Anja M. Touma
Email: touma@umn.edu
Entering Class: 2015
Education:
Gustavus Adolphus College
Biochemistry and Molecular Biology major
B.A., 2012
MSTP Student Governance:
- Student Advisory Committee, 2015-2017
Honors and Awards:
- Ruth L. Kirschstein National Research Service Award for Predoctoral MD/PhD Fellows, National Heart, Lung, and Blood Institute, 2019-2023
Thesis Advisor: Sivaraj Sivaramakrishnan, Ph.D.
Publications:
For work prior to the MSTP
Swenson AM, Tang W, Blair CA, Fetrow CM, Unrath WC, Previs MJ, Campbell KS, Yengo CM. Omecamtiv Mecarbil Enhances the Duty Ratio of Human β-Cardiac Myosin Resulting in Increased Calcium Sensitivity and Slowed Force Development in Cardiac Muscle. J Biol Chem. 2017 Mar 3;292(9):3768-3778. PMCID: PMC5339759
Trivedi DV, Muretta JM, Swenson AM, Davis JP, Thomas DD, Yengo CM. Direct measurements of the coordination of lever arm swing and the catalytic cycle in myosin V. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14593-8. PMCID: PMC4664342
Swenson AM, Trivedi DV, Rauscher AA, Wang Y, Takagi Y, Palmer BM, Málnási-Csizmadia A, Debold EP, Yengo CM. Magnesium modulates actin binding and ADP release in myosin motors. J Biol Chem. 2014 Aug 22;289(34):23977-91. PMCID: PMC4156094
Trivedi DV, Muretta JM, Swenson AM, Thomas DD, Yengo CM. Magnesium impacts myosin V motor activity by altering key conformational changes in the mechanochemical cycle. Biochemistry. 2013 Jul 9;52(27):4710-22. PMCID: PMC3855573