Publications

Original Articles

284. Arango S, Diaz-Gomez JL, Iaizzo P, Perry TE, Gorbaty B: A high-fidelity three-dimensional computational model of a patient with hypertrophic cardiomyopathy. CASE, Cardiovascular Imaging Case Reports, 2022. DOI: 10.1016/j.case.2022.06.005.

283. Prisco A, Hayase J, Olson MD, Brigham RC, Iaizzo PA, Shivkumar K, Bradfield J, Tholakanahalli VN: PO-671-04 Rate of change of initial intrinsicoid deflection predicts site of origin of endocardial versus epicardial ventricular tachycardia. Heart Rhythm, 19:S325, 2022. DOI: 10.1016/j.hrthm.2022.03.417.

282. Aminu AJ, Chen W, Yin Z, Kuniewicz M, Walocha J, Perde F, Molenaar P, Iaizzo PA, Dobrzynski H, Atkinson A: Novel micro-computed tomography contrast agents to visualise the human cardiac conduction system and surrounding structures in hearts from normal, aged, and obese individuals. Translational Research in Anatomy, 27:2022. DOI: 10.1016/j.tria.2022.100175.

281. Zhingre Sanchez JD, Iaizzo PA: Computationally assessed 3D anatomical proximities and spatial relationships among the tricuspid valve annulus, right coronary artery, and triangle of koch: implications for transcatheter tricuspid annuloplasty repair. Structural Heart 6:100033, 2022. DOI: 10.1016/j.shj.2022.100033.

280.Valenzuela TF, Iaizzo PA: Post-procedure Micro-CT analyses of coronary artery stenting in left main vessels of human hearts. Research Square, 2022. DOI: 10.21203/rs.3.rs-1335882/v1.

279.González-Martin P, Sacco F, Butakoff C, Doste R, Bederián C, Gutierrez Espinosa de los Monteros L, Houzeaux G, Iaizzo PA, Iles TL, Vázquez M, Aguado-Sierra J: Ventricular anatomical complexity and gender differences impact predictions from computational models. medRxiv, 2022 DOI: 10.1101/2022.01.28.22269815.

278. Upchurch WJ, Iaizzo PA: In vitro contractile studies within isolated tissue baths: Translational research from Visible Heart® Laboratories. Experimental Biology and Medicine, 2022. DOI: 10.1177/15353702211070535.

277. Holm MA, Emfield K, Iles TL, Iaizzo PA: High-resolution 3D reconstructions of human vasculatures: creation of educational tools and benchtop models for transcatheter devices. Cardiovascular Intervention and Therapeutics, 2021. DOI: 10.1007/s12928-021-00804-4.

276. Laske TG, Garshelis DL, Iles TL, Iaizzo PA: An engineering perspective on the development and evolution of implantable cardiac monitors in free-living animals. Philosophical Transactions of the Royal Society B, Biological Sciences 2;376(1830), 2021. DOI: 10.1098/rstb.2020.0217.

275. Liu H, Soares JS, Walmsley J, Li DS, Raut S, Avazmohammadi R, Iaizzo PA, Palmer M, Gorman JH 3rd, Gorman RC, Sacks MS: The impact of myocardial compressibility on organ-level simulations of the normal and infarcted heart. Scientific Reports 11:13466, 2021. DOI: 10.1038/s41598-021-92810-y.

274. Wu W, Khan B, Sharzehee M, Zhao S, Samant S, Watanabe Y, Murasato Y, Mickley T, Bicek A, Bliss R, Valenzuela T, Iaizzo PA, Makadia J, Panagopoulos A, Burzotta F, Samady H, Brilakis E, Dangas G, Louvard Y, Stankovic G, Dubini G, Migliavacca F, Kassab G, Edelman E, Chiastra C, Chatzizisis Y: Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinicial feasibility. Scientific Reports 11(1):12252, 2021. DOI: 10.1038/s41598-021-91458-y.

273. Gao Z, Baterdene N, Zonghu H, Joshi P, Rao JS, Ravikumar V, Anirudh S, Ring HL, Idiyatullin D, Magnuson EC, Iaizzo PA, Tolkacheva EG, Garwood M, Rabin Y, Etheridge M, Finger EK, Bischof JC: Vitrification and rewarming of magnetic nanoparticle-loaded rat hearts. Advanced Materials Technologies, 2021. DOI: 10.1002/admt.202100873.

272. Valenzuela TF, Burzotta F, Iles TL, Lassen JF, Iaizzo PA: Assessment of single and double coronary bifurcation stenting techniques using multimodal imaging and 3D modeling in reanimated swine hearts using Visible Heart® methodologies. International Journal of Cardiovascular Imaging 2021. DOI: 10.1007/s10554-021-02240-0.

271. Sanchez JZ, Burzotta F, Valenzuela T, Lassen JF, Iles TL, Iaizzo PA: Direct visualization of TAVR-related coronary artery management techniques in reanimated beating hearts. JACC Cardiovascular Interventions 14:e87-91, 2021. DOI: 10.1016/j.jcin.2021.02.045.

270. Prisco AR, Aguado-Sierra J, Butakoff C, Vazquez M, Houzeaux G, Eguzkitza B, Bartos JA, Yannopoulos D, Raveendran G, Holm M, Iles T, Mahr C, Iaizzo PA: Concomitant respiratory failure can impair myocardial oxygenation in patients with acute cardiogenic shock supported by VA-ECMO. Journal of Cardiovascular Translational Research 23:1-10, 2021. DOI: 10.1007/s12265-021-10110-2.

269. Haghiastiani G, Qiu K, Zhingre Sanchez JD, Fuenning ZJ, Nair P, Ahlberg SE, Iaizzo PA, McAlpine MC: 3D printed patient-specific aortic root models with internal sensors for minimally invasive applications. Science Advances 6:eabb4641, 2020. DOI: 10.1126/sciadv.abb4641.

268. Gonzalez A, Iles TL, Iaizzo PA, Bandschapp O: Impact of statin intake on malignant hyperthermia: an in vitro and in vivo swine study. BMC Anesthesiology 20:270, 2020. DOI: 10.1186/s12871-020-01186-5.

267. Holm MA, Vatterott PJ, Eggen MD, Iaizzo PA: Multimodal imaging employed during extraction of pacing or defibrillator leads from perfusion-fixed human hearts. Heart Rhythm Case Reports 6:918-921. DOI: 10.1016/j.hrcr.2020.08.025. eCollection 2020 Dec.

266. Goloviznina NA, Xie N, Dandapat A, Iaizzo PA, Kyba M: Prospective isolation of human fibroadipogenic progenitors with CD 73. Heliyon 6:e04503, 2020. DOI: 10.1016/j.heliyon.2020.e04503.

265. Tatman LM, Upchurch WJ, Scholz N, Wagstrom E, Casnovsky L, Bechtold JE, Schmidt AH, Iaizzo PA: Compartment syndrome: evaluation of skeletal muscle ischemia and physiologic biomarkers in controlled conditions within ex vivo isolated muscle bundles. Journal of Orthopaedic Trauma 34:518-523, 2020. DOI: 10.1097/BOT.0000000000001799.

264. Azzag K, Ortiz-Cordero C, Oliveira NAJ, Magli A, Selvaraj S, Tungtur S, Upchurch W, Iaizzo PA, Lu QL, Perlingeiro RCR: Efficient engraftment of pluripotent stem cell-derived myogenic progenitors in a novel immunodeficient mouse model of limb girdle muscular dystrophy. Skeletal Muscle 22:10, 2020. DOI: 10.1186/s13395-020-00228-3.

263. Zhingre Sanchez JD, Iles TL, Dvir D, Iaizzo PA: Direct visualisation of the BASILICA technique post-TAVR to enhance coronary flow. EuroIntervention 16:680-681, 2020. DOI: 10.4244/EIJ-D-20-00158.

262. Spratt JR, Mattison LM, Kerns NK, Huddleston SJ, Meyer L, Iles TL, Loor G, Iaizzo PA: Prolonged extracorporeal preservation and evaluation of human lungs with portable normothermic ex vivo perfusion. Clinical Transplantation 34:e13801, 2020. DOI: 10.1111/ctr.13801.

261. Reiff C, Zhingre Sanchez JD, Mattison LM, Iaizzo PA, Garcia S, Raveendran G, Gurevich S: 3-Dimensional printing to predict paravalvular regurgitation after transcatheter aortic valve replacement. Catheterization and Cardiovascular Interventions [Epub ahead of print, 2020]. DOI: 10.1002/ccd.28783.

260. Iles TL, Burzotta F, Lassen JF, Iaizzo PA: Stepwise visualisation of a provisional bifucation stenting procedure: multimodal visualization with a reanimated human heart utilizing Visible Heart® methodologies. Eurointervention 16:e734-737, 2020. DOI: 10.4244/EIJ-D-19-00606.

259. Bateman MG, Iles TL, Quallich SG, Shaffer AW, Iaizzo PA: Multimodal functional and still imaging of a transplanted human heart reanimated using Visible Heart® methodologies. Journal of Cardiac Surgery 35:668-671, 2020. DOI: 10.1111/jocs.14403.

258. Holm MA, Vatterott PJ, Gaasedelen EN, Syed I, Khan A, Iles TL, Iaizzo PA: Algorithm for the analysis of pre-extraction computed tomographic images to evaluate implanted lead-lead interactions and lead-vascular attachments. Heart Rhythm 17:1009-1016, 2020. DOI: 10.1016/j.hrthm.2020.01.003.

257. Deakyne AJ, Iles TL, Mattson AR, Iaizzo PA: Virtual prototyping: computational device placements within detailed human heart models. Applied Sciences 10:175, 2020. DOI: 10.3390/app10010175.

256. Iles TL, Holm MA, Calvin AD, Moller JH, Iaizzo PA: First successful open-heart surgery utilizing cross-circulation in 1954. Annals of Thoracic Surgery 110:336-341, 2020. DOI: 10.1016/j.athoracsur.2019.11.034.

255. Gaasedelen E, Deakyne A, Iaizzo PA: Automated multiclass cardiac volume segmentation and model generation. Electrical Engineering and Systems Science. September 2019. arXiv: 1909.06685.

254. Juhnke B, Mattson AR, Saltzman D, Azakie A, Hoggard E, Ambrose M, Iaizzo PA, Erdman A, Fischer G: Use of virtual reality for pre-surgical planning in separation of conjoined twins: a case report. Proceedings of the Institution of Mechanical Engineers, Part H, Journal of Engineering in Medicine 233:1327-1332, 2019. DOI: 10.1177/0954411919878067.

253. Zhingre Sanchez JD, Bateman MG, Iaizzo PA: Multimodal imaging of a self-expanding transcatheter aortic valve replacement (TAVR) procedure in a reanimated human heart and post-implant analyses. The International Journal of Cardiovascular Imaging 35:2135-2137, 2019. DOI: 10.1007/s10554-019-01645-2.

252. Howard BT, Iaizzo PA: Induced functional modulations of isolated large mammalian hearts. Pflügers Archiv 471:1095-1101, 2019. DOI: 10.1007/s00424-019-02277-0.

251. Seewald MS, Gaasedelen EN, Iles TL, Mattison LM, Mattson AR, Schmidt MM, Braun-Dullaeus RC, Iaizzo PA: Effects of ATP administration on isolated swine hearts: implications for ex vivo perfusion and cardiac transplantation. Experimental Biology & Medicine 244:915-922, 2019. DOI: 10.1177/1535370219850786.

250. Barbato E, Lara-Pezzi E, Stolen C, Taylor A, Barton PJ, Bartunek J, Iaizzo P, Judge DP, Kirshenbaum L, Blaxall BC, Terzic A, Hall JL: Advances in induced pluripotent stem cells, genomics, biomarkers, and antiplatelet therapy highlights of the year in JCTR 2013. Journal of Cardiovascular Translational Research 7:518-525, 2014. DOI: 10.1007/s12265-014-9555-7.

249. Schmidt M, Benscoter MA, Iaizzo PA: Contact forces required to record monophasic action potentials: a complement to catheter contact force measurement. IEEE Transactions on Biomedical Engineering 66:2974-2978, 2019]. DOI: 10.1109/TBME.2019.2899554.

248. Holda MK, Zhingre Sanchez JD, Bateman MG, Iaizzo PA: Right atrioventricular valve leaflet morphology redefined: implications for transcatheter repair procedures. JACC Cardiovascular Interventions 12:169-178, 2019. DOI: 10.1016/j.jcin.2018.09.029.

247. Ditmer MA, Werden LK, Tanner JC, Vincent JB, Callahan P, Iaizzo PA, Laske TG, Garshelis DL: Bears habituate to the repeated exposure of a novel stimulus, unmanned aircraft systems. Conservation Physiology 7:coy067, eCollection 2019. DOI: 10.1093.conphys/coy067.

246. Mattson AR, Yang Z, Iaizzo PA: Direct endoscopic visualization of physiologic His-bundle pacing and surrounding anatomy within reanimated human hearts employing visible heart methodologies. Heart Rhythm Case Reports 5:209-212, 2019. DOI: 10.1016.j.hrcr.2019.01.001.

245. Bateman MG, Durfee WK, Iles TL, Martin CM, Liao K, Erdman AG, Iaizzo PA: Cardiac patient-specific three-dimensional models as surgical planning tools. Surgery 167:259-263, 2020. DOI: 10.1016/j.surg.2018.11.022.

244. Sacco F, Paun B. Lehmkuhl O, Iles TL, Iaizzo PA, Houzeaux G, Vázquez M, Butakoff C, Aguado-Sierra J: Evaluating the roles of detailed endocardial structures on right ventricular haemodynamics by means of CFD simulations. International Journal for Numerical Methods in Biomedical Engineering 34:e3115, 2018. DOI: 10.1002/cnm.3115.

243. Spratt JR, Mattison LM, Iaizzo PA, Meyer C, Brown RZ, Iles T, Panoskaltsis-Mortari A, Loor G: Lung transplant after prolonged ex vivo lung perfusion: predictors of allograft function in swine. Transplant International 31:1405-1417, 2018. DOI: 10.1111/tri.13315.

