Recent Publications

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May 2024

Hooks G, Lu H, Eaton A, Trikudanathan G, Downs E, Freeman ML, Schwarzenberg SJ, Pruett TL, Chinnakotla S, Ramanathan K, Gregory Beilman, Bellin MD. Addressing long-term mortality risk in patients undergoing total pancreatectomy with islet autotransplant (TPIAT): causes of death and risk factors. HPB. 2024 May.

Haselhuhn JJ, Soriano PBO, Grover P, Dreischarf M, Odland K, Hendrickson NR, Jones KE, Martin CT, Sembrano JN, David Polly Jr. Spine surgeon versus AI algorithm full-length radiographic measurements: a validation study of complex adult spinal deformity patients. Spine Deformity. 2024 May.

Velazquez EP, Bradley Miller, Yuen KCJ. Somatrogon injection for the treatment of pediatric growth hormone deficiency with comparison to other LAGH products. Expert Review of Endocrinology & Metabolism. 2024 May.

Hambright WS, Duke VR, Goff AD, Goff AW, Minas LT, Kloser H, Gao X, Huard C, Guo P, Lu A, Mitchell J, Mullen M, Su C, Tchkonia T, Espindola Netto JM, Paul Robbins, Laura Niedernhofer, Kirkland JL, Bahney CS, Philippon M, Huard J. Clinical validation of C12FDG as a marker associated with senescence and osteoarthritic phenotypes. Aging Cell. 2024 May.

Vetter TA, Parthiban P, Stevens JA, Revelo XS, Kohr MJ, DeWayne Townsend. Reduced cardiac antioxidant defenses mediate increased susceptibility to workload-induced myocardial injury in males with genetic cardiomyopathy. Journal of Molecular and Cellular Cardiology. 2024 May.

Booker R, Wong M, Bancks MP, Carnethon MR, Lisa Chow, Lewis CE, Schreiner PJ, Alexandria SJ. The longitudinal association of adipose-to-lean ratio with incident cardiometabolic morbidity: The CARDIA study. Journal of Diabetes and its Complications. 2024 May.

Varady KA, Runchey MC, Reutrakul S, Vidmar AP, Lisa ChowClinical potential of fasting in type 1 diabetes. Trends in Endocrinology and Metabolism. 2024 May.

Downs EM, Hodges JS, Trikudanathan G, Freeman ML, Chinnakotla S, Kirchner V, Pruett TL, Gregory Beilman, Schwarzenberg SJ, Bellin MD. Essential Fatty Acid Deficiency is Common after Total Pancreatectomy and Islet AutoTransplantation. Pancreas. 2024 May 1.

Nelson AB, Lisa Chow, Dengel DR, Pan M, Hughey CC, Han X, Puchalska P, Crawford PA. Gender-based heterogeneity of FAHFAs in trained runners. PloS One. 2024 May 6.

Haselhuhn JJ, Kress DJ, Whyte MM, Soriano PBO, David Polly Jr. The Sacroiliac Joint Fusion Patient Population and Its Prevalence of Total Hip Arthroplasty. The Journal of the American Academy of Orthopaedic Surgeons. 2024 May 7.

Powers SK, Radak Z, Li Li Ji, Jackson M. Reactive oxygen species promote endurance exercise-induced adaptations in skeletal muscles. Journal of Sport and Health Science. 2024 May 7.

Stone W, Strege C, Miller W, Geurts AM, Grzybowski M, Riddle M, Lees C, Eide C, Keene DR, Tufa SF, Seelig D, McGrath J, Jakub Tolar. Creation and characterization of novel rat model for recessive dystrophic epidermolysis bullosa: Frameshift mutation of the Col7a1 gene leads to severe blistered phenotype. PLoS One. 2024 May 9.

Wang C, Gu C, Popp C, Vashisth P, Mustfa SA, Martella DA, Spiteri C, McLennan S, Sun N, Riddle M, Eide CR, Parsons M, Jakub Tolar, McGrath JA, Chiappini C. Integrating Porous Silicon Nanoneedles within Medical Devices for Nucleic Acid Nanoinjection. ACS Nano. 2024 May 10.

Liu SS, White JM, Chao Z, Li R, Wen S, Garza A, Tang W, Ma X, Chen P, Daniel S, Frank Bates, Yeo J, Calabrese MA, Yang R. A pseudo-surfactant chemical permeation enhancer to treat otitis media via sustained transtympanic delivery of antibiotics. Advanced Healthcare Materials. 2024 May 13.

Rasmussen DM, Semonis MM, Greene JT, Muretta JM, Thompson AR, Toledo Ramos S, Thomas DD, Pomerantz WCK, Freedman TS, Levinson NM. Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife. 2024 May 14

Miller JS, Rhein J, Davis ZB, Cooley S, McKenna D, Anderson J, Escandón K, Wieking G, Reichel J, Thorkelson A, Jorstad S, Safrit JT, Soon-Shiong P, Gregory Beilman, Chipman JG, Schacker TW. Safety and Virologic Impact of Haploidentical NK Cells Plus Interleukin 2 or N-803 in HIV Infection. The Journal of Infectious Diseases. 2024 May 15.

Nguyen T, Nakada Y, Wu Y, Zhao J, Daniel Garry, Sadek H, Zhang J. Cell-Cycle-Specific Autoencoding Improves Cluster Analysis of Cycling Cardiomyocytes. Stem Cells. 2024 May 15.Steinbeck BJ, Gao XD, McElroy AN, Pandey S, Doman JL, Riddle MJ, Xia L, Chen W, Eide CR, Lengert AH, Han SW, Blazar BR, Wandall HH, Dabelsteen S, Liu DR, Jakub Tolar, Osborn MJ. Twin prime editing mediated exon skipping/reinsertion for restored collagen VII expression in recessive dystrophic epidermolysis bullosa. The Journal of investigative dermatology. 2024 May 17

Saha A, Palchaudhuri R, Lanieri L, Hyzy S, Riddle MJ, Panthera J, Eide CR, Jakub Tolar, Panoskaltsis-Mortari A, Gorfinkel L, Tkachev V, Gerdemann U, Alvarez-Calderon F, Palato ER, MacMillan ML, Wagner JE, Kean LS, Osborn MJ, Kiem HP, Scadden DT, Olson LM, Blazar BR. Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate-conditioned Fanconi anemia mice. Blood. 2024 May 23

Zingariello CD, Mohamed Y, Jorand-Fletcher M, Wymer J, Peter B Kang, Rasmussen SA. Diagnoses of muscular dystrophy in a veterans health system. Muscle & nerve. 2024 May 23

April 2024

Vega-Sendino M, Lüttmann FF, Olbrich T, Chen Y, Kuenne C, Stein P, Tillo D, Carey GI, Zhong J, Savy V, Radonova L, Lu T, Saykali B, Kim KP, Domingo CN, Schüler L, Günther S, Bentsen M, Darko Bosnakovski, Schöler H, Michael Kyba, Maity TK, Jenkins LM, Looso M, Williams CJ, Kim J, Ruiz S. The homeobox transcription factor DUXBL controls exit from totipotency. Nature Genetics. 2024 Apr.

Siems CB, Ji Z, Jedeon Z, Schultz J, Teigen L, Allen T, John R, Estep JD, Masotti M, Alexy T, Forum Kamdar, Maharaj V, Pritzker M, Daniel Garry, Shaffer A, Cogswell R. Validation of the Minnesota Pectoralis Risk Score to predict mortality in the HeartMate 3 population. The Journal of Heart and Lung Transplantation. 2024 Apr.

Ginz HF, Paul Iaizzo, Schweikert K, Durfee WK. Long-term monitoring of stimulated lower leg skeletal muscle forces compared with voluntary contractions in myopathy patients - A five-year follow-up report on 5 adults. Journal of Bodywork and Movement Therapies. 2024 Apr.

Lee H, Molomjamts M, Roehrich H, Gudvangen S, Asuncion C, Georgieff MK, Tran P, Linda McLoon, Ingolfsland EC. Differences in Oxygen-Induced Retinopathy Susceptibility Between Two Sprague Dawley Rat Vendors: A Comparison of Retinal Transcriptomes. Current Eye Research. 2024 Apr.

Strege CL, Miller WC, Eide C, Hubbard J, Jakub Tolar. Methods for Decreasing Preweaning Mortality in a Fragile Mouse Model of Hypomorphic Collagen VII Deficiency. Comparative Medicine. 2024 Apr 1.

Sullivan BP, Collins BC, McMillin SL, Toussaint E, Stein CZ, Spangenburg EE, Dawn Lowe. Ablation of skeletal muscle estrogen receptor alpha impairs contractility in male mice. Journal of Applied Physiology (1985). 2024 Apr 1.

Crist SB, Azzag K, Kiley J, Coleman I, Magli A, Rita Perlingeiro. The adult environment promotes the transcriptional maturation of human iPSC-derived muscle grafts. NPJ Regenerative Medicine. 2024 Apr 4.

Natarajan RK, Nathan Rodgers, Narasimhan S, Ambrose M, Rothman A, Shyne M, Evans M, Aggarwal V. Invasive haemodynamics predict outcomes in paediatric pulmonary artery hypertension. Cardiology in the Young. 2024 Apr 4.

Alessandro Bartolomucci, Tung J, Harris KM. The fortunes and misfortunes of social life across the life course: A new era of research from field, laboratory and comparative studies. Neuroscience and Biobehavioral Reviews. 2024 Apr 5.

Prisco AR, Hayase J, Olson M, Brigham RC, Ramirez DA, Paul Iaizzo, Shivkumar K, Bradfield J, Tholakanahalli VN. Rate of Change of Initial Intrinsicoid Deflection Predicts Endocardial Versus Epicardial Ventricular Tachycardia. JACC. Clinical Electrophysiology. 2024 Apr 5.

Kress DJ, Morgan PM, Thomas DC, Haselhuhn JJ, David Polly Jr. Prevalence of total joint arthroplasty in the adult spine deformity population. Spine Deformity. 2024 Apr 9.

Mueller AJ, Lindsay AP, Lewis RM, Zhang Q, Narayanan S, Lodge TP, Mahanthappa MK, Frank BatesParticle Dynamics in a Diblock-Copolymer-Based Dodecagonal Quasicrystal and Its Periodic Approximant by X-Ray Photon Correlation Spectroscopy. Physical Review Letters. 2024 Apr 12.

Popp C, Miller W, Eide C, Jakub Tolar, McGrath JA, Ebens CL. Beyond the Surface: A Narrative Review Examining the Systemic Impacts of Recessive Dystrophic Epidermolysis Bullosa. The Journal of Investigative Dermatology. 2024 Apr 12.

Odland K, Chanbour H, Zuckerman SL, David Polly Jr. Spinopelvic fixation failure in the adult spinal deformity population: systematic review and meta-analysis. European Spine Journal. 2024 Apr 15.

Brigham RC, Mattson AR, Paul Iaizzo. Ventricular Epicardial Adipose Distribution on Human Hearts: 3-Dimensional Reconstructions and Quantitative Assessments. Journal of Cardiovascular Translational Research. 2024 Apr 16.

Jimenez AD, Gopaul M, Asbell H, Aydemir S, Basha MM, Batra A, Damien C, Day GS, Eka O, Eschbach K, Fatima S, Fields MC, Foreman B, Gerard EE, Gofton TE, Haider HA, Hantus ST, Hocker S, Jongeling A, Kalkach Aparicio M, Kandula P, Peter B Kang, Kazazian K, Kellogg MA, Kim M, Lee JW, Marcuse LV, McGraw CM, Mohamed W, Orozco J, Pimentel C, Punia V, Ramirez AM, Steriade C, Struck AF, Taraschenko O, Treister AK, Yoo JY, Zafar S, Zhou DJ, Zutshi D, Gaspard N, Hirsch LJ, Hanin A. Comparative analysis of patients with new onset refractory status epilepticus preceded by fever (febrile infection-related epilepsy syndrome) versus without prior fever: An interim analysis. Epilepsia. 2024 Apr 16.

Bradley Miller, Kelepouris N, Tenenbaum H, Di Carlo S, Backeljauw P. Pediatric growth hormone deficiency: Understanding the patient and caregiver perspectives. Growth Hormone & IGF Research. 2024 Apr 16.

Barr KE, Ohnsorg ML, Liberman L, Corcoran LG, Sarode A, Nagapudi K, Feder CR, Frank Bates, Reineke TM. Drug-Polymer Nanodroplet Formation and Morphology Drive Solubility Enhancement of GDC-0810. Bioconjugate Chemistry. 2024 Apr 17.

Goetze JW, Benitez C, Frank Bates, Ellison CJ. Porous Melt Blown Poly(butylene terephthalate) Fibers with High Ductility and High-Temperature Structural Stability. ACS Macro Letters. 2024 Apr 18.

Kim CH, Lamer TJ, Manda Keller-Ross, Stolen C, Johnson BD. Blunted cardiovascular responses to exercise by inhibiting afferent feedback via spinal cord stimulation in heart failure. ESC Heart Fail. 2024 Apr 18.

Klein KO, Bradley Miller, Mauras N. Unstimulated Luteinizing Hormone for Assessment of Suppression During Treatment of Central Precocious Puberty with 6-Month Subcutaneous Leuprolide Acetate: Correlations with Clinical Response. Hormone Research in Paediatrics. 2024 Apr 29.

March 2024

Nguyen T, Rosa-Garrido M, Sadek H, Daniel Garry, Zhang JJ. Promoting cardiomyocyte proliferation for myocardial regeneration in large mammals. Journal of Molecular and Cellular Cardiology. 2024 Mar.

Clark BL, Norton EM, Bamford NJ, Randhawa IAS, Kemp KL, Molly McCue, Bertin FR, Stewart AJ. Epidemiological investigation of insulin dysregulation in Shetland and Welsh ponies in Australia. Equine Veterinary Journal. 2024 Mar.

Májovská J, Nestrašil I, Ahmed A, Bondy MT, Klempíř J, Jahnová H, Schneider SA, Horáková D, Krásenský J, Ješina P, Vaneckova M, David Nascene, Whitley CB, Jarnes JR, Magner M, Dušek P. Quantitative brain morphometry identifies cerebellar, cortical, and subcortical gray and white matter atrophy in late-onset Tay-Sachs disease. Journal of Inherited Metabolic Disease. 2024 Mar.

Osha Roopnarine, David Thomas. Structural Dynamics of Protein Interactions Using Site-Directed Spin Labeling of Cysteines to Measure Distances and Rotational Dynamics with EPR Spectroscopy. Applied Magnetic Resonance. 2024 Mar.

