Molecular Pathology & Genomics


To be a world class division of LMP that provides department, collegiate and national leadership in the pursuit of excellence in molecular pathology and genomic research, education and clinical service.

Strategic Intent

To foster a culture of innovation and academic excellence by promoting synergistic collaborations among members of the Division of Molecular Pathology and Genomics.

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2023 MPG Symposium

Molecular Pathology & Genomics Symposium

May 4, 2023, Weisman Art Museum


11:00AM – 12:30PM: 

"Spatially distinct RHAMM-positive niches promote breast tumor invasion"

Dr. Andrew Nelson, University of Minnesota 


"Spatial profiling of melanoma in immunocompromised patients"

Dr. Alessio Giubellino, University of Minnesota 


"Using spatial proteomics to study immune topography"

Dr. Sean Tracy, University of Minnesota 


12:30PM – 2:00PM: 

Lunch Break and Poster Session 


2:00PM – 2:45PM: 

"The tumor-immune microenvironment in situ: a closer look"

Keynote Speaker: Dr. Svetomir Markovic, Mayo Clinic, Rochester, MN            

2:45PM – 3:15PM: 

Panel Discussion


3:15PM – 4:00PM: 

Social Hour/Networking


Poster Session Video Link


Poster Session Winners

  • 1st: Jesenia Perez, Microbiology, Immunology and Cancer Biology (MICaB)             
    “Establishing proteome divergence between high-grade serous ovarian tumors and their patient-derived xenograft experimental models” (Thomas lab)

  • 2nd: Kiel Tietz, Masonic Cancer Center, “Alternative polyadenylation as a therapeutic vulnerability in prostate cancer” (Scott Dehm lab)        

  • 3rd: Samuel Pitzen, Genetics, Cell Biology and Development, “KLF5 drives basal cell identify to promote prostate cancer lineage plasticity” (Scott Dehm lab)            


2021 MPG/CP Symposium

Molecular Pathology and Genomics & Computation Pathology Symposium

May 5, 2021 - Virtual

The "omics" revolution has arrived!

Curious about the revolutionary role of mass spectrometry in personalized medicine? Join the Department of Laboratory Medicine & Pathology’s Divisions of Molecular Pathology and Genomics (MPG) and Computational Pathology (CP) to learn about how the integration of genomicsproteomics, and metabolomics is challenging traditional medical paradigms and creating novel opportunities for improved, personalized patient care.


Dr. Bharat Thyagarajan, University of Minnesota

Session 1- 10:30AM to 11:30AM  
Big Data, Health and COVID-19

Dr. Michael Snyder, Stanford University


Session 2- 11:30AM-12:00PM
Computational methods for detection of DNA adducts using mass spectrometry

Dr. Scott Walmsley, University of Minnesota

Session 3- 12:00PM-1:00PM 
Highlights of the HUPO Human Proteome Project with an example of proteo-genomics of cancers
Dr. Gil Omenn, University of Michigan
Panel Discussion 1:00PM to 1:30PM

Moderated by Dr. Stefani Thomas, University of Minnesota

2020 MPG/CP Symposium

July 23, 2020

9:00–10:00 - Keynote Speaker 1: Colin Pritchard, MD, PhD 

Associate Professor, Genetics
Associate Director, Genetics and Solid Tumors Laboratory
University of Washington Medical Center

10:00–10:30 - Local Talk 1: Andrew Nelson, MD, PhD

Associate Professor, Laboratory Medicine and Pathology
University of Minnesota

The Ovarian Cancer Precision Medicine Initiative

10:30–11:30 - Keynote Speaker 2: Jochen Lennerz, MD, PhD

Medical Director, Center for Integrated Diagnostics, Massachusetts General Hospital
Associate Professor of Pathology, Harvard Medical School
Assistant Pathologist, Pathology, Massachusetts General Hospital

The Use of Artificial Intelligence in the Clinical Report of Genetic Variants at Massachusetts General Hospital 

11:30–12:00 - Local Talk 2: Kelsey McIntyre, PhD

Assistant Professor, Laboratory Medicine and Pathology
University of Minnesota

Clinical Validation of Whole Genome Sequencing for Detection of Structural Variants

Accreditation Statement and Credit Designation Statements

Recent MPG Faculty Publications

Andrew C Nelson, Benjamin Auch, Matthew Schomaker, Daryl M Gohl, Patrick Grady, Darrell Johnson, Robyn Kincaid, Kylene E Karnuth, Jerry Daniel, Jess K Fiege, Elizabeth J Fay, Tyler Bold, Ryan A Langlois, Kenneth B Beckman, and Sophia Yohe.  Analytical validation of a COVID-19 qRT-PCR detection assay using a 384-well format and three extraction methods. bioRxiv, April 5, 2020. doi: [preprint]

Yang R, Van Etten JL, Dehm SM.  Indel detection from DNA and RNA sequencing data with transIndel. BMC Genomics. 2018 Apr 19;19(1):270. doi: 10.1186/s12864-018-4671-4.

Rashidi A, Nelson AC, Linden MA, Weisdorf DJ, Dolan MM, Ustun C. Genomics of clonal evolution in a case of essential thrombocythemia.  Leuk Lymphoma. 2018 Feb;59(2):497-500. doi: 10.1080/10428194.2017.1337113. Epub 2017 Jun 11.

Pérez Ortiz JM, Orr HT. Spinocerebellar Ataxia Type 1: Molecular Mechanisms of Neurodegeneration and Preclinical Studies. Adv Exp Med Biol. 2018;1049:135-145. doi: 10.1007/978-3-319-71779-1_6.

Lou E, D'Souza D, Nelson AC. Therapeutic Response of Metastatic Colorectal Cancer Harboring a KRAS Missense Mutation After Combination Chemotherapy With the EGFR Inhibitor Panitumumab.J Natl Compr Canc Netw. 2017 Apr;15(4):427-432. PMID:28404754