Department of Medicine Faculty

Bio

Administrator Info
Name: Bill Clark
Email: wclark10@umphysicians.umn.edu
Mail: 420 Delaware Street SE
MMC 508 Mayo
8508A (Campus Delivery Code)
Minneapolis, MN 55455

Summary
Dr Nijjar received his early education in India, and after completing his Internal Medicine residency and Cardiac Prevention training in Philadelphia, he moved to Minneapolis for fellowship training in Cardiology and Advanced Cardiac Imaging at the University of Minnesota. He has a general cardiology practice, with a focus on cardiac prevention. He is involved in the conduct of clinical trials in behavioral cardiology, including studying the benefits of meditation in treatment of heart disease. He is the medical director of cardiac CT, and is passionate about the optimal use of CT in diagnosis of various heart conditions.

Research Summary

Dr Nijjar's research interests include optimal use of cardiac CT and MRI, behavioral cardiology, and benefits of meditation in treatment of heart disease.

Clinical Summary

Cardiac Imaging; Coronary artery disease; Lipid/Cholesterol disorders; Cardiac Prevention; Cardiac CT; Cardiac MRI; Wellness/Integrative Medicine; South Asian Health

Bio

Administrator Info
Name: Kelly Denno
Phone: 612-301-3285
Mail: 420 Delaware Street SE
MMC 284
Minneapolis, MN 55455

Summary
Dr. Nixon is a Professor of Internal Medicine and Pediatrics. He serves as the director of the Essentials of Clinical Medicine as well as the Vice Chair for Education in the Department of Medicine. He is board certified in both Internal Medicine and Pediatrics. He is a graduate of the University of Oklahoma College of Medicine and completed his residency training at the University of Minnesota, where he was also Chief Resident. His interests include medical education, physical diagnosis and evidence based medicine.

Clinical Summary

Evidence-based medicine; Internal medicine; Medical Education; Pediatrics; Physical diagnosis

Bio

Ana Núñez, MD, FACP is a Professor of General Internal Medicine and Vice Dean for Diversity, Equity and Inclusion at the University of Minnesota. She received her Doctorate in Medicine from Hahnemann University and Bachelor of Science in Chemistry from Wilkes University. She has fellowships in medical education from Michigan State University and health services research from the Association of American Medical Colleges (AAMC). She is nationally recognized as a medical education and health services researcher, having developed novel curricula in the areas of sex and gender medicine, primary care, trauma/violence prevention and cultural competence.

Administrator Information

Amber Prahl 
aprahl@umn.edu 
Office: 612-626-5424 
 

Expertise

• Primary Care
• Internal Medicine
• Women’s Health
• Community Health

Professional Associations

• Chair, Northeast Consortium on Cross-Cultural Care and Medical Practice 
• National Consortium for Multicultural Education and Health Professionals
• Society for General Internal Medicine
• American Medical Women's Association
• National Academy on Women's Health Education 
• Board, Women Against Abuse

Research Summary

Sex and gender health disparities
Health services
Health literacy
Women’s heart health

Teaching Summary

Diversity, equity & inclusion; Health disparities

Clinical Summary

Primary Care; Internal Medicine; Women’s health; Community health

Bio

Dr. O’Leary is an Assistant Professor of Medicine in the Division of Hematology, Oncology and Transplantation where he serves as an oncologist with a focus on the treatment of blood cancers such as multiple myeloma, lymphoma and leukemia utilizing chemotherapy, immunotherapy, cellular therapy, and bone marrow transplant.

Creative Activity Summary

• Clinical Trials
• Bone Marrow Transplant and Cellular Therapies

Teaching Summary

Hematology

Clinical Summary

"Multiple Myeloma, T-cell lymphoma, Cellular therapies, Bone Marrow Transplant"

Bio

Administrator Info
Name: Esther Almeida
Email: ealmeida@umn.edu
Mail: 2231 6th Street SE
4-132
Minneapolis, MN 55455

Summary
Jin O-Uchi MD, PhD is Assistant Professor of Medicine at the Lillehei Heart Institute, Department of Medicine, Cardiology Division at the University of Minnesota. Dr. O-Uchi received the MD and PhD degree from Jikei University School of Medicine in Japan. He did a postdoctoral fellowship at University of Rochester and worked as an Instructor and a Research Assistant Professor at Thomas Jefferson University. Prior to his position with the U of MN, , he was at Cardiovascular Research Center at Brown University and Rhode island Hospital as an Assistant Professor of Medicine. His research potential has been recognized at a national level by grant awards from NIH/NHLBI, NIH/NIGMS, American Heart Association (AHA) and American Physiological Society (APS). He serves on several editorial boards for publications including Frontiers in Physiology; Frontiers in Cardiovascular Medicine; Frontiers in Genetics; Frontiers in Cell and Developmental Biology; World Journal of Cardiology; Journal of Biochemistry and Molecular Biology Research; and JSM Biochemistry and Molecular Biology. Dr. O-Uchi is a Fellow of Cardiovascular Section of American Physiological Society (FCVS), and a Trustee (elected) of Japanese Physiological Society (JPS). He is a member of the and the American Heart Association (AHA), International Society for Heart Research (ISHR), American Physiological Society (APS), Biophysical Society (BPS), and Cardiac Muscle Society, among others. His research interests include cardiac excitation-contarction/metabolism coupling, heart failure, sudden cardiac death, cardiac channelopathies, and cardiac mitochondrial biology. Come work with us! Visit https://med.umn.edu/lhi/about/jobs to see open positions in the O-Uchi lab.

Research Summary

Arrhythmia Heart Failure Adrenergic Signaling Ion Channels Mitochondria

Clinical Summary

Arrhythmia; Heart Failure

Bio

Administrator Info
Name: Admin
Phone: 612-624-9996
Fax: 612-625-4410
Email: idimdivision@umn.edu
Mail: Mayo Memorial Building, MMC 250, 420 Delaware Street S.E., Minneapolis, MN 55455

Summary
After graduating from Damascus University, Faculty of Medicine in 1998, Dr. Obeid completed his Internal Medicine training in 2003 and Infectious Diseases training in 2007 at Henry Ford Hospital, Detroit, Michigan. Dr. Obeid practiced Internal Medicine at William Beaumont Hospital and Infectious Diseases at St. John Hospital and Medical Center where he attended on inpatient consultation rounds and supervised Infectious Diseases fellows, Internal Medicine residents, and medical students. He also was an Assistant Professor at Wayne State University in Detroit, Michigan. Dr. Obeid served as the consultant of latent and active TB cases for the Macomb County Health Department in Michigan. His research activities focused on infections in immunocompromised patients, which lead Dr. Obeid to pursue a one year special Fellowship training in the field of Transplant Infectious Diseases at the Cleveland Clinic Foundation. After his graduation from this special training in 2014 he joined the Infectious Diseases Division at the University of Minnesota as an Assistant Professor. Dr. Obeid's research interests are focused on therapies and outcomes in immunocompromised patients especially solid organ and bone marrow transplant recipients.