Singh G, Sembrano JN, Haselhuhn JJ, David Polly Jr. Lumbar degenerative spondylolisthesis: role of sagittal alignment. Spine Deformity. 2024 Mar.

Jaeger D, Lafrance M, Canon V, Kosmopoulos M, Gaisendrees C, Debaty G, Demetri Yannopoulos, Hubert H, Chouihed T; GR-RéAC. Association between cardiopulmonary resuscitation duration and survival after out-of-hospital cardiac arrest according: a first nationwide study in France. Internal and Emergency Medicine. 2024 Mar.

Tahsin CT, Anselmo M, Lee E, Stokes W, Fonkoue IT, Vanden Noven ML, Carter JR, Manda Keller-Ross. Sleep disturbance and sympathetic neural reactivity in postmenopausal females. American Journal of Physiology. Heart and Circulatory Physiology. 2024 Mar 1.

Haselhuhn JJ, Odland K, Soriano PBO, Jones KE, David Polly Jr. A Novel Surgical Indication for Scheuermann's Kyphosis. Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews. 2024 Mar 5.

Blanco MJ, Bronson JJ, DiMauro EF, Dzierba C, Eggen M, Garner AL, Gunda Georg, Giarolla J, Goodwin NC, Grenier-Davies MC, Haskell-Luevano C, Holzgrabe U, Huang R, Lagiakos HR, Leftheris K, Martin Y, Matos MJ, May-Dracka TL, Müller CE, Newman AH, Parmee E, Petter JC, Tamayo NA, Wexler RR, Bolognesi ML, Ripka A, Young W. Empowering Voices: Inspiring Women in Medicinal Chemistry. ACS Medicinal Chemistry Letters. 2024 Mar 8.

Peter B Kang. Skipping, Steroids, and Genes: The First 7 Therapies for Duchenne Muscular Dystrophy. Neurology. 2024 Mar 12.

Cui S, Murphy EA, Zhang W, Zografos A, Shen L, Frank Bates, Lodge TP. Cylinders-in-Undulating-Lamellae Morphology from ABC Bottlebrush Block Terpolymers. Journal of the American Chemical Society. 2024 Mar 13.

Huang S, David Nascene, Shanley R, Pena-Pino I, Lund TC, Gupta AO, Orchard PJ, Sandoval-Garcia C. Natural history of craniovertebral abnormalities in a single-center study in 54 patients with Hurler syndrome. Journal of Neurosurgery. Pediatrics. 2024 Mar 15.

Sarah Greising, Call JA. When is the right time to initiate rehabilitation? Time will tell…. Experimental Physiology. 2024 Mar 17.

Johnson EE, Southern WM, Doud B, Steiger B, Razzoli M, Alessandro Bartolomucci, James Ervasti. Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38. Human Molecular Genetics. 2024 Mar 20.

Duvick L, Southern WM, Benzow KA, Burch ZN, Handler HP, Mitchell JS, Kuivinen H, Gadiparthi U, Yang P, Soles A, Sheeler CA, Rainwater O, Serres S, Lind EB, Nichols-Meade T, You Y, O'Callaghan B, Zoghbi HY, Cvetanovic M, Wheeler VC, Jim Ervasti, Koob MD, Harry OrrMapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease. JCI Insight. 2024 Mar 21.

February 2024

Ahmed Z, Tahmin CI, Tahsin CT, Michopoulos V, Mohamed A, Wattero R, Albott S, Cullen KR, Dawn Lowe, Osborn J, Fonkoue IT. Higher arterial stiffness and blunted vagal control of the heart in young women with compared to without a clinical diagnosis of PTSD. Clinical Autonomic Research. 2024 Feb.

Alter C, Boguszewski M, Clemmons D, Dobri GA, Geffner ME, Kelepouris N, Bradley Miller, Oh R, Shea H, Yuen KCJ. Insights from an advisory board: Facilitating transition of care into adulthood in brain cancer survivors with acquired pediatric growth hormone deficiency. Growth Hormone & IGF Research. 2024 Feb.

Brown L, Swiontkowski M, Odland K, David Polly Jr, Haselhuhn J. Effect of revision sacroiliac joint fusion on unresolved pain and disability: a retrospective cohort study. European Spine Journal. 2024 Feb.

Stevens JA, Dobratz TC, Fischer KD, Palmer A, Bourdage K, Wong AJ, Chapoy-Villanueva H, Daniel Garry, Liu JC, Kay MW, Kuzmiak-Glancy S, DeWayne TownsendMechanisms of reduced myocardial energetics of the dystrophic heart. American Journal of Physiology. Heart and Circulatory Physiology. 2024 Feb 1.

Bradley Miller, Blair J, Horikawa R, Linglart A, Yuen KCJ. Developments in the Management of Growth Hormone Deficiency: Clinical Utility of Somapacitan. Drug Design, Development and Therapy. 2024 Feb 3.

David Polly Jr. The Sacroiliac Joint: A Current State-of-the-Art Review. JBJS Reviews. 2024 Feb 5.

Barbus C, Rayannavar A, Bradley Miller, Jenkins MJ, Addo OY, Rayes A, Ahrweiler N, Olson A, Pohlkamp Z, Wagner JE, MacMillan ML. Development of specific growth charts for children with Fanconi anemia. American Journal of Medical Genetics. 2024 Feb 5.

Schneider CA, Leung JM, Valenzuela-Leon PC, Golviznina NA, Toso EA, Darko Bosnakovski, Michael Kyba, Calvo E, Peterson KE. Skin muscle is the initial site of viral replication for arboviral bunyavirus infection. Nature Communications. 2024 Feb 6.

Tejwani L, Ravindra NG, Lee C, Cheng Y, Nguyen B, Luttik K, Ni L, Zhang S, Morrison LM, Gionco J, Xiang Y, Yoon J, Ro H, Haidery F, Grijalva RM, Bae E, Kim K, Martuscello RT, Harry Orr, Zoghbi HY, McLoughlin HS, Ranum LPW, Shakkottai VG, Faust PL, Wang S, van Dijk D, Lim J. Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1. Neuron. 2024 Feb 7.

Heinis FI, Thompson BR, Gulati R, Wheelwright M, Joseph Metzger. Myofilament-based physiological regulatory compensation preserves diastolic function in failing hearts with severe Ca2+ handling deficits. JCI Insight. 2024 Feb 8

Xie N, Robinson K, Sundquist T, Sunny ChanIn vivo PSC differentiation as a platform to identify factors for improving the engraftability of cultured muscle stem cells. Frontiers in Cell and Developmental Biology. 2024 Feb 15.

Eddington C, Schwartz JK, Meg Titus. filoVision - using deep learning and tip markers to automate filopodia analysis. Journal of Cell Science. 2024 Feb 15.

Gochman A, Do TQ, Kim K, Schwarz JA, Thorpe MP, Blackwell DJ, Ritschel PA, Smith AN, Rebbeck RT, Akers WS, Razvan Cornea, Laver DR, Johnston JN, Knollmann BC. ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2-/- Mice. Molecular Pharmacology. 2024 Feb 15.

Sundby LJ, Southern WM, Sun J, Patrinostro X, Zhang W, Yong J, Jim ErvastiDeletion of exons 2 and 3 from Actb and cell immortalization lead to widespread, β-actin independent alterations in gene expression associated with cell cycle control. European Journal of Cell Biology. 2024 Feb 15.

Bedada FB, Thompson BR, Mikkila JL, Sunny Chan, Choi SH, Toso EA, Michael Kyba, Joseph MetzgerInducing positive inotropy in human iPSC-derived cardiac muscle by gene editing-based activation of the cardiac α-myosin heavy chain. Scientific Reports. 2024 Feb 16.

Kwak IY, Kim BC, Lee J, Kang T, Daniel Garry, Zhang J, Gong W. Proformer: a hybrid macaron transformer model predicts expression values from promoter sequences. BMC Bioinformatics. 2024 Feb 20.

Subrahmanian MV, Gianluigi Veglia. AI-designed RF pulses enable fast pulsing heteronuclear multiple quantum coherence NMR experiment at high and ultra-high magnetic fields. Chemical Communications. 2024 Feb 20.

Azzag K, Gransee HM, Magli A, Yamashita AMS, Tungtur S, Ahlquist A, Zhan WZ, Onyebu C, Sarah Greising, Mantilla CB, Rita Perlingeiro. Enhanced Diaphragm Muscle Function upon Satellite Cell Transplantation in Dystrophic Mice. International Journal of Molecular Sciences. 2024 Feb 21.

Ormseth AF, Odland K, Haselhuhn JJ, Holton KJ, David Polly Jr. Pelvic Fixation Construct Trends in Spinal Deformity Surgery. Indian Journal of Orthopaedics. 2024 Feb 22.

Shelton GD, James Mickelson, Friedenberg SG, Cullen JN, Graham K, Carpentier MC, Guo LT, Minor KM. Variants in CLCN1 and PDE4C Associated with Muscle Hypertrophy, Dysphagia, and Gait Abnormalities in Young French Bulldogs. Animals. 2024 Feb 25.

Motorykin I, Mu J, Bradley Miller, Li A, Clarke NJ, McPhaul MJ, Wu Z. Detection rate of IGF-1 variants and their implication to protein binding: study of over 240,000 patients. Clinical Chemistry and Laboratory Medicine. 2024 Feb 26.

January 2024

Tucker AP, Erdman AG, Schreiner PJ, Ma S, Lisa ChowNeural Networks With Gated Recurrent Units Reduce Glucose Forecasting Error Due to Changes in Sensor Location. Journal of Diabetes Science and Technology. 2024 Jan.

Nowak RJ, Breiner A, Bril V, Jeffrey Allen, Khan S, Levine T, Jacobs DH, Sahagian G, Siddiqi ZA, Xu J, Macias WL, Benatar M; ASCEND MG Study Group. Subcutaneous batoclimab in generalized myasthenia gravis: Results from a Phase 2a trial with an open-label extension. Annals of Clinical and Translational Neurology. 2024 Jan.

Foltz MH, Johnson CP, Truong W, David Polly Jr, Ellingson AM. Morphological alterations of lumbar intervertebral discs in patients with adolescent idiopathic scoliosis. The Spine Journal. 2024 Jan.

Soriano PBO, Haselhuhn JJ, Resch JC, Fischer GA, Swanson DB, Holton KJ, David Polly Jr. Postoperative use and early discontinuation of intravenous lidocaine in spine patients. Spine Deformity. 2024 Jan.

Rodriguez P, Laskowski LJ, Pallais JP, Bock HA, Cavalco NG, Anderson EI, Calkins MM, Razzoli M, Sham YY, McCorvy JD, Alessandro BartolomucciFunctional profiling of the G protein-coupled receptor C3aR1 reveals ligand-mediated biased agonism. The Journal of Biological Chemistry. 2024 Jan.

Schifino AG, Cooley MA, Zhong RX, Heo J, Hoffman DB, Warren GL, Sarah Greising, Call JA. Tibial bone strength is negatively affected by volumetric muscle loss injury to the adjacent muscle in male mice. Journal of Orthopaedic Research. 2024 Jan.

Johnson LL, Abrahante JE, Linda McLoon. Nystagmus in the B6(CG)Tyr(c-2J)/J Albino Mouse: A Functional and RNA-Seq Analysis. Investigative Ophthalmology & Visual Science. 2024 Jan 2.

Jeffrey Allen, Clarke AE, Harbo T. A Practical Guide to Identify Patients With Multifocal Motor Neuropathy, a Treatable Immune-Mediated Neuropathy. Mayo Clinic Proceedings. Innovations, Quality & Outcomes. 2024 Jan 8.

Nguyen TM, Geng X, Wei Y, Ye L, Daniel Garry, Zhang J. Single-cell RNA sequencing analysis identifies one subpopulation of endothelial cells that proliferates and another that undergoes the endothelial-mesenchymal transition in regenerating pig hearts. Frontiers in Bioengineering and Biotechnology. 2024 Jan 15.

Englund DA, Jolliffe AM, Hanson GJ, Aversa Z, Zhang X, Jiang X, White TA, Zhang L, Monroe DG, Paul Robbins, Laura Niedernhofer, Kamenecka TM, Khosla S, LeBrasseur NK. Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia. JCI Insight. 2024 Jan 23.

Lee CAA, Wu S, Chow YT, Kofman E, Williams V, Riddle M, Eide C, Ebens CL, Frank MH, Jakub Tolar, Hook KP, AlDubayan SH, Frank NY. Accelerated Aging and Microsatellite Instability in Recessive Dystrophic Epidermolysis Bullosa-Associated Cutaneous Squamous Cell Carcinoma. The Journal of investigative dermatology. 2024 Jan 23

Abdel-Karim TR, Hodges JS, Herold KC, Pruett TL, Ramanathan KV, Hering BJ, Dunn TB, Kirchner VA, Gregory Beilman, Bellin MD. Peri-Transplant Inflammation and Long-Term Diabetes Outcomes Were Not Impacted by Either Etanercept or Alpha-1-Antitrypsin Treatment in Islet Autotransplant Recipients. Transplant International. 2024 Jan 31.

Tate NM, Underwood M, Thomas-Hollands A, Minor KM, Cullen JN, Friedenberg SG, James Mickelson, Xenoulis PG, Steiner JM, Furrow E. Sequence Analysis of Six Candidate Genes in Miniature Schnauzers with Primary Hypertriglyceridemia. Genes. 2024 Jan 31.

December 2023

Benson S, Yannopoulos D, Aufderheide TP, Murray TA. Randomized controlled dose-escalation design to evaluate the safety of a novel pharmacological cardiopulmonary resuscitation strategy. Clin Trials. 2023 Dec;20(6):681-688. doi: 10.1177/17407745231188443. Epub 2023 Jul 24. PMID: 37485950.

 

Rathore G, Kang PBPediatric Neuromuscular Diseases. Pediatr Neurol. 2023 Dec;149:1-14. doi: 10.1016/j.pediatrneurol.2023.08.034. Epub 2023 Aug 29. PMID: 37757659.

 

Al Noman MA, Cuellar RAD, Kyzer JL, Chung SSW, Cheryala N, Holth TAD, Maitra S, Naqvi T, Wong HL, Schönbrunn E, Hawkinson JE, Wolgemuth DJ, Georg GIStrategies for developing retinoic acid receptor alpha-selective antagonists as novel agents for male contraception. Eur J Med Chem. 2023 Dec 5;261:115821. doi: 10.1016/j.ejmech.2023.115821. Epub 2023 Sep 25. PMID: 37776573.

