White Matter Structure/Function in Diabetes

This Study aims to investigate the effects of diabetes and its treatments on brain metabolism and function. Diabetes mellitus is a complex disease that affects many, if not all, of the organs in the body. The leading cause of end stage kidney disease in the United States, diabetes is also a common cause of vision loss, nerve problems, and heart disease. Whether diabetes has an effect on the central nervous system was uncertain for many years, but as patients with diabetes live longer and better with the disease, the consequences of diabetes on the brain are now becoming apparent. Both the high blood sugar and the low blood sugar associated with diabetes treatment have been thought to alter the structure and function of the brain. It is the goal of this project to determine the effects of diabetes on the brain.

Are you eligible to participate?

You may be eligible to participate in this Study if you:

  • Are over the age of 18
  • Have Type 1 diabetes for more than 25 years

This study is also accepting healthy participants.

What is involved in the Study?

Participants with diabetes and healthy participants will be asked to visit the University of Minnesota twice (2) for approximately 2 ½ hours each time.

  • 1st visit – Blood sugar will be measured and a blood sample taken. A series of mental test designed to measure memory and the ability to process information will be given.
  • 2nd visit – Blood sugar will be measured and a blood sample taken. A brain scan in an MRI machine will be preformed.