Led by Associate Professor, Dr. Lynne Bemis, the current focus of the Bemis laboratory is the identification and characterization of noncoding RNAs in liquid biopsies. Extracellular RNAs (exRNAs) are an abundant group of noncoding RNAs, dominated by the microRNAs, tRNAs, and tRNA fragments. These exRNAs are potential biomarkers in a wide range of health conditions including cancer, infectious disease and alcoholism.
Molecular Methods Currently Being Developed
Dr. Bemis specializes in teaching precision medicine, molecular genetics, health disparities, cancer biology, and basic science concepts. Dr. Bemis is also the Course Director for Medical Student Journal Club and teaching faculty in the GENA curriculum.
Bemis Group Recent Publications
- Zhou K, Diebel KW, Holy J, Skildum A, Odean E, Hicks DA, Schotl B, Abrahante JE, Spillman MA and Bemis LT. A tRNA Fragment, tRF5-Glu, Regulates BCAR3 Expression and Proliferation in Ovarian Cancer Cells. Oncotarget. 2017; in press
- Zhou K, Spillman MA, Behbakht K, Komatsua JM, Abrahante JE, Hicks DA, Schotl B, Odean E, Jones KL, Graner MW, Bemis LT. A Method for Extracting and Characterizing RNA from Urine: for downstream PCR and RNAseq Analysis. Analytical Biochemistry. 2017; in press.
Bemis Group News
2017-October – Kun Zhou starts his Postdoctoral Fellowship at the Zetter Laboratory, Children’s Hospital Boston, MA
2017-September- Kun Zhou presents: tRNA Fragment at Lab-Bench talks
2017- August – Cortney Herseth presents a poster at the Bridges and Pathways Event, Discovering Variants of tRF5-Glu
2017- July -Aaron Clarke comes back for a couple months of research before heading off to graduate school at Santa Cruz.
2017 – June – Lynne Bemis chaired session at Liquid Biopsy Conference, New Tools: Advancing Detection for Liquid Biopsy, San Francisco, CA
2017 – May – Lynne Bemis presents with GENA in Bethel, Alaska
2017 – April – Lynne Bemis presents: Lyme Disease Research at the University of Minnesota, for the Garden Club of Superior Wisconsin.
2017 – March – Lynne Bemis presents with GENA, Flathead Lake, Montana
2017 – February- Lynne Bemis presents: Lyme Disease Research at UMN for the Superior Rotary Club
2016 – November – Kun Zhou presents: A tRNA Fragment regulates BCAR3 expression in Ovarian Cancer Cells. (Chosen for Oral Presentation) 7th Annual Masonic Cancer Center Research Symposium, Minneapolis, MN
2016 – October - Aaron B. Clarke presents: tRNA Fragments as Biomarker for Ovarian Cancer. Society for the Advancement of Chicanos and Native Americans in Science (SACNAS) annual meeting,
2016 – October - Kun Zhou presents: Regulatory Mechanisms of tRNA Fragments in Ovarian Cancer Cells. Rustbelt RNA meeting
2016 – June – Kun Zhou presents: Detection and Regulation of BCAR3 in Ovarian Cancer Cells. Cancer Moonshot Summit University of Minnesota Medical School Duluth Campus
2016 – June – Aaron B. Clarke presents: New Model System for the Study of Ovarian Cancer. Cancer Moonshot Summit at University of Minnesota Medical School Duluth Campus