'Rescue Study’ Analyzes if a Protective Substance in the Blood Vessels Can Impact COVID Infections
Marc Pritzker, MD, FACC, professor in the Department of Medicine’s Cardiovascular Division, is a primary investigator for the study. Dr. Pritzker is working in tandem with co-investigators Craig Weinert, MD, MPH, professor, and Hem Desai, MBBS, MPH, assistant professor, both in the Department of Medicine’s Division of Pulmonary, Allergy, Critical Care and Sleep Medicine. (Jan. 2021)
New clinical trial uses CAR NK cells derived from human induced pluripotent stem cells (iPSC) as a renewable cell source for product manufacture and off-the-shelf delivery to patients.
Principal Investigator, Veronika Bachanova, MD, PhD, Professor of Medicine at the Medical School and Lead of the Lymphoma Interdisciplinary Team.
The multi-centered trial is investigating the safety and activity of the universal, off-the-shelf NK cell product, and builds off of the groundbreaking NK research done by Jeffrey Miller, MD, Deputy Director of the Masonic Cancer Center and Professor of Medicine at the University of Minnesota Medical School. (Jan. 2021)
Meet the Inaugural Vice Dean of Diversity, Equity and Inclusion
Ana Núñez, MD, FACP, estimates meeting 600-700 people in her first few months as the inaugural vice dean for diversity, equity and inclusion (DEI) at the University of Minnesota Medical School. She is also a Professor of Medicine in the Division of General Internal Medicine ∙ Biography (Dec. 2020)
Elected as a Distinguished Fellow or the National Academies of Practice
Brian Sick, MD was elected as a Distinguished Fellow or the National Academies of Practice. The requirements for membership are people who have an exemplary career of ten years or more and who have made significant contributions to interprofessional healthcare. He is also an Associate Professor of Medicine and Division Director of General Internal Medicine. (Dec. 2020)
Congratulations Dr. Sick!
New Healthcare Disparities Grant
Taj Mustapha, MD, assistant professor in the Departments of Medicine and Pediatrics, is studying how unfairness manifests during medical training, where it is prevalent and who is most affected. The research will build a tool to better measure how fairness impacts learners from typically underrepresented backgrounds. (Nov. 2020)
Medicine Faculty Named on the 2020 Highly Cited Researchers List
|Dr. Alexander Khoruts
Professor of Medicine
Dr. Bertram Kasiske
Professor of Medicine
World’s First ECMO-based Clinical Trial Shows 6 Times Higher Survival Rates
A team led by Demetri Yannopoulos, MD has published the results of the first ECMO-based clinical trial in the world. The trial has shown a 6x increase in survival rate among patients experiencing cardiac arrest who received treatment from the life-support machine known as ECMO (extracorporeal membrane oxygenation).
Experimental hormone therapy may speed recovery for COVID patients
David Ingbar, MD, Professor of Medicine in the Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, is featured as the lead story in the Star Tribune.
Dr. Ingbar had studied for years whether a common thyroid hormone could be repurposed for the treatment of acute respiratory distress syndrome (ARDS), an often fatal type of lung failure. Federal approval was granted late last year to test the therapy, so when COVID-19 caused a sudden surge in ARDS, they were ready for their first patient.
Prisco Wins First from NCYIC
Medical Fellow Sasha Prisco of the Prins lab has earned first place in the Northwestern Cardiovascular Young Investigator Competition for her entry titled "GP130 Signaling Promotes Right Ventricular Dysfunction in Pulmonary Arterial Hypertension."
New $500K Grant Supports Hormone Receptor Research in Metastatic Breast Cancer
A significant grant from METAvivor worth $500,000 over three years will allow Carol Lange, PhD, a professor in the Department of Medicine, Division of Hematology, Oncology & Transplantation, to analyze the biological mechanisms behind breast cancer, particularly how steroid hormone receptors impact the disease.
ASN Members Elect Newest At-Large Councilor, Patrick H. Nachman
Dr. Nachman, Professor of Medicine and Division Director, Nephrology and Hypertension, will begin his term on Friday, January 1, 2021, and will serve through Tuesday, December 31, 2024.
