Stephen Huddleston, MD, PhD

Associate Professor, Division of Cardiothoracic Surgery, Department of Surgery

Stephen Huddleston

Contact Info

Office Phone 612-625-3902

Fax 612-625-1683

Mailing Address:
Cardiothoracic Surgery
420 Delaware Street SE
MMC 207
Minneapolis, MN 55455

Administrative Assistant Name
Rick Castillo

Administrative Phone

Administrative Email

Associate Professor, Division of Cardiothoracic Surgery, Department of Surgery

Director, Lung Transplantation Program

Chief, Cardiothoracic Surgery, St. John’s Hospital, Maplewood, MN

Cardiothoracic Surgeon

MD, Columbia University College of Medicine

Residency in General Surgery, University of Minnesota

Fellowship, Cardiovascular and Thoracic Surgery, Johns Hopkins Hospital

PhD, Surgery, University of Minnesota

BA, Biochemistry with Highest Distinction, University of Kansas



  • Cardiothoracic Surgery
  • Lung Transplantation
  • Circulatory Support

Awards & Recognition

  • Cassius Ellis Award, 2009
  • The Doctor David Gaviser Mount Sinai Surgical Research Award, 2008
  • Richard C. Lillehei, MD/Earl Bakken Prize, 2004

Professional Associations

  • International Society for Heart and Lung Transplantation
  • Society of Thoracic Surgeons
  • American College of Surgeons


Research Summary/Interests

  • Surgical outcomes in lung transplantation
  • Use of ex vivo lung perfusion in standard of care as well as expanded criteria lung donors
  • The tracking and characterization of graft antigen-specific CD4+ T cells responses with respect to antibody mediated rejection and chronic lung allograft disease in the lung transplant recipients


Board Certifications

  • American Board of Surgery
  • American Board of Thoracic Surgery

Clinical Interests

Lung transplantation for end-stage lung disease, valve repair and replacement, complex and redo cardiac surgery, aortic dissection repair, coronary artery bypass grafting, and surgical treatment of atrial fibrillation.