242. Iles TL, Quallich SG, Iaizzo PA: Identification of radiofrequency ablation catheter parameters that may induce intracardiac steam pops: direct visualization of elicitation in reanimated swine hearts. Journal of Cardiovascular Translational Research 12:250-256, 2019. DOI: 10.1007/s12265-018-9844-7.

241. Mattson AR, Zhingre Sanchez JD, Iaizzo PA: The fixation tines of the Micra™ leadless pacemaker are atraumatic to the tricuspid valve. Pacing and Clinical Electrophysiology 41:1606-1610, 2018. DOI: 10.1111/pace.13529.

240. Laske TG, Evans AL, Arnemo JM, Iles TL, Ditmer MA, Fröbert O, Garshelis DL, Iaizzo PA: Development and utilization of implantable cardiac monitors in free-ranging American black and Eurasian brown bears: system evolution and lessons learned. Animal Biotelemetry. 6:13, 2018. DOI: 10.1186/s40317-018-0157-z.

239. Mattson AR, Mattson E, Mesich ML, Yang Z, Iaizzo PA: Electrical parameters for physiological His-Purkinje pacing vary by implant location in an ex vivo canine model. Heart Rhythm 16:443-450, 2019. DOI: 10.1016/j.hrthm.2018.09.009.

238. Schmidt MM, Iaizzo PA: The Visible Heart® project and methodologies: novel use for studying cardiac monophasic action potentials and evaluating their underlying mechanisms. Expert Review of Medical Devices 15:467-477, 2018. DOI: 10.1080/17434440.2018.1493922.

237. Schmidt MM, Hoang T, Iaizzo PA: The ability to reproducibly record cardiac action potentials from multiple anatomic locations: endocardially and epicardially, in situ and in vitro. IEEE Transactions on Biomedical Engineering 66:159-164, 2019. DOI: 10.1109/TBME.2018.2835777.

236. Mattson AR, Soto MJ, Iaizzo PA: The quantitative assessment of epicardial fat distribution on human hearts: implications for epicardial electrophysiology. Clinical Anatomy 31:661-666, 2018. DOI: 10.1002/ca.23194.

235. Sacco F, Paun B, Lehmkuhl O, Iles TL, Iaizzo PA, Houzeaux G, Vázquez M, Butakoff C, Aguado-Sierra J: Left ventricular trabeculations decrease the wall shear stress and increase the intra-ventricular pressure drop in CFD simulations. Frontiers in Physiology 9:458, eCollection 2018. DOI: 10.3389/fphys.2018.00458.

234. Singal A, Mattison LM, Soule CL, Ballard JR, Rudie EN, Cressman ENK, Iaizzo PA: Assessment of ablative therapies in swine: response of respiratory diaphragm to varying doses. Annals of Biomedical Engineering 46:947-959, 2018. DOI: 10.1007/s10439-018-2014-x.

233. Singal A, Mattison LM, Soule CL, Iaizzo PA: Effects of ablation (radio frequency, cryo, microwave) on physiologic properties of the human vastus lateralis. IEEE Transactions on Biomedical Engineering 65:2202-2209, 2018. DOI: 10.1109/TBME.2017.2787041.

232. Holm MA, Mattison LM, Vatterott P, Iaizzo PA: Direct visualization of the removal of chronically implanted pacing leads from an unfixed human cadaver. Heart Rhythm Case Reports 4;170-172, 2018. DOI: 10.1016/j.hrcr.2017.12.003.

231. Spratt, JR, Mattison LM, Iaizzo PA, Loor G: The ABCs of autologous blood collection for ex vivo organ preservation. Journal of Thoracic Cardiovascular Surgery 155:433-435, 2018. DOI: 10.1016/j.jtcvs.2017.08.036.

230. Ditmer MA, Rettler SJ, Fieberg JR, Iaizzo PA, Laske TG, Noyce KV, Garshelis DL: American black bears perceive the risks of crossing roads. Behavioral Ecology 29:667-675, 2018. DOI:10.1093/beheco/ary020.

229. Vatterott PJ, Eggen MD, Mattson AR, Omdahl PK, Hilpisch KE, Iaizzo PA: Retrieval of a chronically implanted leadless pacemaker within an isolated heart using direct visualization. Heart Rhythm Case Reports 4:167-169, 2018. DOI: 10.1016/j.hrcr.2017.11.014.

228. Stephenson RS, Atkinson A, Kottas P, Perde F, Jafarzadeh F, Bateman M, Iaizzo PA, Zhao J, Zhang H, Anderson RH, Jarvis JC, Dobrzynski H: High resolution 3-dimensional imaging of the human cardiac conduction system from microanatomy to mathematical modeling. Scientific Reports 7:7188, 2017. DOI: 10.1038/s41598-017-07694-8.

227. Paun B, Bijnens B, Iles T, Iaizzo PA, Butakoff C: Patient independent representation of the detailed cardiac ventricular anatomy. Medical Image Analysis 35:270-287, 2017. DOI: 10.1016/j.media.2016.07.006.

226. Atkinson AJ, Kharche SR, Bateman MG, Iaizzo PA, Dobrzynski H: 3D anatomical reconstruction of human cardiac conduction system and simulation of bundle branch block after TAVI procedure. Conference Proceedings of IEEE Engineering in Medicine and Biology Society 2016:5583-5586, 2016. DOI: 10.1109/EMBC.2016.7591992.

225. Eryaman Y, Zhang P, Utecht L, Kose K, Lagore RL, DelaBarre L, Kulesa J, Eberly LE, Adriany G, Iles TL, Iaizzo PA, Vaughan JT, Ugurbil K: Investigating the physiological effects of 10.5 Tesla static field exposure on anesthetized swine. Magnetic Resonance in Medicine 79:511-514, 2018. DOI: 10.1002/mrm.26672.

224. Spratt JR, Mattison LM, Iaizzo PA, Brown RZ, Helms H, Iles TL, Howard B, Panoskaltsis-Mortari A, Loor G: An experimental study of the recovery of injured porcine lungs with prolonged normothermic cellular ex vivo lung perfusion following donation after circulatory death. Transplant International 30:932-944, 2017. DOI: 10.1111/tri.12981.

223. Schmitz A, Mattison L, Iles TL, Iaizzo PA: Novel visualization of coronary stenting techniques and subsequent 3D modeling and printing of deployed devices. European Society of Cardiology (ESC) Clinical Case Gallery. Published March 28, 2017. Link: http://learn.escardio.org/clinicalcase/EACVI/87660996-24e8-4092-82fb-4c345561a234?_ga=2.245188933.1308934638.1514967717-1974636603.1456216351.

222. Laske TG, Iaizzo PA, Garshelis DL: Six years in the life of a mother bear—the longest continuous heart rate recordings from a free-ranging mammal. Scientific Reports 7:40732, 2017. DOI: 10.1038/srep40732.

221. Goff RP, Quallich SG, Buechler RA, Bischof JC, Iaizzo PA: Determination of cryothermal injury thresholds in tissues impacted by cardiac cryoablation. Cyrobiology 75:125-133, 2017. DOI: 10.1016/j.cryobiol.2017.01.002.

220. Iles TL, Laske TG, Garshelis DL, Iaizzo PA: Blood clotting behavior is innately modulated in Ursus americanus during early and late denning relative to summer months. Journal of Experimental Biology 220 (Pt 3):455-459, 2017. DOI: 10.1242/jeb.141549.

219. Seewald M, Coles Jr JA, Sigg DC, Iaizzo PA: Featured Article: Pharmacological postconditioning with delta opioid attenuates myocardial reperfusion injury in isolated porcine hearts. Experimental Biology & Medicine 242:986-995, 2017. DOI: 10.1177/1535370216684041.

218. Loor G, Howard BT, Spratt JR, Mattison LM, Panoskaltsis-Mortari A, Brown RZ, Iles TL, Meyer CM, Helms HR, Price A, Iaizzo PA: Prolonged EVLP using OCS lung: cellular and acellular perfusates. Transplantation 101:2303-2311, 2017. DOI: 10.1097/TP.0000000000001616.

217. Iaizzo PA: The Visible Heart® project and free-access website ‘Atlas of Human Cardiac Anatomy.’ Europace 18 (Suppl 4):iv163-172, 2016. DOI: 10.1093/europace/euw359.

216. Agger P, Stephenson RS, Dobrzynski H, Atkinson A, Iaizzo PA, Anderson RH, Jarvis JC, Allan SL, Partridge JB, Zhao J, Zhang H, MacIver DH: Insights from echocardiography, magnetic resonance imaging, and microcomputed tomography relative to the mid-myocardial left ventricular echogenic zone. Echocardiography 33:1546-1556, 2016. DOI: 10.1111/echo.13324.

215. Bandschapp O, Hegge TA, Bhargava EA, Ruppen W, Iaizzo PA: Utility of a standardized, multidisciplinary rehabilitation program for chronic low back pain. JSM Pain and Management 1(1): 1001 (Open access, April 2016).

214. Singal A, Ballard JR, Rudie EN, Cressman ENK, Iaizzo PA: A review of therapeutic ablation modalities. Journal of Medical Devices 10:040801-11, 2016. DOI: 10.1115/1.4033876.

213. Goff RP, Howard BT, Quallich SG, Iles TL, Iaizzo PA: The novel in vitro reanimation of isolated human and large mammalian heart-lung blocs. BMC Physiology 16:4, 2016. DOI: 10.1186/s12899-016-0023-2.

212. Omdahl P, Eggen MD, Bonner MD, Iaizzo PA, Wika K: Right ventricular anatomy can accommodate multiple Micra transcatheter pacemakers. Pacing & Clinical Electrophysiology 39:393-397, 2016. DOI: 10.1111/pace.12804.

211. Ditmer MA, Garshelis DL, Noyce KV, Laske TG, Iaizzo PA, Burk TE, Forester JD, Fieberg JR: Behavioral and physiological responses of American black bears to landscape features within an agricultural region. Ecosphere 6:Article 28 (Open access, 2015). DOI: 10.1890/ES14-00199.1.

210. Quallich SG, Kriege KE, Iaizzo, PA: The effects of radiofrequency or cryothermal ablation on biomechanical properties of isolated human or swine cardiac tissues. IEEE Journal of Translational Engineering in Health and Medicine 4:1900105:1-5, eCollection 2016. DOI: 10.1109/JTEHM.2015.2506160.

209. Benscoter MA, Avitall B, Iaizzo PA: Visualization of an innovative approach for mitral isthmus ablation. Journal of Integrative Cardiology (Open access, 2015). DOI: 10.15761/JIC.1000139.

208. Ginz HF, Iaizzo PA, Schweikert K, Durfee WK: Isometric skeletal muscle force measurement in primary myopathies. Muscle & Nerve 53:913-917, 2016. DOI: 10.1002/mus.24954.

207. Benscoter MA, Iaizzo PA: Visualization of catheter ablation for atrial fibrillation: impact of devices and anatomy. World Journal of Cardiology 7:754-764, 2015. DOI: 10.4330/wjc.v7.i11.754.

206. Benscoter MA, Iaizzo PA: Assessing the relative integrity of formed cardiac linear lesions by recording both focal and monophasic action potentials and contact forces: a technical brief. IEEE Journal of Translational Engineering in Health and Medicine 3:1900606, eCollection 2015. DOI: 10.1109/JTEHM.2015.2473856.

205. Howard SA, Goff RP, Benditt DG, Iaizzo PA: Direct visualization of an iatrogenic septal defect in a reanimated human heart. Heart Rhythm Case Reports l:509-510, eCollection 2015. DOI: 10.1016/j.hrcr.2015.08.011.

204. Ditmer MA, Vincent JB, Werden LK, Tanner, JC, Laske TG, Iaizzo PA, Garshelis DL, Fieberg JR: Bears show a physiological but limited behavioral response to unmanned aerial vehicles. Current Biology 25: 2278-2283, 2015. DOI: 10.1016/j.cub.2015.07.024.

203. Quallich SG, Goff RP, Iaizzo PA: Direct visualization of induced steam pops during radiofrequency ablation. Heart Rhythm Case Reports 1:264-265, eCollection 2015. DOI: 10.1016/j.hrcr.2015.02.012.

202. Goff RP, Spencer JH, Iaizzo PA: MRI reconstructions of human phrenic nerve anatomy and computational modeling of cryoballoon ablative therapy. Annals of Biomedical Engineering 44:1097-1106, 2016. DOI: 10.1007/s10439-015-1379-3.

201. Colbert RW, Holley CT, Stone LH, Crampton M, Adabag S, Garcia S, Iaizzo PA, Ward HB, Kelly RF, McFalls EO: The recovery of hibernating hearts lies on a spectrum: from bears in nature to patients with coronary artery disease. Journal of Cardiovascular Translational Research 8:244-252, 2015. DOI: 10.1007/s12265-015-9625-5.

200. Burzotta F, Cook B, Iaizzo PA, Singh J, Louvard Y, Latib A: Coronary bifurcations as you have never seen them: the Visible Heart® Laboratory bifurcation programme. EuroIntervention 11 (Suppl V):V40-43, 2015. DOI: 10.4244/EIJV11SVA9.

199. Spencer JH, Goff RP, Iaizzo PA: Left phrenic nerve anatomy relative to the coronary venous system: implications for phrenic nerve stimulation during cardiac resynchronization therapy. Clinical Anatomy 28:621-626, 2015. DOI: 10.1002/ca.22537.

198. Yang Z, Eggen MD, Marquardt KR, Asleson AJ, McVenes RD, Iaizzo PA: Direct visualization of an atrial transseptal left ventricular endocardial lead implantation within an isolated heart. Heart Rhythm Case Reports 1:107-109, eCollection 2015. DOI: 10.1016/j.hrcr.2015.01.001.

197. Laske TG, Garshelis DL, Iaizzo PA: Big data in wildlife research: remote web-based monitoring of hibernating black bears. BMC Physiology 14:13, 2014. DOI: 10.1186/s12899-014-0013-1.

