Recent Notable Works from SCI Faculty

Stem Cell Institute faculty collaborate across departments and colleges on basic stem cell biology, cancer biology, and translational research.  The circles on the image above represent individual SCI faculty, color-coded by department, and the interconnections illustrate our collaborative network.

Recent Notable Publications

Generation of human endothelium in pig embryos deficient in ETV2. (2020) Das S, Koyano-Nakagawa N, Gafni O, Maeng G, Singh BN, Rasmussen T, Pan X, Choi KD, Mickelson D, Gong W, Pota P, Weaver CV, Kren S, Hanna JH, Yannopoulos D, Garry MG, Garry DJ. Nat Biotechnol. 38(3):297-302. doi: 10.1038/s41587-019-0373-y. Link

Mitochondrial Defects Drive Degenerative Retinal Diseases. (2020) Ferrington DA, Fisher CR, Kowluru RA. Trends Mol Med. 26(1):105-118. doi: 10.1016/j.molmed.2019.10.008. Link

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function. (2020) Field CS, Baixauli F, Kyle RL, Puleston DJ, Cameron AM, Sanin DE, Hippen KL, Loschi M, Thangavelu G, Corrado M, Edwards-Hicks J, Grzes KM, Pearce EJ, Blazar BR, Pearce EL. Cell Metab. 31(2):422-437.e5. doi: 10.1016/j.cmet.2019.11.021. Link

Failure of intrathecal allogeneic mesenchymal stem cells to halt progressive demyelination in two boys with cerebral adrenoleukodystrophy. (2020) Gupta A, Orchard PJ, Miller WP, Nascene DR, Raymond GV, Loes DJ, McKenna DH, Lund TC. Stem Cells Transl Med. doi: 10.1002/sctm.19-0304. Link

Stem Cell-Derived Cardiomyocytes and Beta-Adrenergic Receptor Blockade in Duchenne Muscular Dystrophy Cardiomyopathy. (2020) Kamdar F, Das S, Gong W, Klaassen Kamdar A, Meyers TA, Shah P, Ervasti JM, Townsend D, Kamp TJ, Wu JC, Garry MG, Zhang J, Garry DJ. J Am Coll Cardiol. 75(10):1159-1174. doi: 10.1016/j.jacc.2019.12.066. Link

Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells. (2020) Koga T, Chaim IA, Benitez JA, Markmiller S, Parisian AD, Hevner RF, Turner KM, Hessenauer FM, D'Antonio M, Nguyen ND, Saberi S, Ma J, Miki S, Boyer AD, Ravits J, Frazer KA, Bafna V, Chen CC, Mischel PS, Yeo GW, Furnari FB. Nat Commun. 11(1):550. doi: 10.1038/s41467-020-14312-1. Link

Cryopreservation of Human iPS Cell Aggregates in a DMSO-Free Solution-An Optimization and Comparative Study. (2020) Li R, Hornberger K, Dutton JR, Hubel A. Front Bioeng Biotechnol. 8:1. doi: 10.3389/fbioe.2020.00001. Link

Cord blood research, banking, and transplantation: achievements, challenges, and perspectives. (2020) Mayani H, Wagner JE, Broxmeyer HE. Bone Marrow Transplant. 55(1):48-61. doi: 10.1038/s41409-019-0546-9. Link

 Bringing order to the matrix. (2020) Provenzano PP. Nat Mater. 19(2):130-131. doi: 10.1038/s41563-019-0592-0. Link

Mesenchymal stromal cells shape the MDS microenvironment by inducing suppressive monocytes that dampen NK cell function. (2020) Sarhan D, Wang J, Sunil Arvindam U, Hallstrom C, Verneris MR, Grzywacz B, Warlick E, Blazar BR, Miller JS. JCI Insight. 5(5). pii: 130155. doi: 10.1172/jci.insight.130155. Link

Chondroitin sulfate proteoglycan Windpipe modulates Hedgehog signaling in Drosophila. (2020) Takemura M, Noborn F, Nilsson J, Bowden N, Nakato E, Baker S, Su TY, Larson G, Nakato HMol Biol Cell. 31(8):813-824. doi: 10.1091/mbc.E19-06-0327. Link

Hearts and Hands: the good, the bad, and the ugly. (2020) van Berlo JH, Garry DJCardiovasc Res. 116(3):470-472. doi: 10.1093/cvr/cvz273. Link

Abcg2-expressing side population cells contribute to cardiomyocyte renewal through fusion. (2020) Yellamilli A, Ren Y, McElmurry RT, Lambert JP, Gross P, Mohsin S, Houser SR, Elrod JW, Tolar J, Garry DJ, van Berlo JH. FASEB J.  doi: 10.1096/fj.201902105R. Link

Pluripotent stem cell-derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor activity. (2020) Zhu H, Blum RH, Bjordahl R, Gaidarova S, Rogers P, Lee TT, Abujarour R, Bonello GB, Wu J, Tsai PF, Miller JS, Walcheck B, Valamehr B, Kaufman DS. Blood. 2135(6):399-410. doi: 10.1182/blood.2019000621. Link

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin alphavbeta5 Axis. (2020) Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN. Cell Stem Cell. 26(2):187-204.e10. doi: 10.1016/j.stem.2019.11.016. Link

Share this post

Related News