Research Summary

Clinical research and research related to outcomes in immuno-compromised patients

Clinical Summary

Solid Organ Transplant; Infectious Disease; Nosocomial Infections; Infections in Immunocompromised patients; Bone Marrow Transplant Infectious Diseases; Fever of Unknown Origin

Bio

Administrator Info
Name: Courtney Bridell
Email: bride030@umn.edu
Mail: 420 Delaware Street SE
MMC 741
Minneapolis, MN 55455

Summary

Dr. Andrew Olson is an Associate Professor of Medicine and Pediatrics at the University of Minnesota Medical School, where he practices hospital medicine and pediatrics. He serves as the founding Director of the Division of Hospital Medicine within the Department of Medicine. His clinical interests focus on innovation in hospital medicine, care of complex inpatients, bedside procedures, and multispecialty collaboration.

Dr. Olson's academic work focuses on two major areas: the nature and development of clinical reasoning as well as methods to measure and decrease diagnostic error and has been a leader of multiple national and international projects to improve clinical reasoning education. Dr. Olson presently serves as the Director of Medical Education Research and Innovation in the Medical Education Outcomes Center, focusing on linking education with clinical and workforce outcomes as well using EHR metadata to characterize clinical care, teamwork, and the clinical learning environment.

Bio

Administrator Info
Lab Phone: 612-624-8201
Phone: 612-626-5475
Email: mccadmin@umn.edu
Mail: Cancer and Cardiovascular Research Building
1st Floor Mailroom CCRB
2812A (Campus Delivery Code)
2231 6th St SE
Minneapolis, MN 55455

Summary
Julie Ostrander, Ph.D. is an Assistant Professor in the Department of Medicine at the University of Minnesota and a member of the Cellular Mechanisms of Cancer Program at the University of Minnesota Masonic Cancer Center. Dr. Ostrander received her Ph.D. from the University of North Carolina at Chapel Hill. She holds memberships in the American Association for Cancer Research and the Endocrine Society.

Research Summary

Dr. Ostrander's research focuses on studying the scaffolding protein PELP1 in the context of breast cancer progression. Our recent studies have found that PELP1 signaling 1) promotes cell survival in the presence of tamoxifen, 2) enhances breast epithelial cell migration through upregulation inflammatory cytokines and chemokines, and most recently 3) promotes CSC phenotypes in models of ER-positive breast cancer. We have identified a novel cytoplasmic interaction between PELP1 and SRC-3. The objective of our current research is to identify the molecular mechanisms associated with PELP1-induced BCSC phenotypes and therapy resistance.

Research Interest: Solid Tumors

Bio

Administrator Info
Name: DHM Admin Team
Email: dhmadmin@umn.edu
Phone Number: 612-624-0579
Fax Number: 612-624-3189

Summary
Born and raised in Minnesota and studied at the University of Minnesota Medical School and completed residency in Internal Medicine/Pediatrics at the University of Minnesota. Managed outpatient care in an underserved area of Northern California for two years and now returning to Minnesota to work as a MedPeds Hospitalist and focus on undergraduate/graduate medical education and mentorship. Board certified in Internal Medicine (2018) and Pediatrics (2018)

Clinical Summary

• Education
• Inpatient/Outpatient Transitions
• Communication

Bio

Dr. Suman Pal completed his medical school at Maulana Azad Medical College, New Delhi, India and earned his MBBS degree with Distinction in Anatomy from the University of Delhi (2015). Following this, he completed an Internal Medicine residency program from Westchester Medical Center, New York, and Medical Education Scholars program from University of New Mexico. Dr. Pal is passionate about health equity, promoting inclusivity, equity, and diversity in academic medicine. He is interested in academic medicine and medical education research.

Research Summary

Medical Education, Health Equity, DEI in medicine, LGBTQ+ health, COVID-19 vaccine acceptance

Teaching Summary

DEI, Health equity, Anti-racism in medicine

Service Summary

Awards and Recognition Received:
University of New Mexico Hospital Medicine Rush Pierce Outstanding Professionalism Award (2022)

Professional Memberships and Affiliations:
American College of Physicians; Society of Hospital Medicine

Clinical Summary

LGBTQ health, Hospital Medicine, Healthcare disparities

Bio

Administrator Info
Name: Colleen Doyle
Email: doyl0050@umn.edu

Summary
Brooke Palmer is a licensed clinical health psychologist. She earned her PhD in Health Psychology at the University of North Carolina-Charlotte. She engages in clinical work in outpatient and inpatient settings often focusing on supporting patients' emotional wellbeing who are living with acute or chronic health conditions. She has targeted training in working with patients living with disorders of gut-brain interaction and chronic digestive issues. Her research interests include women’s health, binge eating, integrated psychological consultation models in healthcare settings, interprofessional health education and practice, and psychogastroenterology. She has engaged in undergraduate education in general and health psychology as well as supporting graduate psychology learners and interprofessional learners.

Research Summary

• Psychological treatment for patients with chronic digestive disorders
• Inpatient psychology consultation-liaison models and effectiveness
• Interprofessional health education and practice
• Treatment of binge eating
• Women's health

Teaching Summary

Integration of behavioral health into medical settings; interprofessional collaboration

Clinical Summary

Psychogastroenterology; inpatient consultation; binge eating, cardiovascular health; diabetes management; oncology

Bio

Angela Panoskaltsis-Mortari, PhD is a Professor of Pediatrics in the Division of Blood and Marrow Transplant & Cellular Therapy. She is also a Professor of Medicine in the Division of Pulmonary, Allergy, Critical Care and Sleep. Dr. Panoskaltsis-Mortari is the Director of the Cytokine Reference Laboratory, the Director of the 3D Bioprinting Facility at the University of Minnesota and Vice Chair for Research for the Department of Pediatrics.
Dr. Panoskaltsis-Mortari received her PhD from the University of Western Ontario. She was a post-doctoral fellow in the Department of Pathology at the University of Alabama and a post-doctoral research associate in the Department of Pediatrics at the University of Minnesota. She joined the University of Minnesota faculty in 1995.
Dr. Panoskaltsis-Mortari has board certification from the American Board of Medical Laboratory Immunology. She is a member of numerous immunology, pulmonary, and hematology professional societies, and the author of over 275 articles which have appeared in such publications as Advanced Materials, Journal of Clinical Investigation, Blood, Biology of Blood and Marrow Transplantation, and American Journal of Physiology (Lung, Cell. & Mol. Physiol.).