196. Howard SA, Quallich SG, Benscoter MA, Holmgren BC, Rolfes CD, Iaizzo PA: Tissue properties of the fossa ovalis as they relate to transseptal punctures: a translational approach. Journal of Interventional Cardiology 28:98-108, 2015. DOI: 10.1111/joic.12174.

195. Quallich SG, Van Heel M, Iaizzo PA: Optimal contact forces to minimize cardiac perforations before, during, and/or after radiofrequency or cryothermal ablations. Heart Rhythm 12:291-296, 2015. DOI: 10.1016/j.hrthm.2014.11.028.

194. Iles TL, Howard B, Howard S, Quallich S, Rolfes C, Richardson E, Iaizzo HR, Iaizzo PA: Testing the efficacy of pharmacological agents in a pericardial target delivery model in the swine. Journal of Visualized Experiments 113:e52600:1-7, July 7, 2016. DOI: 10.3791/52600.

193. Goff RP, Bersie SM, Iaizzo PA: In vitro assessment of induced phrenic nerve cryothermal injury. Heart Rhythm 11:1779-1784, 2014. DOI: 10.1016/j.hrthm.2014.06.022.

192. Spencer JH, Prahl G, Iaizzo PA: The prevalence of coronary sinus and left circumflex artery overlap in relation to the mitral valve. Journal of Interventional Cardiology 27:308-316, 2014. DOI: 10.1111/joic.12106.

191. Spencer JH, Sundaram CC, Iaizzo PA: The relative anatomy of the coronary arterial and venous systems: implications for coronary interventions. Clinical Anatomy 27:1023-1029, 2014. DOI: 10.1002/ca.22419.

190. Eggen MD, Bonner MD, Williams ER, Iaizzo PA: Multimodal imaging of a transcatheter pacemaker implantation within a reanimated human heart. Heart Rhythm 11:2331-2332, 2014. DOI: 10.1016/j.hrthm.2014.03.052.

189. Spencer JH, Larson AA, Drake R, Iaizzo PA: A detailed assessment of the human coronary venous system using contrast computed tomography of perfusion-fixed specimens. Heart Rhythm 11:282-288, 2014. DOI: 10.1016/j.hrthm.2013.10.038.

188. Freiermuth D, Bandschapp O, Iaizzo PA: Heat production and the importance of temperature management in malignant hyperthermia. International Journal of Anesthesiology Research, 1:47-55, 2013. DOI: 10.14205/2310-9394.2013.01.01.6.

187. Gladen A, Iaizzo PA, Bischof JC, Erdman AG, Divani AA: A head and neck support device for inducing local hypothermia. Journal of Medical Devices 8:0110021-110029, 2014. DOI: 10.1115/1.4025448.

186. Spencer JH, Quill JL, Bateman MG, Eggen MD, Howard SA, Goff RP, Howard BT, Quallich SG, Iaizzo PA: The benefits of the Atlas of Human Cardiac Anatomy website for the design of cardiac devices. Expert Review of Medical Devices 10:729-734, 2013. DOI: 10.1586/17434440.2013.843449.

185. Bandschapp O, Iaizzo PA: Pathophysiologic and anesthetic considerations for patients with myotonia congenita or periodic paralyses. Pediatric Anesthesia 23:824-833, 2013. DOI: 10.1111/pan.12217.

184. Spencer J, Fitch E, Iaizzo PA: Anatomical reconstructions of the human cardiac venous system using contrast-computed tomography of perfusion-fixed specimens. Journal of Visualized Experiments 74:e50258:1-5, 2013. DOI: 10.3791/50258.

183. Bandschapp O, Iaizzo PA, Girard T: Malignant hyperthermia: update of diagnostics. Trends in Anaesthesia and Critical Care 2:218-223, 2012. DOI: 10.1016/j.tacc.2012.08.001.

182. Howard SA, Quill JL, Eggen MD, Swingen CM, Iaizzo PA: Novel imaging of atrial septal defects in isolated human hearts. Journal of Cardiovascular Translational Research 6:218-220, 2013. DOI: 10.1007/s12265-013-9451-6.

181. Spencer JH, Anderson SE, Iaizzo PA: Human coronary venous anatomy: implications for interventions. Journal of Cardiovascular Translational Research 6:208-217, 2013. DOI: 10.1007/s12265-012-9443-y.

180. Bateman MG, Quill JL, Hill AJ, Iaizzo PA: The clinical anatomy and pathology of the human arterial valves: implications for repair or replacement. Journal of Cardiovascular Translational Research 6:166-175, 2013. DOI: 10.1007/s12265-012-9438-8.

179. Bateman MG, Quill JL, Hill AJ, Iaizzo PA: The clinical anatomy and pathology of the human atrioventricular valves: implications for repair or replacement. Journal of Cardiovascular Translational Research 6:155-165, 2013. DOI: 10.1007/s12265-012-9437-9.

178. Iaizzo PA, Anderson RH, Hill AJ: The importance of human cardiac anatomy for translational research. Journal of Cardiovascular Translational Research 6:6:105-106, 2013. DOI: 10.1007/s12265-012-9419-y.

177. Howard SA, Bateman MG, Hill AJ, Anderson RH, Iaizzo PA: In vitro images of a double orifice mitral valve in a reanimated human heart. Annals of Thoracic Surgery 95:1456, 2013. DOI: 10.1016/j.athoracsur.2012.08.061.

176. Bateman MG, Iaizzo PA: Imaging in the context of replacement heart valve development: use of the Visible Heart® methodologies. Cardiovascular Diagnosis and Therapy 2:220-230, 2012. DOI: 10.3978/j.issn.2223-3652.2012.07.01.

175. Tsang W, Bateman MG, Weinert L, Pellegrini G, Mor-Avi V, Sugeng L, Yeung H, Patel AR, Hill AJ, Iaizzo PA, Lang RM: Accuracy of aortic annular measurements obtained from three-dimensional echocardiography, CT and MRI: human in vitro and in vivo studies. Heart 98:1146-1152, 2012. DOI: 10.1136/heartjnl-2012-302074.

174. Bandschapp O, Goff R, Mallin G, Loushin M, Iaizzo PA: The path of a pulmonary artery catheter visualized through a beating human heart. American Journal of Respiratory and Critical Care Medicine 186:385, 2012. DOI: 10.1164/rccm.201112-2227IM.

173. Liu C, Eggen MD, Swingen CM, Iaizzo PA, He B: Noninvasive mapping of transmural potentials during activation in swine hearts from body surface electrocardiograms. IEEE Transactions on Medical Imaging 31:1777-1185, 2012. DOI: 10.1109/TMI.2012.2202914.

172. Shrivastav M, Ghai MB, Singal A, Iaizzo PA: The design and use of an optical mapping system for the study of intracardiac electrical signaling. Indian Pacing and Electrophysiology Journal 12:138-151, 2012. DOI: 10.1016/s0972-6292(16)30521-6.

171. Cressman EN, Shenoi MM, Edelman TL, Geeslin MG, Hennings LJ, Zhang Y, Iaizzo PA, Bischof JC: In vivo comparison of simultaneous versus sequential injection technique for thermochemical ablation in a porcine model. International Journal of Hyperthermia 28:105-112, 2012. DOI: 10.3109/02656736.2011.644620.

170. Cressman EN, Geeslin MG, Shenoi MM, Hennings LJ, Zhang Y, Iaizzo PA, Bischof JC: Concentration and volume effects in thermochemical ablation in vivo: results in a porcine model. International Journal of Hyperthermia 28:113-121, 2012. DOI: 10.3109/02656736.2011.644621.

169. Bandschapp O, Soule CL, Iaizzo PA: Lactic acid restores skeletal muscle force in an in vitro fatigue model: are voltage-gated chloride channels involved? American Journal of Physiology-Cell Physiology 302:C1019-1025, 2012. DOI: 10.1152/ajpcell.00279.2011.

168. Faridar A, Bershad EM, Emiru T, Iaizzo PA, Suarez JI, Divani AA: Therapeutic hypothermia in stroke and traumatic brain injury. Frontiers in Neurology 2:80, eCollection 2011. DOI: 10.3389/fneur.2011.00080.

167. Bandschapp O, Sweney MT, Miller JA, Tahvildari S, Sigg DC, Iaizzo PA: Induction of mild hypothermia by noninvasive body cooling in healthy, unanesthetized subjects. Therapeutic Hypothermia and Temperature Management 1:193-198, 2011. DOI: 10.1089/ther.2011.0006.

166. Iaizzo PA, Laske TG, Harlow HJ, McClay CB, Garshelis DL: Wound healing during hibernation by black bears (Ursus americanus) in the wild: elicitation of reduced scar formation. Integrative Zoology 7:48-60, 2012. DOI: 10.1111/j.1749-4877.2011.00280.x.

165. Eggum JH, Howard SA, Goff RP, Iaizzo PA: Imaging of a coronary artery stent implantation within an isolated human heart. Journal of Cardiovascular Translational Research 5:73-74, 2012. DOI: 10.1007/s12265-011-9322-y.

164. Rolfes CD, Howard SA, Goff RP, Iaizzo PA: Cardiac remodeling as a consequence of atrial fibrillation: an anatomical study of perfusion-fixed human heart specimens. Journal of Geriatric Cardiology 8:141-146, 2011. DOI: 10.3724/SP.J.1263.2011.00141.

163. Laske TG, Garshelis DL, Iaizzo PA: Monitoring the wild black bear’s reaction to human and environmental stressors. BMC Physiology 11:13, 2011. DOI: 10.1186/1472-6793-11-13.

162. Lai D, Liu C, Eggen MD, Iaizzo PA, He B: Localization of endocardial ectopic activity by means of noninvasive endocardial surface current density reconstruction. Physics in Medicine and Biology 56:4161-4176, 2011. DOI: 10.1088/0031-9155/56/13/027.

161. Richardson ES, Rolfes C, Woo OS, Elmquist WF, Benditt DG, Iaizzo PA: Cardiac responses to the intrapericardial delivery of metoprolol: targeted delivery compared to intravenous administration. Journal of Cardiovascular Translational Research 5:535-540, 2012. DOI: 10.1007/s12265-011-9315-x.

160. Eggen MD, Swingen CM, Iaizzo PA: Ex vivo diffusion tensor MRI of human hearts: relative effects of specimen decomposition. Magnetic Resonance in Medicine 67:1703-1709, 2012. DOI: 10.1002/mrm.23194.

159. Anderson SE, Eggum JH, Iaizzo PA: Modeling of induced electric fields as a function of cardiac anatomy and venous pacing lead location. Cardiovascular Engineering and Technology 2:399-407, 2011. DOI: 10.1007/s13239-011-0057-3.

158. Liu C, Iaizzo PA, He B: Three-dimensional imaging of ventricular activation and electrograms from intracavitary recordings. IEEE Transactions on Biomedical Engineering 58:868-875, 2011. DOI: 10.1109/TBME.2010.2097598.

157. Quill JL, Hill AJ, Menk AR, McHenry BT, Iaizzo PA: Multimodal imaging of a transcatheter aortic valve implantation within an isolated heart. JACC Cardiovascular Imaging 4:1138-1139, 2011. DOI: 10.1016/j.jcmg.2011.02.025.

156. Bandschapp O, Iaizzo PA: Induction of therapeutic hypothermia requires modulation of thermoregulatory defenses. Therapeutic Hypothermia and Temperature Management 1:77-85, 2011. DOI: 10.1089/ther.2010.0010.

155. Bateman MG, Iaizzo PA: Comparative imaging of cardiac structures and function for the optimization of transcatheter approaches for valvular and structural heart disease. International Journal of Cardiovascular Imaging 27:1223-1234, 2011. DOI: 10.1007/s10554-011-9807-4.

154. Quill JL, Bateman MG, St. Louis JL, Iaizzo PA: Edge-to-edge repairs of P2 prolapsed mitral valves in isolated swine hearts. Journal of Heart Valve Disease 20:5-12, 2011. PMID: 21404891.

153. Richardson ES, Iaizzo PA, Xiao YF: Electrophysiological mechanisms of the anti-arrhythmic effects of omega-3 fatty acids. Journal of Cardiovascular Translational Research 4:42-52, 2011. DOI: 10.1007/s12265-010-9243-1.

152. Shrivastava D, Abosch A, Hanson T, Tian J, Gupte A, Iaizzo PA, Vaughan JT: Effect of the extracranial deep brain stimulation lead on radiofrequency heating at 9.4 Tesla (400.2 MHz). Journal of Magnetic Resonance Imaging 32:600-607, 2010. DOI: 10.1002/jmri.22292.

151. Lai D, Liu C, Eggen MD, Iaizzo PA, He B: Equivalent moving dipole localization of cardiac ectopic activity in a swine model during pacing. IEEE Transactions on Information Technology in Biomedicine 14:1318-1326, 2010. DOI: 10.1109/TITB.2010.2051448.

150. Venkatasubramanian RT, Wolkers WF, Shenoi MM, Barocas VH, Lafontaine D, Soule CL, Iaizzo PA, Bischof JC: Freeze-thaw induced biomechanical changes in arteries: role of collagen matrix and smooth muscle cells. Annals of Biomedical Engineering 38:694-706, 2010. DOI: 10.1007/s10439-010-9921-9.

149. Laske TG, Harlow HJ, Garshelis DL, Iaizzo PA: Extreme respiratory sinus arrhythmia enables overwintering black bear survival—physiological insights and applications to human medicine. Journal of Cardiovascular Translational Research 3:559-569, 2010. DOI: 10.1007/s12265-010-9185-7.

148. Xiao YF, Chandler N, Dobryzynski H, Richardson ES, Tenbroek EM, Wilhelm JJ, Sharma V, Varghese A, Boyett MR, Iaizzo PA, Sigg DC: Hysteresis in human HCN4 channels: a crucial feature potentially affecting sinoatrial node pacemaking. Sheng Li Zue Bao 62:1-13, 2010. PMID: 20179882.

147. Eggen MD, Bateman MG, Rolfes CD, Howard SA, Swingen CM, Iaizzo PA: MRI assessment of pacing induced ventricular dyssynchrony in an isolated human heart. Journal of Magnetic Resonance Imaging 31:466-469, 2010. DOI: 10.1002/jmri.22050.

