt, R. A., & Sainburg, R. L. (2022) Neural control of stopping and stabilizing the arm. Frontiers in Integrative Neuroscience, 16, 835852.

3. Jayasinghe, S. A. L., Maenza, C., Good, D. A., & Sainburg, R. L. (2021) Deficits in performance on a mechanically coupled asymmetrical bilateral task in chronic stroke survivors with mild unilateral paresis. Symmetry, 13(8), 1366.

4. Jayasinghe, S. A. L., Wang, R., Gebara, R., Biswas, S., & Ranganathan, R. (2021) Compensatory trunk movements in naturalistic reaching and manipulation tasks in chronic stroke survivors. Journal of Applied Biomechanics, 37(3), 215-223.

5. Jayasinghe, S. A. L., Sarlegna, F. R., Scheidt, R. A., & Sainburg, R. L. (2021) Somatosensory deafferentation reveals lateralized roles of proprioception in feedback and adaptive feedforward control of movement and posture. Current Opinion in Physiology, 19, 141-147.

6. Jayasinghe, S. A. L., & Ranganathan, R. (2021) Effects of short-term mental imagery and supplemental visual feedback on muscle coordination in a myoelectric task. Journal of Motor Behavior, 53(1), 59-71.

7. Jayasinghe, S. A. L., Good, D., Wagstaff, D. A., Winstein, C., & Sainburg, R. L. (2020) Motor deficits in the ipsilesional arm of severely paretic stroke survivors correlate with functional independence in left, but not right hemisphere damage. Frontiers in Human Neuroscience, 14, 539.

8. Jayasinghe, S. A. L., Sarlegna, F. R., Scheidt, R. A., & Sainburg, R. L. (2020) The neural foundations of handedness: Insights from a rare case of deafferentation. Journal of Neurophysiology, 124(1), 259-267.

9. Lee, M-H., & Jayasinghe, S. A. L. (2020) Self-controlled practice and nudging during structural learning of a novel control interface. PLoS ONE, 15(4), e0223810.

10. Jayasinghe, S. A. L. (2019). The role of sensory stimulation on motor learning via action observation: a mini review. Journal of Neurophysiology, 121(3), 729-731.

11. Liyanagamage (Jayasinghe), S. A., Bertucco, M., Bhanpuri, N. H., & Sanger, T. D. (2017). Scaled vibratory feedback can bias muscle use in children with dystonia during a redundant, 1-dimensional myocontrol task. Journal of Child Neurology, 32(2), 161-169.

Academic Conferences:

Jayasinghe, S.A.L., Maenza, C., Good, D., & Sainburg, R.L. Deficits in performance on a mechanically coupled bilateral task in chronic stroke survivors with mild unilateral paresis. Virtual poster presentation at the annual meeting of the Society for Neuroscience; 2021 Nov 8-11.

Dexheimer, B., Sandberg, C.W., Selby, K., Jayasinghe, S.A.L., Kantak, S.S., & Sainburg, R.L. Anodal (excitatory) HD-tDCS dissociates a role of the left posterior parietal cortex in motor adaptation. Virtual poster presentation at the annual meeting of the Society for Neuroscience; 2021 Nov 8-11.

Jayasinghe, S.A.L., Maenza, C., Good, D., & Sainburg, R.L. Specialized roles of each hand during a mechanically coupled bilateral task in patients with mild hemiparesis and age-matched typical adults. Virtual poster presentation at the annual meeting of the American Society of Neurorehabilitation; 2021 Apr 5-9.

Jayasinghe, S.A.L., Schaffer, J.E., Maenza, C., Sarlegna, F.R., Scheidt, R.A., & Sainburg, R.L. Large-fiber sensory neuropathy produces asymmetrical deficits in limb movement and stabilization: in the absence of vision, the dominant arm drifts, while the non-dominant arm does not. Poster at the annual meeting of the Society for Neuroscience; 2019 Oct 19-23; Chicago, IL.

Schaffer, J.E., Jayasinghe, S.A.L., Maenza, C., Sarlegna, F.R., & Sainburg, R.L. Somatosensory deafferentation produces deficits in predictive control of bilateral upper limb coordination and asymmetries in postural stabilization. Poster at the annual meeting of the Society for Neuroscience; 2019 Oct 19-23; Chicago, IL.

