Dr. Shamar Young Awarded RSNA Research and Education Foundation Grant

Shamar Young, MD, assistant professor in the University of Minnesota Medical School’s Department of Radiology, received a Research and Education Foundation grant from the Radiological Society of North America (RSNA). Dr. Young’s application titled, “Immunomodulatory Effects of Radioembolization: A Prospective Study of Peripheral Monocyte Modulation, Immune Cell Infiltration, and Cytokine Variation,” was among the top-ranked by the Research & Education Board of Trustees.

The one-year grant will support Dr. Young’s research looking at the effects that radioembolization, a common treatment for primary and secondary malignant disease of the liver, has on the immune system. 

“The immune system has been clearly shown to be an important player in how cancer develops and in fighting off cancer, which has led to the rise of immuno-oncology,” Dr. Young said. “There’s a lot of feeling that radioembolization could be synergistic with those immuno-oncology agents in terms of providing improved outcomes for patients. What’s really important for us to do before we start running those trials, in my opinion, is to understand what radioembolization itself does to the immune system.” 

The study will analyze patients who are undergoing radioembolization for the treatment of primary liver tumors and evaluate how the immune system is affected.

Dr. Young will be collaborating both inside and outside the Department of Radiology with Jafar Golzarian, MD, professor in the Department of Radiology, and Emil Lou, MD, PhD, associate professor, and Evidio Domingo-Musibay, MD, assistant professor, both in the Department of Medicine’s Division of Hematology, Oncology and Transplantation.