Research Summary

With 25 years of experience in animal models of stem cell transplant, lung injury, mesenchymal stem/stromal cell therapy and the biology of graft-vs-host disease (GVHD) after bone marrow transplant, Dr. Angela Panoskaltsis-Mortari's work has evolved into the bioengineering field, and she is recognized as one of the thought leaders in lung bioengineering. Dr. Panoskaltsis-Mortari's laboratory research currently focuses upon 2 major themes: 1) bioengineering autologous tissues such as trachea and esophagus using 3D bioprinting and customized hydrogels including decellularized extracellular matrix; and 2) 3D bioprinting of cancer models.
Dr. Panoskaltsis-Mortari established and directs the 3D Bioprinting Facility at the University of Minnesota. She also directs the UMN Cytokine Reference Laboratory (a CLIA-licensed facility). She is a member of the Stem Cell Institute, the Institute for Engineering in Medicine, the Lillehei Heart Institute, the Masonic Cancer Center, the Center for Immunology, and the Robotics Institute. She is funded by the NIH, has mentored many post-docs, MD trainees, graduate students and undergrads in various training programs. Her goal is to realize the potential of regenerative medicine by converging the fields of stem cell biology, mechanical & biomedical engineering, biomaterials, physiology, robotics, and surgery to bioengineer autologous tissues/organs for transplant using a patient's own cells that would not be rejected by their immune system.

Bio

Dr. Paranjpe graduated medical school in 2017 from Wayne State University School of Medicine. He went on to complete his residency in pediatrics at Western Michigan University in 2021.

Bio

Administrator Info
Name: Ms. J. Knapp
Phone: 612-626-1422
Fax: 612-625-6919
Email: jknapp@umn.edu
Mail: 420 Delaware Street SE, MMC 480, Minneapolis, MN 55455

Summary
Dr. Patel received a BS in Molecular Biology from Vanderbilt University in 1996. He then attended Kirksville College of Osteopathic Medicine, receiving a Doctor of Osteopathy degree in 2001. Dr. Patel then pursued residency in Internal Medicine at McGaw Medical Center of Northwestern University. He followed this with a clinical research fellowship at Winthrop University Hospital (Mineola, NY) from 2004-2006. In 2006 he joined the Hematology, Oncology and Transplantation fellowship at the University of Minnesota and in July 2010 became a faculty member of the Division. Dr. Patel is a physician-scientist researching oncolytic virus for lung cancer. In 2019, Dr. Patel became the associate program director for the hematology, oncology, and transplantation fellowship program. He also leads the experimental therapeutics phase I clinical program at the University of Minnesota.

Clinical Summary

Thoracic oncology; Experimental therapies; Head and neck cancer; Mesothelioma

Bio

Administrator Info
Name: Emily Olmsted-Morales
Phone: 612-624-0999
Email: olmst111@umn.edu
Fax: 612-625-2174

Clinical Summary

General pulmonary medicine; Transplant and critical care medicine

Bio

Administrator Info
Name: Emily Olmsted-Morales
Phone: 612-624-0999
Email: olmst111@umn.edu
Fax: 612-625-2174

Summary
Dr. Katie Pendleton is a Minnesota native who joined the faculty at the University of Minnesota in 2017. She is trained in both pulmonary and critical care medicine and practices in both arenas by seeing patients in the ICU as well as general pulmonary clinic. Dr. Pendleton's research interests include quality improvement, implementation science, and outcomes research in ICU medicine. She is specifically interested in improving practices surrounding management of acute respiratory distress syndrome (ARDS) and hospital-acquired delirium in ICU patients. Dr. Pendleton also plays an active role in medical education and serves as a Core Faculty Member for the Internal Medicine Residency Program, with a specific focus on curriculum development and design.

Research Summary

• Sepsis
• ARDS
• ICU Sedation and Delirium

Clinical Summary

Critical Care Medicine; ARDS; ICU Delirium; Sepsis; General Pulmonary Medicine

Bio

Our laboratory has a long-term interest in understanding the molecular mechanisms controlling lineage-specific differentiation of pluripotent stem cells (PSC), which has led to the efficient generation of  PSC-derived myogenic progenitor cells endowed with in vivo regenerative potential. Current research projects focus on the effect of the environment on the engraftment and maturation of PSC-derived myogenic progenitors, the development of allogeneic and autologous cell therapy for muscular dystrophies (MD), and application of MD patient-specific iPSC-derived muscle derivatives for disease modeling and drug discovery.

Creative Activity Summary

Full list of publications at Experts@Minnesota or PubMed.