146. Shrivastav M, Iaizzo PA: An interactive graphical user interface for comprehensive analysis of human and swine cardiac monophasic action potential. Computers in Biology and Medicine 39:1105-1116, 2009. DOI: 10.1016/j.compbiomed.2009.09.005.

145. Marshall MT, Liao KK, Loushin MK, Iaizzo PA: The effects of temperature on cardiac pacing thresholds. Pacing and Clinical Electrophysiology 33:826-833, 2010. DOI: 10.1111/j.1540-8159.2009.02681.x.

144. Anderson SE, Iaizzo PA: Effects of left ventricular lead positions and coronary venous microanatomy on cardiac pacing parameters. Journal of Electrocardiology 43:136-141, 2010. DOI: 10.1016/j.jelectrocard.2009.08.002.

143. Shrivastava D, Hanson T, Kulesa J, DelaBarre L, Iaizzo P, Vaughan JT: Radio frequency heating at 9.4T (400.2 MHz): in vivo thermoregulatory temperature response in swine. Magnetic Resonance in Medicine 62:888-895, 2009. DOI: 10.1002/mrm.22072.

142. Skadsberg ND, Kaiser DR, Fischer TM, Iaizzo PA: Global electrophysiological and hemodynamic assessment of ventricular pacing employing non-contact mapping. Journal of Interventional Cardiac Electrophysiology 26:185-194, 2009. DOI: 10.1007/s10840-009-9431-6.

141. Richardson ES, Whitson BA, Iaizzo PA: A novel combination therapy for post-operative arrhythmias. Journal of Medical Devices 3:027511, 2009. DOI: 10.1115/1.3135155.

140. Bandschapp O, Ginz HF, Soule CL, Girard T, Urwyler A, Iaizzo PA: In vitro effects of propofol and volatile agents on pharmacologically induced chloride channel myotonia. Anesthesiology 111:584-590, 2009. DOI: 10.1097/ALN.0b013e3181b05f23.

139. Whitson BA, Richardson E, Iaizzo PA, Hess DJ: Not every bulb is a rose: a functional comparison of bulb suction devices. Journal of Surgical Research 156:270-273, 2009. DOI: 10.1016/j.jss.2009.03.096.

138. Quill JL, Hill AJ, Laske TG, Alfieri O, Iaizzo PA: Mitral leaflet anatomy revisited. Journal of Thoracic and Cardiovascular Surgery 137:1077-1081, 2009. DOI: 10.1016/j.jtcvs.2008.10.008.

137. Love CJ, Ahlberg SE, Hiniduma-Lokuge P, Brabec S, Iaizzo PA: Novel visualization of intracardiac pacing lead extractions: methodologies performed within isolated canine hearts. Journal of Interventional Cardiac Electrophysiology 24:27-31, 2009. DOI: 10.1007/s10840-008-9306-2.

136. Anderson SE, Hill AJ, Iaizzo PA: Microanatomy of human left ventricular coronary veins. Anatomical Record 292:23-28, 2009. DOI: 10.1002/ar.20766.

135. Liu C, Skadsberg ND, Ahlberg SE, Swingen CM, Iaizzo PA, He B: Noninvasive estimation of three-dimensional cardiac electrical activities from body surface potential maps. Conference Proceedings of IEEE Engineering in Medicine and Biology Society 2008:4544-4547, 2008. DOI: 10.1109/IEMBS.2008.4650223.

134. Anderson SE, Quill JL, Iaizzo PA: Venous valves within left ventricular coronary veins. Journal of Interventional Cardiac Electrophysiology 23:95-99, 2008. DOI: 10.1007/s10840-008-9282-6.

133. Xiao YF, Sigg DC, Ujhelyi MR, Wilhelm JJ, Richardson ES, Iaizzo PA: Pericardial delivery of omega-3 fatty acid: a novel approach to reducing myocardial infarct sizes and arrhythmias. American Journal of Physiology: Heart and Circulatory Physiology 294:H2212-2218, 2008. DOI: 10.1152/ajpheart.91502.2007.

132. Iaizzo PA, Hill AJ, Laske TG: Cardiac device testing enhanced by simultaneous imaging modalities: the Visible Heart, fluoroscopy, and echocardiography. Expert Review of Medical Devices 5:51-58, 2008. DOI: 10.1586/17434440.5.1.51.

131. Liu C, Skadsberg ND, Ahlberg SE, Swingen CM, Iaizzo PA, He B: Estimation of global ventricular activation sequences by noninvasive three-dimensional electrical imaging: validation studies in a swine model during pacing. Journal of Cardiovascular Electrophysiology 19:535-540, 2008. DOI: 10.1111/j.1540-8167.2007.01066.x.

130. Hucker WJ, McCain ML, Laughner JI, Iaizzo PI, Efimov IR: Connexin 43 expression delineates two discrete pathways in the human atrioventricular junction. Anatomical Record 291:204-215, 2008. DOI: 10.1002/ar.20631.

129. Ahlberg SA, Yue AM, Skadsberg ND, Roberts PR, Iaizzo PA, Morgan JM: Investigation of pacing site-related changes in global restitution dynamics by non-contact mapping. Europace 10:40-45, 2008. DOI: 10.1093/europace/eum238.

128. Quill JL, Laske TG, Hill AJ, Bonhoeffer P, Iaizzo PA: Images in cardiovascular medicine. Direct visualization of a transcatheter pulmonary valve implantation within the Visible Heart–a glimpse into the future. Circulation 116:e548, 2007. DOI: 10.1161/.CIRCULATIONAHA.107.728667.

127. Kimmel MW, Skadsberg ND, Byrd CL, Wright DJ, Laske TG, Iaizzo PA: Single-site ventricular and biventricular pacing: investigation of latest depolarization strategy. Europace, 9:1163-1170, 2007. DOI: 10.1093/europace/eum218.

126. Anderson SE, Hill AJ, Iaizzo PA: Venous valves: unseen obstruction to coronary sinus. Journal of Interventional Cardiac Electrophysiology 19:165-166, 2007. DOI: 10.1007/s10840-007-9161-6.

125. Ahlberg SE, Grenz NA, Ewert DL, Iaizzo PA, Mulligan LJ: Effect of pacing site on systolic mechanical restitution curves in the in vivo canine model. Cardiovascular Engineering, 7:89-96, 2007. DOI: 10.1007/s10558-007-9033-9.

124. Ginz HF, Iaizzo PA, Urwyler A, Pargger H: Use of non-invasive-stimulated muscle force assessment in long-term critically ill patients: a future standard in the intensive care unit? Acta Anaesthesiologica Scandinavica 52:20-27, 2008. DOI: 10.1111/j.1399-6576.2007.01427.x.

123. Anderson SE, Skadsberg ND, Laske TG, Benditt DG, Iaizzo PA: Variation in pacing impedance: impact of implant site and measurement method. Pacing and Clinical Electrophysiology 30:1076-1082, 2007. DOI: 10.1111/j.1540-8159.2007.00816.x.

122. Shrivastav M, Shrivastav R, Iaizzo PA: Following the beat of cardiac potentials. IEEE Potentials 26:19-25, 2007. DOI: 10.1109/MP.2007.361640.

121. Ahlberg SE, Hamlen RC, Ewert DL, Iaizzo PA, Mulligan LJ: Novel means to monitor cardiac performance: the impact of the force-frequency and force-interval relationships on recirculation fraction and potentiation ratio. Cardiovascular Engineering 7:32-38, 2007. DOI: 10.1007/s10558-007-9023-y.

120. Lü F, Iaizzo PA, Benditt DG, Mehra R, Warman EN, McHenry BT: Isolated atrial segment pacing: an alternative to His bundle pacing after atrioventricular junctional ablation. Journal of the American College of Cardiology 49:1443-1449, 2007. DOI: 10.1016/j.jacc.2006.12.034.

119. Bischoff TC, Martens MD, Adams MH, Gallagher WJ, Iaizzo PA: Measurement of impact loads applied to an implanted drug pump connector in a porcine cadaver specimen. Journal of Medical Devices 1:119-125, 2007. DOI: 10.1115/1.2736398.

118. Shrivastav M, Iaizzo PA: In vivo cardiac monophasic action potentials recorded using electromyogram needles. IEEE Biomedical Circuits and Systems Conference, 2006. DOI: 10.1109/BIOCAS.2006.4600350.

117. Ahlberg SE, Ripplinger CM, Skadsberg ND, Iaizzo PA, Mulligan LJ: Effects of pacing rate on mechanical restitution within the in vivo canine heart: study of the force-frequency relationship. Journal of Cardiovascular Electrophysiology, 18:212-217, 2007. DOI: 10.1111/j.1540-8167.2006.00712.x.

116. Lohuis TD, Harlow HJ, Beck TD, Iaizzo PA: Hibernating bears conserve muscle strength and maintain fatigue resistance. Physiological and Biochemical Zoology 80:257-269, 2007. DOI: 10.1086/513190.

115. Snedeker JG, Barnstuble BB, Iaizzo PA, Farshad M, Niederer P, Schmidlin FR: A comprehensive renal injury concept based on a validated finite element model of the human abdomen. Journal of Trauma: Injury, Infection, and Critical Care 62:1240-1249, 2007. DOI: 10.1097/01.ta.0000215531.05677.19.

114. Chromy CA, Carey MT, Balgaard KG, Iaizzo PA: The potential use of axial spinal unloading in the treatment of adolescent idiopathic scoliosis: a case series. Archive of Physical Medicine and Rehabilitation, 87:1447-1453, 2006. DOI: 10.1016/j.apmr.2006.08.325.

113. Sigg DC, Iaizzo PA: In vivo versus in vitro comparison of swine cardiac performance: induction of cardiodepression with halothane. European Journal of Pharmacology 543:97-107, 2006. DOI: 10.1016/j.ejphar.2006.06.011.

112. Hill AJ, Ahlberg SE, Wilkoff BL, Iaizzo PA: Dynamic obstruction to coronary sinus access: the Thebesian valve. Heart Rhythm 3:1240-1241, 2006. DOI: 10.1016/j.hrthm.2006.04.013.

111. Xiao YF, TenBroek EM, Wilhelm JJ, Iaizzo PA, Sigg DC: Electrophysiological characterization of murine HL-5 atrial cardiomyocytes. American Journal of Physiology: Cell Physiology 291:C407-416, 2006. DOI: 10.1152/ajpcell.00020.2006.

110. Solá S, Garshelis DL, Amaral JD, Noyce KV, Coy PL, Steer CJ, Iaizzo PA, Rodrigues CM: Plasma levels of ursodeoxycholic acid in black bears, Ursus americanus: seasonal changes. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 143:204-208, 2006. DOI: 10.1016/j.cbpc.2006.02.002.

109. Laske TG, Skadsberg ND, Hill AJ, Klein GJ, Iaizzo PA: Excitation of the intrinsic conduction system through His and intraventricular septal pacing. Pacing and Clinical Electrophysiology 29:397-405, 2006. DOI: 10.1111/j.1540-8159.2006.00360.x.

108. Ginz HF, Iaizzo PA, Girard T, Urwyler A, Pargger H: Decreased isometric skeletal muscle force in critically ill patients. Swiss Medical Weekly 135:555-561, 2005. DOI: 2005/37/smw-11139.

107. Laske TG, Harlow HJ, Werder JC, Marshall MT, Iaizzo PA: High capacity implantable data recorders: system design and experience in canines and denning black bears. Journal of Biomechanical Engineering 127:964-971, 2005. DOI: 10.1115/1.2049340.

106. Laske TG, Skadsberg ND, Iaizzo PA: A novel ex vivo heart model for the assessment of cardiac pacing systems. Journal of Biomechanical Engineering 127:894-898, 2005. DOI: 10.1115/1.2049312.

105. Laske TG, Vieau SA, Skadsberg ND, Iaizzo PA: High pacing impedances: are you overtorquing your leads? Pacing and Clinical Electrophysiology 28:883-891, 2005. DOI: 10.1111/j.1540-8159.2005.00192.x.

104. Coles JA Jr, Sigg DC, Iaizzo PA: The potential benefits of 1.5% hetastarch as a cardioplegia additive. Biochemical Pharmacology 69:1553-1558, 2005. DOI: 10.1016/j.bcp.2005.03.010.

103. Hong J, Sigg DC, Coles JA JR, Oeltgen PR, Harlow HJ, Soule CL, Iaizzo PA: Hibernation induction trigger reduces hypoxic damage of swine skeletal muscle. Muscle & Nerve 32;200-207, 2005. DOI: 10.1002/mus.20354.

102. Hill AJ, Laske TG, Coles JA Jr, Sigg DC, Skadsberg ND, Vincent SA, Soule CL, Gallagher WJ, Iaizzo PA: In vitro studies of human hearts. Annals of Thoracic Surgery 79:168-177, 2005. DOI: 10.1016/j.athoracsur.2004.06.080.

101. Hong J, Falkenberg JH, Iaizzo PA: Stimulated muscle force assessment of the sternocleidomastoid muscle in humans. Journal of Medical Engineering & Technology 29:82-89, 2005. DOI: 10.1080/03091900412331271158.

100. Iaizzo, PA: Temperature modulation of pressure ulcer formation: using a swine model. WOUNDS: A Compendium of Clinical Research and Practice 16:336-343, 2004.

99. Ginz HF, Zorzato F, Iaizzo PA, Urwyler A: Effect of three anaesthetic techniques on isometric skeletal muscle strength. British Journal of Anaesthesia 92:367-372, 2004. DOI: 10.1093/bja/aeh080.

98. He X, McGee S, Coad JE, Schmidlin F, Iaizzo PA, Swanlund DJ, Kluge S, Rudie E, Bischof JC: Investigation of the thermal and tissue injury behaviour in microwave thermal therapy using a porcine kidney model. International Journal of Hyperthermia 20:567-593, 2004. DOI: 10.1080/0265673042000209770.

97. Hill AJ, Coles JA Jr, Sigg DC, Laske, TG, Iaizzo PA: Images of the human coronary sinus ostium obtained from isolated working hearts. Annals of Thoracic Surgery 76:2108, 2003. DOI: 10.1016/S0003-4975(03)00268-6.

