$1.8M NIH Grant Will Seek to Understand Circadian Sleep Problems in Neurological Diseases
Author: | October 20, 2020
Dr. Ruifeng (Ray) Cao is featured in this article written by Alyssa Dindorf, Communications Specialist, outlining his current research funded by a grant from the National Institute of Health. The grant from the National Institute of Neurological Disorders and Stroke (NINDS), totaling $1.8 million over five years, will focus on collecting new knowledge critical to understanding the role of mTOR activities in the brain clock that are associated with abnormal behavioral conditions.
“People with neurodegenerative disorders, such as Alzheimer’s disease, often have disrupted sleep and wake cycles,” Dr. Cao said. “These disruptions often occur much earlier in people whose memories are intact but show some evidence of Alzheimer’s in their brain scans. Patients often experience frequent awakenings at night and wake fragmentation during the day, as patients spend much of the daytime napping.”