Erik B. Faber

UMN MSTP student Erik Faber

Email: faber053@umn.edu

Entering Class: 2015

Education:
Dartmouth College
Biophysical Chemistry major, English minor
B.A., 2013

Dartmouth College
Chemistry
M.S., 2014

University of Minnesota
Medicinal Chemistry Graduate Program
Ph.D., 2021

Honors and Awards:

  • Ruth L. Kirschstein National Research Service Award for Predoctoral MD/PhD Fellows, National Cancer Institute, 2019-2022

MSTP Student Governance:

  • Student Advisory Committee, 2015-16
  • Student Admissions and Recruitment Committee, 2017-20

Thesis Advisor: Gunda Georg, Ph.D.

Publications (pubmed

Faber EB, Georg GI. DFG-1 Binding: A New Residue for Developing Selective Kinase Inhibitors. J Med Chem. 2020 Sep 24;63(18):10221-10223.

Faber EB, Wang N, Georg GI. Review of rationale and progress toward targeting cyclin-dependent kinase 2 (CDK2) for male contraception†. Biol Reprod. 2020 Aug 4;103(2):357-367. PMCID: PMC7523694

Shukla DM, Faber EB, Sick B. Defining and Characterizing Frequent Attenders: Systematic Literature Review and Recommendations. J Patient Cent Res Rev. 2020 Jul 27;7(3):255-264. PMCID: PMC7398628

Faber EB, Tian D, Burban D, Levinson NM, Hawkinson JE, Georg GI. Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2. ACS Chem Biol. 2020 Jul 17;15(7):1759-1764.

Wang N*, Faber EB*, Georg GI. Synthesis and Spectral Properties of 8-Anilinonaphthalene-1-sulfonic Acid (ANS) Derivatives Prepared by Microwave-Assisted Copper(0)-Catalyzed Ullmann Reaction. ACS Omega. 2019 Oct 28;4(19):18472-18477. PMCID: PMC6844090 *Co-first authors

Lake EW, Muretta JM, Thompson AR, Rasmussen DM, Majumdar A, Faber EB, Ruff EF, Thomas DD, Levinson NM. Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states. Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11894-E11903. PMCID: PMC6304972

For work prior to the MSTP: 

Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, Ordóñez-Gutiérrez L, Wandosell F, Viña J, Dotti CG, Hall RA, Pulido R, Gerges NZ, Chan AM, Spaller MR, Serrano M, Venero C, Esteban JA. PTEN recruitment controls synaptic and cognitive function in Alzheimer's models. Nat Neurosci. 2016 Mar;19(3):443-53.