96. Hilse MA, Erdman AG, Iaizzo PA: Axial unloading therapy device for cervical spine rehabilitation. Journal of Medical Engineering & Technology 27:207-217, 2003. DOI: 10.1080/0309190031000096685.

95. Coles JA Jr, Sigg, D, Iaizzo PA: Role of kappa-opioid receptor activation in pharmacological preconditioning in swine. American Journal of Physiology: Heart and Circulatory Physiology 284:H2091-2099, 2003. DOI: 10.1152/ajpheart.00843.2002.

94. Christiansen SP, Becker BA, Iaizzo PA, McLoon LK: Extraocular muscle force generation after ricin-mAb35 injection: implications for strabismus treatment. Journal of American Association for Pediatric Opthalmology and Strabismus 7:1-6, 2003. DOI: 10.1067/mpa.2003.S1091853103000569.

93. Schulte-Mattler WJ, Müller T, Deschauer M, Gellerich FN, Iaizzo PA, Zierz S: Increased metabolic muscle fatigue is caused by some but not all mitochondrial mutations. Archives of Neurology 60:50-58, 2003. DOI: 10.1001/archneur.60.1.50.

92. Lahm R, Iaizzo PA: Physiologic responses during rest on a sleep system at varied degrees of firmness in a normal population. Ergonomics 45:798-815, 2002. DOI: 10.1080/00140130210159968.

91. Sigg DC, Coles JA Jr, Oeltgen PR, Iaizzo PA: Role of delta-opioid receptors on infarct size reduction in swine. American Journal of Physiology: Heart and Circulatory Physiology 282:H1953-1960, 2002. DOI: 10.1152/ajpheart.01045.2001.

90. Falkenberg JH, Iaizzo PA, McLoon LK: Muscle strength following direct injection of doxorubicin into rabbit sternocleidomastoid muscle in situ. Muscle & Nerve 25:735-741, 2002. DOI: 10.1002/mus.10082.

89. Hong JB, Iaizzo PA: Force assessment of the stimulated arm flexors: quantification of contractile properties. Journal of Medical Engineering & Technology 26:28-35, 2002. DOI: 10.1080/03091900110099558.

88. Cardozo RN, Durfee WK, Ardichwili A, Adams C, Erdman AG, Hoey M, Iaizzo PA, Mallick DN, Bar-Cohen A, Beachy R, Johnson A: Experiential education in new product design and business development. Journal of Product Innovation Management 19:4-17, 2002. DOI: 10.1111/1540-5885.1910004.

87. Day JW, Sakamoto C, Parry GJ, Lehmann-Horn F, Iaizzo PA: Force assessment in periodic paralysis after electrical muscle stimulation. Mayo Clinic Proceedings 77:232-240, 2002. DOI: 10.4065/77.3.232.

86. Hales J, Larson P, Iaizzo PA: Treatment of adult lumbar scoliosis with axial spinal unloading using the LTX3000 Lumbar Rehabilitation System. Spine 27:E71-79, 2002. DOI: 10.1097/00007632-200202010-00012.

85. Sigg DC, Coles JA Jr, Gallagher WJ, Oeltgen PR, Iaizzo PA: Opioid preconditioning: myocardial function and energy metabolism. Annals of Thoracic Surgery 72:1576-1582, 2001. DOI: 10.1016/S0003-4975(01)03084-3.

84. Falkenberg J, Podein RJ, Pardo X, Iaizzo PA: Surface EMG activity of the back musculature during axial spinal unloading using an LTX 3000 Lumbar Rehabilitation System. Electromyography and Clinical Neurophysiology 41:419-427, 2001. PMID: 11721297.

83. Sweney MT, Sigg DC, Tahvildari S, Iaizzo PA: Shiver suppression using focal hand warming in unanesthetized normal subjects. Anesthesiology 95:1089-1095, 2001. DOI: 10.1097/00000542-200111000-00011.

82. Falkenberg JH, Iaizzo PA, McLoon LK: Physiological assessment of muscle strength in vitro after direct injection of doxorubicin into rabbit sternocleidomastoid muscle. Movement Disorders 16:683-692, 2001. DOI: 10.1002/mds.1125.

81. Harlow HJ, Lohuis T, Beck TD, Iaizzo PA: Muscle strength in overwintering bears. Nature 409:997, 2001. DOI: 10.1038/35059165.

80. Thompson MD, Gallagher WJ, Iaizzo PA, Lanier WL: The effect of chronic dexamethasone-induced hyperglycemia and its acute treatment with insulin on brain glucose and glycogen concentrations in rats. Anesthesiology 93:1279-1284, 2000. PMID: 11046217.

79. Chinchoy E, Soule CL, Houlton AJ, Gallagher WJ, Hjelle MA, Laske TG, Morissett J, Iaizzo PA: Isolated four-chamber working swine heart model. Annals of Thoracic Surgery 70:1607-1614, 2000. DOI: 10.1016/S0003-4975(00)01977-9.

78. Jurkat-Rott K, Mitrovic N, Hang C, Kouzmekine A, Iaizzo P, Herzog J, Lerche H, Nicole S, Vale-Santos J, Chauveau D, Fontaine B, Lehmann-Horn F: Voltage-sensor sodium channel mutations cause hypokalemic periodic paralysis type 2 by enhanced inactivation and reduced current. Proceedings of National Academy of Science 97:9549-9554, 2000. DOI: 10.1073/pnas.97.17.9549.

77. Sigg DC, Iaizzo PA: Malignant hyperthermia phenotype: hypotension induced by succinylcholine in susceptible swine. Anesthesiology 92:1777-1788, 2000. DOI: 10.1097/00000542-200006000-00038.

76. Brinkmeier H, Krämer J, Krämer R, Iaizzo PA, Baur C, Lehmann-Horn F, Rüdel R: Malignant hyperthermia causing Gly2435Arg mutation of the ryanodine receptor facilitates ryanodine-induced calcium release in myotubes. British Journal of Anaesthesiology 83:855-861, 1999. DOI: 10.1093/bja/83.6.855.

75. Iaizzo PA, Jeon YM, Sigg DC: Facial warming increases the threshold for shivering. Journal of Neurosurgical Anesthesiology 11:231-239, 1999. DOI: 10.1097/00008506-199910000-00002.

74. Musley SK, Beebe DS, Komanduri V, Iaizzo PA, Belani KG: Hemodynamic and metabolic manifestations of acute endotoxin infusion in pigs with and without the malignant hyperthermia mutation. Anesthesiology 91:833-838, 1999. DOI: 10.1097/00000542-199909000-00036.

73. Iaizzo PA, Johnson BA, Nagao K, Gallagher WJ: 4-chloro-m-cresol triggers malignant hyperthermia in susceptible swine at doses greatly exceeding those found in drug preparations. Anesthesiology 90:1723-1732, 1999. DOI: 10.1097/00000542-199906000-00030.

72. Shailesh Kumar MV, Carr RJ, Komanduri V, Reardon RF, Beebe DS, Iaizzo PA, Belani KG: Differential diagnosis of thyroid crisis and malignant hyperthermia in an anesthetized porcine model. Endocrine Research 25:87-103, 1999. DOI: 10.1080/07435809909066132.

71. Sigg DC, Houlton AJ, Iaizzo PA: The potential for increased risk of infection due to the reuse of convective air-warming/cooling coverlets. Acta Anaesthesia Scandinavica 43:173-176, 1999. DOI: 10.1034/j.1399-6576.1999.430209.x.

70. McLoon LK, Falkenberg JH, Dykstra D, Iaizzo PA: Doxorubicin chemomyectomy as a treatment for cervical dystonia: histological assessment after direct injection into the sternocleidomastoid muscle. Muscle & Nerve 21:1457-1464, 1998. DOI: 10.1002/(sici)1097-4598(199811)21:11<1457::aid-mus14>3.0.co;2-y.

69. Podein RJ, Iaizzo PA: Applied forces and associated physiological responses induced by axial spinal unloading with the LTX 3000 Lumbar Rehabilitation System. Archives of Physical Medicine and Rehabilitation 79:505-513, 1998. DOI: 10.1016/S0003-9993(98)90063-6.

68. Hansen GL, Sparrow EM, Kalieta AL, Iaizzo PA: Using infrared imaging to assess the severity of pressure ulcers. Wounds: A Compendium of Clinical Research and Practice 10:43-53, 1998.

67. Chen MF, Niggeweg R, Iaizzo PA, Lehmann-Horn F, Jockusch H: Chloride conductance in mouse muscle is subject to post-transcriptional compensation of the functional C1- channel 1 gene dosage. Journal of Physiology 504:75-81, 1997. DOI: 10.1111/j.1469-7793.1997.075bf.x.

66. Kokate JY, Leland KJ, Sparrow EM, Iaizzo PA: Critical thresholds for pressure ulcer formation in a porcine model. Wounds: A Compendium of Clinical Research and Practice 9:111-121, 1997.

65. Otten W, Iaizzo PA, Eichinger HM: Effects of a high n-3 fatty acid diet on membrane lipid composition of heart and skeletal muscle in normal swine and in swine with the genetic mutation for malignant hyperthermia. Journal of Lipid Research 38:2023-2034, 1997. PMID: 9374125.

64. Hartmann S, Otten W, Kratzmair M, Seewald MJ, Iaizzo PA, Eichinger HM: Influences of breed, sex, and susceptibility to malignant hyperthermia on lipid composition of skeletal muscle and adipose tissue in swine. American Journal of Veterinary Research 58:738-743, 1997. PMID: 9215450.

63. Hansen GL, Sparrow EM, Kokate JY, Leland KJ, Iaizzo PA: Wound status evaluation using color image processing. IEEE Transactions on Medical Imaging 16:78-86, 1997. DOI: 10.1109/42.552057.

62. Janke AW, Kerkow TA, Griffiths HJ, Sparrow EM, Iaizzo PA: The biomechanics of gravity-dependent traction of the lumbar spine. Spine 22:253-260, 1997. DOI: 10.1097/00007632-199702010-00004.

61. Hansen GL, Sparrow EM, Kammamuri N, Iaizzo PA: Assessing wound severity with color and infrared imaging of reactive hyperemia. Wound Repair and Regeneration 4:386-392, 1996. DOI: 10.1046/j.1524-475X.1996.40317.x.

60. Brass TJ, Loushin MK, Day JW, Iaizzo PA: An improved method for muscle force assessment in neuromuscular disease. Journal of Medical Engineering and Technology 20:67-74, 1996. DOI: 10.3109/03091909609008382.

59. Iaizzo PA, Kehler CH, Carr RJ, Sessler DI, Belani KG: Prior hypothermia attenuates malignant hyperthermia in susceptible swine. Anesthesia and Analgesia 82:803-809, 1996. DOI: 10.1097/00000539-199604000-00022.

58. Iaizzo PA, Kehler CH, Zink RS, Belani KG, Sessler DI: Thermal response in acute porcine malignant hyperthermia. Anesthesia and Analgesia 82:782-789, 1996. DOI: 10.1097/00000539-199604000-00019.

57. Lanier WL, Albrecht RF, Iaizzo PA: Divergence of intracranial and central venous pressures in lightly anesthetized, tracheally intubated dogs that move in response to a noxious stimulus. Anesthesiology 84:605-613, 1996. DOI: 10.1097/00132586-199704000-00027.

56. Iaizzo PA, Kveen GL, Kokate JY, Leland KJ, Hansen GL, Sparrow EM: Prevention of pressure ulcers by focal cooling: histological assessment in a porcine model. Wounds: A Compendium of Clinical Research and Practice 7:161-169, 1995.

55. Hofer RE, Lanier WL, Iaizzo PA: The temporal relationship between intraocular pressure and extraocular muscle activation in cats. Pflügers Archive 430:779-786, 1995. DOI: 10.1007/BF00386176.

54. Kokate JY, Leland KJ, Held AM, Hansen GL, Kveen GL, Johnson BA, Wilke MS, Sparrow EM, Iaizzo PA: Temperature-modulated pressure ulcers: a porcine model. Archives of Physical Medicine and Rehabilitation 76:666-673, 1995. DOI: 10.1016/S0003-9993(95)80637-7.

53. Verhaegen M, Iaizzo PA, Todd MM: A comparison of the effects of hypothermia, pentobarbital, and isoflurane on cerebral energy stores at the time of ischemic depolarization. Anesthesiology 82:1209-1215, 1995. DOI: 10.1097/00000542-199505000-00016.

52. Lerche H, Fahlke C, Iaizzo PA, Lehmann-Horn F: Characterization of the high-conductance Ca(2+)-activated K+ channel in adult human skeletal muscle. Pflügers Archive 429:738-747, 1995. DOI: 10.1007/BF00373997.

51. Yamada H, Transfeldt EE, Tamaki T, Nishiura H, Taylor BA, Torres F, Iaizzo PA: General anesthetic effects on compound muscle action potentials elicited by single or dual spinal stimulation. Journal of Spinal Disorders 8:157-162, 1995. PMID: 7606124.

50. Wedel DJ, Quinlan JG, Iaizzo PA: Clinical effects of intravenously administered dantrolene. Mayo Clinic Proceedings 70:241-246, 1995. DOI: 10.4065/70.3.241.

49. Iaizzo PA, Quasthoff S, Lehmann-Horn F: Differential diagnosis of periodic paralysis aided by in vitro myography. Neuromuscular Disorders 5:115-124, 1995. DOI: 10.1016/0960-8966(94)00036-9.

48. Yamada H, Transfeldt EE, Tamaki T, Torres F, Iaizzo PA: The effects of volatile anesthetics on the relative amplitudes and latencies of spinal and muscle potentials evoked by transcranial magnetic stimulation. Spine 19:1512-1517, 1994. DOI: 10.1097/00007632-199407000-00018.

47. Iaizzo PA, Wedel DJ: Response to succinylcholine in porcine malignant hyperthermia. Anesthesia and Analgesia 79:143-151, 1994. DOI: 10.1213/00000539-199407000-00027.

