To be a world class division of LMP that provides department, collegiate and national leadership in the pursuit of excellence in molecular pathology and genomic research, education and clinical service.
To foster a culture of innovation and academic excellence by promoting synergistic collaborations among members of the Division of Molecular Pathology and Genomics.
Molecular Pathology and Genomics & Computation Pathology Symposium
May 5, 2021 - Virtual
The "omics" revolution has arrived!
Curious about the revolutionary role of mass spectrometry in personalized medicine? Join the Department of Laboratory Medicine & Pathology’s Divisions of Molecular Pathology and Genomics (MPG) and Computational Pathology (CP) to learn about how the integration of genomics, proteomics, and metabolomics is challenging traditional medical paradigms and creating novel opportunities for improved, personalized patient care.
Dr. Stefani Thomas, University of Minnesota
Dr. Michael Snyder, Stanford University
Computational methods for detection of DNA adducts using mass spectrometry
Dr. Scott Walmsley, University of Minnesota
Highlights of the HUPO Human Proteome Project with an example of proteo-genomics of cancers
Dr. Gil Omenn, University of Michigan
Moderated by Dr. Stefani Thomas, University of Minnesota
2020 MPG/CP Symposium
July 23, 2020
9:00–10:00 - Keynote Speaker 1: Colin Pritchard, MD, PhD
10:00–10:30 - Local Talk 1: Andrew Nelson, MD, PhD
10:30–11:30 - Keynote Speaker 2: Jochen Lennerz, MD, PhD
Medical Director, Center for Integrated Diagnostics, Massachusetts General Hospital
Associate Professor of Pathology, Harvard Medical School
Assistant Pathologist, Pathology, Massachusetts General Hospital
The Use of Artificial Intelligence in the Clinical Report of Genetic Variants at Massachusetts General Hospital
11:30–12:00 - Local Talk 2: Kelsey McIntyre, PhD
Recent MPG Faculty Publications
Andrew C Nelson, Benjamin Auch, Matthew Schomaker, Daryl M Gohl, Patrick Grady, Darrell Johnson, Robyn Kincaid, Kylene E Karnuth, Jerry Daniel, Jess K Fiege, Elizabeth J Fay, Tyler Bold, Ryan A Langlois, Kenneth B Beckman, and Sophia Yohe. Analytical validation of a COVID-19 qRT-PCR detection assay using a 384-well format and three extraction methods. bioRxiv, April 5, 2020. doi: https://doi.org/10.1101/2020.04.02.022186 [preprint]
Yang R, Van Etten JL, Dehm SM. Indel detection from DNA and RNA sequencing data with transIndel. BMC Genomics. 2018 Apr 19;19(1):270. doi: 10.1186/s12864-018-4671-4.
Rashidi A, Nelson AC, Linden MA, Weisdorf DJ, Dolan MM, Ustun C. Genomics of clonal evolution in a case of essential thrombocythemia. Leuk Lymphoma. 2018 Feb;59(2):497-500. doi: 10.1080/10428194.2017.1337113. Epub 2017 Jun 11.
Pérez Ortiz JM, Orr HT. Spinocerebellar Ataxia Type 1: Molecular Mechanisms of Neurodegeneration and Preclinical Studies. Adv Exp Med Biol. 2018;1049:135-145. doi: 10.1007/978-3-319-71779-1_6.
Lou E, D'Souza D, Nelson AC. Therapeutic Response of Metastatic Colorectal Cancer Harboring a KRAS Missense Mutation After Combination Chemotherapy With the EGFR Inhibitor Panitumumab.J Natl Compr Canc Netw. 2017 Apr;15(4):427-432. PMID:28404754
- NIH Director: Genome sequencing: Exploring the diagnostic promise
- NIH Precision Medicine Initiative Cohort Program
- NHGRI: What is genomic medicine?
- NCI: The Precision Medicine Initiative and Cancer
- NCI Laboratory of Pathology
- Association for Molecular Pathology
- "The future of genomics in pathology"
- "The current state of resident training in genomic pathology"