S.Hossein Fatemi

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Credentials

MD, PhD

Bio

I received my BS in Biology from Baylor University, Texas. I completed my masters and PhD in Human Anatomy from the University of Nebraska Medical Center. I obtained my MD from Case Western Reserve University, and further completed three postdoctoral fellowships in Pharmacology, Biochemistry (University of Texas Health Sciences Center), and Anatomy (McGill University, Canada).I am a Professor of Psychiatry and Neuroscience and Emeritus for the Bernstein Professorship in Adult Psychiatry at the University of Minnesota Medical School and my research has focused on the biological basis of neurodevelopmental disorders, primarily autism and schizophrenia. I have over 140 publications, nearly 9000 citations and an h-index of 49.My clinical interests have focused on the treatment of schizophrenia, bipolar disorder, and major depression. I have over 20 years of experience in research and treatment of major psychiatric disorders. I am an Elected Fellow of the American College of Psychiatrists, an Elected Fellow of the American College of Neuropsychopharmacology, and a Fellow of the Collegium Internationale Neuropsychopharmacologicum.Within the medical school and university, I am the Academic Advisor for 3rd and 4th year medical students, and the medical student admissions interviewer. I am also the High School Summer Research Apprenticeship Program Supervisor. Within the department, I am a member of the Psychiatry Residency Committee , Residency Training Committee , and on the Medical Student Clerkship Education Sub-Committee .

Research Summary

Dr. Fatemi's research focuses on the neurodevelopmental mechanisms that contribute to normal structure and function of the brain and which, under certain circumstances, cause neuropsychiatric disorders. His research has been conducted on two levels: one at the level of human brain dysfunction (postmortem studies involving schizophrenic, depressed, bipolar, and autistic patients) and secondly on development of an animal model to mimic schizophrenia and autism (prenatal viral infection in mice). Dr. Fatemi has also investigated the effects of various psychotropic agents, e.g., olanzapine, clozapine, fluoxetine, valproic acid, haloperidol, and lithium, on expression of genes of interest in rats following chronic administration of each drug. The ultimate goals of Dr. Fatemi's research are to better understand the genesis of these disabling disorders and to treat patients afflicted by them. Dr. Fatemi's research has been funded by multiple grants from the National Institutes of Health, the Stanley Medical Research Institute, the National Alliance for Research in Schizophrenia and Depression, and the Minnesota Medical Foundation. His research has been published in top journals including Molecular Psychiatry, Synapse, Molecular Autism, and Translational Psychiatry. Dr. Fatemi has published 121 articles, 33 book chapters, and edited five books. Dr. Fatemi is an Associate Editor of Cerebellum and Ataxias, a Regional Editor (USA) for Central Nervous System Agents in Medicinal Chemistry, and on the editorial boards of multiple journals including Molecular Psychiatry, PLoS One and Pharmacopsychiatry.