SONIC Lab - Advancing Tinnitus Treatment through Bimodal Neuromodulation
The SONIC Lab has pioneered groundbreaking animal studies demonstrating that neural beamforming (mSync), leveraging just two sensory inputs—sound and body stimulation—can induce significant plasticity in the auditory system. This discovery has profound implications for tinnitus treatment and led to the development of Lenire (Neuromod Devices), the first and only FDA-approved bimodal neuromodulation device for tinnitus. Supported by three clinical trials involving over 500 patients, Lenire has demonstrated exceptional safety, efficacy, and patient compliance, with no device-related adverse events reported. The recent publication of the TENT-A3 (Treatment Evaluation of Neuromodulation for Tinnitus – Stage A3) clinical trial results in Nature Communications highlights the real-world evidence from 204 patients, further validating this approach.
Building on this success, the SONIC Lab is now advancing tinnitus treatment through a holistic, whole-health approach that integrates cutting-edge science with patient-centered care. This includes developing personalized therapies guided by biomarkers, such as heart rate, stress level, to tailor interventions for individual patients. Additionally, we are exploring the integration of complementary integrative health practices, such as deep breathing, reflective journaling, and health coaching, to enhance the overall efficacy of neuromodulation therapies.
To further strengthen our research and clinical impact, we are building collaborations with audiologists and healthcare providers across Minnesota. These partnerships aim to create a larger, more diverse patient cohort, enabling us to investigate the multifaceted nature of tinnitus. By addressing not only biological factors but also mental health, spiritual well-being, and socioeconomic influences, we aim to develop a comprehensive framework for tinnitus care. This multidisciplinary approach will help us better understand the complex interplay of factors contributing to tinnitus and pave the way for more effective, individualized treatment strategies.
