MIBAM Mouse CORE

Directed by Drs. Laura Niedernhofer and Christina Camell, the goal of the MIBAM Mouse Core is to provide researchers with mouse models of natural and accelerated aging to examine the roles of  the pillars of aging including DNA damage, senescence, inflammation and mitochondrial dysfunction in driving aging and age-related diseases as well as testing therapeutics to extend health span. The Core has a large and complex animal colony that functions to provide a unique resource for researchers studying pillars of aging systemically and within individual organs. These mouse models include accelerated aging models, transgenic and naturally aged models. The Mouse Core regularly works with researchers to provide tissue samples, collect in vivo data and perform therapeutic studies. 

• Experiment design assistance, guidance and execution.
• Animal husbandry (breeding/weaning/diet/health monitoring/aging) of experimental and aged mice by request.
• Drug/Compound Dosing.
• Special Diet/Restrictions.
• Phenotyping (BW/Metabolic/Health Eval/Live Sample Collection).
• Necropsy – Basic/Advanced (Tissue Collection).
• Tissue Bank Access.
• Historical Data Available by Request.

• Available Strains (Public) – TBD
• Aged WT Mice (F1 and/or C57Bl6) per request and availability, Standard Colony
• Specific Animal Strain Requests – Ordered from collaborators/Jackson Labs/Charles River