Christopher G. Tucker

Christopher Tucker


Entering Class:


University of Oregon
Biology major, Biochemistry minor
B.S., 2009

University of Minnesota
Microbiology, Immunology and Cancer Biology Graduate Program
Ph.D., 2020

MSTP Student Governance:

  • Student Advisory Committee 2019-2021

Thesis Avisor: Brian Fife, Ph.D.

Publications (pubmed)


Dwyer AJ, Ritz JM, Mitchell JS, Martinov T, Alkhatib M, Silva N, Tucker CG, Fife BT. Enhanced CD4+ and CD8+ T cell infiltrate within convex hull defined pancreatic islet borders as autoimmune diabetes progresses. Sci Rep. 2021 Aug 25;11(1):17142. PMCID: PMC8387412

Tucker CG, Dwyer AJ, Fife BT, Martinov T. The Role of Programmed Death-1 in Type 1 Diabetes. Curr Diab Rep. 2021 May 6;21(6):20. PMCID: PMC8323125

Williams JW, Zaitsev K, Kim KW, Ivanov S, Saunders BT, Schrank PR, Kim K, Elvington A, Kim SH, Tucker CG, Wohltmann M, Fife BT, Epelman S, Artyomov MN, Lavine KJ, Zinselmeyer BH, Choi JH, Randolph GJ. Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression. Nat Immunol. 2020 Oct;21(10):1194-1204. PMCID: PMC7502558

Tucker CG, Mitchell JS, Martinov T, Burbach BJ, Beura LK, Wilson JC, Dwyer AJ, Singh LM, Mescher MF, Fife BT. Adoptive T Cell Therapy with IL-12-Preconditioned Low-Avidity T Cells Prevents Exhaustion and Results in Enhanced T Cell Activation, Enhanced Tumor Clearance, and Decreased Risk for Autoimmunity. J Immunol. 2020 Sep 1;205(5):1449-1460. PMCID: PMC8293279

Martinov T, Swanson LA, Breed ER, Tucker CG, Dwyer AJ, Johnson JK, Mitchell JS, Sahli NL, Wilson JC, Singh LM, Hogquist KA, Spanier JA, Fife BT. Programmed Death-1 Restrains the Germinal Center in Type 1 Diabetes. J Immunol. 2019 Aug 15;203(4):844-852. PMCID: PMC7083260

Osum KC, Burrack AL, Martinov T, Sahli NL, Mitchell JS, Tucker CG, Pauken KE, Papas K, Appakalai B, Spanier JA, Fife BT. Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes. Sci Rep. 2018 May 29;8(1):8295. PMCID: PMC597412

Work prior to the UMN MSTP:

Triplett TA, Tucker CG, Triplett KC, Alderman Z, Sun L, Ling LE, Akporiaye ET, Weinberg AD. STAT3 Signaling Is Required for Optimal Regression of Large Established Tumors in Mice Treated with Anti-OX40 and TGFβ Receptor Blockade. Cancer Immunol Res. 2015 May;3(5):526-35.

Kovacsovics-Bankowski M, Chisholm L, Vercellini J, Tucker CG, Montler R, Haley D, Newell P, Ma J, Tseng P, Wolf R, Vetto JT, Hammill C, Hansen P, Weinberg AD. Detailed characterization of tumor infiltrating lymphocytes in two distinct human solid malignancies show phenotypic similarities. J Immunother Cancer. 2014 Nov 18;2(1):38. PMCID: PMC4247679