Stem Cell Institute News Search
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SCI faculty evaluate new micromagnetic device for precision neuromodulation
SCI faculty Walter Low (Neurosurgery) and Susan Keirstead (Integrative Biology and Physiology) collaborated with colleagues Theoden Netoff (Biomedical Engineering) and Jian-Ping Wang (Electrical and...
Stem Cell

Former Stem Cell Institute Director, Jonathan Slack, PhD Awarded Wolpert Medal by the British Society for Developmental Biology
The Wolpert Medal "is presented to an individual who has made extraordinary contributions to the teaching and communication of Developmental Biology". Jonathan Slack, who was director of the...
Stem Cell

SCI Researchers are Genetically Engineering Underexplored Gamma delta T-cells to Attack Solid Tumors
SCI faculty member Beau Webber recently received a CURE Childhood Cancer grant award to test genetically engineered gamma delta T-cells against solid tumors, like osteosarcoma, a...
Stem Cell

SCI Faculty Mark Osborn has been Awarded Saint Baldrick Foundation Funding to Support Gene and Cell Engineering Research
Dr. Osborn will use this grant to continue his work on engineering chimeric antigen receptor (CAR) T-cells that will more specifically target cancerous B-cells while minimizing damage to healthy...
Stem Cell

SCI Innovation Space Update
The vision for the McGuire Translational Research Facility (MTRF), the building that is home to the Stem Cell Institute, was always that it would be a place where promising medical research would be...
Stem Cell

University of Minnesota and Mayo Clinic Collaborative Retreat on Organoids and Engineered Tissue Models
On April 18, 2023 the University of Minnesota Stem Cell Institute and Institute for Engineering in Medicine partnered with the Mayo Clinic Cells 2 Cures Initiative to sponsor a one-day retreat-...
Stem Cell

Proliferation and Maturation: Janus and the Art of Cardiac Tissue Engineering
In this work, our emerging understanding of proliferation and maturation of cardiomyocytes is described with an emphasis on the fact that both processes are necessary but do not seem to be able...
Stem Cell

Parsing the Biochemical Signals Dictating Patterning During Development
During development stem cells are induced to differentiate and give rise to structures like limbs as a result of chemical gradients established in the tissues. Hiroshi Nakato,...
Stem Cell, Research

Gearing up for Preclinical Trials for Skeletal Muscle Stem Cells
SCI faculty member Rita Perlingeiro is at the forefront of research on the generation of skeletal muscle stem cells from human induced pluriptotent stem cells. These cells...
Stem Cell, Research

Using Stem Cells to Understand Cardiac Development and Address Heart Birth Defects
Congenital cardiac diseases are among the most common birth defects and can have devastating consequences perinatally as well as throughout the lifetime of the individual. A clear understanding...
Stem Cell, Research

SCI Faculty Strengths in Skeletal Muscle Stem Cell Research Showcased
Skeletal muscle stem cells are responsible for muscle repair after exercise or injury and are a potential source of cells for transplantation therapies for individuals suffering from muscle diseases...
Stem Cell, Research

Stopping Cancer Stem Cells in Their Tracks
Cancer stem cells found in tumors can evade chemotherapeutic treatments and go on to reestablish and/or metastasize and form new tumors in other tissues. Paolo Provenzano and...
Stem Cell, Research

SCI Researchers Seek to Optimize Blastocyst Complementation to Generate Human Organs in Pigs
The shortage of organs and tissues for transplants has led researchers in the Stem Cell Institute to investigate the possibility of making human organs in animals by injecting human pluripotent stem...
Stem Cell

SCI Faculty Brenda Ogle and Michael McAlpine Develop New Cryoablation Test Bed
Engineered human tissue models have been proposed as a means to test the performance of medical devices and the impact of device intervention on tissue health and function.
Stem Cell, Faculty, Research

SCI Faculty Troy Lund, MD, PhD refines decision-making process for hematopoietic cell transplant treatment of Hurler's Syndrome
Hurler's Syndrome is caused by a mutation in a gene (IDUA) that encodes an enzyme that is responsible for clearing cellular waste products, and hence prevents accumulation of toxic...
Stem Cell, Faculty, Research

Walter Low and colleagues receive new NIH funding to study the relationship between the SARS-CoV2 virus and long term neurological disease.
Walter Low, SCI faculty member, Ling Li, and Maxim Cheeran received a 5-year NIH grant to study the acute and long-term impact of SARS-CoV2 infection on cognitive function and neuropathology in...
Stem Cell

Casim Sarkar, SCI faculty member, advances DNA editing techniques for personalized cell therapies
Dr. Sarkar's biomedical engineering team has leveraged machine learning and high-throughput experiments to control the speed at which therapeutic cells respond to their environment. Read the...
Stem Cell

Stem Cell Institute Predoctoral Infuse Award Program Activities are Underway
The Predoctoral Infuse Awards program was initiated by the Stem Cell Institute in May 2021. The program aims to create a community of PhD trainees and faculty who meet regularly to discuss...
Stem Cell