Adrina Kocharian

UMN MSTP student Adrine Kocharian

Email: kocha048@umn.edu

Entering class: 2017

Education:  
University of California, Los Angeles
Neuroscience major
B.S., 2014

Honors and Awards:

  • Ruth L. Kirschstein National Research Service Award for Predoctoral MD/PhD Fellows, National Institute of Mental Health, 2021-2025

MSTP Student Governance:

  • Student Advisory Committee, 2020-2022 (co-chair 2020-2021, chair 2021-2022)

Thesis Advisors: Patrick Rothwell, Ph.D. and David Redish, Ph.D.

Thesis Research

The neural correlates of decision-making.

Publications (pubmed)

Trieu BH, Remmers BC, Toddes C, Brandner DD, Lefevre EM, Kocharian A, Retzlaff CL, Dick RM, Mashal MA, Gauthier EA, Xie W, Zhang Y, More SS, Rothwell PE. Angiotensin-converting enzyme gates brain circuit-specific plasticity via an endogenous opioid. Science. 2022 Mar 11;375(6585):1177-1182. PMCID: PMC9233526

Work prior to the UMN MSTP:

Halladay LR, Kocharian A, Piantadosi PT, Authement ME, Lieberman AG, Spitz NA, Coden K, Glover LR, Costa VD, Alvarez VA, Holmes A. Prefrontal Regulation of Punished Ethanol Self-administration. Biol Psychiatry. 2019 Nov 13. [Epub ahead of print]

Radke AK, Kocharian A, Covey DP, Lovinger DM, Cheer JF, Mateo Y, Holmes A. Contributions of nucleus accumbens dopamine to cognitive flexibility. Eur J Neurosci. 2019 Aug;50(3):2023-2035.

Jury NJ, Radke AK, Pati D, Kocharian A, Mishina M, Kash TL, Holmes A. NMDA receptor GluN2A subunit deletion protects against dependence-like ethanol drinking. Behav Brain Res. 2018 Nov 1;353:124-128. PMCID: PMC6092743

Halladay LR, Kocharian A, Holmes A. Mouse strain differences in punished ethanol self-administration. Alcohol. 2017 Feb;58:83-92. PMCID: PMC6060418

Gamble-George JC, Baldi R, Halladay L, Kocharian A, Hartley N, Silva CG, Roberts H, Haymer A, Marnett LJ, Holmes A, Patel S. Cyclooxygenase-2 inhibition reduces stress-induced affective pathology. Elife. 2016 May 10;5. pii: e14137. PMCID: PMC48062754

Radke AK, Jury NJ, Kocharian A, Marcinkiewcz CA, Lowery-Gionta EG, Pleil KE, McElligott ZA, McKlveen JM, Kash TL, Holmes A. Chronic EtOH effects on putative measures of compulsive behavior in mice. Addict Biol. 2017 Mar;22(2):423-434. PMCID: PMC4916036

Mineharu Y, Muhammad AK, Yagiz K, Candolfi M, Kroeger KM, Xiong W, Puntel M, Liu C, Levy E, Lugo C, Kocharian A, Allison JP, Curran MA, Lowenstein PR, Castro MG. Gene therapy-mediated reprogramming tumor infiltrating T cells using IL-2 and inhibiting NF-κB signaling improves the efficacy of immunotherapy in a brain cancer model. Neurotherapeutics. 2012 Oct;9(4):827-43. PMCID: PMC3480576