 

Bovo E, Rebbeck RT, Roopnarine O, Cornea RL, Thomas DD, Zima AV. Regulation of cardiac calcium signaling by newly identified calcium pump modulators. Biochem Biophys Res Commun. 2023 Dec 10;685:149136. doi: 10.1016/j.bbrc.2023.149136. Epub 2023 Oct 19. PMID: 37907012.

 

Gonzalez-Martin P, Sacco F, Butakoff C, Doste R, Bederian C, Gutierrez Espinosa de Los Monteros LK, Houzeaux G, Iaizzo PA, Iles TL, Vazquez M, Aguado-Sierra J. Ventricular anatomical complexity and sex differences impact predictions from electrophysiological computational models. PLoS One. 2023 Feb 13;18(2):e0263639. doi: 10.1371/journal.pone.0263639. PMID: 36780442; PMCID: PMC9925004.

 

Switalla K, Sundlof M, Abdelwahab H, Leslie D, Wise E, Wang Q, Duval S, Benner A, Bartolomucci A, Ikramuddin S. Effect of beta-blocker therapy on weight loss outcomes after sleeve gastrectomy & Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2023 Dec;19(12):1415-1420. doi: 10.1016/j.soard.2023.09.016. Epub 2023 Oct 27. PMID: 37925321.

 

Vunnam N, Young MC, Liao EE, Lo CH, Huber E, Been M, Thomas DD, Sachs JN. Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †. Cancer Biol Ther. 2023 Dec 31;24(1):2176692. doi: 10.1080/15384047.2023.2176692. PMID: 36775838; PMCID: PMC9928464.

November 2023

Baumann CW, Deane CS, Etheridge T, Szewczyk NJ, Willis CRG, Lowe DAAdaptability to eccentric exercise training is diminished with age in female mice. J Appl Physiol (1985). 2023 Nov 1;135(5):1135-1145. doi: 10.1152/japplphysiol.00428.2023. Epub 2023 Oct 12. PMID: 37823203.

 

Fritz-Laylin LK, Titus MA. The evolution and diversity of actin-dependent cell migration. Mol Biol Cell. 2023 Nov 1;34(12):pe6. doi: 10.1091/mbc.E22-08-0358. PMID: 37906436.

 

Homer CJ, Haselhuhn JJ, Ellingson AM, Bechtold JE, Polly DW JrDevelopment of a sacral fracture model to demonstrate effects on sagittal alignment. Spine Deform. 2023 Nov;11(6):1325-1333. doi: 10.1007/s43390-023-00721-x. Epub 2023 Jun 29. PMID: 37382877.

 

Huang Y, Hertzel AV, Fish SR, Halley CL, Bohm EK, Martinez HM, Durfee CC, Sanders MA, Harris RS, Niedernhofer LJ, Bernlohr DA. TP53/p53 Facilitates Stress-Induced Exosome and Protein Secretion by Adipocytes. Diabetes. 2023 Nov 1;72(11):1560-1573. doi: 10.2337/db22-1027. PMID: 37347719; PMCID: PMC10588298.

 

Liu H, Simonian NT, Pouch AM, Iaizzo PA, Gorman JH, Gorman RC, Sacks MS. A Computational Pipeline for Patient-Specific Prediction of the Postoperative Mitral Valve Functional State. J Biomech Eng. 2023 Nov 1;145(11):111002. doi: 10.1115/1.4062849. PMID: 37382900; PMCID: PMC10405284.

 

Nates JL, Oropello JM, Badjatia N, Beilman G, Coopersmith CM, Halpern NA, Herr DL, Jacobi J, Kahn R, Leung S, Puri N, Sen A, Pastores SM; Academic Leaders in Critical Care Task Force (ALCCM) of the Society of Critical Care Medicine. Flow-Sizing Critical Care Resources. Crit Care Med. 2023 Nov 1;51(11):1552-1565. doi: 10.1097/CCM.0000000000005967. Epub 2023 Jun 14. PMID: 37486677.

 

Shameem M, Bagherpoor AJ, Nakhi A, Dosa P, Georg G, Kassie F. Mitochondria-targeted metformin (mitomet) inhibits lung cancer in cellular models and in mice by enhancing the generation of reactive oxygen species. Mol Carcinog. 2023 Nov;62(11):1619-1629. doi: 10.1002/mc.23603. Epub 2023 Jul 4. PMID: 37401866.

 

Pendleton EG, Nichenko AS, Mcfaline-Figueroa J, Raymond-Pope CJ, Schifino AG, Pigg TM, Barrow RP, Greising SM, Call JA, Mortensen LJ. Compromised Muscle Properties in a Severe Hypophosphatasia Murine Model. Int J Mol Sci. 2023 Nov 2;24(21):15905. doi: 10.3390/ijms242115905. PMID: 37958888; PMCID: PMC10649932.

 

Cuellar ME, Yang M, Karavadhi S, Zhang YQ, Zhu H, Sun H, Shen M, Hall MD, Patnaik S, Ashe KH, Walters MA, Pockes S. An electrophilic fragment screening for the development of small molecules targeting caspase-2. Eur J Med Chem. 2023 Nov 5;259:115632. doi: 10.1016/j.ejmech.2023.115632. Epub 2023 Jul 11. PMID: 37453329; PMCID: PMC10529632.

 

Jaeger D, Kosmopoulos M, Voicu S, Kalra R, Gaisendrees C, Schlartenberger G, Bartos JA, Yannopoulos D. Cerebral hemodynamic effects of head-up CPR in a porcine model. Resuscitation. 2023 Nov 5;193:110039. doi: 10.1016/j.resuscitation.2023.110039. Epub ahead of print. PMID: 37935278.

 

Komosa ER, Lin WH, Mahadik B, Bazzi MS, Townsend D, Fisher JP, Ogle BM. A novel perfusion bioreactor promotes the expansion of pluripotent stem cells in a 3D-bioprinted tissue chamber. Biofabrication. 2023 Nov 10;16(1):014101. doi: 10.1088/1758-5090/ad084a. PMID: 37906964; PMCID: PMC10636629.

 

Siems CB, Ji Z, Jedeon Z, Schultz J, Teigen L, Allen T, John R, Estep JD, Masotti M, Alexy T, Kamdar F, Maharaj V, Pritzker M, Garry D, Shaffer A, Cogswell R. Validation of the Minnesota Pectoralis Risk Score to predict mortality in the HeartMate 3 population. J Heart Lung Transplant. 2023 Nov 11:S1053-2498(23)02121-6. doi: 10.1016/j.healun.2023.11.003. Epub ahead of print. PMID: 37956881.

 

Kirchner VA, Badshah JS, Hong SK, Martinez O, Pruett TL, Niedernhofer LJEffect of Cellular Senescence in Disease Progression and Transplantation: Immune Cells and Solid Organs. Transplantation. 2023 Nov 13. doi: 10.1097/TP.0000000000004838. Epub ahead of print. PMID: 37953486.

 

Thompson LM, Orr HTHD and SCA1: Tales from two 30-year journeys since gene discovery. Neuron. 2023 Nov 15;111(22):3517-3530. doi: 10.1016/j.neuron.2023.09.036. Epub 2023 Oct 19. PMID: 37863037.

 

Garry DJ, Zhang JJ, Larson TA, Sadek HA, Garry MGNetworks that Govern Cardiomyocyte Proliferation to Facilitate Repair of the Injured Mammalian Heart. Methodist Debakey Cardiovasc J. 2023 Nov 16;19(5):16-25. doi: 10.14797/mdcvj.1300. PMID: 38028968; PMCID: PMC10655759.

 

Menendez-Montes I, Garry DJ, Zhang JJ, Sadek HA. Metabolic Control of Cardiomyocyte Cell Cycle. Methodist Debakey Cardiovasc J. 2023 Nov 16;19(5):26-36. doi: 10.14797/mdcvj.1309. PMID: 38028975; PMCID: PMC10655756.

 

Tejwani L, Ravindra NG, Lee C, Cheng Y, Nguyen B, Luttik K, Ni L, Zhang S, Morrison LM, Gionco J, Xiang Y, Yoon J, Ro H, Haidery F, Grijalva RM, Bae E, Kim K, Martuscello RT, Orr HT, Zoghbi HY, McLoughlin HS, Ranum LPW, Shakkottai VG, Faust PL, Wang S, van Dijk D, Lim J. Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1. Neuron. 2023 Nov 16:S0896-6273(23)00844-9. doi: 10.1016/j.neuron.2023.10.039. Epub ahead of print. PMID: 38016472.

 

Clemens PR, Gordish-Dressman H, Niizawa G, Gorni K, Guglieri M, Connolly AM, Wicklund M, Bertorini T, Mah J, Thangarajh M, Smith EC, Kuntz NL, McDonald CM, Henricson E, Upadhyayula S, Byrne B, Manousakis G, Harper A, Iannaccone S, Dang UJ. Findings from the Longitudinal CINRG Becker Natural History Study. J Neuromuscul Dis. 2023 Nov 17. doi: 10.3233/JND-230178. Epub ahead of print. PMID: 37980682.

 

Gathman TJ, Vasdev RMS, Smetak MR, Williams A, Budde A, Iaizzo PAJoint engineering-medical school programs prepare physicians for clinical challenges: An observational study. Health Sci Rep. 2023 Nov 17;6(11):e1704. doi: 10.1002/hsr2.1704. PMID: 38028705; PMCID: PMC10655514.

 

Miller BS, Blair JC, Rasmussen MH, Maniatis A, Mori J, Böttcher V, Kim HS, Bang RB, Polak M, Horikawa R. Effective GH Replacement With Somapacitan in Children With GHD: REAL4 2-year Results and After Switch From Daily GH. J Clin Endocrinol Metab. 2023 Nov 17;108(12):3090-3099. doi: 10.1210/clinem/dgad394. Erratum in: J Clin Endocrinol Metab. 2023 Aug 24;: PMID: 37406251; PMCID: PMC10655534.

 

Castro-Pearson S, Samorodnitsky S, Yang K, Lotfi-Emran S, Ingraham NE, Bramante C, Jones EK, Greising S, Yu M, Steffen B, Svensson J, Åhlberg E, Österberg B, Wacker D, Guan W, Puskarich M, Smed-Sörensen A, Lusczek E, Safo SE, Tignanelli CJ. Development of a proteomic signature associated with severe disease for patients with COVID-19 using data from 5 multicenter, randomized, controlled, and prospective studies. Sci Rep. 2023 Nov 20;13(1):20315. doi: 10.1038/s41598-023-46343-1. PMID: 37985892; PMCID: PMC10661735.

October 2023

Huang S, Gupta A, Orchard P, Lund T, Nascene DVenous Sinus Stenosis with Prominent Emissary Veins: A New Common Cranial MRI Finding of Mucopolysaccharidosis I. AJNR Am J Neuroradiol. 2023 Oct;44(10):1236-1239. doi: 10.3174/ajnr.A7997. Epub 2023 Sep 7. PMID: 37679022; PMCID: PMC10549949.

 

Karachunski P, Townsend DSystemic under treatment of heart disease in patients with Duchenne muscular dystrophy. Neuromuscul Disord. 2023 Oct;33(10):776-781. doi: 10.1016/j.nmd.2023.09.004. Epub 2023 Sep 19. PMID: 37775424.

 

Lyons CE, Razzoli M, Bartolomucci AThe impact of life stress on hallmarks of aging and accelerated senescence: Connections in sickness and in health. Neurosci Biobehav Rev. 2023 Oct;153:105359. doi: 10.1016/j.neubiorev.2023.105359. Epub 2023 Aug 15. PMID: 37586578; PMCID: PMC10592082.

 

Polly DW Jr, Haselhuhn JJ, Soriano PBO, Odland K, Jones KE. Management of High-Grade Dysplastic Spondylolisthesis. Neurosurg Clin N Am. 2023 Oct;34(4):567-572. doi: 10.1016/j.nec.2023.06.003. Epub 2023 Jul 23. PMID: 37718103.

 

Raymond-Pope CJ, Hoffman DB, Bloxsom RM, Greising SM, Novacheck TF, Boyer ER. Medial Gastrocnemius Muscle Properties of Children With Cerebral Palsy After Different Tone Treatments: A Pilot Study. Am J Phys Med Rehabil. 2023 Oct 1;102(10):873-878. doi: 10.1097/PHM.0000000000002235. Epub 2023 Mar 8. PMID: 36897794; PMCID: PMC10485173.

 

Sahu BS, Razzoli M, McGonigle S, Pallais JP, Nguyen ME, Sadahiro M, Jiang C, Lin WJ, Kelley KA, Rodriguez P, Mansk R, Cero C, Caviola G, Palanza P, Rao L, Beetch M, Alejandro E, Sham YY, Frontini A, Salton SR, Bartolomucci ATargeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis. Mol Metab. 2023 Oct;76:101781. doi: 10.1016/j.molmet.2023.101781. Epub 2023 Jul 21. PMID: 37482186; PMCID: PMC10400922.

 

Schifino AG, Raymond-Pope CJ, Heo J, McFaline-Figueroa J, Call JA, Greising SMResistance wheel running improves contractile strength, but not metabolic capacity, in a murine model of volumetric muscle loss injury. Exp Physiol. 2023 Oct;108(10):1282-1294. doi: 10.1113/EP091284. Epub 2023 Aug 10. PMID: 37526646; PMCID: PMC10543535.

 

Tahsin CT, Michopoulos V, Powers A, Park J, Ahmed Z, Cullen K, Jenkins NDM, Keller-Ross M, Fonkoue IT. Sleep efficiency and PTSD symptom severity predict microvascular endothelial function and arterial stiffness in young, trauma-exposed women. Am J Physiol Heart Circ Physiol. 2023 Oct 1;325(4):H739-H750. doi: 10.1152/ajpheart.00169.2023. Epub 2023 Jul 28. PMID: 37505472; PMCID: PMC10642999.

 

Vanden Noven ML, Anselmo M, Tahsin CT, Carter JR, Keller-Ross MLA review of the historical use of sex as a biological variable in the American Journal of Physiology-Heart and Circulatory Physiology. Am J Physiol Heart Circ Physiol. 2023 Oct 1;325(4):H768-H773. doi: 10.1152/ajpheart.00278.2023. Epub 2023 Aug 18. PMID: 37594486; PMCID: PMC10643001.

