COVID-19 Publications

University of Minnesota Medical School scientists have published research on a variety of topics related to COVID-19. Below is an ongoing list of these publications.

Scientific Understanding

Shang J, Ye G, Shi K, et al. Structural basis of receptor recognition by SARS-CoV-2. Nature. 2020;581(7807):221‐224. doi:10.1038/s41586-020-2179-y
Nature
Hideki Aihara-Biochemistry, Molecular Biology, and Biophysics
Fang Li- Veterinary and Biomedical Sciences

Yushun Wan, Jian Shang, Rachel Graham, Ralph S. Baric, Fang Li, Receptor Recognition by the Novel Coronavirus from Wuhan: An Analysis Based on Decade-Long Structural Studies of SARS Coronavirus Journal of Virology Mar 2020, 94 (7) e00127-20; DOI: 10.1128/JVI.00127-20
Journal of Virology
Fang Li- Veterinary and Biomedical Sciences

Cawthon, P.M., Orwoll, E.S., Ensrud, K.E., Cauley, J.E., Kritchevsky, S.B., Cummings, S.R., Newman, A., Assessing the Impact of the COVID-19 Pandemic and Accompanying Mitigation Efforts on Older Adults, The Journals of Gerontology: Series A, , glaa099,
The Journals of Gerontology, Series A- Biological Sciences and Medical Sciences
Kristin Ensrud- VA Affiliate

Stovitz, Steven D., Coronavirus (COVID-19) Assessments and the Importance of Calculating the Probability of Illness- Med Sci Educ. -Med Sci Educ. 2020 Apr 22 : 1–2. doi: 10.1007/s40670-020-00964-7 [Epub ahead of print] PMCID: PMC7176373 PMID: 32328341
Medical Science Educator
Steven Stovitz- Family Medicine and Community Health

Madjid M, Safavi-Naeini P., Solomon S.D., Vardeny O. Potential Effects of Coronaviruses on the Cardiovascular System: A Review. JAMA Cardiol. Published online March 27, 2020. doi:10.1001/jamacardio.2020.128
JAMA Cardiology (in press)
Orly Vardeny- VA Affiliate

Somma, A., Gialdi, G., Krueger, R., Markon, K., Frau, C., Lovallo, S., & Fossati, A. (2020). Dysfunctional personality features, non-scientifically supported causal beliefs, and emotional problems during the first month of the COVID-19 pandemic in Italy. Personality and Individual Differences, 165, 110139.
Robert Krueger- Psychology

McPherson, S., Keunen, J., Bird, A., Chew, E., & Van Kuijk, F. (2020). Investigate Oral Zinc as a Prophylactic Treatment for Those at Risk for COVID-19. American Journal of Ophthalmology. https://doi: 10.1016/j.ajo.2020.04.028
American Journal of Ophthalmology
Erik Van Kuijk- Ophthalmology

Sen, S., Karaca-Mandic, P., & Georgiou, A. (2020). Association of Stay-at-Home Orders With COVID-19 Hospitalizations in 4 States. JAMA : The Journal of the American Medical Association. Https://doi:10.1001/jama.2020.9176
Soumya Sen and Pinar Karaca-Mandic-- Carlson School of Management

Wackett, L. (2020). SARS‐CoV‐2: Environment and spread: An annotated selection of World Wide Web sites relevant to the topics in environmental microbiology. Environmental Microbiology, 22(6), 2443-2444.
Environmental Microbiology
Lawrence Wackett- Biochemistry, Molecular Biology, and Biophysics

Wang, Y., Liu, M., & Gao, J. (2020). Enhanced receptor binding of SARS-CoV-2 through networks of hydrogen-bonding and hydrophobic interactions. Proceedings of the National Academy of Sciences of the United States of America,117(25), 13967-13974.
PNAS
Jiali Gao- Chemistry

Clinical Care

Marini JJ, Gattinoni L. Management of COVID-19 Respiratory Distress. JAMA. Published online April 24, 2020. doi:10.1001/jama.2020.6825
JAMA
John Marini- Regions affiliate

Mayes, RC., Downar, J., Dichter, JR., et. al Triage Scarce critical care resources in COVID-19: an implementation guide for regional allocation An expert panel report of the Task Force for Mass Critical Care and the American College of Chest Physicians, Chest Journal, https://doi.org/10.1016/j.chest.2020.03.063
Chest Journal
Jeffery Dichter- Medicine

Michaels MG, La Hoz RM, DanzigerIsakov L, et al. Coronavirus disease 2019: Implications ofemerging infections for transplantation. Am J Transplant. 2020;00:1–5.
AMJ Transplant
Timothy Pruett-Surgery

