Stem Cell Scientists find new method to reduce symptoms of Duchenne Muscular Dystrophy in mice
January 27, 2020
To test their theory that by targeting the blood vessels in skeletal muscle that tissue could be repaired, researchers Atsushi Asakura and Mayank Verma worked with Shire Human Genetic Therapies to engineer antibodies to specifically target blood vessels.
In their study of mice using the antibodies, they found less damage, more stem cells, less scar tissue and the ability to produce more stable muscle fiber.
Eventually they hope to collaborate with Shire Human Genetic Therapies to possibly apply the technique to humans with Duchenne Muscular Dystrophy.