 

Pavlou V, Cienfuegos S, Lin S, Ezpeleta M, Ready K, Corapi S, Wu J, Lopez J, Gabel K, Tussing-Humphreys L, Oddo VM, Alexandria SJ, Sanchez J, Unterman T, Chow LS, Vidmar AP, Varady KA. Effect of Time-Restricted Eating on Weight Loss in Adults With Type 2 Diabetes: A Randomized Clinical Trial. JAMA Netw Open. 2023 Oct 2;6(10):e2339337. doi: 10.1001/jamanetworkopen.2023.39337. PMID: 37889487; PMCID: PMC10611992.

 

Lyons CE, Graves SI, Razzoli M, Jeganathan K, Mansk RP, McGonigle S, Sabarinathan N, van Deursen JM, Baker DJ, Bartolomucci AChronic social and psychological stress impact select neuropathologies in the PS19 mouse model of tauopathy. Psychosom Med. 2023 Oct 3. doi: 10.1097/PSY.0000000000001256. Epub ahead of print. PMID: 37910129.

 

Record CJ, Skorupinska M, Laura M, Rossor AM, Pareyson D, Pisciotta C, Feely SME, Lloyd TE, Horvath R, Sadjadi R, Herrmann DN, Li J, Walk D, Yum SW, Lewis RA, Day J, Burns J, Finkel RS, Saporta MA, Ramchandren S, Weiss MD, Acsadi G, Fridman V, Muntoni F, Poh R, Polke JM, Zuchner S, Shy ME, Scherer SS, Reilly MM; Inherited Neuropathies Consortium—Rare Disease Clinical Research Network. Genetic analysis and natural history of Charcot-Marie-Tooth disease CMTX1 due to GJB1 variants. Brain. 2023 Oct 3;146(10):4336-4349. doi: 10.1093/brain/awad187. PMID: 37284795; PMCID: PMC10545504.

 

Rotella DP, Georg GPatrick M. Woster Memorial Commentary. ACS Med Chem Lett. 2023 Oct 3;14(10):1305-1309. doi: 10.1021/acsmedchemlett.3c00382. PMID: 37849535; PMCID: PMC10577880.

 

Motorykin I, Mu J, Miller BS, Li A, Clarke NJ, McPhaul MJ, Wu Z. Detection rate of IGF-1 variants and their implication to protein binding: study of over 240,000 patients. Clin Chem Lab Med. 2023 Oct 10. doi: 10.1515/cclm-2023-0709. Epub ahead of print. PMID: 37811857.

 

Wang X, Larson AN, Polly DW Jr, Aubin CE. Biomechanical Computational Study of Pedicle Screw Position and Density in Adolescent Idiopathic Scoliosis Instrumentation. Spine (Phila Pa 1976). 2023 Oct 15;48(20):1436-1445. doi: 10.1097/BRS.0000000000004742. Epub 2023 Jun 8. PMID: 37294810.

 

Gomez R, Lamoureux R, Turner-Bowker DM, Loftus J, Maghnie M, Miller BS, Polak M, Yaworsky A. Physician experience with once-weekly somatrogon versus once-daily rhGH regimen in pediatric patients with growth hormone deficiency: a cross-sectional survey of physicians from the global phase 3 study. Front Endocrinol (Lausanne). 2023 Oct 17;14:1254424. doi: 10.3389/fendo.2023.1254424. PMID: 37955005; PMCID: PMC10634585.

 

Henry RK, Miller BSApproach to the Patient: Case Studies in Pediatric Growth Hormone Deficiency and Their Management. J Clin Endocrinol Metab. 2023 Oct 18;108(11):3009-3021. doi: 10.1210/clinem/dgad305. PMID: 37246615.

 

Bunch TA, Guhathakurta P, Thompson AR, Lepak VC, Carter AL, Thomas JJ, Thomas DD, Colson BA. Drug discovery for heart failure targeting myosin-binding protein C. J Biol Chem. 2023 Oct 20;299(12):105369. doi: 10.1016/j.jbc.2023.105369. Epub ahead of print. PMID: 37865311.

 

Šeflová J, Schwarz JA, Smith AN, Svensson B, Blackwell DJ, Phillips TA, Nikolaienko R, Bovo E, Rebbeck RT, Zima AV, Thomas DD, Van Petegem F, Knollmann BC, Johnston JN, Robia SL, Cornea RLRyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET. ACS Chem Biol. 2023 Oct 20;18(10):2290-2299. doi: 10.1021/acschembio.3c00376. Epub 2023 Sep 28. PMID: 37769131.

 

Samant S, Bakhos JJ, Wu W, Zhao S, Kassab GS, Khan B, Panagopoulos A, Makadia J, Oguz UM, Banga A, Fayaz M, Glass W, Chiastra C, Burzotta F, LaDisa JF Jr, Iaizzo P, Murasato Y, Dubini G, Migliavacca F, Mickley T, Bicek A, Fontana J, West NEJ, Mortier P, Boyers PJ, Gold JP, Anderson DR, Tcheng JE, Windle JR, Samady H, Jaffer FA, Desai NR, Lansky A, Mena-Hurtado C, Abbott D, Brilakis ES, Lassen JF, Louvard Y, Stankovic G, Serruys PW, Velazquez E, Elias P, Bhatt DL, Dangas G, Chatzizisis YS. Artificial Intelligence, Computational Simulations, and Extended Reality in Cardiovascular Interventions. JACC Cardiovasc Interv. 2023 Oct 23;16(20):2479-2497. doi: 10.1016/j.jcin.2023.07.022. PMID: 37879802.

 

Pacak CA, Suzuki-Hatano S, Khadir F, Daugherty AL, Sriramvenugopal M, Gosiker BJ, Kang PB, Cade WT. One episode of low intensity aerobic exercise prior to systemic AAV9 administration augments transgene delivery to the heart and skeletal muscle. J Transl Med. 2023 Oct 24;21(1):748. doi: 10.1186/s12967-023-04626-1. PMID: 37875924; PMCID: PMC10598899.

 

Heo J, Schifino AG, McFaline-Figueroa J, Miller DL, Hoffman JR, Noble EE, Greising SM, Call JA. Differential effects of Western diet and traumatic muscle injury on skeletal muscle metabolic regulation in male and female mice. J Cachexia Sarcopenia Muscle. 2023 Oct 25. doi: 10.1002/jcsm.13361. Epub ahead of print. PMID: 37879629.

 

Tkáč I, Xie T, Shah N, Larson S, Dubinsky JM, Gomez-Pastor R, McLoughlin HS, Orr HT, Eberly LE, Öz G. Regional sex differences in neurochemical profiles of healthy mice measured by magnetic resonance spectroscopy at 9.4 tesla. Front Neurosci. 2023 Oct 25;17:1278828. doi: 10.3389/fnins.2023.1278828. PMID: 37954878; PMCID: PMC10634209.

 

Hoffmann MD, Zdechlik AC, He Y, Nedrud D, Aslanidi G, Gordon W, Schmidt D. Multiparametric domain insertional profiling of adeno-associated virus VP1. Mol Ther Methods Clin Dev. 2023 Oct 26;31:101143. doi: 10.1016/j.omtm.2023.101143. PMID: 38027057; PMCID: PMC10661864.

 

Jaeger D, Lafrance M, Canon V, Kosmopoulos M, Gaisendrees C, Debaty G, Yannopoulos D, Hubert H, Chouihed T; GR-RéAC. Association between cardiopulmonary resuscitation duration and survival after out-of-hospital cardiac arrest according: a first nationwide study in France. Intern Emerg Med. 2023 Oct 29. doi: 10.1007/s11739-023-03449-8. Epub ahead of print. PMID: 37898966.

September 2023

Dieter K, Niebergall-Roth E, Daniele C, Fluhr S, Frank NY, Ganss C, Kiritsi D, McGrath JA, Tolar J, Frank MH, Kluth MA. Corrigendum to ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa [Cytotherapy 25 (2023) 782-788/1562]. Cytotherapy. 2023 Sep;25(9):1016. doi: 10.1016/j.jcyt.2023.06.001. Erratum for: Cytotherapy. 2023 Jul;25(7):782-788. PMID: 37517864; PMCID: PMC10581616.

 

Downs EM, Eaton A, Witkowski P, Wijkstrom M, Walsh M, Trikudanathan G, Singh VK, Schwarzenberg SJ, Pruett TL, Posselt A, Naziruddin B, Nathan JD, Mokshagundam SP, Morgan K, Lara LF, Gardner TB, Freeman ML, Ellery K, Chinnakotla S, Beilman GJ, Adams D, Ahmad S, Abu-El-Haija M, Bellin MD. Nutritional Risks in Patients Undergoing Total Pancreatectomy Islet AutoTransplantation in the POST Consortium. J Gastrointest Surg. 2023 Sep;27(9):1893-1902. doi: 10.1007/s11605-023-05770-1. Epub 2023 Jul 13. PMID: 37442881.

 

Huang S, Beatty ZJ, Mckinney AM, Nascene DRIncreased pituitary volumes in patients with Sanfilippo syndrome (mucopolysaccharidosis type 3, MPS III). Neuroradiology. 2023 Sep;65(9):1381-1386. doi: 10.1007/s00234-023-03157-2. Epub 2023 May 2. PMID: 37127720.

 

Johnson LL, Hebert S, Kueppers RB, McLoon LKNystagmus Associated With the Absence of MYOD Expression Across the Lifespan in Extraocular and Limb Muscles. Invest Ophthalmol Vis Sci. 2023 Sep 1;64(12):24. doi: 10.1167/iovs.64.12.24. PMID: 37703038; PMCID: PMC10503593.

 

Bosnakovski D, Toso EA, Ener ET, Gearhart MD, Yin L, Lüttmann FF, Magli A, Shi K, Kim J, Aihara H, Kyba MAntagonism among DUX family members evolved from an ancestral toxic single homeodomain protein. iScience. 2023 Sep 2;26(10):107823. doi: 10.1016/j.isci.2023.107823. PMID: 37744032; PMCID: PMC10514451.

 

Kyba M, Bosnakovski DFacioscapulohumeral muscular dystrophy's game of homeodomains: therapy wants a biomarker as a sword wants a whetstone. Brain Commun. 2023 Sep 2;5(5):fcad235. doi: 10.1093/braincomms/fcad235. PMID: 37731901; PMCID: PMC10507743.

 

Kildemoes RJ, Backeljauw PF, Højby M, Blair JC, Miller BS, Mori J, Lyauk YK. Model-Based Analysis of IGF-I Response, Dosing, and Monitoring for Once-Weekly Somapacitan in Children With GH Deficiency. J Endocr Soc. 2023 Sep 11;7(11):bvad115. doi: 10.1210/jendso/bvad115. PMID: 37818403; PMCID: PMC10561011.

 

Ding K, Wang S, Georg GI, Portoghese PS, Lindsley CW. In Memory of Professor Hualiang Jiang. J Med Chem. 2023 Sep 14;66(17):11589-11590. doi: 10.1021/acs.jmedchem.3c01378. Epub 2023 Aug 30. PMID: 37646574.

 

Gorbaty B, Arango S, Buyck D, James RC, Porter ST, Iaizzo P, Perry TE, Seslar S. Virtual Reality-based Methods for Training Novice Electrophysiology Trainees-A Pilot Study. J Innov Card Rhythm Manag. 2023 Sep 15;14(9):5583-5599. doi: 10.19102/icrm.2023.14091. PMID: 37781721; PMCID: PMC10540881.

 

Rotella DP, Georg GPatrick M. Woster Memorial Commentary. J Med Chem. 2023 Sep 28;66(18):12645-12649. doi: 10.1021/acs.jmedchem.3c01592. Epub 2023 Sep 8. PMID: 37681287.

August 2023

Chapoy Villanueva H, Sung JH, Stevens JA, Zhang MJ, Nelson PM, Denduluri LS, Feng F, O'Connell TD, Townsend D, Liu JC. Distinct effects of cardiac mitochondrial calcium uniporter inactivation via EMRE deletion in the short and long term. J Mol Cell Cardiol. 2023 Aug;181:33-45. doi: 10.1016/j.yjmcc.2023.05.007. Epub 2023 May 23. PMID: 37230379; PMCID: PMC10524693.

 

Mitsumoto H, Jang G, Lee I, Simmons Z, Sherman AV, Heitzman D, Sorenson E, Cheung K, Andrews J, Harms M, Shneider NA, Santella R, Paganoni S, Ajroud-Driss S, Fernandes JAM, Burke KM, Gwathmey K, Habib AA, Maragakis NJ, Walk D, Fournier C, Heiman-Patterson T, Wymer J, Diaz F, Scelsa SN, Elman L, Genge A, Goutman SA, Hayat G, Jawdat O, Johnston WS, Joyce NC, Kasarskis EJ, Kisanuki YY, Lomen-Hoerth C, Pulley MT, Shah JS, Shoesmith C, Zinman L; PLS Natural History Study Group.. Primary lateral sclerosis natural history study - planning, designing, and early enrollment. Amyotroph Lateral Scler Frontotemporal Degener. 2023 Aug;24(5-6):394-404. doi: 10.1080/21678421.2022.2161912. Epub 2022 Dec 28. PMID: 36576200.

 

Mohassel P, Yun P, Syeda S, Batra A, Bradley AJ, Donkervoort S, Monges S, Cohen JS, Leung DG, Munell F, Ortez C, Sánchez-Montáñez A, Karachunski P, Brandsema J, Medne L, Chaudhry V, Tasca G, Foley AR, Udd B, Arai AE, Walter GA, Bönnemann CG. A comprehensive study of skeletal muscle imaging in FHL1-related reducing body myopathy. Ann Clin Transl Neurol. 2023 Aug;10(8):1442-1455. doi: 10.1002/acn3.51834. Epub 2023 Jul 22. PMID: 37483011; PMCID: PMC10424657.

 

Orr HTCholecystokinin Activation of Cholecystokinin 1 Receptors: a Purkinje Cell Neuroprotective Pathway. Cerebellum. 2023 Aug;22(4):756-760. doi: 10.1007/s12311-022-01428-x. Epub 2022 Jun 23. PMID: 35733029; PMCID: PMC10307706.

 

Toh WS, Yarani R, El Andaloussi S, Cho BS, Choi C, Corteling R, De Fougerolles A, Gimona M, Herz J, Khoury M, Robbins PD, Williams D, Weiss DJ, Rohde E, Giebel B, Lim SK. A report on the International Society for Cell & Gene Therapy 2022 Scientific Signature Series, "Therapeutic advances with native and engineered human extracellular vesicles". Cytotherapy. 2023 Aug;25(8):810-814. doi: 10.1016/j.jcyt.2023.02.009. Epub 2023 Mar 15. PMID: 36931996.