1. Baik J, Ortiz-Cordero C, Magli A, Azzag K, Crist SB, Yamashita A, Kiley J, Selvaraj S, Mondragon-Gonzalez R. Perrin E, Maufort JP, Janecek JL, Lee RM, Stone LH, Rangarajan P, Ramachandran S, Graham ML, & Perlingeiro RCR. (2023). Establishment of skeletal myogenic progenitors from non-human primate induced pluripotent stem cells. Cells, 12(8), 1147; https://doi.org/10.3390/cells12081147.
2. Singh BN, Yucel D, Garay BI, Tolkacheva EG, Kyba M, Perlingeiro RCR, van Berlo J, & Ogle BM, (2023) Proliferation and Maturation: Janus and the art of engineered cardiac tissue. Circulation Research, 132(4):519-540.  PMCID: PMC9943541.
3. McKenna DH & Perlingeiro RCR, (2023) Development of allogeneic iPS cell-based therapy: from bench to bedside. EMBO Molecular Medicine, 15(2):e15315. PMCID: PMC9906386.
4. Azzag K, Bosnakovski D, Tungtur S, Salama P, Kyba M, & Perlingeiro RCR, (2022) Transplantation of pluripotent stem cell-derived myogenic progenitors counteracts disease phenotypes in a mouse model of FSHD. NPG Regenerative Medicine,  7(1):43. PMCID: PMC9440030.
5. Garay BI, Givens S, Stanis N, Magli A, Yücel D, Abrahante JE, Goloviznina NA, Soliman HAN, Dhoke NR, Baik J, Kyba M, van Berlo JH, Ogle B, & Perlingeiro RCR, (2022) Inhibition of mitogen-activated protein kinase pathway enhances maturation of human iPSC-derived cardiomyocytes. Stem Cell Reports. 17(9):2005-2022. PMCID: PMC9481895.
6. Kim H, & Perlingeiro RCR, (2022) Generation of human myogenic progenitors from pluripotent stem cells for in vivo regeneration. Cellular and Molecular Life Sciences. 8;79(8):406. doi: 10.1007/s00018-022-04434-8. PMCID: PMC9270264.
7. Ortiz-Cordero C, Bincoletto, C, Dhoke N, Selvaraj S, Magli A, Zhou H, Kim D-H, Bang AG, & Perlingeiro RCR, (2021), Defective autophagy and increased apoptosis contribute toward the pathogenesis of FKRP-associated muscular dystrophies. Stem Cell Reports. 16(11):2752-2767. PMCID: PMC8581053.
8. Dhoke N, Kim H, Selvaraj S, Oliveira NAJ, Azzag K, Tungtur S, Ortiz-Cordero C, Kiley J, Lu QL, Bang A, & Perlingeiro RCR, (2021), A universal gene correction approach for FKRP-associated dystroglycanopathies to enable autologous cell therapy. Cell Reports. 36(2):109360. PMCID: PMC8327854.
9. Ortiz-Cordero C, Magli A, Dhoke N, Kuebler T, Selvaraj S, Oliveira NA, Zhou H, Sham YY, Bang AG, & Perlingeiro RCR, (2021), “NAD+ enhances ribitol and ribose rescue of α-dystroglycan functional glycosylation in human FKRP-mutant myotubes”. Elife, 2021 10:e65443. PMCID: PMC7924940
10. Ortiz-Cordero C, Azzag K, & Perlingeiro RCR, (2021), “Fukutin-Related Protein: from Pathology to Treatments”. Trends in Cell Biology, 31:197-210. PMID: 33272829 (cover article).
11. Kim H, Selvaraj S, Kiley J, Azzag K, Garay BI, & Perlingeiro RCR, (2021), “Genomic safe harbor expression of PAX7 for the generation of engraftable myogenic progenitors”. Stem Cell Reports, 16:10-19.PMCID: PMC7815936
12. Baik J, Felices M, Yingst A, Theuer, CP, Verneris MR, Miller JS, & Perlingeiro RCR,(2020), “Therapeutic effect of TRC105 and decitabine combination in AML xenografts”. Heliyon, 6(10):e05242. PMCID: PMC7566100.
13. Incitti T, Magli A, Jenkins J, Lin K, Yamamoto A and Perlingeiro RCR, (2020), “Pluripotent stem cell-derived skeletal muscle fibers preferentially express oxidative myosin heavy-chain isoforms: new implications for Duchenne Muscular Dystrophy”. Skeletal Muscle, 10(1):17. PMCID: PMC7268645
14. Azzag K, Ortiz-Cordero C, Oliveira NAJ, Magli A, Selvaraj S, Tungtur S, Upchurch W, Iaizzo PA, Lu QL and Perlingeiro RCR, (2020) “Efficient Engraftment of Pluripotent Stem Cell-Derived Myogenic Progenitors in a Novel Immunodeficient Mouse Model of Limb Girdle Muscular Dystrophy 2I”. Skeletal Muscle, 10(1):10. PMCID: PMC7175515.
15. Selvaraj S, Mondragon-Gonzalez R, Xu B, Magli A, Kim H, Lainé J, Kiley J, McKee H, Rinaldi F, Aho J, Tabti N, Shen W, & Perlingeiro RCR, (2019) “Screening identifies small molecules that enhance the maturation of human pluripotent stem cell-derived myotubes”. eLIFE, 8. pii: e47970. PMCID: PMC6845233.
16. Selvaraj S, Dhoke N, Kiley J, Aierdi AJM, Mondragon-Gonzalez R, Killeen G, Oliveira VKP, Tungtur S, Munain AL & Perlingeiro RCR, (2019) “Gene Correction of Limb Girdle Muscular Dystrophy Type 2A Patient-Specific iPS Cells for the Development of Targeted Autologous Cell Therapy”. Molecular Therapy,27:2147-2157. PMCID: PMC6904833.
17. Selvaraj S, Kyba M & Perlingeiro RCR, (2019) “Pluripotent Stem Cell-Based Therapeutics for Muscular Dystrophies” Trends in Molecular Medicine. 25:803-816. PMCID: PMC6721995. (cover article)
18. Mondragon-Gonzalez R, Azzag K, Selvaraj S, Yamamoto A & Perlingeiro RCR, (2019) “Transplantation studies reveal internuclear transfer of toxic RNA in engrafted muscles of myotonic dystrophy 1 mice”. eBioMedicine. 47:553-562. PMCID: PMC6796515.
19. Magli A, Baik J, Pota P, Ortiz Cordero C, Kwak IY, Garry DJ, Love PE, Dynlacht BD and Perlingeiro RCR, (2019) “Pax3 cooperates with Ldb1 to direct local chromosome architecture during myogenic lineage specification”. Nature Communications, 10:2316. PMCID: PMC6534668.

Full list of publications at Experts@Minnesota or PubMed.

Bio

Administrator Info
Name: Ashley Fuchs
Phone: 612-624-0999
Email: fuchs@umn.edu
Fax: 612-625-2174

Summary
Dr. Perlman received his B.A. in biology from Carleton College in Northfield, Minnesota in 1989. After college he worked as a research assistant in the lab of Dr. Radovan Zak at the University of Chicago, working mainly on projects relating to the recovery from injury of skeletal and cardiac muscle. He subsequently returned to Minnesota to attend medical school and received his M.D. from the University of Minnesota in 1996. After completing his residency in Internal Medicine at Hennepin County Medical Center, he entered the Pulmonary and Critical Care Medicine Fellowship program at the U of MN.

Clinical Summary

General pulmonary medicine; Critical care medicine; Pulmonary fibrosis; Environmentally-associated lung disease

Bio

Administrator Info
Name: Drew Keup
Email: keupx013@umn.edu
Lab Phone: 612-626-6100
Mail: 420 Delaware ST SE
MMC 108
Minneapolis, MN 55455

Summary
Dr. Erik Peterson joined the division of Rheumatic and Autoimmune Diseases in July, 2002. He is a member of the interdisciplinary Center for Immunology and its Autoimmunity Program, as well as a member of the Cancer Center. He is an immunologist with a scientific interest in those molecules that regulate the development and function of the immune system and prevent or promote the development of autoimmunity. He is also practices general rheumatology and participates in Resident and Fellow teaching.

Research Summary

Research in the Peterson laboratory

Dr. Erik Peterson has strong interests in the molecular underpinnings of autoimmune diseases, including rheumatoid arthritis, lupus, and myositis. His laboratory utilizes genetic, biochemical, and primary human sample-based approaches to investigating the mechanisms whereby recently identified “risk” genes predispose to development of autoimmune disease. Dr. Peterson's group recently identified a role for Ptpn22, a potent “risk” gene for many autoimmune diseases, in the promotion of toll-like receptor signaling and type 1 interferon production. He is currently investigating the role of Ptpn22 in myeloid cell functions in systemic lupus and in responses to immunization, and is characterizing the molecular mechanism of Ptpn22 promotion of type 1 interferon signals.

Leukocyte activation and development

Investigations carried out in Dr. Erik Peterson’s laboratory aim to increase understanding of the molecular mechanisms behind newly identified risk genes associated with autoimmune diseases. The laboratory uses human peripheral blood, genetically-altered mice, and transformed cell lines to approach questions concerning the biochemical, cellular, and immune response-modulating functions of susceptibility alleles.

