Clinical Quality, Outcomes, Discovery, and Evaluation Core (CQODE)
Democratizing healthcare data access
We support researchers to improve healthcare quality and delivery through data-centric research
About CQODE
Democratizing data access for clinical researchers to improve healthcare quality and delivery.
We create pathways for data-centric research that enhances healthcare quality and delivery. By democratizing healthcare data access we empower clinical and non-clinical researchers to share resources, achieve economies of scale and accelerate new projects that drive faster evaluation, insights and discovery.
CQODE’s Services
CQODE’s focus is to provide data infrastructure and streamlined access to support the growing field of health services research. This includes outcomes research, clinical quality improvement, and implementation science with a focus on providing the following services:
- Our comprehensive data repository helps researchers analyze population-level outcomes to generate real health benefits for society.
- We deliver timely and targeted data to ensure the right care reaches the right patient at the right time.
- We assist with study design and initiation, as well as grant and manuscript writing and submission.
Work with us! Go to our Center's services page and fill out the CLHSS request form to get started.
Healthcare Data Access
Looking for data to support your research? CQODE provides access to an extensive library of data sources tailored to meet the specific goals of your project. Here are some examples of the data servers we work with:
- University of Minnesota Electronic Health Records (UMN EHR) (e.g., Acute DataMart)
- State Inpatient Database (HCUP SID) (Healthcare Cost and Utilization Project)
- National Inpatient Database (HCUP NIS) (Healthcare Cost and Utilization Project)
- National Trauma Data Bank (NTDB)
- National Surgical Quality Improvement Program (NSQIP)
- Trauma Quality Improvement Program (TQIP)
- Surveillance, Epidemiology, and End Results (SEER)
- National Cancer Database (NCDB)
CQODE Research Projects
Pediatric Surgery Outcomes
Investigator
Randi Lassiter, MD
- Department of Surgery
The Project
The CQODE team collaborated with M Health Fairview to develop two new variables for a cohorting project. This project compared outcomes of neonatal patients who had surgical interventions with those who did not. The team ensured fast data delivery and maintained regular communication for project scope and management, flow diagram creation, and data approval.
Status: past
Rural vs Urban Colorectal Patients
Investigator
Jeffrey Chipman, MD
- Department of Surgery
The Project
This study aimed to evaluate differences in outcomes among patients with colon diseases treated in rural versus urban hospitals. The CQODE team supported the project by developing a cohesive analysis plan, refining it through multiple iterations to effectively communicate the story behind the data.
Status: in progress
Impact of Treatment on Pancreatic Cancer Survival
Investigator
Ajay Prakash, MD, PhD
- Department of Medicine
The Project
Researchers used real-world data to evaluate how initial treatment modalities influenced survival outcomes for patients with stage I-III pancreatic adenocarcinoma within the M Health Fairview medical system.
Status: past
University of Minnesota awarded $21M to lead research revealing effects of vagus nerve stimulation in humans
The Project
The Research Evaluating Vagal Excitation and Anatomical Links (REVEAL) project, a $21 million NIH-funded initiative, will study the anatomical connections and functional effects of vagus nerve stimulation, an FDA-approved treatment for epilepsy and depression, over three years.
Led by the University of Minnesota, the multidisciplinary team team includes faculty from the Medical School, College of Science and Engineering, and School of Public Health, representing key centers like CQODE, the Center for Neuroengineering, the Institute for Engineering in Medicine, and the Minnesota Consortium for Autonomic Neuromodulation.
Publications
Effectiveness of a Breast Cancer Educational Conference Targeting Healthcare Workers in Honduras
Prathibha S, Zuniga M, Bejarano S, Duarte F, Antunez M, Molina AZ, Hoven N, Marmor S, Witt J, Hui J, Tuttle TM
Risk-Specific Training Cohorts to Address Class Imbalance in Surgical Risk Prediction
Balch JA, Ruppert MM, Guan Z, Buchanan TR, Abbott KL, Shickel B, Bihorac A, Liang M, Upchurch GR Jr, Tignanelli CJ, Loftus TJ
Unveiling Hidden Biases in Pain Management for Nephrolithiasis
Frye HH, Ganesan V, Agarwal D, Patterson B, Herman A, Borofsky MS
Risk of Post-Intubation Laryngotracheal Stenosis With Respect to COVID-19 Status in a Large Multicenter Cohort Cross-Sectional Study
Gray R, Pradhan PM, Hoffmeister J, Misono S, Cho R, Tignanelli C
American Association for the Surgery of Trauma/American College of Surgeons Committee on Trauma clinical protocol for postdischarge venous thromboembolism prophylaxis after trauma
Berndtson AE, Cross A, Yorkgitis BK, Kennedy R, Kochuba MP, Tignanelli C, Tominaga GT, Jacobs DG, Ashley DW, Ley EJ, Napolitano L, Costantini TW
Association of Symptomatic Dizziness With All-Cause and Cause-Specific Mortality
Lin ME, Gallagher TJ, Straughan A, Marmor S, Adams ME, Choi JS