 

Valenzuela TF 3rd, Iaizzo PAMultimodal Imaging of a Culotte Bifurcation Procedure in the Left Main Coronary Artery of a Perfusion-Fixed Human Heart: Step-by-Step with Serial Micro-CT Analyses. J Cardiovasc Transl Res. 2023 Aug;16(4):927-937. doi: 10.1007/s12265-023-10369-7. Epub 2023 Mar 20. PMID: 36939960; PMCID: PMC10480241.

 

Comadoll SM, Holton KJ, Polly DW Jr, Schmitz MW, Haselhuhn JJ, Soriano PBO, Martin CT, Jones KE, Sembrano JN. Chance Fracture Pattern Presenting in Proximal Junctional Failure. J Am Acad Orthop Surg Glob Res Rev. 2023 Aug 4;7(8):e23.00039. doi: 10.5435/JAAOSGlobal-D-23-00039. PMID: 37540797; PMCID: PMC10405993.

 

Bergman ZR, Kiberenge RK, Bianco R, Beilman G, Brophy CM, Hocking KM, Alvis BD, Wise ES. The Effect of Fluid Pre-loading on Vital Signs and Hemodynamic Parameters in a Porcine Model of Lipopolysaccharide-Induced Endotoxemia. Cureus. 2023 Aug 7;15(8):e43103. doi: 10.7759/cureus.43103. PMID: 37692606; PMCID: PMC10483090.

 

Cangemi S, Burzotta F, Bianchini F, DeVos A, Valenzuela T, Trani C, Aurigemma C, Romagnoli E, Lassen JF, Stankovic G, Iaizzo PAConfiguration of two-stent coronary bifurcation techniques in explanted beating hearts: the MOBBEM study. EuroIntervention. 2023 Aug 7;19(5):e423-e431. doi: 10.4244/EIJ-D-23-00063. PMID: 37171514; PMCID: PMC10397672.

 

Talukdar G, Orr HT, Lei Z. The PERK pathway: beneficial or detrimental for neurodegenerative diseases and tumor growth and cancer. Hum Mol Genet. 2023 Aug 7;32(16):2545-2557. doi: 10.1093/hmg/ddad103. PMID: 37384418; PMCID: PMC10407711.

 

Svensson B, Nitu FR, Rebbeck RT, McGurran LM, Oda T, Thomas DD, Bers DM, Cornea RLMolecular Mechanism of a FRET Biosensor for the Cardiac Ryanodine Receptor Pathologically Leaky State. Int J Mol Sci. 2023 Aug 8;24(16):12547. doi: 10.3390/ijms241612547. PMID: 37628726; PMCID: PMC10454150.

 

Bomberg EM, Miller BS, Addo OY, Rogol AD, Jaber MM, Sarafoglou K. Sex non-specific growth charts and potential clinical implications in the care of transgender youth. Front Endocrinol (Lausanne). 2023 Aug 11;14:1227886. doi: 10.3389/fendo.2023.1227886. PMID: 37635973; PMCID: PMC10455911.

 

Peyton MP, Yang TY, Higgins L, Markowski TW, Murray K, Vue C, Parker LL, Lowe DANatural aging and ovariectomy induces parallel phosphoproteomic alterations in skeletal muscle of female mice. Aging (Albany NY). 2023 Aug 14;15(15):7362-7380. doi: 10.18632/aging.204959. Epub 2023 Aug 14. PMID: 37580837; PMCID: PMC10457050.

 

Schiava M, Ikenaga C, Topf A, Caballero-Ávila M, Chou TF, Li S, Wang F, Daw J, Stojkovic T, Villar-Quiles R, Nishino I, Inoue M, Nishimori Y, Saito Y, Katsuno M, Noda S, Ito C, Otsuka M, Nahir S, Manousakis G, Walk D, Quinn C, Alfano L, Sahenk Z, Tasca G, Monforte M, Sabatelli M, Bisogni G, Oldfors A, Rydeliu A, Pal E, Paradas C, Velez B, De Bleecker JL, Farugia ME, Longman C, Harms MB, Ralston S, Zanoteli E, Macedo Serafim da Silva A, Sotoca J, Juntas-Morales R, Bevilacqua J, Balart M, Talbot S, Straub V, Guglieri M, Marini-Bettolo C, Diaz-Manera J, Weihl CC. Clinical Classification of Variants in the Valosin-Containing Protein Gene Associated With Multisystem Proteinopathy. Neurol Genet. 2023 Aug 15;9(5):e200093. doi: 10.1212/NXG.0000000000200093. PMID: 37588275; PMCID: PMC10427110.

 

Haselhuhn JJ, Mercado A, Soriano PBO, Polly DW JrHalo Formation and Resolution at 7-Year Follow-Up After Sacroiliac Joint Fusion Revision: A Case Report. JBJS Case Connect. 2023 Aug 17;13(3). doi: 10.2106/JBJS.CC.23.00199. PMID: 37590559.

 

Foltz MH, Johnson CP, Truong W, Polly DW Jr, Ellingson AM. Morphological alterations of lumbar intervertebral discs in patients with adolescent idiopathic scoliosis. Spine J. 2023 Aug 21:S1529-9430(23)03350-8. doi: 10.1016/j.spinee.2023.08.012. Epub ahead of print. PMID: 37611875.

 

Stino AM, Elsheikh B, Allen JAAnti-myelin-associated glycoprotein neuropathy: Where do we stand? Muscle Nerve. 2023 Nov;68(6):823-832. doi: 10.1002/mus.27954. Epub 2023 Aug 21. PMID: 37602932.

 

Shen L, Gorbea GD, Danielson E, Cui S, Ellison CJ, Bates FSThreading-the-Needle: Compatibilization of HDPE/iPP blends with butadiene-derived polyolefin block copolymers. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2301352120. doi: 10.1073/pnas.2301352120. Epub 2023 Aug 14. PMID: 37579167; PMCID: PMC10450653.

 

Soriano PBO, Haselhuhn JJ, Resch JC, Fischer GA, Swanson DB, Holton KJ, Polly DW JrPostoperative use and early discontinuation of intravenous lidocaine in spine patients. Spine Deform. 2023 Aug 23. doi: 10.1007/s43390-023-00753-3. Epub ahead of print. PMID: 37610553.

 

Atang AE, Rebbeck RT, Thomas DD, Avery AW. Cardiomyopathy-associated variants alter the structure and function of the α-actinin-2 actin-binding domain. Biochem Biophys Res Commun. 2023 Aug 30;670:12-18. doi: 10.1016/j.bbrc.2023.05.050. Epub 2023 May 27. PMID: 37271035.

 

Doman JL, Pandey S, Neugebauer ME, An M, Davis JR, Randolph PB, McElroy A, Gao XD, Raguram A, Richter MF, Everette KA, Banskota S, Tian K, Tao YA, Tolar J, Osborn MJ, Liu DR. Phage-assisted evolution and protein engineering yield compact, efficient prime editors. Cell. 2023 Aug 31;186(18):3983-4002.e26. doi: 10.1016/j.cell.2023.07.039. PMID: 37657419; PMCID: PMC10482982.

 

Schweitzer GG, Ditzenberger GL, Hughey CC, Finck BN, Martino MR, Pacak CA, Byrne BJ, Cade WT. Elevated liver glycogenolysis mediates higher blood glucose during acute exercise in Barth syndrome. PLoS One. 2023 Aug 31;18(8):e0290832. doi: 10.1371/journal.pone.0290832. PMID: 37651450; PMCID: PMC10470866.

July 2023

Arango S, Gorbaty B, Brigham J, Iaizzo PA, Perry TE. A role for ultra-high resolution three-dimensional printed human heart models. Echocardiography. 2023 Jul;40(7):703-710. doi: 10.1111/echo.15637. Epub 2023 Jun 22. PMID: 37345442.

 

Dieter K, Niebergall-Roth E, Daniele C, Fluhr S, Frank NY, Ganss C, Kiritsi D, McGrath JA, Tolar J, Frank MH, Kluth MA. ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa. Cytotherapy. 2023 Jul;25(7):782-788. doi: 10.1016/j.jcyt.2023.01.015. Epub 2023 Mar 1. Erratum in: Cytotherapy. 2023 Sep;25(9):1016. PMID: 36868990; PMCID: PMC10257763.

 

Gurkar AU, Gerencser AA, Mora AL, Nelson AC, Zhang AR, Lagnado AB, Enninful A, Benz C, Furman D, Beaulieu D, Jurk D, Thompson EL, Wu F, Rodriguez F, Barthel G, Chen H, Phatnani H, Heckenbach I, Chuang JH, Horrell J, Petrescu J, Alder JK, Lee JH, Niedernhofer LJ, Kumar M, Königshoff M, Bueno M, Sokka M, Scheibye-Knudsen M, Neretti N, Eickelberg O, Adams PD, Hu Q, Zhu Q, Porritt RA, Dong R, Peters S, Victorelli S, Pengo T, Khaliullin T, Suryadevara V, Fu X, Bar-Joseph Z, Ji Z, Passos JF. Spatial mapping of cellular senescence: emerging challenges and opportunities. Nat Aging. 2023 Jul;3(7):776-790. doi: 10.1038/s43587-023-00446-6. Epub 2023 Jul 3. PMID: 37400722; PMCID: PMC10505496.

 

Hoffman DB, Basten AM, Sorensen JR, Raymond-Pope CJ, Lillquist TJ, Call JA, Corona BT, Greising SM. Response of terminal Schwann cells following volumetric muscle loss injury. Exp Neurol. 2023 Jul;365:114431. doi: 10.1016/j.expneurol.2023.114431. Epub 2023 May 2. PMID: 37142114; PMCID: PMC10227691.

 

Kim K, Blackwell DJ, Yuen SL, Thorpe MP, Johnston JN, Cornea RL, Knollmann BC. The selective RyR2 inhibitor ent-verticilide suppresses atrial fibrillation susceptibility caused by Pitx2 deficiency. J Mol Cell Cardiol. 2023 Jul;180:1-9. doi: 10.1016/j.yjmcc.2023.04.005. Epub 2023 Apr 18. PMID: 37080450; PMCID: PMC10330243.

 

Kyzer JL, Noman MAA, Cuellar RAD, Chung SSW, Maitra S, Naqvi T, Hawkinson JE, Wolgemuth DJ, Georg GI. Investigation of selective retinoic acid receptor alpha antagonist ER-50891 and related analogs for male contraception. Arch Pharm (Weinheim). 2023 Jul;356(7):e2300031. doi: 10.1002/ardp.202300031. Epub 2023 May 8. PMID: 37154197.

 

Miller BS, Fung EB, White KK, Lund TC, Harmatz P, Orchard PJ, Whitley CB, Polgreen LE. Persistent bone and joint disease despite current treatments for mucopolysaccharidosis types I, II, and VI: Data from a 10-year prospective study. J Inherit Metab Dis. 2023 Jul;46(4):695-704. doi: 10.1002/jimd.12598. Epub 2023 Mar 6. PMID: 36840680.

 

Naresh-Babu J, Kwan KYH, Wu Y, Yilgor C, Alanay A, Cheung KMC, Polly DW Jr, Park JB, Ito M, Lenke LG, van Hooff ML, Kleuver M; AO Spine Knowledge Forum Deformity. AO Spine Adult Spinal Deformity Patient Profile: A Paradigm Shift in Comprehensive Patient Evaluation in Order to Optimize Treatment and Improve Patient Care. Global Spine J. 2023 Jul;13(6):1490-1501. doi: 10.1177/21925682211037935. Epub 2021 Aug 17. PMID: 34402318; PMCID: PMC10448102.

 

Roopnarine O, Yuen SL, Thompson AR, Roelike LN, Rebbeck RT, Bidwell PA, Aldrich CC, Cornea RL, Thomas DD. Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators. Sci Rep. 2023 Jul 1;13(1):10673. doi: 10.1038/s41598-023-37704-x. PMID: 37393380; PMCID: PMC10314922.

 

Wang W, Chen LY, Walker RF, Chow LS, Norby FL, Alonso A, Pankow JS, Lutsey PL. SGLT2 Inhibitors Are Associated With Reduced Cardiovascular Disease in Patients With Type 2 Diabetes: An Analysis of Real-World Data. Mayo Clin Proc. 2023 Jul;98(7):985-996. doi: 10.1016/j.mayocp.2023.01.023. PMID: 37419588; PMCID: PMC10348449.

 

Wexler TL, Reifschneider K, Backeljauw P, Cárdenas JF, Hoffman AR, Miller BS, Yuen KCJ. Growth Hormone Deficiency Following Traumatic Brain Injury in Pediatric and Adolescent Patients: Presentation, Treatment, and Challenges of Transitioning from Pediatric to Adult Services. J Neurotrauma. 2023 Jul;40(13-14):1274-1285. doi: 10.1089/neu.2022.0384. Epub 2023 Mar 21. PMID: 36825511; PMCID: PMC10294565.

 

Sierra-Pagan JE, Dsouza N, Das S, Larson TA, Sorensen JR, Ma X, Stan P, Wanberg EJ, Shi X, Garry MG, Gong W, Garry DJFOXK1 regulates Wnt signalling to promote cardiogenesis. Cardiovasc Res. 2023 Jul 6;119(8):1728-1739. doi: 10.1093/cvr/cvad054. PMID: 37036809; PMCID: PMC10325700.

 

Braun AR, Kochen NN, Yuen SL, Liao EE, Cornea RL, Thomas DD, Sachs JN. Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein. ASN Neuro. 2023 Jan-Dec;15:17590914231184086. doi: 10.1177/17590914231184086. PMID: 37428128; PMCID: PMC10338669.

 

Manu VS, Olivieri C, Veglia GAI-designed NMR spectroscopy RF pulses for fast acquisition at high and ultra-high magnetic fields. Nat Commun. 2023 Jul 12;14(1):4144. doi: 10.1038/s41467-023-39581-4. PMID: 37438347; PMCID: PMC10338431.

Berger A, Locatelli M, Arcila-Londono X, Hayat G, Olney N, Wymer J, Gwathmey K, Lunetta C, Heiman-Patterson T, Ajroud-Driss S, Macklin EA, Bind MA, Goslin K, Stuchiner T, Brown L, Bazan T, Regan T, Adamo A, Ferment V, Schroeder C, Somers M, Manousakis G, Faulconer K, Sinani E, Mirochnick J, Yu H, Sherman AV, Walk D; Pooled Resource Open-Access ALS Clinical Trials Consortium. The natural history of ALS: Baseline characteristics from a multicenter clinical cohort. Amyotroph Lateral Scler Frontotemporal Degener. 2023 Jul 17:1-9. doi: 10.1080/21678421.2023.2232812. Epub ahead of print. PMID: 37461167.