The PTPN22 gene is among the strongest genetic predisposition factors for major human autoimmune diseases, including type 1 diabetes (T1D), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE). PTPN22 encodes lymphoid tyrosine phosphatase (Lyp); a Lyp variant bearing a R620W substitution (“LypW”) is causally associated with disease risk. Lyp is a well-known negative regulator of T cell receptor (TCR) signaling, and most functional genomic work to date has focused on the potential mechanisms of LypW variant action on adaptive immune processes. Despite intensive study, a comprehensive model for LypW mechanism(s) of action in autoimmune disease is lacking.

In collaboration with others at UMN and elsewhere, our group recently demonstrated that PTPN22 plays a critical positive role in regulating pattern recognition receptor (PRR) signaling leading to production of type 1 Interferons (IFN) by myeloid cells. We established that Lyp protein binds and promotes activation of TNF Receptor Associated Factor 3 (TRAF3) during myeloid cell PRR signaling. Lyp also promotes PRR-induced, type 1 IFN-driven anti-viral host defense and suppression of inflammation in the gut and in the joint lining synovium. Importantly, the LypW variant exhibits reduced-function behavior in PRR signaling and in type 1 IFN-governed suppression of inflammation.

Our observations that PTPN22 modulates myeloid cell signaling suggest new potential mechanisms whereby an autoimmunity-associated gene works in concert with suspected environmental stimuli (e.g. viral infections, inflammatory reactions) to result in tissue damage. Our working model holds that PTPN22 potentiates myeloid cell-directed type 1 IFN-dependent anti-microbial host defense andcounter-inflammatory mechanisms. The model also holds that the reduced function LypW variant enhances potential for autoimmunity by increasing host susceptibility to tissue damage by suboptimally-suppressed infections and/or inflammatory reactions. Major questions about the model remain:

1. Is myeloid cell-intrinsic Lyp function sufficient for major host defense and anti-inflammatory PTPN22 actions in vivo?
2. What is the molecular basis for Lyp promotion of TRAF3 signaling?
3. How does LypW function differently in myeloid cell signaling and type 1 IFN-driven processes in vivo?
4. How do Lyp functions in host-defense and inflammation suppression translate into autoimmune disease risk

By experimentally addressing questions such as these, we seek to identify novel therapeutic targets, high-quality biomarkers, and ultimately, the cure for systemic rheumatic diseases.

Clinical Summary

Rheumatoid arthritis; Psoriatic arthritis; Systemic lupus erythematosus

Bio

Administrator Info
Name: DHM Admin Team
Email: dhmadmin@umn.edu
Phone Number: 612-624-0579
Fax Number: 612-624-3189

Summary
Dr. Cuong Pham is an Assistant Professor of Medicine at the University of Minnesota. He completed his residency training at the University of Minnesota in Internal Medicine and Pediatrics. Currently he has a mix of clinic at the Community University Health Care Center (CUHCC), which serves the underserved citizens of Minneapolis, and inpatient wards at the University of Minnesota Medical Center. He has had varying cultural experiences working abroad in Vietnam and South Africa. He also enjoys caring for the growing diverse patient population of the Twin Cities.

Clinical Summary

Immigrant health

Bio

Administrator Info
Name: DHM Admin Team
Email: dhmadmin@umn.edu
Phone Number: 612-624-0579
Fax Number: 612-624-3189

Summary
Dr. Plesac is an Assistant Professor of Medicine at the University of Minnesota. She earned her medical degree from Rush Medical College. She completed her residency in Internal Medicine, followed by a year as a Chief Resident, at the University of Minnesota. She completed an Editorial Fellowship for the Journal of Hospital Medicine in 2018 and has previously held teaching positions and leadership roles in undergraduate medical education. She is currently an Associate Program Director for University of Minnesota Internal Medicine residency program. She is interested in medical education, particularly clinical reasoning curriculum development and implementation. She is board certified in Internal Medicine and practices inpatient medicine at the University of Minnesota Medical Center Fairview.

Research Summary

• Sepsis Education
• Clinical Reasoning

Bio

Administrator Info
Name: DHM Admin Team
Email: dhmadmin@umn.edu
Phone Number: 612-624-0579
Fax Number: 612-624-3189

Summary
Hope Pogemiller, MD, MPH, CTropMed ® is an internal medicine/pediatrics hospitalist, - Assistant Professor, - and Global Health Faculty in the University of Minnesota Department of Medicine. She served as a public health volunteer in Benin (West Africa) and has continued her interest in cross-cultural healthcare in Minneapolis and abroad. She worked with St. Damien's Pediatric Hospital in Port-au-Prince, Haiti, and the International Organization for Migration in Kampala, Uganda. Her work with refugees at the Center for International Health (as a resident) and with the IOM in Uganda led to the creation of an online medical interpreter training module for refugee settings. She worked with the Selian Hospital and Arusha Lutheran Medical Center in Arusha, Tanzania as a Global Health Chief Resident, and she served as an In-Country Clinical Lead for the trial, A Multicenter Randomized Safety and Efficacy Study of Putative Investigational Therapeutics in the Treatment of Patients with Known Ebola Infection, in Sierra Leone. Currently, she leads the inpatient portion of the BRIIDGE program (Bridge to Residency for Immigrant International Doctor Graduates through clinical Experience). With the Center of Excellence in Refugee Health, she is collaborating to update and expand CDC's screening guidelines for newly arrived refugees.

Bio

Administrator Info
Name: Ms. J. Knapp
Phone: 612-626-1422
Fax: 612-625-6919
Email: jknapp@umn.edu
Mail: 420 Delaware Street SE, MMC 480, Minneapolis, MN 55455

Summary
After undergraduate studies in biology at M.I.T., Dr. Potter received M.D. and Ph.D. degrees from Johns Hopkins University. He trained in Internal Medicine at Stanford University Medical Center, and in Hematology and Oncology at Tufts-New England Medical Center. He performed post-doctoral studies at the M.I.T. Center for Cancer Research in the laboratory of Dr. Phillip Sharp. He was on the faculty at Tufts University, the Indiana University Cancer Center and moved to the University of Minnesota in 2006, where he is a member of the Breast Cancer Program at the Masonic Cancer Center.

Research Summary

• Novel therapeutics for breast cancer

Regulation of calpain proteases and their roles in cytoskeletal remodeling; the roles of cytochrome P450 in breast cancer progression
Three enzymatic pathways of arachidonic acid metabolism, involving cyclooxygenases, lipoxygenases and epoxygenases, have been identified in mammalian cells, but only the first two have been mechanistically linked to human cancer. The HIV protease inhibitor ritonavir is a potent inhibitor of epoxygenases that arrests the growth of breast cancer xenografts, but its mechanism of action is unknown. Epoxygenases promote the production of epoxyeicosatrienoic acids (EET’s) that activate Akt kinase. Our studies seek to determine whether epoxygenases are cancer therapeutic targets. The hypothesis to be tested is that epoxygenase activation promotes breast cancer progression by promoting Akt phosphorylation and cancer cell survival. Based on our observations we are asking the following questions: What are the molecular mechanisms by which epoxygenases cause growth dysregulation in breast cancer? Do epoxygenases enhance the transforming activities of oncogenes in mammary carcinoma? Do epoxygenase pathways require Hsp90 activity for cancer cell survival? Targeted lipidomics will be used to assay EET regio- and stereoisomers. These studies will promote further development of epoxygenases as targets for breast cancer therapeutics.