46. Lanier WL, Iaizzo PA, Milde JH, Sharbrough FW: The cerebral and systemic effects of movement in response to a noxious stimulus in lightly anesthetized dogs. Possible modulation of cerebral function by muscle afferents. Anesthesiology 80:392-401, 1994. DOI: 10.1097/00000542-199402000-00019.

45. Beebe DS, Gauthier RL, DeMars JJ, Iaizzo PA: Lower extremity hypothermia is beneficial during infra-renal aortic cross-clamping in pigs. Anesthesia and Analgesia 77:241-249, 1993. DOI: 10.1213/00000539-199308000-00006.

44. Otten W, Wirth C, Iaizzo PA, Eichinger HM: A high omega 3 fatty acid diet alters the fatty acid composition of heart, liver, kidney, adipose tissue and skeletal muscle in swine. Annals of Nutrition and Metabolism 37:134-141, 1993. DOI: 10.1159/000177761.

43. Wedel DJ, Gammel SA, Milde JH, Iaizzo PA: Delayed onset of malignant hyperthermia induced by isoflurane and desflurane compared with halothane in susceptible swine. Anesthesiology 78:1138-1144, 1993. DOI: 10.1097/00000542-199306000-00018.

42. Seewald MJ, Iaizzo PA, Heisswolf E, Eichinger HM: Effects of meat quality and storage on the breakdown of adenosine triphosphate in muscle from swine. Meat Science 35:47-61, 1993. DOI: 10.1016/0309-1740(93)90069-T.

41. Zink RS, Iaizzo PA: Convective warming therapy does not increase the risk of wound contamination in the operating room. Anesthesia and Analgesia 76:50-53, 1993. DOI: 10.1213/00000539-199301000-00009.

40. Iaizzo PA, Seewald MJ, Powis G, Van Dyke RA: The effects of sevoflurane on intracellular Ca2+ regulation in rat hepatocytes. Toxicology Letters 66:81-88, 1993. DOI: 10.1016/0378-4274(93)90082-9.

39. Deufel T, Müller-Felber W, Pongratz DE, Hübner G, Johnson K, Iaizzo PA, Lehmann-Horn F: Chronic myopathy in a patient suspected of carrying two malignant hyperthermia susceptibility (MHS) mutations. Neuromuscular Disorders 2:389-396, 1992. DOI: 10.1016/S0960-8966(06)80010-6.

38. Pozos RS, Iaizzo PA: Effects of topical anesthesia on essential tremor. Electromyography and Clinical Neurophysiology 32:369-372, 1992. PMID: 1526217.

37. Iaizzo PA, Pozos RS: Analysis of multiple EMG and acceleration signals of various record lengths as a means to study pathological and physiological oscillations. Electromyography and Clinical Neurophysiology 32:359-367, 1992. PMID: 1526216.

36. Iaizzo PA: The effects of halothane and isoflurane on intracellular Ca2+ regulation in cultured cells with characteristics of vascular smooth muscle. Cell Calcium 13:513-520, 1992. DOI: 10.1016/0143-4160(92)90019-O.

35. Lanier WL, Iaizzo PA, Murray MJ: The effects of convective cooling and rewarming on systemic and central nervous system physiology in isoflurane-anesthetized dogs. Resuscitation 23:121-136, 1992. DOI: 10.1016/0300-9572(92)90197-K.

34. Pozos RS, Iaizzo PA: Shivering and pathological and physiological clonic oscillations of the human ankle. Journal of Applied Physiology 71:1929-1932, 1991. DOI: 10.1152/jappl.1991.71.5.1929.

33. Iaizzo PA, Wedel DJ, Gallagher WJ: In vitro contracture testing for determination of susceptibility to malignant hyperthermia: a methodological update. Mayo Clinic Proceedings 66:998-1004, 1991. DOI: 10.1016/S0025-6196(12)61722-4.

32. Franke C, Iaizzo PA, Hatt H, Spittelmeister W, Ricker K, Lehmann-Horn F: Altered Na+ channel activity and reduced Cl- conductance cause hyperexcitability in recessive generalized myotonia (Becker). Muscle & Nerve 14:762-770, 1991. DOI: 10.1002/mus.880140811.

31. Seewald MJ, Eichinger HM, Iaizzo PA: Malignant hyperthermia: an altered phospholipid and fatty acid composition in muscle membranes. Acta Anaesthesiologica Scandinavica 35:380-386, 1991. DOI: 10.1111/j.1399-6576.1991.tb03314.x.

30. Seewald MJ, Eichinger HM, Lehmann-Horn F, Iaizzo PA: Characterization of swine susceptible to malignant hyperthermia by in vivo, in vitro and post-mortem techniques. Acta Anaesthesiologica Scandinavica 35:345-349, 1991. DOI: 10.1111/j.1399-6576.1991.tb03303.x.

29. Lehmann-Horn F, Iaizzo PA, Hatt H, Franke C: Altered gating and conductance of Na+ channels in hyperkalemic periodic paralysis. Pflügers Archive 418:297-299, 1991. DOI: 10.1007/BF00370530.

28. Iaizzo PA, Franke C, Hatt H, Spittelmeister W, Ricker K, Rüdel R, Lehmann-Horn F: Altered sodium channel behaviour causes myotonia in dominantly inherited myotonia congenita. Neuromuscular Disorders 1:47-53, 1991. DOI: 10.1016/0960-8966(91)90042-Q.

27. Iaizzo PA, Seewald MJ, Olsen R, Wedel DJ, Chapman DE, Berggren M, Eichinger HM, Powis G: Enhanced mobilization of intracellular Ca2+ induced by halothane in hepatocytes isolated from swine susceptible to malignant hyperthermia. Anesthesiology 74:531-538, 1991. DOI: 10.1097/00000542-199103000-00023.

26. Wedel DJ, Iaizzo PA, Milde JH: Desflurane is a trigger of malignant hyperthermia in susceptible swine. Anesthesiology 74:508-512, 1991. DOI: 10.1097/00000542-199103000-00020.

25. Olsen RA, Seewald MJ, Melder DC, Berggren M, Iaizzo PA, Powis G: Platelet-derived growth factor blocks the increase in intracellular free Ca2+ caused by calcium ionophores and a volatile anesthetic agent in Swiss 3T3 fibroblasts without altering toxicity. Toxicology Letters 55:117-125, 1991. DOI: 10.1016/0378-4274(91)90033-3.

24. Iaizzo PA, Poppele RE: Twitch relaxation of the cat soleus muscle at different lengths and temperatures. Muscle & Nerve 13:1105-1112, 1990. DOI: 10.1002/mus.880131204.

23. Lehmann-Horn F, Iaizzo PA: Are myotonias and periodic paralyses associated with susceptibility to malignant hyperthermia? British Journal of Anaesthesia 65:692-697, 1990. DOI: 10.1093/bja/65.5.692.

22. Iaizzo PA, Olsen RA, Seewald MJ, Powis G, Stier A, Van Dyke RA: Transient increases of intracellular Ca2+ induced by volatile anesthetics in rat hepatocytes. Cell Calcium 11:515-524, 1990. DOI: 10.1016/0143-4160(90)90027-R.

21. Quinlan JG, Wedel DJ, Iaizzo PA: Multiple-pulse stimulation and dantrolene in malignant hyperthermia. Muscle & Nerve 13:904-908, 1990. DOI: 10.1002/mus.880131003.

20. Iaizzo PA: Histochemical and physiological properties of Rana temporaria tibialis anterior and lumbricalis IV muscle fibres. Journal of Muscle Research and Cell Motility 11:281-292, 1990. DOI: 10.1007/BF01766666.

19. Lanier WL, Iaizzo PA, Milde JH: The effects of intravenous succinylcholine on cerebral function and muscle afferent activity following complete ischemia in halothane-anesthetized dogs. Anesthesiology 73:485-490, 1990. DOI: 10.1097/00000542-199009000-00019.

18. Franke C, Hatt H, Iaizzo PA, Lehmann-Horn F: Characteristics of Na+ channels and Cl- conductance in resealed muscle fibre segments from patients with myotonic dystrophy. Journal of Physiology 425:391-405, 1990. DOI: 10.1113/jphysiol.1990.sp018110.

17. Lehmann-Horn F, Iaizzo PA, Franke C, Hatt H, Spanns F: Schwartz-Jampel syndrome: II. Na+ channel defect causes myotonia. Muscle & Nerve 13:528-535, 1990. DOI: 10.1002/mus.880130609.

16. Powis G, Seewald MJ, Sehgal I, Iaizzo PA, Olsen RA: Platelet-derived growth factor stimulates non-mitochondrial Ca2+ uptake and inhibits mitogen-induced Ca2+ signaling in Swiss 3T3 fibroblasts. Journal of Biological Chemistry 265:10266-10273, 1990. PMID: 2113051.

15. Quinlan JG, Iaizzo PA, Gronert GA, Lambert EH: Twitch response in a myopathy with impaired relaxation but no myotonia. Muscle & Nerve 13:326-329, 1990. DOI: 10.1002/mus.880130408.

14. Iaizzo PA, Seewald MJ, Powis G, Van Dyke RA: The effects of volatile anesthetics on Ca++ mobilization in rat hepatocytes. Anesthesiology 72:504-509, 1990. DOI: 10.1097/00000542-199003000-00019.

13. Iaizzo PA, Lehmann-Horn F: The correlation between electrical after-activity and slowed relaxation in myotonia. Muscle & Nerve 13:240-246, 1990. DOI: 10.1002/mus.880130311.

12. Lehmann-Horn F, Iaizzo PA: Resealed fiber segments for the study of the pathophysiology of human skeletal muscle. Muscle & Nerve 13:222-231, 1990. DOI: 10.1002/mus.880130309.

11. Lanier WL, Iaizzo PA, Milde JH: Cerebral function and muscle afferent activity following intravenous succinylcholine in dogs anesthetized with halothane: the effects of pretreatment with a defasciculating dose of pancuronium. Anesthesiology 71:87-95, 1989. DOI: 10.1097/00000542-198907000-00016.

10. Iaizzo PA, Seewald M, Oakes SG, Lehmann-Horn F: The use of Fura-2 to estimate myoplasmic [Ca2+] in human skeletal muscle. Cell Calcium 10:151-158, 1989. DOI: 10.1016/0143-4160(89)90069-9.

9. Iaizzo PA, Lehmann-Horn F: The in vitro determination of susceptibility to malignant hyperthermia. Muscle & Nerve 12:184-190, 1989. DOI: 10.1002/mus.880120304.

8. Iaizzo PA, Lehmann-Horn F, Taylor SR, Gallant EM: Malignant hyperthermia: effects of halothane on the surface membrane. Muscle & Nerve 12:178-183, 1989. DOI: 10.1002/mus.880120303.

7. Quinlan JG, Iaizzo PA, Lambert EH, Gronert GA: Ankle dorsiflexor twitch properties in malignant hyperthermia. Muscle & Nerve 12:119-125, 1989. DOI 10.1002/mus.880120206.

6. Oakes SG, Iaizzo PA, Richelson E, Powis G: Histamine-induced intracellular free Ca++, inositol phosphates and electrical changes in murine N1E-115 neuroblastoma cells. Journal of Pharmacology and Experimental Therapeutics 247:114-121, 1988. PMID: 3262737.

5. Iaizzo PA: The effects of temperature on relaxation in frog skeletal muscle: the role of parvalbumin. Pflügers Archive 412:195-202, 1988. DOI: 10.1007/BF00583750.

4. Iaizzo PA, Klein W, Lehmann-Horn F: Fura-2 detected myoplasmic calcium and its correlation with contracture force in skeletal muscle from normal and malignant hyperthermia susceptible pigs. Pflügers Archive 411:648-653, 1988. DOI: 10.1007/BF00580861.

3. Quinlan JG, Iaizzo PA, Gronert GA, Taylor SR: Use of dantrolene plus multiple pulses to detect stress-susceptible porcine muscle. Journal of Applied Physiology 60:1313-1320, 1986. DOI: 10.1152/jappl.1986.60.4.1313.

2. Iaizzo PA, Pozos RS: Exercise-induced amplitude modification of physiological action tremor of the ankle. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology 53:1164-1170, 1982. DOI: 10.1152/jappl.1982.53.5.1164.

1. Pozos RS, Iaizzo PA, Petry RW: Physiological action tremor of the ankle. Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology 52:226-230, 1982. DOI: 10.1152/jappl.1982.52.1.226.

Review Articles

5. Mallick DN, Adams C, Durfee WK, Erdman A, Iaizzo PA: An experiential approach to preparing students for leadership in managing technology. Decision Line, pages 4-22, July 2004.

4. Sigg DC, Hasinoff IK, Iaizzo PA: Prolonged paralysis and muscular weakness in critically ill patients: Part II. Neuromuscular blockers. The American Journal of Anesthesiology 27:321-328, 2000.

3. Sigg DC, Hasinoff IK, Iaizzo PA: Prolonged paralysis and muscular weakness in critically ill patients; Part I. The American Journal of Anesthesiology 27:265-272, 2000.

2. Iaizzo PA, Palahniuk RJ, Cameron CB, Belani KG: Malignant hyperthermia. Journal of Anaesthesiology - Clinical Pharmacology 9:95-104, 1993.

1. Iaizzo PA, Palahniuk RJ: Malignant hyperthermia: diagnosis, treatment, genetics and pathophysiology. Investigative Radiology 26:1013-1018, 1991. PMID: 1743909

Books

7. Iaizzo PA (Editor). Engineering in Medicine: Advances and Opportunities, Elsevier, Cambridge, MA 2019.

6. Durfee WK and Iaizzo PA (Editors), Medical Device Innovation Handbook, Medical Devices Center, University of Minnesota, 2015.

5. Iaizzo PA (Editor). The Handbook of Cardiac Anatomy, Physiology, and Devices, 3rd edition. Springer, New York, NY 2015.

4. Iaizzo PA, Bianco RW, Hill AJ, St. Louis JD (Editors). Heart Valves: From Design to Clinical Implantation, Springer Science + Media, New York, NY 2013.

