Megan M. Schmit

Megan Schmit

Email: schm4097@umn.edu

Entering Class: 2015

Education:
University at Buffalo -SUNY
Biotechnology and Chemistry majors, French minor
B.A./B.S., 2015

MSTP Student Governance:

  • Student Advisory Committee, 2020-2021


Thesis Advisor: Anja Bielinsky, Ph.D.

Thesis Research

Role of replication initiation factors in natural killer cell deficiency.

Publications

Schmit M, Bielinsky AK. Congenital Diseases of DNA Replication: Clinical Phenotypes and Molecular Mechanisms. Int J Mol Sci. 2021 Jan 18;22(2):911. PMCID: PMC781139

Baxley RM, Leung W, Schmit MM, Matson JP, Yin L, Oram MK, Wang L, Taylor J, Hedberg J, Rogers CB, Harvey AJ, Basu D, Taylor JC, Pagnamenta AT, Dreau H, Craft J, Ormondroyd E, Watkins H, Hendrickson EA, Mace EM, Orange JS, Aihara H, Stewart GS, Blair E, Cook JG, Bielinsky AK. Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening. Nat Commun. 2021 Mar 12;12(1):1626. PMCID: PMC7955084

Mace EM, Paust S, Conte MI, Baxley RM, Schmit MM, Patil SL, Guilz NC, Mukherjee M, Pezzi AE, Chmielowiec J, Tatineni S, Chinn IK, Akdemir ZC, Jhangiani SN, Muzny DM, Stray-Pedersen A, Bradley RE, Moody M, Connor PP, Heaps AG, Steward C, Banerjee PP, Gibbs RA, Borowiak M, Lupski JR, Jolles S, Bielinsky AK, Orange JS. Human NK cell deficiency as a result of biallelic mutations in MCM10. J Clin Invest. 2020 Oct 1;130(10):5272-5286. PMCID: PMC7524476