Sarah Zaghouani

UMN MSTP student Sarah Zaghouani

Email: zagho001@umn.edu

Entering Class: 2021

Education: 
Harvard University
Human Developmental and Regenerative Biology major, Language Citation in Modern Arabic (minor)
B.A., 2016

Sarah is currently in the second year of Medical School training and rotating through labs in preparation for selecting a thesis advisor.

 

Publications:

Work done prior to the UMN MSTP:

Wagner A, Wang C, Fessler J, DeTomaso D, Avila-Pacheco J, Kaminski J, Zaghouani S, Christian E, Thakore P, Schellhaass B, Akama-Garren E, Pierce K, Singh V, Ron-Harel N, Douglas VP, Bod L, Schnell A, Puleston D, Sobel RA, Haigis M, Pearce EL, Soleimani M, Clish C, Regev A, Kuchroo VK, Yosef N. Metabolic modeling of single Th17 cells reveals regulators of autoimmunity. Cell. 2021 Jun 29:S0092-8674(21)00700-5. Online ahead of print.

Zhu C, Dixon KO, Newcomer K, Gu G, Xiao S, Zaghouani S, Schramm MA, Wang C, Zhang H, Goto K, Christian E, Rangachari M, Rosenblatt-Rosen O, Okada H, Mak T, Singer M, Regev A, Kuchroo V. Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion. Sci Adv. 2021 Apr 30;7(18):eabd2710. PMCID: PMC8087420

Zhu C, Sakuishi K, Xiao S, Sun Z, Zaghouani S, Gu G, Wang C, Tan DJ, Wu C, Rangachari M, Pertel T, Jin HT, Ahmed R, Anderson AC, Kuchroo VK. An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nat Commun. 2015 Jan 23;6:6072. PMCID: PMC4311884

Zhu C, Sakuishi K, Xiao S, Sun Z, Zaghouani S, Gu G, Wang C, Tan DJ, Wu C, Rangachari M, Pertel T, Jin HT, Ahmed R, Anderson AC, Kuchroo VK. Corrigendum: An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nat Commun. 2015 Jul 8;6:7657.

Cascio JA, Haymaker CL, Divekar RD, Zaghouani S, Khairallah MT, Wan X, Rowland LM, Dhakal M, Chen W, Zaghouani H. Antigen-specific effector CD4 T lymphocytes school lamina propria dendritic cells to transfer innate tolerance. J Immunol. 2013 Jun 15;190(12):6004-14. PMCID: PMC3679289

Wan X, Guloglu FB, Vanmorlan AM, Rowland LM, Zaghouani S, Cascio JA, Dhakal M, Hoeman CM, Zaghouani H. Recovery from overt type 1 diabetes ensues when immune tolerance and β-cell formation are coupled with regeneration of endothelial cells in the pancreatic islets. Diabetes. 2013 Aug;62(8):2879-89. PMCID: PMC3717841

Haymaker CL, Guloglu FB, Cascio JA, Hardaway JC, Dhakal M, Wan X, Hoeman CM, Zaghouani S, Rowland LM, Tartar DM, VanMorlan AM, Zaghouani H. Bone marrow-derived IL-13Rα1-positive thymic progenitors are restricted to the myeloid lineage. J Immunol. 2012 Apr 1;188(7):3208-16. PMCID: PMC3311706


CONTACT MEDICAL SCIENTIST TRAINING PROGRAM (MD/ PhD)

B681 Mayo Building, MMC 293
420 Delaware St. SE, Minneapolis, MN 55455

Email: mdphd@umn.edu
Phone: 612-625-3680 | Fax: 612-626-5994