3. Sigg DS, Iaizzo PA, Xiao YF, He B (Editors). Cardiac Electrophysiology Methods and Models, Springer, Inc. 2010.

2. Iaizzo PA (Editor). The Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, New York, NY 2009.

1. Iaizzo PA (Editor). The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press Inc., Totowa, NJ 2005.

Book Chapters

84. Deakyne AJ, Iles TL, Iaizzo PA: A helpful relocation function for augmenting teaching in a multiple user shared virtual environment. In: Proceedings of the Future Technologies Conference (FTC) 2021, Vol. 3, Spring Nature Switzerland, 2021. DOI: 10.1007/978-3-030-89912-7_29.

83. Deakyne AJ, Valenzuela T, Iaizzo PA: Development of anaglyph 3D functionality for cost-effective virtual reality anatomical education. In: Intelligent Computing, Lecture Notes in Networks and Systems. Arai K, (ed.) Springer Nature, Chapter 28, pages 390-398, 2021. DOI: 10.1007/978-3-030-80129-8_28.

82. Garshelis DL, Noyce KV, Ditmer MA, Coy PL, Tri AN, Laske TG, Iaizzo PA: Remarkable adaptations of the American Black Bear help explain why it is the most common bear: a long-term study from the center of its range. In: Bears of the World: Ecology, Conservation and Management. Penteriani V, Melletti M (eds.), Cambridge University Press, Chapter 5, pages 53-62, 2020.

81. Gaasedelen EN, Deakyne AJ, Mattson AR, Mattison LM, Holm MA, Zhingre Sanchez JD, Schmidt MM, Bateman MG, Iles TL, Iaizzo PA: Virtual reality and visualization of 3D reconstructed medical imaging: learning variations within detailed human anatomies. In: Proceedings of the Future Technologies Conference (FTC) 2020, Vol. 3. Arai K et al. (eds.), Springer Nature Switzerland, 2021. DOI: 10.1007/978-3-030-63092-8_14.

80. Iaizzo PA: Introduction to neurophysiology. In: Handbook of Neural Engineering, 3rd edition. He B (ed.), Springer Science + Business Media, Chapter 1, pages 1-64, 2020.

79. Iaizzo PA, Durfee WK: Creating an environment for developing and testing surgical devices within an academic medical center. In: Success in Academic Surgery: Innovation and Entrepreneurship. Cohen M (ed.), Springer Nature, 2019.

78. Durfee WK, Iaizzo PA: Medical applications of 3D printing. In: Engineering in Medicine: Advances and Opportunities. Elsevier, Chapter 21, pages 527-544, 2018.

77. Durfee WK, Iaizzo PA: Educating innovators of medical technologies. In: Engineering in Medicine: Advances and Opportunities. Elsevier, Chapter 20, pages 511-526, 2018.

76. Durfee WK, Iaizzo PA: The medical device innovation process. In: Engineering in Medicine: Advances and Opportunities. Elsevier, Chapter 19, pages 495-510, 2018.

75. Holm MA, Iaizzo PA: Importance of human cadaver studies in education and medical device research: insights derived from various imaging studies and modalities. In: Engineering in Medicine: Advances and Opportunities. Elsevier, Chapter 10, pages 255-282, 2018.

74. Zhingre Sanchez JD, Bateman MG, Iaizzo PA: Engineering and technologies associated with cardiac valve repair and replacement therapies. In: Engineering in Medicine: Advances and Opportunities. Elsevier, Chapter 9, pages 219-254, 2018.

73. Gaasedelen EN, Iaizzo PA: 3D graphics to virtual reality in medicine: opportunities and prospective. In: Engineering in Medicine: Advances and Opportunities. Elsevier, Chapter 8, pages 201-218, 2018.

72. Mattison LM, Howard BT, Iaizzo PA: Electroporation ablative therapy as a clinical tool: an old technology revisited. In: Engineering in Medicine: Advances and Opportunities. Elsevier, Chapter 7, pages 179-200, 2018.

71. Mattson AR, Eggen MD, Iaizzo PA: The cardiac pacemaker: a crossroads of engineering and medicine. In: Engineering in Medicine: Advances and Opportunities. Elsevier, Chapter 6, pages 153-178, 2018.

70. Bateman MG, Iles TL, Iaizzo PA: Advancing the design and testing of novel cardiac device technologies using the Visible Heart®. In: Engineering in Medicine: Advances and Opportunities. Elsevier, Chapter 5, pages 119-152, 2018.

69. Shaffer AW, Mattison LM, Spratt JR, Iles TL, Kerns N, Bateman MG, Huddleston SJ, Kelly RF, John R, Liao KK, Iaizzo PA: A new era for improving cardiothoracic transplantations. In: Engineering in Medicine: Advances and Opportunities. Elsevier, Chapter 3, pages 55-82, 2018.

68. Iaizzo PA: Cardiac devices and technologies: continued rapid rates of development. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 44, pages 787-794, 2015.

67. Howard SA, Bateman MG, Laske TG, Iaizzo PA: Current status of development and regulatory approval of cardiac devices. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 42, pages 765-776, 2015.

66. Bateman MG, Eggen MD, Spencer JH, Iles TL, Iaizzo, PA: The use of isolated heart models and anatomic specimens as means to enhance the design and testing of cardiac devices. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 41, pages 751-764, 2015.

65. Mattison LM, Laske TG, Iaizzo PA: Transcatheter valve repair and replacement. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 36, pages 671-684, 2015.

64. Skadsberg ND, He B, Laske TG, Ramanathan C, Iaizzo PA: Cardiac mapping technology. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 32, pages 599-614, 2015.

63. Laske TG, Legreid Dopp A, Eggen MD, Iaizzo PA: Pacing and defibrillation. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 30, pages 543-576, 2015.

62. Iaizzo PA, Mahre MA: Historical perspective of cardiovascular devices and techniques associated with the University of Minnesota. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 25, pages 439-456, 2015.

61. Loushin MK, Quill JL, Iaizzo PA: Mechanical aspects of cardiac performance. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 20, pages 335-360, 2015.

60. Vieau S, Iaizzo PA: Basic ECG theory, 12-lead recordings and their interpretation. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 19, pages 321-334, 2015.

59. Howard BT, Iles TL, Coles Jr JA, Sigg DC, Iaizzo PA: Reversible and irreversible damage of the myocardium: ischemia/reperfusion injury and cardioprotection. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 16, pages 279-294, 2015.

58. Iaizzo PA, Fitzgerald K: Autonomic nervous system. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 14, pages 235-250, 2015.

57. Laske TG, Shrivastav M, Iaizzo PA: The cardiac conduction system. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 13, pages 215-234, 2015.

56. Richardson ES, Hill AJ, Skadsberg ND, Ujhelyi M, Xiao YF, Iaizzo PA: The pericardium. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 9, pages 163-174, 2015.

55. Spencer JH, Anderson SA, Lahm R, Iaizzo PA: The coronary vascular system and associated medical devices. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 8, pages 137-162, 2015.

54. Bateman MG, Quill JL, Hill AJ, Iaizzo PA: Detailed anatomical and functional features of the cardiac veins. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 7, pages 115-136, 2015.

53. Hill AJ, Iaizzo PA: Comparative cardiac anatomy. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 6, pages 89-114, 2015.

52. Iaizzo PA: General features of the cardiovascular system. In: Handbook of Cardiac Anatomy, Physiology and Devices, 3rd edition. Springer, Chapter 1, pages 3-14, 2015.

51. Mulligan LJ, Lalonde JP, Iaizzo PA, Eggen MD: Electro-physiological solutions for cardiac disease. In: Biomedical Technology and Devices, 2nd edition. Moore JE and Maitland DJ (eds.), CRC Press, Chapter 22, 2013. DOI: 10.1201/b15085-28

50. Howard SA, Bateman MG, Laske TG, Iaizzo PA: Successful development and regulatory approval of replacement cardiac valves. In: Heart Valves: From Design to Clinical Implantation. Springer Science + Business Media, Chapter 16, pages 381-402, 2013.

49. Bateman MG, Hill AJ, Quill JL, Eggen MD, Rolfes CD, Iaizzo PA: The use of isolated heart models and anatomic specimens as means to enhance the design and testing of cardiac valve therapies. In: Heart Valves: From Design to Clinical Implantation. Springer Science + Business Media, Chapter 15, pages 359-380, 2013.

48. Ahlberg SA, Bateman MG, Eggen MD, Quill JL, Richardson ES, Iaizzo PA: Animal models for cardiac valve research. In: Heart Valves: From Design to Clinical Implantation. Springer Science + Business Media, Chapter 14, pages 343-358, 2013.

47. Bateman MG, Quill JL, Hill AJ, Iaizzo PA: The anatomy and function of the semilunar valves. In: Heart Valves: From Design to Clinical Implantation. Springer Science + Business Media, Chapter 2, pages 27-44, 2013.

46. Bateman MG, Quill JL, Hill AJ, Iaizzo PA: The anatomy and function of the atrioventricular valves. In: Heart Valves: From Design to Clinical Implantation. Springer Science + Business Media, Chapter 1, pages 3-26, 2013.

45. Iaizzo PA: Introduction to neurophysiology. In: Handbook of Neural Engineering, 2nd edition. He B (ed.), Springer Science + Business Media, pages 1-86, 2013.

44. Benscoter MA, Iaizzo PA: Cardiac pacing: a review chapter. In: Horizons in World Cardiovascular Research. Nova Publishers, Volume 2, 2011.

43. Rolfes C, Howard S, Goff R, Iaizzo PA: Localized drug delivery for cardiothoracic surgery. In: Current Concepts in General Thoracic Surgery. Cagini L (ed.), InTech, Chapter 14, pages 279-303, 2012.

42. Iaizzo PA, Durfee WK: Functional force assessment of skeletal muscles. In: Handbook of Medical Technology. Springer, Chapter 14, pages 273-287, 2011.

41. Bateman M, Howard SA, Rolfes C, Laske TG, Iaizzo PA: Cardiac devices and testing. In: Handbook of Medical Technology. Hoffman KP (ed.), Springer, Chapter 43, pages 855-876, 2011.

40. Skadsberg ND, Hill AJ, Iaizzo PA: Isolated heart models. In: Cardiac Electrophysiology Methods and Models. Springer, Chapter 12, pages 249-260, 2010.

39. Iaizzo PA, Laske TG: Anatomy and physiology of the cardiac conduction system. In: Cardiac Electrophysiology Methods and Models. Springer, Chapter 4, pages 73-90, 2010.

38. Iaizzo PA: Emerging cardiac devices and technologies. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 38, pages 631-644, 2009.

37. Hill AJ, Laske TG, Iaizzo PA: Transcatheter valve repair and replacement. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 33, pages 561-570, 2009.

36. Skadsberg ND, He B, Laske TG, Iaizzo PA: Cardiac mapping technology. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 29, pages 499-510, 2009.

35. Laske TG, Legreid Dopp AM, Iaizzo PA: Pacing and defibrillation. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 27, pages 443-474, 2009.

34. Iaizzo PA, Mahre MA: A historical perspective of cardiovascular devices and techniques associated with the University of Minnesota. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 23, pages 365-382, 2009.

33. Loushin MK, Quill JL, Iaizzo PA: Mechanical aspects of cardiac performance. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 18, pages 271-296, 2009.

32. Dupre A, Vieau SA, Iaizzo PA: Basic ECG theory, 12-lead recordings and their interpretation. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 17, pages 257-270, 2009.

31. Coles Jr JA, Sigg DC, Iaizzo PA: Reversible and irreversible damage of the myocardium: new ischemic syndromes, ischemia/reperfusion injury, and cardioprotection. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 14, pages 219-230, 2009.

30. Fitzgerald K, Wilson RF, Iaizzo PA: Autonomic nervous system. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 12, pages 177-190, 2009.

29. Laske TG, Shrivastav M, Iaizzo PA: The cardiac conduction system. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 11, pages 159-176, 2009.

28. Richardson E, Hill AJ, Skadsberg ND, Ujhelyi M, Xiao YF, Iaizzo PA: The pericardium. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 8, pages 125-136, 2009.

27. Anderson SE, Lahm R, Iaizzo PA: The coronary vascular system and associated medical devices. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 7, pages 109-124, 2009.

26. Hill AJ, Iaizzo PA: Comparative cardiac anatomy. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 6, pages 87-108, 2009.

25. Iaizzo PA: General features of the cardiovascular system. In: Handbook of Cardiac Anatomy, Physiology, and Devices, 2nd edition. Springer, Chapter 1, pages 3-12, 2009.

24. Durfee WK and Iaizzo PA: Rehabilitation and muscle testing. In: Encyclopedia of Medical Devices and Instrumentation, 2nd edition. John Wiley & Sons, pages 62-71, 2006.

23. Iaizzo PA: Emerging cardiac devices and technologies. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 33, pages 445-457, 2005.

22. Skadsberg ND, Laske TG, Iaizzo PA: Cardiac mapping systems. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 25, pages 361-369, 2005.

21. Laske TG, Legreid A, Iaizzo PA: Pacing and defibrillation. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 23, pages 323-348, 2005.

20. McManus D, Mahre MA, Iaizzo PA: Historical perspective of cardiovascular devices and techniques. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 20, pages 273-285, 2005.

19. Loushin MK, Iaizzo PA: Mechanical aspects of cardiac performance. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 16, pages 203-222, 2005.

18. Dupre A, Vincent S., Iaizzo PA: Basic ECG theory, recordings and interpretation. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 15, pages 191-201, 2005.

17. Coles JA Jr, Sigg DC, Iaizzo PA: Reversible and irreversible damage of the myocardium: new ischemic syndromes, ischemia/reperfusion injury, and cardioprotection. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 12, pages 161-170, 2005.

16. Fitzgerald K, Iaizzo PA: Autonomic nervous system. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 10, pages 137-148, 2005.

15. Laske, TG, Iaizzo PA: The cardiac conduction system. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 9, pages 123-136, 2005.

14. Chinchoy E, Ujhelyi M, Hill AJ, Skadsberg ND, Iaizzo PA: The pericardium. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 7, pages 101-110, 2005.

13. Lahm R, Iaizzo PA: The coronary system and associated medical devices. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 6, pages 93-100, 2005.