Clinical Summary

Novel therapeutics for breast cancer

Bio

Administrator Info
Name: Karen Fitz
Phone: 612-626-5906
Email: fitz0355@umn.edu

Summary
Dr. Ajay Prakash is a medical oncologist specializing in gastrointestinal malignancies. His research is focused on understanding the relationship between the tumor microenvironment, prognosis, and treatment response, with a specific focus on the role of the microbiome in this process. A better understanding of the microbiome, the community of organisms that reside in most human tissues, may allow us to better tailor treatments and offer patient specific guidance on cancer prevention. Clinically, Dr. Prakash is committed to healthcare equity and the delivery of high-quality, academic medicine to historically underserved communities.

Research Summary

• Gastrointestinal Malignancies
• Microbiome
• Tumor Immunology
• Healthcare Disparities

Teaching Summary

Solid Tumor Oncology

Clinical Summary

Gastrointestinal Malignancies; Healthcare Equity

Bio

Dr. Prekker completed EM/IM combined residency training at HCMC followed by a fellowship in Pulmonary and Critical Care Medicine at the University of Washington-Seattle.  After returning to Hennepin as faculty in 2014, he sees patients in the ED and the MICU, directs the ECMO program at HCMC, and is a clinical investigator including service on the Executive Committee of the Pragmatic Critical Care Research Group studying interventions in the ED and ICU including emergency airway mangement and ECMO.

Bio

Administrator Info
Name: Karen Fitz
Email: fitz0355@umn.edu
Mail: 420 Delaware Street SE, MMC 480, Minneapolis, MN 55455
Summary
Clinically Dr. Premnath focuses on myeloid malignancies and a premalignant condition called clonal hematopoiesis of indeterminate potential. Having completed training in palliative care in addition to hematology/oncology, a main focus of his research has been supportive care for cancer patients as well as other aspects of cancer care like financial toxicity that matter most to patients and caregivers. He is actively involved in clinical research in the myeloid realm and has recently had a Phase 1 trial approved in MDS/AML. He looks forward to starting a clonal hematopoiesis focused clinic and a biobank as part of that effort.
Awards and Recognition Received
Conquer Cancer Merit Award - ASCO Annual Meeting 05/2023
Fellowship Research Award- UTSW Medical Center in 2022 & 2023
TxSCO Outstanding Fellows Abstract Award 10/2021
Professional Memberships and Affiliations
American Society of Hematology
American Society of Oncology
American association for cancer research
Clinical Title
Hematologist; Oncologist
Research Interests
MDS/AML 
CHIP 
Supportive care 
Phase 1 trials
Clinical Interests
MDS 
AML 
CHIP 
MPN 
CML 
Academic Interests
Translational research
Pallonc
Supportive care 

Board Certifications:
Hematology
American Board of Internal Medicine, 2023

Oncology
American Board of Internal Medicine, 2023

Hospice and Palliative Medicine
American Board of Internal Medicine, 2022

Internal Medicine
American Board of Internal Medicine, 2021
Preferred Pronouns
He/Him

Bio

Administrator Info
Name: Lisa Moe
Phone:
Email: seif0046@umn.edu
Fax: 
Mail: Cancer & Cardiovascular Research Building
Lillehei Heart Institute
1st Floor Mailroom CCRB
2231 6th Street SE
Minneapolis, MN 55455

Summary
Dr. Prins is dedicated to understanding right ventricular (RV) dysfunction in pulmonary hypertension. He studies the RV in clinical studies as well as his basic science laboratory. He has given talks at multiple international conferences and receives grant funding from the NIH. Come work with us! Visit https://med.umn.edu/lhi/about/jobs to see open positions in the Prins lab.

Research Summary

• Pulmonary Hypertension
• Right Ventricular Failure
• CTEPH
• Clinical Trial Participation
• Pulmonary Balloon Angioplasty

Teaching Summary

• Cardiac Physiology

Clinical Summary

CTEPH, Invasive hemodynamics, Pulmonary embolus, Pulmonary artery hypertension, Pulmonary hypertension and right heart failure, Right ventricular dysfunction

Bio

Dr. Prisco is a cardiovascular physician-scientist who specializes in treating pulmonary hypertension. She has a basic science laboratory that investigates mechanisms of right ventricular dysfunction in pulmonary hypertension. She received her M.D. and Ph.D. at the Medical College of Wisconsin. She completed her training in internal medicine and cardiovascular disease at the University of Minnesota through the Physician-Scientist Training Pathway. As a cardiology fellow, she secured a National Institutes of Health postdoctoral grant (NIH F32) and won early career investigator awards from the American Heart Association (AHA), American College of Cardiology, and Northwestern Cardiovascular Young Investigators’ Forum. 

Research Summary

Right Ventricular Failure; Pulmonary Hypertension; Translational Research

Creative Activity Summary

• NIH Mentored Clinical Scientist Research Career Development Award (K08 Grant) (2023-2028)
• American Heart Association Career Development Award (2023-2026)
• American Heart Association Cardiopulmonary, Critical Care, Perioperative and Resuscitation Cournand and Comroe Early Career Investigator Award Winner (2021)
• American College of Cardiology Young Investigator Award Winner in Basic and Translational Science (2021)
• National Institutes of Health Ruth L. Kirschstein Postdoctoral Individual National Research Service Award (F32 Grant) (2021-2022)
• Northwestern Cardiovascular Young Investigators' Forum Winner in Fellows Basic Science (2020)
• National Institutes of Health Ruth L. Kirschstein Institutional National Research Service Award (T32 Grant) (2019-2021)
• University of Minnesota Department of Medicine Peter Bitterman Award for Outstanding Postdoctoral Basic Research (2021)
• University of Minnesota Yang Wang Cardiology Research Fellowship Award (2021)
• University of Minnesota Cecil J. Watson Award (2021); University of Minnesota Cardiovascular Retreat (CardioPalooza) Best Postdoctoral Fellow Oral Presentation (2021)
• University of Minnesota Clinical and Translational Science Institute (CTSI) Translational Research Development Program Grant (2020-2022)

Teaching Summary

Training Future Physicians and Scientists.

Clinical Summary

Pulmonary Hypertension; Right Ventricular Dysfunction

Bio

Administrator Info
Email: cvheart@umn.edu
Mail: 420 Delaware Street SE
MMC 508 Mayo
8508A (Campus Delivery Code)
Minneapolis, MN 55455

Summary
Heart disease is a chronic disease that requires a system of care to provide establisehd treatments and patient education and reinforcement, as well as to use established therapies in new and novel ways, and provide access to new and promising therapies as they emerge. We have a system of care that provides easy access and a team approach to long-term care, patient education, and therapy adjustment.