Sultan S, Lim JK, Altayar O, et al. AGA Institute Rapid Recommendations for Gastrointestinal Procedures During the COVID-19 Pandemic [published online ahead of print, 2020 Mar 31]. Gastroenterology. 2020;. doi:10.1053/j.gastro.2020.03.072
Gastroenterology
Shahnaz Sultan- Minneapolis VA Healthcare System

Lakkireddy DR, Chung MK, Gopinathannair R, et al. Guidance for Cardiac Electrophysiology During the Coronavirus (COVID-19) Pandemic from the Heart Rhythm Society COVID-19 Task Force; Electrophysiology Section of the American College of Cardiology; and the Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, American Heart Association [published online ahead of print, 2020 Apr 1]. Heart Rhythm. 2020;. doi:10.1016/j.hrthm.2020.03.028
Heart Rhythm
Alejandra Guitierrez- Cardiology Disease Medical Fellow

Vaduganathan, M. Orly, V et al. Renin- Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19 N Engl J Med 2020; 382:1653-1659
DOI: 10.1056/NEJMsr2005760
NEJM
Orly Vardeny-VA Affiliate

Tignanelli, CJ; Ingraham, NE; Sparks; et al. Antihypertensive drugs and risk of COVID-19? CORRESPONDENCE| VOLUME 8, ISSUE 5, E30-E31, MAY 01, 2020 Published:March 26, 2020DOI:https://doi.org/10.1016/S2213-2600(20)30153-3
The Lancet Respiratory Medicine
Christopher Tignanelli- Surgery
Nicholas Ingraham- Medicine Fellow
Ronald Reilkoff- Medicine
Tamara Bezdicek- Pharmacy resident PGY1
Bradley Benson- Medicine
Timothy Schacker- Medicine
Jeffrey Chipman- Surgery
Michael Puskarich- Emergency Medicine

Ingraham, N.E., Boulware, D., Sparks, M.A. et al. Shining a light on the evidence for hydroxychloroquine in SARS-CoV-2. Crit Care 24, 182 (2020). https://doi-org.ezp2.lib.umn.edu/10.1186/s13054-020-02894-7
Critical Care
Kay Ingraham -VA Affiliate
Tim Schacker- Medicine
David Boulware-Medicine
Brad Benson-Medicine
Thomas Murray-Biostatistics Public Health
John Connett--Biostatistics Public Health
Jeffrey Chipman-Surgery
Christopher Tignanelli-Surgery

Pastick, K.A., Okafor, E.C., Wang, F., Lofgren, S.M., Skipper, C.P., Nicol, M.R., Pullen, M.F., Rajasingham, R., McDonald, E.G., Lee, T.C., Schwartz, I.S.,Kelly, L.E., Lother, S.A., Mitjà, O., Letang, E., Abassi, M., Boulware, D.R., Review: Hydroxychloroquine and Chloroquine for Treatment of SARS-CoV-2 (COVID-19), Open Forum Infectious Diseases, Volume 7, Issue 4, April 2020, ofaa130, https://doi-org.ezp1.lib.umn.edu/10.1093/ofid/ofaa130
Open Forum for Infectious Disease
Katelyn Pastick - Med Student- MS4
Elizabeth Okafor- Med Student MS4
Sarah Lofgren- Medicine
Caleb Skipper- Medicine Fellow
Melanie Nicol-Pharmacy
Matthew Pullen--Global Health Fellow
Radha Rajasingham- Medicine
Mahsa Abassi-Medicine
David Boulware- Medicine

Dewey, C., Hingle, S., Goelz, E., Linzer, M., Supporting Clinicians During the COVID-19 Pandemic, Annals of Internal Medicine 2020 172:11, 752-753 https://doi.org/10.7326/M20-1033
Annals of Internal Medicine
Mark Linzer- Hennepin Healthcare Affiliate
Elizabeth Goelz- Hennepin Healthcare Affiliate

Lother S.A., Abassi M., Agostinis A., et al. Post-exposure prophylaxis or pre-emptive therapy for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): study protocol for a pragmatic randomized-controlled trial [published online ahead of print, 2020 May 7]. Can Journal Anaesth. 2020; 1‐11. doi:10.1007/s12630-020-01684-7
Canadian Journal of Anesthesiology
David Boulware-Medicine
Mahsa Abassi- Medicine
Elizabeth Okafor- Medical Student MS3
Radha Rajasingham- Medicine

