Georgios Manousakis, MD

Assistant Professor,

Georgios Manousakis

Contact Info

Office Phone Clinic: 612-626-6688

Administrative Assistant Name
Cathie Witzel

Administrative Phone

Administrative Email

Administrative Fax Number

Assistant Professor


MD, University of Athens Medical School

Residency in Neurology, University of Wisconsin Hospital

Preliminary Residency in Internal Medicine, Maimonides Medical Center

Fellowship in Neuromuscular Medicine, Washington University


I have been Assistant Professor of Neurology at the University of Minnesota since 2012, and Director of the Neuromuscular Medicine Fellowship Program since 2017. My priorities include offering exceptional clinical care for patients with neuromuscular diseases, providing the most up-to-date neuromuscular education to students, residents, and fellows, and researching new therapeutic options for neuromuscular conditions that represent unmet medical needs, with a specific focus on myopathies of adults and ALS. 


Amyotrophic lateral sclerosis

Adult onset spinal muscular atrophy

Peripheral neuropathy

Neuromuscular junction disorders including myasthenia gravis

Muscular dystrophies of adults

Acquired myopathies of adults, including myositis

Awards & Recognition

AB Baker Teacher Recognition Award, American Academy of Neurology, 2019

William Kennedy Teaching Award, University of Minnesota Department of Neurology, 2014, 2018

Top Doctors, Rising Stars- Minneapolis & St Paul Magazine, 2015, 2016, 2017


Research Funding Grants


Greg Marzolf Jr Foundation

Serum uric acid as biomarker of type I myotonic dystrophy


1.Cheong I, Deelchand DK, Eberly LE, Marja?ska M, Manousakis G, Guliani G, Walk D, Öz G. Neurochemical correlates of functional decline in amyotrophic lateral sclerosis.J Neurol Neurosurg Psychiatry. 2019 Mar;90(3):294-301.

2.McClelland C, Manousakis G, Lee MS. Progressive External Ophthalmoplegia. Curr Neurol Neurosci Rep. 2016 Jun;16(6):53.

3.Miller TM, Pestronk A, David W, Rothstein J, Simpson E, Appel SH, Andres PL, Mahoney K, Allred P, Alexander K, Ostrow LW, Schoenfeld D, Macklin EA, Norris DA, Manousakis G, Crisp M, Smith R, Bennett CF, Bishop KM, Cudkowicz ME. An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study. Lancet Neurol. 2013 May;12(5):435-42.

4.Sattar A, Manousakis G, Jensen MB. Systematic review of reversible cerebral vasoconstriction syndrome. Expert Rev Cardiovasc Ther. 2010 Oct;8(10):1417-21.

5.Oczko-Walker M, Manousakis G, Wang S, Malter JS, Waclawik AJ. Plasma exchange after initial intravenous immunoglobulin treatment in Guillain-Barré syndrome: critical reassessment of effectiveness and cost-efficiency. J Clin Neuromuscul Dis. 2010 Dec;12(2):55-61



Neurology Clinic

Board Certifications

Neurology; Neuromuscular Medicine, Clinical Neuromuscular Pathology

Clinical Interests

ALS Peripheral neuropathy Neuromuscular junction disorders Muscular dystrophies of adults Acquired myopathies of adults