Clinical Summary

Complex heart disease and disease management; Heart failure; Non-healing wounds; Pulmonary artery hypertension; Heart transplantation and regeneration; Endothelial dysfunction (blood vessel disease); Electrophysiology

Bio

Dr. Pruett began his clinical career at the University of Virginia rising from Assistant Professor of Surgery (1987) to Professor of Surgery and Division Chief of Transplantation Surgery by 1996. He was appointed the Strickler Family Professor of Transplantation in 1997. He was the Program Director of the transplantation training program at University of Virginia. As an intensivist, he was co-director of the surgical ICU and established and was Program Director of the Critical Care Training program. In 2009, he moved to the University of Minnesota as Professor of Surgery and Internal Medicine.

Dr. Pruett is Past-President of American Society of Transplant Surgeons (2016-2017) and previously served as Treasurer of American Society of Transplant Surgeons’ Council (2012-2015). He has served on and chaired various committees within the ASTS and AST and has spoken broadly on legal and system issues that impact to organ transplantation within global healthcare systems. Dr. Pruett was President of United Network for Organ Sharing (2008-2009); Chair of the Membership and Professional Standards Committee (2007- 2008) and has represented UNOS in multiple international initiatives.

Research Summary

Dr. Pruett’s research interests have included organ transplantation in patients with chronic viral diseases, the ethics and practice of live kidney donation and allocation, transmissible diseases through organs and infections after organ transplantation. He also has education and infection interests as they pertain to the care of the critically ill.

Clinical Summary

Kidney Transplant, Liver Transplant, Living Donor Transplant

Bio

In 2014, Dr. Puchalska obtained her PhD degree from the Faculty of Chemistry, Department of Analytical Chemistry and Chemical Engineering at the University of Alcalá (Spain). She joined Dr. Crawford's group in 2015 to exploit the field of mass spectrometry-based metabolomics and lipidomics to study metabolism on a systems level. She joined Division of Molecular Medicine at the University of Minnesota Medical School in 2017, where she leads cutting-edge research that utilizes mass spectrometry approaches to reveal essential information regarding the metabolism. Her research focus is to prevent the progression of nonalcoholic fatty liver disease (NAFLD), which is tightly linked to the obesity and Type 2 Diabetes epidemics increasing in prevalence.

Research Summary

Utilization of mass spectrometry approaches to reveal essential information regarding the metabolism; Prevention of the progression of nonalcoholic fatty liver disease (NAFLD), which is tightly linked to the obesity and Type 2 Diabetes epidemics

Teaching Summary

Mass spectrometry-based metabolomics and lipidomics

Clinical Summary

Non-alcoholic fatty liver disease

Bio

Administrator Info
Name: Admin
Phone: 612-624-9996
Fax: 612-625-4410
Email: idimdivision@umn.edu
Mail: Mayo Memorial Building, MMC 250, 420 Delaware Street S.E., Minneapolis, MN 55455 
 

Summary
Dr. Matthew Pullen completed both his medical education and residency at the University of Tennessee Health Science Center in Memphis, Tennessee, followed by an infectious diseases and international medicine fellowship at the University of Minnesota. Prior to fellowship, his primary areas of research were novel sequencing techniques and group A streptococcus. During fellowship, his research has primarily focused on tuberculosis, cryptococcal meningitis, and COVID-19. He was awarded an NIH Fogarty Global Health Fellowship, allowing him to spend a year working on tuberculosis whole genome sequencing projects in Uganda, as well as performing clinical duties as a consultant and providing medical education lectures.

Research Summary

• Data science
• Epidemiology
• Biodefense

Clinical Summary

COVID-19; Tuberculosis; Cryptococcal meningitis

Bio

Administrator Info
Name: Emily Olmsted-Morales
Phone: 612-624-0999
Email: olmst111@umn.edu
Fax: 612-625-2174

Summary
After receiving my medical degree, I completed my residency in Internal medicine in 2000. During my residency at Howard University, I was exposed to biomedical research and I became interested in pursuing clinical research for a career. However, for immigration reasons, I took a primary care position in a medically underserved rural area for a few years. From there, I became a research fellow in cardiovascular physiology at the Mayo Clinic. After spending two years doing clinical research, I completed a fellowship at the Mayo Clinic in sleep medicine and began to publish research reports. Subsequently, I then took a faculty position at the University of Minnesota in the Division of Pulmonary/Critical Care/Sleep Medicine. Meanwhile, I have continued to collaborate with Dr. Virend Somers at Mayo Clinic. Sleep medicine is a developing field, with ample opportunity for clinical research. Though obstructive sleep apnea's (OSA) significant association with cardiovascular disease is well known, the pathophysiological mechanisms involved remain unclear. My plan is to pursue new biomarkers and other clinical indicators than will permit these pathophysiological mechanisms to become clearer. My aim is then to initiate a clinical research program that will use these biomarkers for early detection and, eventually, treatment of OSA.

Research Summary

Study pertaining to effects of changes in body fat composition on sleep and cardiovascular physiology (Mentor: Somers VK, MD); Study involving the relationship between sleep and acute myocardial infarction (Mentor: Somers VK, MD); Comparative analysis of cardiac inflammatory markers in Asian Indians vs. Caucasians (Mentor: Somers VK, MD)

Minnesota Medical Foundation Pusalavidyasagar (PI) 03/01/12-2/28/14
Determination of Endogenous Levels of Hydrogen Sulfide and Nitric Oxide in patients with Obstructive Sleep Apnea
Role: PI

Bio

Administrator Info
Email: endofixer@umn.edu
Mail: 420 Delaware Street SE
MMC 101
Minneapolis, MN 55455

Summary
Dr. Angela Radulescu graduated from the "Carol Davila" University of Medicine and Pharmacy in Bucharest, Romania. She completed an Internal Medicine Residency at Flushing Hospital, NY, and a Fellowship in Endocrinology at the University of Minnesota. She is the Director of Medical Education for students and residents for the Division of Diabetes & Endocrinology. Her clinical interest include thyroid and adrenal disorders.

Clinical Summary

Thyroid Cancer; Thyroid Disease; Neuroendocrine tumors; Adrenal disorders

Bio

Administrator Info
Name: Admin
Phone: 612-624-9996
Fax: 612-625-4410
Email: idimdivision@umn.edu
Mail: Microbiology Research Building, 1st floor mail room, MMC 2821, 689 SE 23rd Ave, Minneapolis, MN 55455

Summary
Dr. Rajasingham is an Infectious Diseases physician and physician-scientist at the University of Minnesota. Her primary research interest is to maximize the public health impact of screening HIV-infected persons for opportunistic infections in order to decrease HIV/AIDS-related mortality. She is particularly interested in the evaluation of cost-effective diagnostics and treatment algorithms to care of persons with advanced HIV disease. Dr. Rajasingham is the co-PI of a phase II randomized clinical trial in Uganda evaluating the safety of high dose AmBisome to prevent cryptococcal meningitis in persons with advanced HIV disease, and PI for an R01 cluster-randomized trial evaluating point-of-care diagnostics in persons with advanced HIV disease, funded by NIAID. 

