We create and deploy genetically modified cells while educating the next generation of genetic engineers.

The Center for Genome Engineering (CGE) faculty advances the research and clinical objectives of the UMN’s medical enterprise, including our understanding of biological processes and ways to successfully modify living cells for many applications.


Center for Transposon Research | Dr. Steve Ekker
Center for Genome Engineering | Dr. Dan Voytas
New Leadership | Dr. David Largaespada
Co-Director Dr. Branden Moriarity
Center for Genome Engineering Research

The ability to modify DNA in living cells is revolutionizing the life sciences. 
Contributions have ranged from construction of the first, functional vertebrate transposon (Sleeping Beauty) – which has proven effective for DNA delivery and mutagenesis – to the invention of Transcription Activator-like Effector Nucleases (TALENs). CGE technology advances functional genomics, provides therapeutic strategies to correct mutations underlying genetic disease, and has resulted in new crop varieties that are already in the field.

Center for Genome Engineering Collaboration

Cooperative academic institutions developing regenerative therapeutics for mutations in underlying genetic diseases
CGE promotes the shared research and educational objectives of its faculty by:

  • providing administrative support
  • maintaining service contracts for key pieces of equipment
  • bringing in external seminar speakers
  • providing financial support to students and postdocs