 

Hibbing PR, Shook RP, Panda S, Manoogian ENC, Mashek DG, Chow LSPredicting energy intake with an accelerometer-based intake-balance method. Br J Nutr. 2023 Jul 28;130(2):344-352. doi: 10.1017/S0007114522003312. Epub 2022 Oct 17. PMID: 36250527; PMCID: PMC10106530.

June 2023

Bijwadia SR, Raymond-Pope CJ, Basten AM, Lentz MT, Lillquist TJ, Call JA, Greising SMExploring skeletal muscle tolerance and whole-body metabolic effects of FDA-approved drugs in a volumetric muscle loss model. Physiol Rep. 2023 Jun;11(12):e15756. doi: 10.14814/phy2.15756. PMID: 37332022; PMCID: PMC10277213.

 

Kamdar F, Randhawa VK. Singling out the Heart: Revolutionizing Heart Failure by Harnessing Translational Technologies. J Card Fail. 2023 Jun;29(6):939-942. doi: 10.1016/j.cardfail.2023.04.005. PMID: 37321699; PMCID: PMC10275488.

 

Lee EJ, Anselmo M, Keller-Ross MLBlood pressure regulation during exercise: is age central to the problem? J Physiol. 2023 Jul;601(14):2755-2756. doi: 10.1113/JP284901. Epub 2023 Jun 1. PMID: 37232527.

 

Morales-Rosado JA, Schwab TL, Macklin-Mantia SK, Foley AR, Pinto E Vairo F, Pehlivan D, Donkervoort S, Rosenfeld JA, Boyum GE, Hu Y, Cong ATQ, Lotze TE, Mohila CA, Saade D, Bharucha-Goebel D, Chao KR, Grunseich C, Bruels CC, Littel HR, Estrella EA, Pais L, Kang PB, Zimmermann MT, Lupski JR, Lee B, Schellenberg MJ, Clark KJ, Wierenga KJ, Bönnemann CG, Klee EW. Bi-allelic variants in HMGCR cause an autosomal-recessive progressive limb-girdle muscular dystrophy. Am J Hum Genet. 2023 Jun 1;110(6):989-997. doi: 10.1016/j.ajhg.2023.04.006. Epub 2023 May 10. PMID: 37167966; PMCID: PMC10257193.

 

Zhang N, Harsch B, Zhang MJ, Gyberg DJ, Stevens JA, Wagner BM, Mendelson J, Patterson MT, Orchard DA, Healy CL, Williams JW, Townsend D, Shearer GC, Murphy KA, O'Connell TD. FFAR4 regulates cardiac oxylipin balance to promote inflammation resolution in HFpEF secondary to metabolic syndrome. J Lipid Res. 2023 Jun;64(6):100374. doi: 10.1016/j.jlr.2023.100374. Epub 2023 Apr 17. PMID: 37075982; PMCID: PMC10209340.

 

Faber EB, Sun L, Tang J, Roberts E, Ganeshkumar S, Wang N, Rasmussen D, Majumdar A, Hirsch LE, John K, Yang A, Khalid H, Hawkinson JE, Levinson NM, Chennathukuzhi V, Harki DA, Schönbrunn E, Georg GIDevelopment of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nat Commun. 2023 Jun 3;14(1):3213. doi: 10.1038/s41467-023-38732-x. PMID: 37270540; PMCID: PMC10239507.

 

Saavedra D, Añé-Kourí AL, Barzilai N, Caruso C, Cho KH, Fontana L, Franceschi C, Frasca D, Ledón N, Niedernhofer LJ, Pereira K, Robbins PD, Silva A, Suarez GM, Berghe WV, von Zglinicki T, Pawelec G, Lage A. Aging and chronic inflammation: highlights from a multidisciplinary workshop. Immun Ageing. 2023 Jun 8;20(1):25. doi: 10.1186/s12979-023-00352-w. PMID: 37291596; PMCID: PMC10248980.

 

Yuen KCJ, Johannsson G, Ho KKY, Miller BS, Bergada I, Rogol AD. Diagnosis and testing for growth hormone deficiency across the ages: a global view of the accuracy, caveats, and cut-offs for diagnosis. Endocr Connect. 2023 Jun 12;12(7):e220504. doi: 10.1530/EC-22-0504. PMID: 37052176; PMCID: PMC10305501.

 

Pisharady PK, Eberly LE, Adanyeguh IM, Manousakis G, Guliani G, Walk D, Lenglet C. Multimodal MRI improves diagnostic accuracy and sensitivity to longitudinal change in amyotrophic lateral sclerosis. Commun Med (Lond). 2023 Jun 16;3(1):84. doi: 10.1038/s43856-023-00318-5. PMID: 37328685; PMCID: PMC10276031.

 

Schifino AG, Cooley MA, Zhong RX, Heo J, Hoffman DB, Warren GL, Greising SM, Call JA. Tibial bone strength is negatively affected by volumetric muscle loss injury to the adjacent muscle in male mice. J Orthop Res. 2023 Jun 19. doi: 10.1002/jor.25643. Epub ahead of print. PMID: 37337074.

 

Zheng C, Zhang B, Bates FS, Lodge TP. Effect of poly[oligo(ethylene glycol) methyl ether methacrylate] side chain length on the brush swelling behavior in A/B/A-B ternary blends with polystyrene. Soft Matter. 2023 Jun 21;19(24):4519-4525. doi: 10.1039/d3sm00151b. PMID: 37283286.

 

Kos B, Mattison L, Ramirez D, Cindrič H, Sigg DC, Iaizzo PA, Stewart MT, Miklavčič D. Determination of lethal electric field threshold for pulsed field ablation in ex vivo perfused porcine and human hearts. Front Cardiovasc Med. 2023 Jun 23;10:1160231. doi: 10.3389/fcvm.2023.1160231. PMID: 37424913; PMCID: PMC10326317.

 

Bez Batti Angulski A, Hosny N, Cohen H, Martin AA, Hahn D, Bauer J, Metzger JMDuchenne muscular dystrophy: disease mechanism and therapeutic strategies. Front Physiol. 2023 Jun 26;14:1183101. doi: 10.3389/fphys.2023.1183101. PMID: 37435300; PMCID: PMC10330733.

 

Ma S, Alvear A, Schreiner PJ, Seaquist ER, Kirsh T, Chow LSDevelopment and Validation of an Electronic Health Record-Based Risk Assessment Tool for Hypoglycemia in Patients With Type 2 Diabetes Mellitus. J Diabetes Sci Technol. 2023 Jun 28:19322968231184497. doi: 10.1177/19322968231184497. Epub ahead of print. PMID: 37381607.

May 2023

Davidson S, Vecellio A, Flagstad I, Holton K, Bruzina A, Lender P, Trost S, Polly D JrDiscrepancy between DXA and CT-based assessment of spine bone mineral density. Spine Deform. 2023 May;11(3):677-683. doi: 10.1007/s43390-023-00646-5. Epub 2023 Feb 3. PMID: 36735159.

 

Dudkiewicz D, Zhingre Sanchez JD, Hołda J, Bolechała F, Strona M, Kopacz P, Iaizzo PA, Koziej M, Hołda MK, Konieczyńska M. Aortic valve fenestrations: Macroscopic assessment and functional anatomy study. Clin Anat. 2023 May;36(4):612-617. doi: 10.1002/ca.24002. Epub 2023 Jan 18. PMID: 36597994.

 

Neugebauer ME, Hsu A, Arbab M, Krasnow NA, McElroy AN, Pandey S, Doman JL, Huang TP, Raguram A, Banskota S, Newby GA, Tolar J, Osborn MJ, Liu DR. Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity. Nat Biotechnol. 2023 May;41(5):673-685. doi: 10.1038/s41587-022-01533-6. Epub 2022 Nov 10. PMID: 36357719; PMCID: PMC10188366.

 

Odland K, Yson S, Polly DW JrWide anatomical variability of PI normative values within an asymptomatic population: a systematic review. Spine Deform. 2023 May;11(3):559-566. doi: 10.1007/s43390-023-00649-2. Epub 2023 Feb 3. PMID: 36735158.

 

Walk D, Nicholson K, Locatelli E, Chan J, Macklin EA, Ferment V, Manousakis G, Chase M, Connolly M, Dagostino D, Hall M, Ostrow J, Pothier L, Lieberman C, Gelevski D, Randall R, Sherman AV, Steinhart E, Walker DG, Walker J, Yu H, Wills AM, Schwarzschild MA, Beukenhorst AL, Onnela JP, Berry JD, Cudkowicz ME, Paganoni S. Randomized trial of inosine for urate elevation in amyotrophic lateral sclerosis. Muscle Nerve. 2023 May;67(5):378-386. doi: 10.1002/mus.27807. Epub 2023 Mar 14. PMID: 36840949.

 

Crabtree AA, Boehnke N, Bates FS, Hackel BJ. Consequences of poly(ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts. Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2219885120. doi: 10.1073/pnas.2219885120. Epub 2023 Apr 24. PMID: 37094151; PMCID: PMC10161009.

 

Clark BL, Bamford NJ, Stewart AJ, McCue ME, Rendahl A, Bailey SR, Bertin FR, Norton EM. Evaluation of an HMGA2 variant contribution to height and basal insulin concentrations in ponies. J Vet Intern Med. 2023 May-Jun;37(3):1186-1192. doi: 10.1111/jvim.16723. Epub 2023 May 6. PMID: 37148171; PMCID: PMC10229368.

 

Samakkarnthai P, Saul D, Zhang L, Aversa Z, Doolittle ML, Sfeir JG, Kaur J, Atkinson EJ, Edwards JR, Russell GG, Pignolo RJ, Kirkland JL, Tchkonia T, Niedernhofer LJ, Monroe DG, Lebrasseur NK, Farr JN, Robbins PD, Khosla S. In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers. Aging (Albany NY). 2023 May 7;15(9):3331-3355. doi: 10.18632/aging.204701. Epub 2023 May 7. PMID: 37154858; PMCID: PMC10449299.

 

Hassan FM, Lenke LG, Berven SH, Kelly MP, Smith JS, Shaffrey CI, Dahl BT, de Kleuver M, Spruit M, Pellise F, Cheung KMC, Alanay A, Polly DW Jr, Sembrano J, Matsuyama Y, Qiu Y, Lewis SJ; AO Spine Knowledge Forum Deformity. Independent Prognostic Factors Associated With Improved Patient-Reported Outcomes in the Prospective Evaluation of Elderly Deformity Surgery (PEEDS) Study. Global Spine J. 2023 May 8:21925682231174182. doi: 10.1177/21925682231174182. Epub ahead of print. PMID: 37154697.

 

Wu R, Park J, Qian Y, Shi Z, Hu R, Yuan Y, Xiong S, Wang Z, Yan G, Ong SG, Song Q, Song Z, Mahmoud AM, Xu P, He C, Arpke RW, Kyba M, Shu G, Jiang Q, Jiang Y. Genetically prolonged beige fat in male mice confers long-lasting metabolic health. Nat Commun. 2023 May 12;14(1):2731. doi: 10.1038/s41467-023-38471-z. PMID: 37169793; PMCID: PMC10175245.

 

Hahn D, Quick JD, Thompson BR, Crabtree A, Hackel BJ, Bates FS, Metzger JMRapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers. Skelet Muscle. 2023 May 19;13(1):9. doi: 10.1186/s13395-023-00318-y. PMID: 37208786; PMCID: PMC10197332.

 

Gong W, Dsouza N, Garry DJ. SeATAC: a tool for exploring the chromatin landscape and the role of pioneer factors. Genome Biol. 2023 May 22;24(1):125. doi: 10.1186/s13059-023-02954-5. PMID: 37218013; PMCID: PMC10204251.

 

Saha R, Sanger Z, Bloom RP, Benally OJ, Wu K, Tonini D, Low WC, Keirstead SA, Netoff TI, Wang JP. Micromagnetic stimulation (µMS) dose-response of the rat sciatic nerve. J Neural Eng. 2023 May 31;20(3). doi: 10.1088/1741-2552/acd582. PMID: 37187172.

April 2023

Bigalke JA, Durocher JJ, Greenlund IM, Keller-Ross M, Carter JR. Blood pressure and muscle sympathetic nerve activity are associated with trait anxiety in humans. Am J Physiol Heart Circ Physiol. 2023 Apr 1;324(4):H494-H503. doi: 10.1152/ajpheart.00026.2023. Epub 2023 Feb 17. PMID: 36800506; PMCID: PMC10259854.

 

Eklund EA, Miller BS, Boucher AA. Thrombosis risk with estrogen use for puberty induction in congenital disorders of glycosylation. Mol Genet Metab. 2023 Apr;138(4):107562. doi: 10.1016/j.ymgme.2023.107562. Epub 2023 Mar 30. PMID: 37023501.

 

Henpita C, Vyas R, Healy CL, Kieu TL, Gurkar AU, Yousefzadeh MJ, Cui Y, Lu A, Angelini LA, O'Kelly RD, McGowan SJ, Chandrasekhar S, Vanderpool RR, Hennessy-Wack D, Ross MA, Bachman TN, McTiernan C, Pillai SPS, Ladiges W, Lavasani M, Huard J, Beer-Stolz D, St Croix CM, Watkins SC, Robbins PD, Mora AL, Kelley EE, Wang Y, O'Connell TD, Niedernhofer LJLoss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy. Aging Cell. 2023 Apr;22(4):e13782. doi: 10.1111/acel.13782. Epub 2023 Feb 3. PMID: 36734200; PMCID: PMC10086531.

 

Ladd BM, Martin CT, Sembrano JN, Jones KE, Polly DW Jr, Hunt MA. Odontoid Fracture as Proximal Junctional Failure in Patients With Multilevel Spine Fusions. Global Spine J. 2023 Apr;13(3):781-786. doi: 10.1177/21925682211008833. Epub 2021 May 11. PMID: 33973486; PMCID: PMC10240593.

 

Mantilla CB, Ermilov LG, Greising SM, Gransee HM, Zhan WZ, Sieck GC. Electrophysiological effects of BDNF and TrkB signaling at type-identified diaphragm neuromuscular junctions. J Neurophysiol. 2023 Apr 1;129(4):781-792. doi: 10.1152/jn.00015.2023. Epub 2023 Mar 8. PMID: 36883761; PMCID: PMC10069962.