Research Summary

Dr. Rajasingham is a physician-scientist trained in the clinical practice of infectious diseases. Her research interests span evaluation and cost-effectiveness of point-of-care diagnostics in persons with advanced HIV disease, cryptococcal screening and prevention, and management of cryptococcal meningitis.

Research Projects

• Evaluation of CRAG Screening with Enhanced Antifungal Therapy for Asymptomatic CRAG-Positive Persons (K23AI138851)
• An Enhanced Package of Care to Reduce Mortality in Persons with Advanced HIV Disease (R01AI162181)

Clinical Summary

• HIV/AIDS
• PREP
• Global Health

Bio

Michael Raleigh is an Assistant Professor in the Department of Pharmacology. He received his BS degree with distinction from the University of Minnesota in 2006. He worked at a small biotech company in Chaska MN before pursuing his PhD. His professional training began in graduate school at the University of Minnesota in the laboratory of Dr. Paul Pentel studying the efficacy of heroin and oxycodone vaccines to block opioid-induced effects. During this time, he collaborated with Dr. Benito Anton (National Institute of Psychiatry, Mexico), studying the efficacy of their heroin vaccine. Due to the rise of the opioid epidemic and the potential application of these vaccines as treatments for opioid addiction, he continued his postdoctoral work at Hennepin Healthcare Research Institute studying the behavioral effects of these vaccines. He currently works alongside Dr. Marco Pravetoni at UMN to lead IND-enabling studies for use of opioid vaccines in clinical studies. His independent research interest focuses on countermeasures to reduce opioid toxicity and overdose.

Research Summary

Opioid use has increased markedly over the years, leading to an opioid epidemic in the US. Furthermore, because fentanyl and fentanyl analogs are easy to manufacture and are extremely potent, they are increasingly found in adulterated counterfeit medications and illicit drugs, leading to an increase in opioid toxicity and overdose deaths in the US. Dr. Raleigh's research interest is in studying therapies to treat opioid use disorders and toxicity related to their use. These therapies include vaccines, monoclonal antibodies, and small molecule interventions. Combining these various interventions, along with currently approved therapies, could improve outcomes for patients seeking treatment for an opioid use disorder or help prevent or reverse opioid-induced toxicity and overdose.

Bio

Dr. Ramu is an Advanced Heart Failure & Transplant Cardiologist, with additional expertise in Cardio-Obstetrics and Cardio Oncology. She is being recruited from the Medical University of South Carolina where she served as Director of Cardio-Oncology and Co-Medical Director of the Cardiovascular ICU. In her new role at the University of Minnesota, she will serve as the Director of Cardio-Obstetrics program apart from continuing her Advanced heart failure and Cardio-Oncology practice. Dr. Ramu’s research interests include increasing the understanding of and reducing the impact of health-related disparities in patients with advanced heart failure, with a goal of reducing health inequities and improving the health of disadvantaged and vulnerable populations. This research spans the fields of advanced heart failure, Cardio-Obstetrics and Cardio-Oncology.

Research Summary

Health related disparities in advanced heart failure, Cardio-Obstetrics, Cardio-Oncology

Creative Activity Summary

• American College of Cardiology's Emerging Faculty 2022
• ISHLT's 2022 Cardiology Professional Community Award for Excellence
• MUSC's John R. Raymond Mentoring Fellowship Award 2022; Highest patient satisfaction scores

Teaching Summary

 Teaching and mentoring trainees, Women in Cardiology

Service Summary

• American College of Cardiology
• American Heart Association
• Heart Failure Society of America
• International Society of Heart & Lung Transplantation
• American Society of Transplantation
• Women in Heart Transplant & Mechanical Circulatory Support

Clinical Summary

Advanced heart failure, Cardio-Obstetrics, Cardio-Oncology

Bio

Administrator Info
Email: gimadmin@umn.edu
Mail: 420 Delaware ST SE
MMC 741
Minneapolis, MN 55455

Summary
Dr. Ratner received his undergraduate degree from Carleton College. Medical school and residency training in Internal Medicine were at University of Chicago and affiliate hospitals. Post-residency training in Geriatric Medicine has included the Harvard's Geriatric Education Center, the Home Medicine Program at Boston University, and the University of Minnesota's Internal Medicine Geriatric Fellowship. His clinical practice currently focuses on care in the home, on behalf of the Spinal Cord Injury and Disorders Program of the Minneapolis VA Medical Center. He serves on the Graduate faculty in three programs: Bioethics, Gerontology and Health Informatics. Research and teaching interests include bioethics, home care, interprofessional education, end of life care, and ALS. His current projects include an AHRQ funded study of decision aids in advance care planning, development of a statewide POLST form and creation of service learning opportunities for medical and other graduate students.

Research Summary

Home Health, Telemedicine, End of Life Care, Geriatrics

Bio

Administrator Info
Name: Krista Ostrom
Email: kostrom@umn.edu
Mail: 420 Delaware Street SE
MMC 508 Mayo
8508A (Campus Delivery Code)
Minneapolis, MN 55455

Summary
A graduate of the University of Minnesota's general- and interventional-cardiology fellowship programs, Dr. Ganesh Raveendran joined the faculty in 2005 after practicing at Mayo Clinic in Rochester, Minnesota. In addition to interventional cardiology, Dr. Raveendran is board-certified in critical care medicine. Raveendran's clinical interests include diagnostic and interventional cardiac catheterization in critical-care and other high-risk patients, minimally-invasive closure of congenital heart defects in adults, prosthetic implantation for valvular heart disease, and balloon pulmonary angioplasty.Raveendran is currently Chief of Clinical Cardiology, Director of Interventional Cardiology and Director of the Interventional and Structural Heart Disease Fellowship programs.

Clinical Summary

Interventional cardiology; Invasive hemodynamics; Percutaneous closure of patent foramen ovale and atrial septal defect; Coronary physiology; Coronary artery disease; Vascular biology; Premature atherosclerosis

Bio

Administrator Info
Name: Audra Field
Phone: 612-626-3003
Email: afield@umn.edu
Fax: 612-625-6919
Mail: 420 Delaware Street SE
MMC 480
Minneapolis, MN 55455

Summary
Dr. Reding received his M.D. in 1992 from the University of Minnesota. He also completed residency training in Internal Medicine and subspecialty training in Hematology/Oncology at the University of Minnesota. He is board certified in both Hematology and Medical Oncology.

Clinical Summary

Bleeding and clotting disorders, Hemophilia