12. Hill AJ, Iaizzo PA: Comparative cardiac anatomy. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 5, pages 81-91, 2005.

11. Iaizzo PA: General features of the cardiovascular system. In: The Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press, Chapter 1, pages 3-11, 2005.

10. Sigg, DC, Coles JA, Iaizzo PA: Surgical myocardial protection: Part II. From ischemic preconditioning to gene therapy: emerging experimental cardioprotective approaches. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume XVI, Chapter 5, pages 63-80, 2002.

9. Coles JA Jr, Sigg DC, Bittner HB, Iaizzo PA: Surgical myocardial protection: Part I. Physiological basis and clinical relevance. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume XVI, Chapter 3, pages 35-48, 2002.

8. Iaizzo PA: Blood and blood flow. In: Malignant Hyperthermia. Schulte am Esch J, Scholz J, Wappler F (eds.), Pabst Science Publishers, pages 148-153, 2000.

7. Sigg D, Hausmann ON, Falkenberg JH, Iaizzo PA: Low back pain, part III: treatment approaches. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume XIV, Chapter 12, pages 183-200, 2000.

6. Sigg D, Hausmann ON, Falkenberg JH, Iaizzo PA: Low back pain, part II: differential diagnoses and patient evaluation. In: Progress in Anesthesiology, Dannemiller Memorial Education Foundation. Volume XIV, Chapter 10, pages 151-164, 2000.

5. Sigg D, Hausmann ON, Falkenberg JH, Iaizzo PA: Low back pain, part I: Anatomy, physiology, and pathophysiology. In: Progress in Anesthesiology, Dannemiller Memorial Education Foundation. Volume XIV, Chapter 8, pages 115-128, 2000.

4. Sigg D, Hasinoff IK, Iaizzo PA: Weakness in the ICU paralysis syndrome: differential diagnosis. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume XII, Chapter 8, pages 127-156, 1998.

3. Iaizzo PA: Methods for monitoring modulations in intracellular [Ca2+]. In: Anesthesia: Biological Foundations. Yaksh TL, Lynch C III, Zapol WM, Maze M, Biebuyck JF, Saidman LJ (eds.), Raven Press, Chapter 24, pages 399-415, 1997.

2. Iaizzo PA, Day JW: The potential for complications due to anesthesia in patients with a muscle disorder. In: Progress in Anesthesiology. Dannemiller Memorial Education Foundation, Volume X, Chapter 9, pages 151-172, 1996.

1. Pozos RS, Iaizzo PA, Danzl DF, Mills W III: Limits of tolerance to cold. In: Handbook of Physiology: Environmental Physiology. Fregly MJ, Blatteis CM (eds.), Oxford University Press, Chapter 25, pages 557-578, 1996.

Invited Articles

26. Shrivastava D, Hanson T, Schlentz R, Gallagher W, Snyder C, DelaBarre L, Prakash S, Iaizzo P, Vaughan JT: MR safety and in vivo thermal characterization of an RF coil at 9.4T. ASME 2007 Summer Bioengineering Conference, June 20-24, 2007.

25. Laske T, Bonhoeffer P, Iaizzo P: Visualization of transcatheter valve implantation in isolated human and porcine hearts. 5th World Congress of Biomechanics, pages 407-410, 2006.

24. Skadsberg ND, Coles Jr JA, Iaizzo PA: Electrophysiologic assessment of right ventricular cardiac pacing sites employing non-contact electrical mapping. International Journal of Bioelectromagnetism 7:325-328, 2005.

23. Iaizzo PA, Laske TG: The Visible Heart™: The collaborative development and use of this educational tool by the University of Minnesota and Medtronic. Proceedings of the Second Joint EMBS/BMES Conference Houston TX, pages 2625-2627, 2002.

22. Schulte-Mattler WJ, Iaizzo PA: NIR-Spektroskopie und stimulierte Kraftmessung. Proceedings of the Tage der Elektrotechnik der Fachhochschule Anhalt. Hoffman KP, Weber B (Hrsg.), 1998.

21. Iaizzo PA: Assessment of stimulated muscle force in humans. In: Proceedings of the Tage der Electrotechnik der Fachhochschule Anhalt. Hoffmann K-P, Weber B (eds.), pages 1-11, 1997.

20. Kokate J, Leland K, Johnson BA, Kveen G, Oakes SG, Sparrow EM, Iaizzo PA: Thermoregulation of the skin in a porcine model. In: Proceedings of the Sixth International Conference on Environmental Ergonomics. Frim J, Ducharme MB, Tikuisis P (eds.), Government of Canada Catalogue # D2-47/1994E, pages 158-159, 1994.

19. Shireman BL, Oakes SG, Iaizzo PA, Sparrow EM: A heat flux mannequin instrumented with 28 thermal guarded calorimeters. In: Proceedings of the Sixth International Conference on Environmental Ergonomics. Frim J, Ducharme MB, Tikuisis P (eds.), Government of Canada Catalogue # D2-47/1994E, pages 180-181, 1994.

18. Seiffert DJ, Oakes SG, Ziaimehr H, Stapf D, Iaizzo PA, Sparrow EM: A thermoelectric-based forced -air delivery system to induce controlled changes in body temperatures. In: Proceedings of the Sixth International Conference on Environmental Ergonomics. Frim J, Ducharme MB, Tikuisis P (eds.), Government of Canada Catalogue # D2-47/1994E, pages 118-119, 1994.

17. Shireman BL, Oakes SG, Iaizzo PA, Sparrow EM: Laboratory simulations of air jet dynamics found in forced-air warming systems. In: Proceedings of the Sixth International Conference on Environmental Ergonomics. Frim J, Ducharme MB, Tikuisis P (eds.), Government of Canada Catalogue # D2-47/1994E, pages 152-153, 1994.

16. Iaizzo PA, Held AM, Zink RS, Williams GW, Leon AS, Palahniuk RJ: Exercise-induced heat stress: passive recovery or subsequent treatment. In: Proceedings of the Sixth International Conference on Environmental Ergonomics. Frim J, Ducharme MB, Tikuisis P (eds.), Government of Canada Catalogue # D2-47/1994E, pages 8-9, 1994.

15. Iaizzo PA: The physiology and biochemistry of skeletal muscle contraction and correlation to malignant hyperthermia. In: Anaesthesia and Pharmacogenetic Diseases: Malignant Hyperthermia. Minerva Anaesthesiologica 60:131-136, 1994.

14. Lehmann-Horn F, Spittlemeister W, Iaizzo PA, Franke Ch: Veränderrungen der Muskelzellmembran bie Myotoner Dystrophie. In: Diagnosis und Therapieansätze Dei Neuromuskulären Krankhelten. Kunze K, Arct A, Thayssen G (eds.), Gustav Fisher Verlag, Stuttgart, pages 38-43, 1992.

13. Seewald MJ, Eichinger HM, Powis G, Iaizzo PA: Halothane and putative second messenger agents enhance the release of intracellular Ca2+ in hepatocytes prepared from swine susceptible to malignant hyperthermia. Meat Science and Technology 1:473-476, 1991.

12. Wagner A, Iaizzo PA, Lehmann-Horn F: Relation between electrical and mechanical muscle activity in myotonia. Psychiatry Neurology and Medical Psychology 42:569-575, 1990.

11. Lehmann-Horn F, Franke Ch, Iaizzo PA, Klein W, Spieß-Kiefer C: Erkrankungen der Skelett Muskulatur. In: Entwicklungen in der Neurologie. Struppler A, Dengler R (eds.), TM-Verlag, Hameln, pages 25-29, 1990.

10. Lehmann-Horn F, Iaizzo PA, Franke Ch: Hyperexcitability of muscle fibers in Schwartz-Jampel syndrome. In: The Motor Unit: Physiology, Diseases, Regeneration. Dengler R (ed.), Urban and Schwarzenberg, München, FRG, pages 63-70, 1990.

9. Eichinger HM, Seewald MJ, Iaizzo PA: Porcine malignant hyperthermia: new insights into the pathophysiology as it may relate to meat quality. In: Proceedings Vol. III ICOMST. Copenhagen, Denmark, pages 1119-1123, 1989.

8. Lehmann-Horn F, Klein W, Hohne E, Iaizzo PA: In vitro diagnosis of susceptibility to malignant hyperthermia. In: Malignant Hyperthermia, An Update. Proceedings of the VI Myology Colloquium. Hofmann JG, Schmidt A (eds.), Volk and Gesundheit, Berlin, pages 97-100, 1989.

7. Iaizzo PA, Klein W, Lehmann-Horn F: Myoplasmic calcium and contractures in MH susceptible skeletal muscle. In: Malignant Hyperthermia, An Update. Proceedings of the VI Myology Colloquium. Hofmann JG, Schmidt A (eds.), Volk and Gesundheit, Berlin, pages 247-252, 1989.

6. Lehmann-Horn F, Iaizzo PA: Neuromuscular diseases and their relationship to malignant hyperthermia. In: Advances in Neuromuscular Diseases. Serratrice G, Pellissier JF, Desnuelle C, Pouget J (eds.), Expansion Scientifique Francaise, pages 260-266, 1989.

5. Lehmann-Horn F, Iaizzo PA: Use of fiber segments to investigate the pathophysiology of human skeletal muscle. In: Advances in Neuromuscular Diseases. Serratrice G, Pellissier JF, Desnuelle C, Pouget J (eds.), Expansion Scientifique Francaise, pages 44-50, 1989.

4. Lehmann-Horn F, Iaizzo PA: Physiologie der menschlichen skelettmuskulatur: Ergebnisse an routinemäßig entnommenen muskelproben. In: Malignant Hyperthermia. Mauritz W, Bergmann H, Steinbereithner K (eds.), Beiträge zur Anaesthesiiologie unt Intensivmedizin 27:19-23, 1989.

3. Iaizzo PA: The pathophysiology of malignant hyperthermia. Acta Anaesthesiologica Scandinavica 33:45-47, 1989.

2. Eichinger H, Seewald M, Iaizzo PA: Membrane phospholipid concentrations in cardiac and skeletal muscles from normal and malignant hyperthermia susceptible pigs. In: Control and Regulation of Animal Growth. Quirke JF and Schmid H (eds.), EAAP Pub. No. 36, Pudoc, Wageningen, Netherlands, pages 191-200, 1988.

1. Pozos RS, Stauffer EK, Iaizzo PA, Mills W, Howard D, Israel D: Shivering and other forms of tremor. In: Living in the Cold. Heller E (ed.), Elseveir Press, North Holland, Amsterdam, pages 531-537, 1986.

Letters to the Editor

7. Bandschapp O, Soule CL, Urwyler A, Iaizzo PA: Excess hydrogen ion in weaning failure: what are the critical tissue levels? British Journal of Anesthesia, E-letter published 9/20/10 (http://bja.oxfordjournals.org).

6. Ginz HF, Bandschapp O, Urwyler A, Girard T, Iaizzo PA: Tissue oedema is not associated with skeletal muscle weakness in septic patients. Acta Anaesthesia Scandinavica 54:904, 2010. PMID: 20649524

5. McLoon L, Iaizzo PA, Falkenberg J, Dykstra D: Doxorubicin chemomyectomy as a treatment for cervical dystonia (Reply: Letter to the Editor). Muscle and Nerve 22:652-653, 1999.

4. Iaizzo PA, Belani KG, Rosenberg H: VIIIth International workshop on malignant hyperthermia. The American Journal of Anesthesiology 24:40, 1997.

3. Iaizzo PA, Sessler: Skeletal muscle is responsible for heat production in porcine malignant hyperthermia (In Response: Letter to the Editor). Anesthesia and Analgesia 83:1134, 1996.

2. Zink RS, Iaizzo PA: Convective warming therapy does not increase the risk of wound contamination in the operating room. Anaesthesia Digest 3:9, 1993.

1. Lehmann-Horn F, Iaizzo PA: Are myotonias and periodic paralysis associated with susceptibility to malignant hyperthermia? (Correspondence: Reply). British Journal of Anaesthesia 67:221-222, 1991.

Educational Materials

12. Iaizzo PA: U.S. History, 1865 to the Present. Educational CD, Firm Foundations and New Perspectives, Osher Lifelong Learning Institute, College of Continuing Education, University of Minnesota. Presentation on “Technological and Medical Advancements,” 2006.

11. Ellenbogen KA, Kay GN, Wilkoff BL (eds.). Clinical Cardiac Pacing and Defibrillation, 2nd edition. WB Saunders Company, Philadelphia, PA, 2006. Visible Heart pictures are featured in this book.

10. Atlas of Human Cardiac Anatomy: A Web based textbook (www.vhlab.umn.edu/atlas), 2005.

9. Iaizzo PA, Principal Investigator, The Visible HeartTM Viewer. Educational CD, Version 1.2, University of Minnesota and Medtronic, 2004.

8. “Waking up hibernating bears in Washington State,” taped interview for National Public Radio, October 22, 2003. http://www.npr.org/rundowns/segment.php?wfId=1474914

7. Iaizzo PA, Principal Investigator, The Atlas of Human Cardiac Anatomy: Interactive Learning Tool Video Clips; CD Version, University of Minnesota and Medtronic, 2002.

6. Iaizzo PA, Principal Investigator, The Visible Heart CD Version 1.0, University of Minnesota and Medtronic, 2002.

5. “The Bear Evidence,” 50-minute film produced by Henson International Television, shown on National Geographic International, Fall 2001.

4. Iaizzo PA, Principal Investigator, The Visible HeartTM Viewer. Educational CD, Version 1.1, University of Minnesota and Medtronic, December 2000.

3. Iaizzo PA, Principal Investigator, The Visible HeartTM Viewer. Demonstration CD, University of Minnesota and Medtronic, PACE, Volume 23, April 2000.

2. Iaizzo PA, Principal Investigator, The Visible HeartTM: A New View Into the Heart. Demonstration CD, Version 1.0, University of Minnesota and Medtronic, November 1999.

1. Iaizzo PA: Anesthetic complications in patients with skeletal muscle disorders. Practical Reviews in Anesthesiology: Educational Reviews Audio Program, March 1997.