Congratulations Dr. Nachman!
How to turn your Research Discovery into an Eye-catching Piece of Cover Art
Cynthia Faraday, graphic designer and media artist at the Lillehei Heart Institute at the University of Minnesota was quoted in CellPress.
"The process is actually a lot easier with scientists who are super excited about what they’re doing. Because when they’re super excited and they think what they’re doing is beautiful and amazing, it makes it easier for me to make it beautiful and amazing."
USING SCIENCE TO FIND SOLUTIONS
Dr. Susan Kline, professor of Medicine with the division of Infectious Diseases & International Medicine and an Epidemiologist for M Health Fairview, U of Minnesota Medical Center
In the wake of an Ebola outbreak five years ago in West Africa, 10 regional treatment centers in the United States with expertise in special pathogens developed a research network to study treatments for emerging infectious diseases. Epidemiologist Dr. Susan Kline led the University of Minnesota Medical Center team in Minneapolis, which contributed to a key study this spring of the drug remdesivir. Results from the treatment centers, combined with other study sites, give hope that some COVID-19 patients will see shorter hospital stays with remdesivir, a drug that previously was studied for Ebola patients. “When these infectious disease emergencies happen,” Kline said, “you’re going to learn more about the drugs and whether they’re efficacious against these novel pathogens if you have the strength of a research network.”
— Christopher Snowbeck
Team Helps Develop World’s First AI-Controlled CPR System
A team at the University of Minnesota Medical School and the Georgia Institute of Technology has invented the world’s first artificial intelligence (AI) closed-loop CPR system. Early studies show the system performs better than both a licensed physician and the LUCAS machine during cardiac arrest.
Ronald Reilkoff, MD, Assistant Professor in the Department of Medicine, Division of Pulmonary, Allergy, Critical Care & Sleep Medicine, has overseen the development and implementation of a virtual curriculum that mimics the experience a fourth-year medical student would have in the ICU during an in-person clerkship.
Assistant Professor Earns 2020 Clinical Scientist Development Award
Forum Kamdar, MD, FACC, in the Department of Medicine is one of 17 physician scientists in the U.S. to receive a $495,000 award from the Doris Duke Charitable Foundation to expand on her research that hopes to improve therapy for those with Duchenne muscular dystrophy.
Teaching Medical Students how to Combat Misinformation on Social Media
Kristina Krohn, MD, Assistant Professor with the division of General Internal Medicine, started a four-week course that teaches medical students how to use social media and their medical education to connect others with timely and accurate public health information online during the COVID-19 pandemic.
Bong Sook Jhun, PhD, FCVS, leads U of M team of researchers in examining the protective role that common PDE5 inhibitor medications might play during COVID-19 infection. If proven, these medications could potentially lead to milder symptoms, fewer hospitalizations, and quicker recoveries in COVID-19 patients with pre-existing heart and lung diseases.
Dr. Bong Sook Jhun, Assistant Professor of Medicine with the Division of Cardiovasular
Promising Treatment to Slow Kidney Disease Doesn’t Prove Out in Clinical Trial
Michael Mauer, MD, professor in the Departments of Pediatrics and Medicine and kidney specialist at the University of Minnesota Medical School, and his colleagues conducted an international, multi-institution, randomized clinical trial that enrolled 530 participants to study whether allopurinol would slow the disease.
How to Protect Against Current, Future Strains of the Coronavirus
A new vaccine development approach, now being studied at the University of Minnesota Medical School, hopes to protect against current and future strains of SARS-CoV-2 (COVID-19).
“This virus is affecting the whole world, and we’re not able to respond fast enough to thwart it with a vaccine,” said Geoffrey Hart, PhD, assistant professor in the Department of Medicine, who leads the project. “Our hope is that the first wave of vaccines that other teams are working on will protect against SARS-CoV-2, and then our next-generation universal vaccine or antibodies would protect against future variants of SARS-CoV.”