Leslie Morse, DO

Department Head, Department of Rehabilitation Medicine

Leslie Morse

Contact Info


Office Phone 612-625-2661

Office Address:
500 Boynton Health Service Bridge
410 Church St. SE
Minneapolis, MN 55455

Mailing Address:
Dept. of Rehabilitation Medicine
MMC 297
420 Delaware St. SE
Minneapolis, MN 55455

Administrative Assistant Name
Dan Kelly

Administrative Phone

Administrative Email

Administrative Fax Number

MD, DO, University of New England College of Osteopathic Medicine, 2001

Residency in Physical Medicine and Rehabilitation, Boston Medical Center

Internship, NH-Dartmouth Family Practice Residency, Concord, NH


Dr. Leslie Morse obtained her Doctor of Osteopathic Medicine degree from the University of New England College of Osteopathic Medicine followed by her residency in Physical Medicine and Rehabilitation at Boston Medical Center. She is board certified by the American Board of Physical Medicine and Rehabilitation. Dr. Morse continues to work on local and national level to promote the field of rehabilitation medicine. 

Professional Associations

  • Member, Research Committee Member, Association of Academic Physiatrists
  • International Society for Clinical Densitometry


Research Summary/Interests

Dr. Morse's research interests include the impact of mechanical unloading on bone metabolism and the development of novel stem cell therapies for motor recovery after SCI. 

Research Funding Grants

  • Department of Defense
    SCI170159 ($638,000)

    Role: Co-investigator
    2018 - 2021
    Assistive Technology and Functional Outcomes following Spinal Cord Injury (Monden PI) 
    The aims of this study are to: (1) examine perceived barriers to or facilitators of assistive technology (AT) access and utilization and the impact on functional and psychosocial outcomes after tetraplegia, (2) assess for variations in use of AT across insurance providers and socioeconomic status in Veterans and civilians with tetraplegia, (3) assess the relationship between AT use and productivity (employment/school), and (4) assess the relationship between AT and psychosocial outcomes.
  • NIDILRR, Department of Health and Human Services ($2,415,292)
    Role: Co-Project Director
    2016 - 2021

    Rocky Mountain Regional Spinal Injury System 
    The goals of this project are to (1) harness our existing multidisciplinary system of rehabilitation care designed specifically to meet the needs of individuals with SCI to extend the Model Systems knowledge base, (2) contribute to improving long term SCI outcomes through participation in site-specific and collaborative clinical trials and research projects, (3) contribute to the SCI model systems national database through longitudinal assessment of long term SCI outcomes, (4) Contribute to improved long term SCI outcomes by conducting a research project designed to reduce sublesional neuropathic pain following SCI.
  • NIDILRR, Department of Health and Human Services
    H133A150065 (Nash PI)
    Role: Co-investigator
    2016 - 2021

    Lifestyle intervention targeting enhanced health and function for persons with chronic SCI in caregiver/care-receiver relationships: effects of caregiver co-treatment
    The goals of this project are to: 1) determine the efficacy of a lifestyle intervention to improve health and function of individuals with SCI.
  • Department of Defense
    W81XWH-14-SCIRP-CTA ($2,478,827)
    Role: PI
    2015 - 2020

    Effects of Ekso-assisted gait training on Bone Health and Quality of Life: A Randomized Clinical Trial
    The goals of this project are to 1) determine whether exoskeleton-assisted gait training increases bone strength in the paralyzed lower extremity and 2) determine whether exoskeleton-assisted gait training improves quality of life after SCI. Secondarily, to determine whether gait training improves the following related outcomes and mediators of quality of life: mood, pain, and cortical activity of related emotional networks in the brain.
    R01 AR064793-01A1 (Battaglino PI)
    Role: Co-investigator
    2015 - 2020

    Regulation of gastric and osteoclast acidification by Snx10
    The specific aims to be addressed in this project are: 1) Determine the cellular mechanisms by which Snx10 regulates osteoclast function. 2) Determine the role of osteoclastic expression of Snx10 on bone homeostasis in vivo. 3) Determine the whole of gastric expression of Snx10 on bone homeostasis in vivo.


Board Certifications

Physical Medicine and Rehabilitation (ABPMR)