 

Manu VS, Olivieri C, Veglia GWater irradiation devoid pulses enhance the sensitivity of 1H,1H nuclear Overhauser effects. J Biomol NMR. 2023 Apr;77(1-2):1-14. doi: 10.1007/s10858-022-00407-y. Epub 2022 Dec 19. PMID: 36534224.

 

Nascimento A, Bruels CC, Donkervoort S, Foley AR, Codina A, Milisenda JC, Estrella EA, Li C, Pijuan J, Draper I, Hu Y, Stafki SA, Pais LS, Ganesh VS, O'Donnell-Luria A, Syeda SB, Carrera-García L, Expósito-Escudero J, Yubero D, Martorell L, Pinal-Fernandez I, Lidov HGW, Mammen AL, Grau-Junyent JM, Ortez C, Palau F, Ghosh PS, Darras BT, Jou C, Kunkel LM, Hoenicka J, Bönnemann CG, Kang PB, Natera-de Benito D. Variants in DTNA cause a mild, dominantly inherited muscular dystrophy. Acta Neuropathol. 2023 Apr;145(4):479-496. doi: 10.1007/s00401-023-02551-7. Epub 2023 Feb 17. PMID: 36799992.

 

Olivieri C, Walker C, Veliparambil Subrahmanian M, Porcelli F, Taylor SS, Bernlohr DA, Veglia G. An NMR portrait of functional and dysfunctional allosteric cooperativity in cAMP-dependent protein kinase A. FEBS Lett. 2023 Apr;597(8):1055-1072. doi: 10.1002/1873-3468.14610. Epub 2023 Mar 26. PMID: 36892429.

 

Pockes S, Walters MA, Ashe KH. Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias. Transl Res. 2023 Apr;254:34-40. doi: 10.1016/j.trsl.2022.10.009. Epub 2022 Nov 4. PMID: 36343883; PMCID: PMC9991976.

 

Ramabadran R, Wang JH, Reyes JM, Guzman AG, Gupta S, Rosas C, Brunetti L, Gundry MC, Tovy A, Long H, Gu T, Cullen SM, Tyagi S, Rux D, Kim JJ, Kornblau SM, Kyba M, Stossi F, Rau RE, Takahashi K, Westbrook TF, Goodell MA. DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells. Nat Cell Biol. 2023 Apr;25(4):528-539. doi: 10.1038/s41556-023-01109-9. Epub 2023 Apr 6. PMID: 37024683; PMCID: PMC10337578.

 

Schmitt CA, Tchkonia T, Niedernhofer LJ, Robbins PD, Kirkland JL, Lee S. COVID-19 and cellular senescence. Nat Rev Immunol. 2023 Apr;23(4):251-263. doi: 10.1038/s41577-022-00785-2. Epub 2022 Oct 5. PMID: 36198912; PMCID: PMC9533263.

 

Stafki SA, Turner J, Littel HR, Bruels CC, Truong D, Knirsch U, Stettner GM, Graf U, Berger W, Kinali M, Jungbluth H, Pacak CA, Hughes J, Mirchi A, Derksen A, Vincent-Delorme C, Theil AF, Bernard G, Ellis D, Fassihi H, Lehmann AR, Laugel V, Mohammed S, Kang PBThe Spectrum of MORC2-Related Disorders: A Potential Link to Cockayne Syndrome. Pediatr Neurol. 2023 Apr;141:79-86. doi: 10.1016/j.pediatrneurol.2023.01.011. Epub 2023 Jan 24. PMID: 36791574; PMCID: PMC10098370.

 

Taylor SS, Herberg FW, Veglia G, Wu J. Edmond Fischer's kinase legacy: History of the protein kinase inhibitor and protein kinase A. IUBMB Life. 2023 Apr;75(4):311-323. doi: 10.1002/iub.2714. Epub 2023 Feb 28. PMID: 36855225; PMCID: PMC10050139.

 

McFaline-Figueroa J, Hunda ET, Heo J, Winders EA, Greising SM, Call JA. The bioenergetic "CK Clamp" technique detects substrate-specific changes in mitochondrial respiration and membrane potential during early VML injury pathology. Front Physiol. 2023 Apr 4;14:1178213. doi: 10.3389/fphys.2023.1178213. PMID: 37082244; PMCID: PMC10112539.

 

Noureddine S, Nie J, Schneider A, Menon V, Fliesen Z, Dhahbi J, Victoria B, Oyer J, Robles-Carrillo L, Nunes ADC, Ashiqueali S, Janusz A, Copik A, Robbins PD, Musi N, Masternak MM. microRNA-449a reduces growth hormone-stimulated senescent cell burden through PI3K-mTOR signaling. Proc Natl Acad Sci U S A. 2023 Apr 4;120(14):e2213207120. doi: 10.1073/pnas.2213207120. Epub 2023 Mar 28. PMID: 36976763; PMCID: PMC10083567.

 

White JM, Garza A, Griebler JJ, Bates FS, Calabrese MA. Engineering the Structure and Rheological Properties of P407 Hydrogels via Reverse Poloxamer Addition. Langmuir. 2023 Apr 11;39(14):5084-5094. doi: 10.1021/acs.langmuir.3c00088. Epub 2023 Mar 27. PMID: 36971824; PMCID: PMC10593112.

 

Baik J, Ortiz-Cordero C, Magli A, Azzag K, Crist SB, Yamashita A, Kiley J, Selvaraj S, Mondragon-Gonzalez R, Perrin E, Maufort JP, Janecek JL, Lee RM, Stone LH, Rangarajan P, Ramachandran S, Graham ML, Perlingeiro RCREstablishment of Skeletal Myogenic Progenitors from Non-Human Primate Induced Pluripotent Stem Cells. Cells. 2023 Apr 13;12(8):1147. doi: 10.3390/cells12081147. PMID: 37190056; PMCID: PMC10137227.

 

Farr JN, Saul D, Doolittle ML, Kaur J, Rowsey JL, Vos SJ, Froemming MN, Lagnado AB, Zhu Y, Weivoda M, Ikeno Y, Pignolo RJ, Niedernhofer LJ, Robbins PD, Jurk D, Passos JF, LeBrasseur NK, Tchkonia T, Kirkland JL, Monroe DG, Khosla S. Local senolysis in aged mice only partially replicates the benefits of systemic senolysis. J Clin Invest. 2023 Apr 17;133(8):e162519. doi: 10.1172/JCI162519. PMID: 36809340; PMCID: PMC10104901.

 

Razzoli M, Nyuyki-Dufe K, Chen BH, Bartolomucci AContextual modifiers of healthspan, lifespan, and epigenome in mice under chronic social stress. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2211755120. doi: 10.1073/pnas.2211755120. Epub 2023 Apr 12. PMID: 37043532; PMCID: PMC10120026.

 

Silwal P, Nguyen-Thai AM, Mohammad HA, Wang Y, Robbins PD, Lee JY, Vo NV. Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities. Biomolecules. 2023 Apr 18;13(4):686. doi: 10.3390/biom13040686. PMID: 37189433; PMCID: PMC10135543.

 

Pawlak MR, Smiley AT, Ramirez MP, Kelly MD, Shamsan GA, Anderson SM, Smeester BA, Largaespada DA, Odde DJ, Gordon WRRAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes. Nat Commun. 2023 Apr 28;14(1):2468. doi: 10.1038/s41467-023-38157-6. PMID: 37117218; PMCID: PMC10147940.

March 2023

Bianchini F, Cangemi S, DeVos A, Bielecki M, Aurigemma C, Romagnoli E, Trani C, Iaizzo PA, Burzotta F. Multimodal Comparisons of Results Achieved by Different Side Branch Ballooning Techniques for Bifurcation Provisional Stenting. Circ Cardiovasc Interv. 2023 Mar;16(3):e012908. doi: 10.1161/CIRCINTERVENTIONS.123.012908. Epub 2023 Feb 27. PMID: 36943931.

 

Guhathakurta P, Rebbeck RT, Denha SA, Keller AR, Carter AL, Atang AE, Svensson B, Thomas DD, Hays TS, Avery AW. Early-phase drug discovery of β-III-spectrin actin-binding modulators for treatment of spinocerebellar ataxia type 5. J Biol Chem. 2023 Mar;299(3):102956. doi: 10.1016/j.jbc.2023.102956. Epub 2023 Jan 31. PMID: 36731793; PMCID: PMC9978034.

 

Koch RL, Soler-Alfonso C, Kiely BT, Asai A, Smith AL, Bali DS, Kang PB, Landstrom AP, Akman HO, Burrow TA, Orthmann-Murphy JL, Goldman DS, Pendyal S, El-Gharbawy AH, Austin SL, Case LE, Schiffmann R, Hirano M, Kishnani PS. Diagnosis and management of glycogen storage disease type IV, including adult polyglucosan body disease: A clinical practice resource. Mol Genet Metab. 2023 Mar;138(3):107525. doi: 10.1016/j.ymgme.2023.107525. Epub 2023 Jan 25. PMID: 36796138.

 

Le G, Baumann CW, Warren GL, Lowe DAIn vivo potentiation of muscle torque is enhanced in female mice through estradiol-estrogen receptor signaling. J Appl Physiol (1985). 2023 Mar 1;134(3):722-730. doi: 10.1152/japplphysiol.00731.2022. Epub 2023 Feb 3. PMID: 36735234; PMCID: PMC10027088.

 

Ranjbartehrani P, Ramirez DA, Schmidlin F, Etheridge M, Iaizzo PA, Shao Q, Bischof JC. Nerve Protection During Prostate Cryosurgery. Ann Biomed Eng. 2023 Mar;51(3):538-549. doi: 10.1007/s10439-022-03059-z. Epub 2022 Sep 10. PMID: 36088432.

 

Shaaban A, Schultz J, Leonard J, Martin CM, Kamdar F, Alexy T, Thenappan T, Pritzker M, Shaffer A, John R, Cogswell R. Outcomes of Patients Referred for Cardiac Rehabilitation After Left Ventricular Assist Device Implantationhttps://doi.org/10.1097/mat.0000000000001799. ASAIO J. 2023 Mar 1;69(3):304-308. doi: 10.1097/MAT.0000000000001799. Epub 2022 Aug 2. PMID: 35920751.

 

Valenzuela TF, Schinstock E, Kohnle S, Latib A, Bliagos D, Tunev S, Iaizzo PAPreclinical research performed on reanimated/perfused swine kidneys: The Visible Kidney™ methodologies. Physiol Rep. 2023 Mar;11(5):e15630. doi: 10.14814/phy2.15630. PMID: 36878878; PMCID: PMC9988650.

 

Zhang L, Pitcher LE, Prahalad V, Niedernhofer LJ, Robbins PDTargeting cellular senescence with senotherapeutics: senolytics and senomorphics. FEBS J. 2023 Mar;290(5):1362-1383. doi: 10.1111/febs.16350. Epub 2022 Feb 1. PMID: 35015337.

 

Zuckerman SL, Berven S, Streiff MB, Kerolus M, Buchanan IA, Ha A, Bonfield CM, Buchholz AL, Buchowski JM, Burch S, Devin CJ, Dimar JR, Gum JL, Good C, Kim HJ, Kim JS, Lombardi JM, Mandigo CE, Bydon M, Oppenlander ME, Polly DW Jr, Poulter G, Shah SA, Singh K, Than KD, Spyropoulos AC, Kaatz S, Jain A, Schutzer RW, Wang TZ, Mazique DC, Lenke LG, Lehman RA. Management of Anticoagulation/Antiplatelet Medication and Venous Thromboembolism Prophylaxis in Elective Spine Surgery: Concise Clinical Recommendations Based on a Modified Delphi Process. Spine (Phila Pa 1976). 2023 Mar 1;48(5):301-309. doi: 10.1097/BRS.0000000000004540. Epub 2022 Nov 14. PMID: 36730667.

 

Dahlin JL, Hua BK, Zucconi BE, Nelson SD Jr, Singh S, Carpenter AE, Shrimp JH, Lima-Fernandes E, Wawer MJ, Chung LPW, Agrawal A, O'Reilly M, Barsyte-Lovejoy D, Szewczyk M, Li F, Lak P, Cuellar M, Cole PA, Meier JL, Thomas T, Baell JB, Brown PJ, Walters MA, Clemons PA, Schreiber SL, Wagner BK. Reference compounds for characterizing cellular injury in high-content cellular morphology assays. Nat Commun. 2023 Mar 13;14(1):1364. doi: 10.1038/s41467-023-36829-x. PMID: 36914634; PMCID: PMC10011410.

 

Sellon DC, Marcellin-Little DJ, McFarlane D, McCue M, Pechette Markley A, Shoben A. Adverse health events and recommended health research priorities in agility dogs as reported by dog owners. Front Vet Sci. 2023 Mar 13;10:1127632. doi: 10.3389/fvets.2023.1127632. PMID: 36992973; PMCID: PMC10040666.

 

Ramos TL, Bolivar-Wagers S, Jin S, Thangavelu G, Simonetta F, Lin PY, Hirai T, Saha A, Koehn B, Su LL, Picton LK, Baker J, Lohmeyer JK, Riddle M, Eide C, Tolar J, Panoskaltsis-Mortari A, Wagner JE, Garcia KC, Negrin RS, Blazar BR. Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo. Blood. 2023 Mar 16;141(11):1337-1352. doi: 10.1182/blood.2022018440. PMID: 36564052; PMCID: PMC10082364.

 

Valenzuela TF 3rd, Iaizzo PAPost-procedure micro-CT analyses of coronary artery stenting in left main vessels of reanimated and perfusion-fixed human hearts. Biomed Eng Online. 2023 Mar 18;22(1):27. doi: 10.1186/s12938-023-01090-2. PMID: 36934270; PMCID: PMC10024839.

 

Vanden Noven ML, Larson M, Lee E, Reilly C, Tracy MF, Keller-Ross MLPerceptions, Benefits, and Use of Complementary and Integrative Therapies to Treat Menopausal Symptoms: A Pilot Study. Womens Health Rep (New Rochelle). 2023 Mar 27;4(1):136-147. doi: 10.1089/whr.2022.0105. Erratum in: Womens Health Rep (New Rochelle). 2023 Aug 29;4(1):463. PMID: 37008184; PMCID: PMC10061331.