Ingraham, N., Lotfi-Emran, S., Thielen, B., Techar, K., Morris, R., Holtan, S., . . . Tignanelli, C. (2020). Immunomodulation in COVID-19. The Lancet: Respiratory Medicine.
The Lancet Respiratory Medicine
Nicholas Ingraham -Medicine Fellow
Sahar Lotfi-Emran - Medicine Fellow
Beth Thielen - Medicine Fellow
Kristina Techar- Affiliate- Hennepin Healthcare
Shernan Holtan- Medicine
Adams Dudley- Medicine
Christopher Tignanelli-Surgery

Al-Kofahi, M., Jacobson, P., Boulware, D., Matas, A., Kandaswamy, R., Jaber, M., . . . Nicol, M. (2020). Finding the dose for hydroxychloroquine prophylaxis for COVID-19; the desperate search for effectiveness. Clinical Pharmacology and Therapeutics, Clinical pharmacology and therapeutics,.
Clinical Pharmacology and Therapeutics
Mahmoud Al-Kofahi- Pharmacology
Pamala Jacobson-Pharmacology
David Boulware-Medicine
Arthur Matas- Surgery
Raja Kandaswamy- Surgery
Mutaz Jaber- Pharmacology
Radha Rajasingham- Medicine
Jo-Anne Young- Medicine
Melanie Nico- Pharmacology

Ingraham, N., Barakat, A., Reilkoff, R., Bezdicek, T., Schacker, T., Chipman, J., . . . Puskarich, M. (2020). Understanding the Renin-Angiotensin-Aldosterone-SARS-CoV-Axis: A Comprehensive Review. The European Respiratory Journal, The European respiratory journal, 27 April 2020.
European Respiratory Journal
Nicholas Ingraham -Medicine Fellow
Abdo Barakat - Hennepin Healthcare Affiliate
Ronald Reilkoff- Medicine
Timothy Schacker - Medicine
Jeffrey Chipman -Surgery
Christopher Tignanelli-Surgery
Michael Puskarich- Emergency Medicine

Bhirmraj, A., Morgan, R., Shumaker, A. , Lavergne, V., Baden, L., Chii-Chung Cheng, V., Edwards, K., Gandhi, R., Muller, W., O'Horo, J., Shoham, S., Murad, H., Mustafa, R., Sultan, S., Falck-Ytter, Y. (2020). Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19, Infectious Disease Society of America.
Infectious Disease Society of America
Shahnaz Sultan- Medicine

Prekker M.E., Brunsvold M.E., Bohman J.K., et al. Regional Planning for Extracorporeal Membrane Oxygenation Allocation During Coronavirus Disease 2019 [published online ahead of print, 2020 Apr 25]. Chest. 2020;S0012-3692(20)30769-8. doi:10.1016/j.chest.2020.04.026
Chest
Melissa Brunsvold- Surgery
Gwenyth Fischer-Pediatrics

Journal of Pharmacokinetics and Pharmacodynamics
Mahmoud Al-Kofahi - Pharmacy

Clemente, V., D’Arcy, P., & Bazzaro, M. (2020). Deubiquitinating Enzymes in Coronaviruses and Possible Therapeutic Opportunities for COVID-19. International Journal of Molecular Sciences., 21(10), 3492.
International Journal of Molecular Sciences
Martina Bazzaro- OBGYN

Lou, E., & Subramanian, S. (2020). Changing Oncology Treatment Paradigms in the COVID-19 Pandemic. Clinical Colorectal Cancer, 2020.
Clinical Colorectal Cancer
Emil Lou - Medicine
Subbaya Subramanian -Surgery

Debes, J., Anugwom, C., & Aby, E. (2020). Systematic analysis of acute liver injury during SARS-CoV-2 infection. Digestive and Liver Disease, Digestive and Liver. doi.org/10.1016/j.dld.2020.05.006
Digestive and Liver Diseases
Jose Debes- Medicine

Ghannam, M., Alshaer, Q., Al-Chalabi, M., Zakarna, L., Robertson, J., & Manousakis, G. (2020). Neurological involvement of coronavirus disease 2019: A systematic review. Journal of Neurology, 1-19. doi: 10.1007/s00415-020-09990-2
Journal of Neurology
Georgios Manousakis and Jetter Robertson- Neurology

Umakanthan, S., Sahu, P., Ranade, A., Bukelo, M., Rao, J., Abrahao-Machado, L., Shal, S., Kumar, H., & KV, D. (2020). Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19). Postgraduate Medical Journal, 0, 1-6. doi: 10.1136/postgradmedj-2020-138234
Postgraduate Medical Journal
Joseph Rao-Surgery Post Doctoral Associate