Optical imaging via multi-photon microscopy can measure activity-dependent changes in fluorescent signals directly from individual neurons, astrocytes and blood vessels in the living brain.
We expect strong synergy between the Optical Imaging MDT and the MRI researchers. For this reason, all the optical MDT hires will have their laboratories housed within the CMRR. To date, two researchers with optical imaging expertise have been hired and two additional candidates are currently in the process of being interviewed. Generating activity patterns from large ensembles of cells will generate large volumes of complex data. The optical imaging MDT committee therefore plans to recruit additional faculty with expertise in computational strategies such as machine learning, deep neural networks, graph theory and multi-scale approaches for the analysis of big data.