 

Karthikeyan S, Asakura Y, Verma M, Asakura ATissue Clearing and Confocal Microscopic Imaging for Skeletal Muscle. Methods Mol Biol. 2023;2640:453-462. doi: 10.1007/978-1-0716-3036-5_31. PMID: 36995613.

 

Karthikeyan S, Kim K, Asakura Y, Verma M, Asakura AThree-Dimensional Imaging Analysis for Skeletal Muscle. Methods Mol Biol. 2023;2640:463-477. doi: 10.1007/978-1-0716-3036-5_32. PMID: 36995614.

 

Mondragon-Gonzalez R, Selvaraj S, Perlingeiro RCRIn Vitro Maturation of Human Pluripotent Stem Cell-Derived Myotubes. Methods Mol Biol. 2023;2640:129-142. doi: 10.1007/978-1-0716-3036-5_10. PMID: 36995592.

 

Shams AS, Kyba MThe Satellite Cell Colony Forming Cell Assay as a Tool to Measure Self-Renewal and Differentiation Potential. Methods Mol Biol. 2023;2640:45-55. doi: 10.1007/978-1-0716-3036-5_4. PMID: 36995586.

 

Xie N, Chan SSKProducing Engraftable Skeletal Myogenic Progenitors from Pluripotent Stem Cells via Teratoma Formation. Methods Mol Biol. 2023;2640:175-189. doi: 10.1007/978-1-0716-3036-5_13. PMID: 36995595.

February 2023

Arango S, Gorbaty B, Buyck D, Johnson J, Porter ST, Iaizzo PA, Perry TE. A Free-Access Online Interactive Simulator to Enhance Perioperative Transesophageal Echocardiography Training Using a High-Fidelity Human Heart 3D Model. J Cardiothorac Vasc Anesth. 2023 Feb;37(2):308-313. doi: 10.1053/j.jvca.2022.10.012. Epub 2022 Oct 13. PMID: 36372718.

 

Arango S, Gorbaty B, Tomhave N, Shervheim D, Buyck D, Porter ST, Iaizzo PA, Perry TE. A High-Resolution Virtual Reality-Based Simulator to Enhance Perioperative Echocardiography Training. J Cardiothorac Vasc Anesth. 2023 Feb;37(2):299-305. doi: 10.1053/j.jvca.2022.09.004. Epub 2022 Sep 11. PMID: 36229288.

 

Bantle AE, Lau KJ, Wang Q, Malaeb S, Harindhanavudhi T, Manoogian ENC, Panda S, Mashek DG, Chow LS. Time-restricted eating did not alter insulin sensitivity or β-cell function in adults with obesity: A randomized pilot studyhttps://doi.org/10.1002/oby.23620. Obesity (Silver Spring). 2023 Feb;31 Suppl 1(Suppl 1):108-115. doi: 10.1002/oby.23620. Epub 2022 Dec 14. PMID: 36518093; PMCID: PMC9877119.

 

Darr K, McCarthy Veach P, Wurtmann E, LeRoy BEffects of genetic counselor disabilities on their professional experiences: A qualitative investigation of North American counselors' perceptions. J Genet Couns. 2023 Feb;32(1):235-249. doi: 10.1002/jgc4.1637. Epub 2022 Sep 19. PMID: 36123146; PMCID: PMC10087727.

 

Maguina M, Kang PB, Tsai AC, Pacak CAPeripheral neuropathies associated with DNA repair disorders. Muscle Nerve. 2023 Feb;67(2):101-110. doi: 10.1002/mus.27721. Epub 2022 Oct 3. PMID: 36190439; PMCID: PMC10075233.

 

Ramirez MP, Rajaganapathy S, Hagerty AR, Hua C, Baxter GC, Vavra J, Gordon WR, Muretta JM, Salapaka MV, Ervasti JMPhosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin. J Biol Chem. 2023 Feb;299(2):102847. doi: 10.1016/j.jbc.2022.102847. Epub 2022 Dec 29. PMID: 36587764; PMCID: PMC9922815.

 

Raymond-Pope CJ, Basten AM, Bruzina AS, McFaline-Figueroa J, Lillquist TJ, Call JA, Greising SMRestricted physical activity after volumetric muscle loss alters whole-body and local muscle metabolism. J Physiol. 2023 Feb;601(4):743-761. doi: 10.1113/JP283959. Epub 2023 Jan 3. PMID: 36536512; PMCID: PMC9931639.

 

Henry TD, Yannopoulos D, van Diepen S. Extracorporeal Membrane Oxygenation for Cardiogenic Shock: When to Open the Parachute? Circulation. 2023 Feb 7;147(6):465-468. doi: 10.1161/CIRCULATIONAHA.122.063190. Epub 2023 Feb 6. PMID: 36745696.

 

McKenna DH, Perlingeiro RCRDevelopment of allogeneic iPS cell-based therapy: from bench to bedside. EMBO Mol Med. 2023 Feb 8;15(2):e15315. doi: 10.15252/emmm.202115315. Epub 2022 Dec 7. PMID: 36479608; PMCID: PMC9906386.

 

Faber EB, Wang N, John K, Sun L, Wong HL, Burban D, Francis R, Tian D, Hong KH, Yang A, Wang L, Elsaid M, Khalid H, Levinson NM, Schönbrunn E, Hawkinson JE, Georg GIScreening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. J Med Chem. 2023 Feb 9;66(3):1928-1940. doi: 10.1021/acs.jmedchem.2c01731. Epub 2023 Jan 26. PMID: 36701569.

 

Sims MB, Goetze JW, Gorbea GD, Gdowski ZM, Lodge TP, Bates FSPhotocrosslinkable Polymeric Bicontinuous Microemulsions. ACS Appl Mater Interfaces. 2023 Feb 12. doi: 10.1021/acsami.2c22927. Epub ahead of print. PMID: 36774627.

 

Coffin SL, Durham MA, Nitschke L, Xhako E, Brown AM, Revelli JP, Villavicencio Gonzalez E, Lin T, Handler HP, Dai Y, Trostle AJ, Wan YW, Liu Z, Sillitoe RV, Orr HT, Zoghbi HY. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron. 2023 Feb 15;111(4):481-492.e8. doi: 10.1016/j.neuron.2022.11.016. Epub 2022 Dec 27. Erratum in: Neuron. 2023 Mar 15;111(6):915. PMID: 36577402; PMCID: PMC9957872.

 

Handler HP, Duvick L, Mitchell JS, Cvetanovic M, Reighard M, Soles A, Mather KB, Rainwater O, Serres S, Nichols-Meade T, Coffin SL, You Y, Ruis BL, O'Callaghan B, Henzler C, Zoghbi HY, Orr HTDecreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles. Neuron. 2023 Feb 15;111(4):493-507.e6. doi: 10.1016/j.neuron.2022.11.017. Epub 2022 Dec 27. PMID: 36577403; PMCID: PMC9957934.

 

Singh BN, Yucel D, Garay BI, Tolkacheva EG, Kyba M, Perlingeiro RCR, van Berlo JH, Ogle BM. Proliferation and Maturation: Janus and the Art of Cardiac Tissue Engineering. Circ Res. 2023 Feb 17;132(4):519-540. doi: 10.1161/CIRCRESAHA.122.321770. Epub 2023 Feb 16. PMID: 36795845; PMCID: PMC9943541.

 

Rustad MD, Roopnarine O, Cornea RL, Thomas DDInteraction of DWORF with SERCA and PLB as determined by EPR spectroscopy. Biochem Biophys Res Commun. 2023 Feb 19;645:97-102. doi: 10.1016/j.bbrc.2023.01.041. Epub 2023 Jan 14. PMID: 36682333; PMCID: PMC9951557.

 

Sahu BS, Nguyen ME, Rodriguez P, Pallais JP, Ghosh V, Razzoli M, Sham YY, Salton SR, Bartolomucci A. Correction: The molecular identity of the TLQP-21 peptide receptor. Cell Mol Life Sci. 2023 Feb 20;80(3):66. doi: 10.1007/s00018-023-04718-7. Erratum for: Cell Mol Life Sci. 2021 Dec;78(23):7133-7144. PMID: 36806028; PMCID: PMC9941224.

 

Thapa S, Elhadidy S, Asakura AVascular therapy for Duchenne muscular dystrophy (DMD). Fac Rev. 2023 Feb 21;12:3. doi: 10.12703/r/12-3. PMID: 36873982; PMCID: PMC9979239.

 

Das S, Gupta V, Bjorge J, Shi X, Gong W, Garry MG, Garry DJETV2 and VEZF1 interaction and regulation of the hematoendothelial lineage during embryogenesis. Front Cell Dev Biol. 2023 Feb 27;11:1109648. doi: 10.3389/fcell.2023.1109648. PMID: 36923254; PMCID: PMC10009235.

 

Smiley AT, Tompkins KJ, Pawlak MR, Krueger AJ, Evans RL 3rd, Shi K, Aihara H, Gordon WRWatson-Crick Base-Pairing Requirements for ssDNA Recognition and Processing in Replication-Initiating HUH Endonucleases. mBio. 2023 Feb 28;14(1):e0258722. doi: 10.1128/mbio.02587-22. Epub 2022 Dec 21. PMID: 36541758; PMCID: PMC9973303.

January 2023

Abdel-Karim TR, Hodges JS, Pruett TL, Ramanathan KV, Hering BJ, Dunn TB, Kirchner VA, Beilman GJ, Bellin MD. A randomized controlled pilot trial of etanercept and alpha-1 antitrypsin to improve autologous islet engraftment. Pancreatology. 2023 Jan;23(1):57-64. doi: 10.1016/j.pan.2022.11.006. Epub 2022 Nov 24. PMID: 36443174; PMCID: PMC9839597.

 

Basten AM, Raymond-Pope CJ, Hoffman DB, Call JA, Greising SMEarly initiation of electrical stimulation paired with range of motion after a volumetric muscle loss injury does not benefit muscle function. Exp Physiol. 2023 Jan;108(1):76-89. doi: 10.1113/EP090630. Epub 2022 Sep 30. PMID: 36116106; PMCID: PMC9805496.

 

Evans CH, Ghivizzani SC, Robbins PDOsteoarthritis gene therapy in 2022. Curr Opin Rheumatol. 2023 Jan 1;35(1):37-43. doi: 10.1097/BOR.0000000000000918. Epub 2022 Nov 9. PMID: 36508307; PMCID: PMC9757842.

 

Garry DJ, Weiner JI, Greising SM, Sachs DH, Garry MGXenotransplantation and exotransplantation: Strategies to expand the number of donor organs. Xenotransplantation. 2023 Jan;30(1):e12786. doi: 10.1111/xen.12786. Epub 2022 Nov 11. PMID: 36367201.

 

Jedeon Z, Masotti M, Schultz J, Vest AR, Alexy T, Pritzker M, Maharaj V, Kamdar F, Knopper R, Shaffer A, John R, Cogswell R. Overestimation of Renal Function Using Serum Creatinine in the Advanced Heart Failure Population: A Call for Alternative Measures. J Card Fail. 2023 Jan;29(1):116-118. doi: 10.1016/j.cardfail.2022.10.428. Epub 2022 Nov 3. PMID: 36336141.

 

Ladd B, Jones K, Polly D JrRescue Pelvic Fixation in a Patient with Sacral-2-Alar-Iliac and Triangular Sacroiliac Joint Fusion (Bedrock) Instrumentation. World Neurosurg. 2023 Jan;169:10-11. doi: 10.1016/j.wneu.2022.10.045. Epub 2022 Oct 19. PMID: 36270593.

 

Tomaz da Silva M, Santos AR, Koike TE, Nascimento TL, Rozanski A, Bosnakovski D, Pereira LV, Kumar A, Kyba M, Miyabara EH. The fibrotic niche impairs satellite cell function and muscle regeneration in mouse models of Marfan syndrome. Acta Physiol (Oxf). 2023 Jan;237(1):e13889. doi: 10.1111/apha.13889. Epub 2022 Oct 17. PMID: 36164969.

 

Young MC, Vunnam N, Rebbeck RT, Yuen SL, Thomas DD, Sachs JN. Indirubin Inhibits TRAIL-Induced Activation of Death Receptor 5 in Jurkat Cells. Nat Prod Commun. 2023 Jan;18(1):10.1177/1934578x221144580. doi: 10.1177/1934578x221144580. Epub 2023 Jan 11. PMID: 37063699; PMCID: PMC10100512.

 

Allen JASARS-CoV-2 Vaccination and Autoimmune Neuropathies: Rebalancing the Risk. Neurology. 2023 Jan 10;100(2):55-56. doi: 10.1212/WNL.0000000000201366. Epub 2022 Sep 20. PMID: 36127140.

 

Nikolaienko R, Bovo E, Yuen SL, Treinen LM, Berg K, Aldrich CC, Thomas DD, Cornea RL, Zima AV. New N-aryl-N-alkyl-thiophene-2-carboxamide compound enhances intracellular Ca2+ dynamics by increasing SERCA2a Ca2+ pumping. Biophys J. 2023 Jan 17;122(2):386-396. doi: 10.1016/j.bpj.2022.12.002. Epub 2022 Dec 5. PMID: 36463408; PMCID: PMC9892616.

 

Ernst P, Bidwell PA, Dora M, Thomas DD, Kamdar FCardiac calcium regulation in human induced pluripotent stem cell cardiomyocytes: Implications for disease modeling and maturation. Front Cell Dev Biol. 2023 Jan 18;10:986107. doi: 10.3389/fcell.2022.986107. PMID: 36742199; PMCID: PMC9889838.

 

Xie N, Chu SN, Schultz CB, Chan SSKEfficient Muscle Regeneration by Human PSC-Derived CD82+ ERBB3+ NGFR+ Skeletal Myogenic Progenitors. Cells. 2023 Jan 18;12(3):362. doi: 10.3390/cells12030362. PMID: 36766703; PMCID: PMC9913306.

 

Kivimäki M, Bartolomucci A, Kawachi I. The multiple roles of life stress in metabolic disorders. Nat Rev Endocrinol. 2023 Jan;19(1):10-27. doi: 10.1038/s41574-022-00746-8. Epub 2022 Oct 12. PMID: 36224493.

 

Choma EA, Treat-Jacobson DJ, Keller-Ross ML, Wolfson J, Martin L, McMahon SK. Using the RE-AIM framework to evaluate physical activity-based fall prevention interventions in older adults with chronic conditions: A systematic review. Transl Behav Med. 2023 Jan 20;13(1):42-52. doi: 10.1093/tbm/ibac072. PMID: 36394349.