Drs. Navare, Prielipp and Weinkauf Publish Case Report on Effectiveness of New Drug in Reversing Paralysis in Dialysis Patients

Sagar Navare, MD, Richard Prielipp, MD, and Julia Weinkauf, MD, University of Minnesota Medical School Department of Anesthesiology co-authored “Sugammadex Reversal of a Large Subcutaneous Depot of Rocuronium in a Dialysis Patient: A Case Report” in A & A Practice.

This case study follows a dialysis-dependent patient with end-stage renal disease to determine if Sugammadex, a new drug used to reverse anesthetic paralysis, is effective in this patient population.

“When people don’t have their neuromuscular relaxation adequately reversed after surgery, bad things can happen,” said Dr. Navare, “They can get pneumonia; they can be weak and fall; it can take longer for them to recover. This new agent is remarkable because it directly binds to the drug used as a muscle relaxant and immediately reverses its effects.”

The report was promising towards showing Sugammadex is a safe and reliable drug for patients with end-stage renal disease.

”It’s through papers like this that we can broaden the use of these drugs in a safe and reliable manner and in effect increase the safety of patients when they undergo general anesthesia needing neuromuscular blockade,” said Dr. Navare.

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