The Atwood laboratory is focused on understanding the functions of specific connections, known as synapses, between brain cells and how these functions are impacted by exposure to addictive drugs like opioids, and alcohol. Synapses are the principal sites of information transfer between cells. Synaptic transmission determines animal behavior and is highly changeable. The process of synapses changing is called synaptic plasticity. This synaptic plasticity allows for a person or an animal’s learning and adaptation to their environment. However, many disease states can alter synaptic plasticity, which can negatively influence both learning and behavior. The Atwood laboratory uses a multidisciplinary approach, from molecular analyses to studies of animal behavior, to elucidate the function of specific synapses in brain circuits that influence behaviors that control consumption of addictive drugs. They are most interested in how binge alcohol drinking affects the brain and how prenatal opioid exposure impacts neurobehavioral development and function.