Jayasinghe, S.A.L., Maenza, C., Good, D., Winstein, C., & Sainburg, R.L. Kinematic measures of ipsilesional arm motor performance significantly predict both functional movement deficits and overall functional independence in moderate-to-severely impaired chronic stroke survivors. Poster at the annual meeting of the American Society of Neurorehabilitation; 2019 Oct 16-18; Chicago, IL.

Jayasinghe, S.L., & Ranganathan, R. Mental imagery as a tool to change muscle coordination patterns in chronic stroke survivors. Poster at the annual meeting of the Society for Neuroscience; 2018 Nov 3-7; San Diego, CA.

Jayasinghe, S.L., & Ranganathan, R. Reorganizing muscle coordination using mental imagery and augmented visual feedback. Poster at the annual meeting of the Society for the Neural Control of Movement; 2018 May 1-4; Santa Fe, NM.

Liyanagamage (Jayasinghe) S.A., Bertucco M., Ragusa G., & Sanger T.D. Task-congruent visualizations increase muscle awareness in subjects with dystonia during a one-dimensional myocontrol task. Poster at the annual meeting of the Society for the Neural Control of Movement; 2016 Apr 24-29; Montego Bay, Jamaica.

Liyanagamage (Jayasinghe) S.A., Bertucco M., & Sanger T.D. Vibratory feedback and visualizations increase muscle awareness and task performance in subjects with dystonia during a redundant, one-dimensional myocontrol task. Poster at the annual meeting of the Society for Neuroscience; 2015 Oct 17-21; Chicago, IL.

Liyanagamage (Jayasinghe) S.A., Bertucco M., Bhanpuri N.H., & Sanger T.D. Effects of different modes of vibratory feedback on muscle use during a redundant, one-dimensional myocontrol task. Talk given at the annual meeting of the Biomedical Engineering Society; 2015 Oct 7-10; Tampa Bay, FL.

Liyanagamage (Jayasinghe) S.A., Bertucco M., Bhanpuri N.H., & Sanger T.D. Effects of vibratory feedback on efficient muscle use during a redundant, one-dimensional myocontrol task. Poster at the annual meeting of the Society for Neuroscience; 2014 Nov 15-19; Washington, D.C.

Liyanagamage (Jayasinghe) S.A., Bertucco M., Bhanpuri N.H., & Sanger T.D. Preferential use of muscle after vibratory feedback during a two- muscle myocontrol task. Poster at the annual meeting of the Society for the Neural Control of Movement; 2014 Apr 21-25; Amsterdam, Netherlands.

Community Engagement

Invited talks:

  1. University of Minnesota – Twin Cities - April 2022 Design of Medical Devices conference, “Neurorehabilitation Robotics” session “Examining hemisphere-specific movement deficits to develop personalized neurorehabilitation strategies”
  2.  Marquette University & Medical College of Wisconsin - February 2021 Department of Biomedical Engineering “Motor lateralization and its role in stroke rehabilitation”
  3. Marquette University - April 2021 Neuromotor control laboratory “NeuroGroup” series “Pursuing an academic career in motor control and motor rehabilitation”
  4. Michigan State University - October 2017 Department of Kinesiology “Non-invasive sensory techniques for solving motor learning problems in rehabilitation”

Awards and honors:

  1. Postdoctoral Association Spring Travel Award, Michigan State University: 2018
  2. Jenny Wang Excellence in Teaching Award, University of Southern California: 2017
  3. Provost Fellowship, University of Southern California: 2011-2017
  4. Fred Grodins Best Poster award - Neuroengineering, USC: 2015
  5. Alpha Eta Mu Beta Biomedical Engineering Honor Society, Georgia Tech: 2009-2010
  6. Tau Beta Pi Engineering Honor Society, Georgia Institute of Technology: 2009
  7. Society of Women Engineers Annual Scholarship, Georgia Institute of Technology: 2008-2010
  8. Dean’s List, Georgia Institute of Technology: 2007-2010

Google Scholar profile