Acute Appendicitis Treatment Strategies and Mortality Based on Critical Illness on Admission: An Observational Study
King S, Proper J, Siegel LK, Ingraham NE, Tignanelli CJ, Chipman JG, Ho J
Omission of axillary lymph node dissection for breast cancer patients with three or more positive sentinel lymph nodes
Prathibha S, White M, Kolbow M, Hui JYC, Brauer D, Ankeny J, Jensen EH, LaRocca CJ, Marmor S, Tuttle TM
Predictors of Functional Decline Among Critically Ill Surgical Patients: A National Analysis
An SJ, Smith C, Davis D, Gallaher J, Tignanelli CJ, Charles A
Management and staging of anal adenocarcinoma in the United States: a population-based analysis
Troester A, Kohn J, Wang Q, Weaver L, Hassan I, Gaertner W, Marmor S, Goffredo P
Developing A Baseline Metabolomic Signature Associated with COVID-19 Severity: Insights from Prospective Trials Encompassing 13 U.S. Centers
Yang K, Kang Z, Guan W, Lotfi-Emran S, Mayer Z, Guerrero C, Steffen B, Puskarich M, Tignanelli C, Lusczek E, Safo S
Beating the odds: long-term survival after lung transplantation
Salami A, Huddleston S
The prognostic significance of laterality in endoscopically resected colonic adenomas with high-grade dysplasia
Boatman S, Kohn J, Mott S, Marmor S, Madoff R, Gaertner W, Shaukat A, Melton G, Hassan I, Goffredo P
Validation of a Proprietary Deterioration Index Model and Performance in Hospitalized Adults
Byrd T, Southwell B, Ravishankar A, Tran T, Kc A, Phelan T, Melton-Meaux G, Usher M, Scheppmann D, Switzer S, Simon G, Tignanelli C
Outpatient treatment of COVID-19 and incidence of post-COVID-19 condition over 10 months (COVID-OUT): A multicentre, randomised, quadruple-blind, parallel-group, phase 3 trial
Bramante C, Buse J, Liebovitz D, Nicklas J, Puskarich M, Cohen K, Belani H, Anderson B, Huling J, Tignanelli C, Thompson J, Pullen M, Lemus Wirtz E, Siegel L, Proper J, Odde D, Klatt N, Sherwood N, Lindberg S, Karger A, Beckman K, Erickson S, Fenno S, Hartman K, Rose M, Mehta T, Patel B, Griffiths G, Bhat N, Murray T, Boulware D, COVID-OUT Study Team
More than the sum of its parts? The emerging role of multidevice neuromodulation in epilepsy treatment
Sabal L, McGovern R
68 Metformin prevents the diagnosis of Long Covid in phase 3 trial of early treatment
Bramante C, Wirtz E, Buse J, Boulware D, Nicklas J, Odde D, Cohen K, Puskarich M, Tignanelli C, Klatt N, Leibovitz D, Belani H
Predictors of discharge disposition and mortality following hospitalization with SARS-CoV-2 infection
Ikramuddin F, Melnik T, Ingraham N, Nguyen N, Siegel L, Usher M, Tignanelli C, Morse L
A novel, evidence-based, comprehensive clinical decision support system improves outcomes for patients with traumatic rib fractures
Jones E, Ninkovic I, Bahr M, Dodge S, Doering M, Martin D, Ottosen J, Allen T, Melton GB, Tignanelli CJ
Proteomic pathways associated with developing severe disease for patients with COVID-19: A biologic analysis of data from two multicenter randomized controlled trials encompassing 13 U.S. hospitals
Samorodnitsky S, Castro-Pearson S, Yang K, Lotfi-Emran S, Ingraham NE, Bramante C, Geising S, Jones EK, Wacker D, Puskarich M, Lusczek E, Safo S, Tignanelli CJ
Nationwide utilization of computerized dynamic posturography in an era of deimplementation
Chieffe D, Zuniga SA, Marmor S, Adams ME
Association of Visit Volume and Sociodemographic Characteristics With Vocal Improvement Among Older US Adults With a Self-reported Voice Problem
Marmor S, Cohen SM, Misono S
Impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and booster on coronavirus disease 2019 (COVID-19) symptom severity over time in the covid-out trial
Boulware D, Murray T, Proper J, Tignanelli C, Buse J, Liebovitz D, Nicklas J, Cohen K, Puskarich M, Belani H, Siegel L, Klatt N, Odde D, Karger A, Ingraham N, Hartman K, Rao V, Hagen A, Patel B, Fenno S, Avula N, Reddy N, Erickson S, Lindberg S, Fricton R, Lee S, Zaman A, Saveraid H, Tordsen W, Pullen M, Sherwood N, Huling J, Bramante C, COVID-OUT study team
Use of endocrine therapy for estrogen receptor-positive breast cancer among American Indians and Alaska natives
Engelking M, Marmor S, Burjak M, Hinojos M, Lloyd W, Switalla KM, Tuttle TM
Clinical Benefit of Vagus Nerve Stimulation for Epilepsy: Assessment of Randomized Controlled Trials and Prospective Non-Randomized Studies
Cramer S, McGovern R, Chen C, Park, M
Real-world impact of initial treatment modality on survival outcomes in patients with stage I-III pancreatic ductal adenocarcinoma
Prakash A, Schwanke J, Le-Kumar T, Patterson B, Marmor S, Tignanelli C, Jensen EH, Lou E
Invited commentary: Postoperative artificial intelligence model for ICU triage
Byrd T, Ho J, Tignanelli C
CQODE People
Leadership
- Scientific Co-Director, Nick Ingraham, MD, MS
- Scientific Co-Director, Schelomo Marmor, PhD, MPH
- Scientific Co-Director, Chris Tignanelli, MD, MS
- Steering Committee, Stephen Huddleston, MD, PhD
- Steering Committee, Robert McGovern, MD
- Steering Committee, Stephanie Misono, MD, MPH, FACS
- Steering Committee, Billy Sveen, MD, MA
- Steering Committee, Rachel I. Vogel, PhD
Staff
- Data Science Manager, Akshay Bhardwaj, MS
- Data Analyst, Brooke Patterson, MPH
CQODE News
Request CQODE services through the CLHSS services request form
Contact CQODE directly for questions about a project or service request:
[email protected]