LMP collaboration advances academic-community classification system for endometrial cancer

LMP faculty in collaboration with faculty from the Department of Obstetrics, Gynecology, and Women's Health and the Max Randy College of Medicine, University of Winnipeg have advanced a molecular-risk classification system for endometrial cancer.  

The collaboration was published in the March 7th edition of the American Journal of Clinical Pathology:  "Implementation of endometrial cancer molecular subtyping into a hybrid community-academic practice."  Co-first authors are University of Winnipeg pathologist Elizabeth Ferreira, an LMP Gynecology/Breast Cancer Fellow last year, and Gynecology/Oncology Fellow Alexandra Schefter.  LMP professor Mahmoud Khalifa and associate professors Andrew Nelson and Molly Klein are coauthors.

"This protocol is important because molecular classification of endometrial cancer has shown clear clinical utility for predicting the prognosis (outcome) of individual patient's endometrial cancers," Nelson said.  "Providers can better tune therapy recommendations to each patient based on this information."

Molecular testing has become a critical part of diagnostic classification. 

"Our collaboration was important because the utility data is relatively new, and the testing protocol requires close collaboration between clinical gynecologic oncologists, surgical pathologists, and molecular pathologists to execute appropriately, efficiently, and accurately," Nelson said.