Yang Lab

Synapses are the fundamental units of neural communication in the brain. Using multidisciplinary approaches, we study how synaptic structure and function are precisely shaped during development and how their dysfunctions lead to neurological disorders. By understanding the physio-pathological roles of critical synaptic proteins and ion channels at the cellular, circuitry and system levels, we aim to identify novel targets and further develop pharmacological and genetic therapies for neurodevelopment disorders, such as autism spectrum disorder.

Research Techniques
  • Multi-electrode patch-clamp
  • Confocal and two-photon imaging
  • In vivo Ca2+ Imaging
  • Chemogenetics
  • Optogenetics
  • Viral gene transfer
  • Viral neuronal tracing
  • Biochemistry and immunocytochemistry
  • Molecular biology
  • Mouse behavioral analysis
  • Transgenic mouse models
Yi-Mei (Amy) Yang, PhD
Associate Professor, Principal Investigator

Yuan Hsin (Owen) Chao, PhD
Assistant Professor

Salil Saurav Pathak, PhD
Researcher 5
Maya Shebala
MS Candidate
Amara Wilcox
Undergraduate Student

Former Lab Members
Nathan Dunaway
Undergraduate Student
Sam Himes
Undergraduate student
Swati Maitra, PhD
Postdoctoral Associate
Dymond Record
Undergraduate Student
Kiersten Strate
Undergraduate student
Houa Thao
Undergraduate Student
Richelle Yunger
Undergraduate student
Hao Zhang
Graduate Student

Name: Yi-Mei (Amy) Yang, PhD
Title: Principal Investigator
Email: ymyang@d.umn.edu
Phone: (218) 726-7818
Office Address: 
Department of Biomedical Sciences
337 SMed
1035 University Drive
Duluth, MN 55812

Yi-Mei (Amy) Yang, PhD