Research

micro research

Research is a primary mission of the Department of Microbiology and Immunology. Through externally and internally funded leading-edge research initiatives and collaborative partnerships, our faculty, students and research staff are expanding our understanding of microorganisms, disease, and the immune response. Microbiology and immunology provide the building blocks for the treatment of infections and other diseases.

2019 RESEARCH STATISTICS

  • 45 PEER-REVIEWED PUBLICATIONS
  • 24 NIH-FUNDED PROJECTS
  • $9.2M TOTAL EXTERNAL FUNDING
  • 1 HHMI FACULTY SCHOLAR

Recent Publications

Zafar, H., S. Altamirano, E.R. Ballou, and K. Nielsen. A titanic drug resistance threat in Cryptococcus neoformans. Curr. Opin. Microbiol. 52: 158-164; 2019.

Lamont, E.A., and A.D. Baughn. Impact of the host environment on the antitubercular action of pyrazinamide. EBioMedicine 49: 374-380; 2019.

Cameron, E.A., V. Sperandio, and G.M. Dunny. Enterococcus faecalis enhances expression and activity of the enterohemorrhagic Escherichia coli typeIII secretion system. mBio 10:e2547-19. 2019.

Fiege, J.K., I.A. Stone, R.E. Dumm, B.M. Waring, B.T. Fife, J. Agudo, B. Brown, N.S. Heaton, and R.A. Langlois. Long-term surviving influenza infected cells evade CD8+ T cell mediated clearance. PLoS Pathogens. doi.org/10.1371/journal.ppat.1008077. 2019.

Nelson, C.E., E.A. Thompson,, C.F. Quarnstrom, K.A. Fraser,, D.M. Seelig, S. Bhela, B.J. Burbach,, D. Masopust, and V. Vezys. Robust iterative stimulation with self-antigens overcomes CD8 T cell tolerance to self- and tumor antigens. Cell Reports. 28:3092-3104; 2019.

Willett, J.L.E., M.M. Ji, andG.M. Dunny. Exploiting biofilm phenotypes for functional characterization of hypothetical genes in Enterococcus faecalis. NPJ Biofilms and Microbiomes 5: 23. doi.org.10.1038/s41522-019-0099-0. 2019.

Burrack, A.L., E.J. Spartz, J.F. Raynor, I. Wang, M. Olson, and I.M. Stromnes. Combination PD-1 and PD-L1 blockade promotes durable neoantigen-specific T cell-mediated immunity in pancreatic ductal adenocarcinoma. Cell Reports 28: 2140-2155; 2019.

Cameron, L.C., B.M. Bonis, C.Q. Phan, L. Kent, A.K. Lee, and R.C. Hunter. A putative enoyl coA hydratase contributes to biofilm formation and antibiotic tolerance in Achromobacter xylosoxidans. NPJ Biofilms and Microbiomes. 5:20; 2019.

Fiege J.K., I.A. Stone, E.J. Fay, M.W. Markman, S. Wijeyesinghe, M.G. Macchietto, S. Shen, D. Masopust, and R.A. Langlois. The impact of TCR signal strength on resident memory T cell formation during influenza virus infection. J. Immunol. 203:936-945; 2019.

Research Ethics at the University of Minnesota

We are committed to protecting research participants, upholding ethical standards, and improving our practice at every step of our work.

Commitment to Research Ethics